Program Manager Jobs in St. Louis, MO

Program Manager jobs in St. Louis are concentrated in the Central West End, Clayton, and downtown's Midtown Corridor, with strong demand across healthcare, defense contracting, and financial services. Employers hiring right now include WM, YMCA, and Ascension. Scan the live roles below and apply to whichever ones fit.

Find Program Manager Jobs

Overview

Open roles56
Top employerWM
Work type54% Remote
Top credentialBachelor's degree
Companies hiring17

Showing 4 of 56+ Program Manager jobs

Before and After School Program Manager - South St. Louis School Districts
We won't show you this job again
Added 3d ago
Before and After School Program Manager - South St. Louis School Districts
Right at School
St. Louis, Missouri
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
$21 - $26/hr
CPR Certification

Have you applied for this role?

National Warehouse Security Program Manager
We won't show you this job again
Added 3d ago
National Warehouse Security Program Manager
GardaWorld Security Services US
St. Louis, Missouri
Business Development
Corporate Development & M&A
Investment Operations
Procurement & Purchasing
$100k - $110k/yr
Remote (US)
Bachelor's degree
1,001-5,000

Have you applied for this role?

Aquatics Program Manager - Carondelet Park Rec Complex YMCA
We won't show you this job again
Added 4d ago
Aquatics Program Manager - Carondelet Park Rec Complex YMCA
YMCA
St. Louis, Missouri
Business Operations
Business Strategy
Project Management
$17 - $19/hr
51-200

Have you applied for this role?

Program Manager, United for Families
We won't show you this job again
Added 1w ago
Program Manager, United for Families
United Way
St. Louis, Missouri
Business Strategy
Data Analytics
Data Science
Hybrid
Master's degree in social work
11-50

Have you applied for this role?

See All 56 Program Manager Jobs in St. Louis

Find roles in St. Louis that match your experience and apply in just a few clicks.

Find Program Manager Jobs

Program Manager Job Market in St. Louis

Who's Hiring

WM3 open roles
YMCA3 open roles
Ascension3 open roles

Program Manager Jobs in St. Louis: Frequently Asked Questions

How do I get a program manager job in St. Louis?

Your strongest entry point is the healthcare and life sciences cluster anchored in the BJC HealthCare and Washington University medical corridor, followed by defense and government contracting firms based in the St. Louis Metro East and Hazelwood areas. Employers here weight PMP certification, experience managing cross-functional stakeholders, and familiarity with federal or clinical compliance frameworks. Networking through the St. Louis chapter of PMI gives you direct access to hiring managers in those concentrations.

Which companies hire program managers in St. Louis?

Companies currently hiring program managers in St. Louis include WM, YMCA, and Ascension, per current listings on Migrate Mate as of November 2026. St. Louis draws a mix of large health systems, aerospace and defense contractors, and regional financial institutions, all of which maintain ongoing program management needs across multi-year initiatives.

Are there remote program manager jobs in St. Louis?

Yes, though availability depends heavily on the sector. About 77% of program manager openings tied to St. Louis are remote or hybrid as of November 2026, skewing toward roles in software, consulting, and financial operations rather than defense or clinical settings that require on-site presence. Hybrid schedules anchored to Clayton or downtown offices are the most common arrangement.

How can I get a program manager job in St. Louis with little or no experience?

The most realistic path in St. Louis is starting as a project coordinator or associate project manager inside a large health system, a regional bank, or a defense contractor, then building toward a full program manager title. Employers like those in the BJC or SSM Health networks regularly hire coordinators who can demonstrate process ownership. A CAPM certification and volunteer leadership with a St. Louis nonprofit portfolio round out an entry-level application effectively.

See All 56 Program Manager Jobs in St. Louis

Find roles in St. Louis that match your experience and apply in just a few clicks.

Find Program Manager Jobs