Program Manager Jobs in St. Louis, MO

Program Manager jobs in St. Louis are concentrated in the Central West End, Clayton, and downtown's Midtown Corridor, with strong demand across healthcare, defense contracting, and financial services. Employers hiring right now include Washington University in St. Louis, BJC HealthCare, and World Wide Technology. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles38
Top employerWashington University in St. Louis
Work type50% Hybrid
Top credentialBachelor's degree
Companies hiring25

Showing 5 of 38+ Program Manager jobs

Thermo Fisher Scientific
Manager, Program Management - Remote US
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Thermo Fisher Scientific
New 1m ago
Manager, Program Management - Remote US
Thermo Fisher Scientific
St. Louis, Missouri
Logistics & Fleet Management
Procurement & Supply Chain
Supply Chain
Remote (US)
Bachelor's degree in business
10,000+

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SSM Health
Registered Nurse Program Manager - Nursing Administration
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SSM Health
New 1m ago
Registered Nurse Program Manager - Nursing Administration
SSM Health
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification
10,000+

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Washington University in St. Louis
Clinical Program Manager - Psychiatry
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Washington University in St. Louis
New 1m ago
Clinical Program Manager - Psychiatry
Washington University in St. Louis
St. Louis, Missouri
Business Operations
Project Management
Quality Assurance & Testing (QA Testing)
$62k - $96k/yr
Master's degree in social work
10,000+

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Chameleon Integrated Services
Sr. Program Manager
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Chameleon Integrated Services
New 1m ago
Sr. Program Manager
Chameleon Integrated Services
St. Louis, Missouri
Program Management
Project & Program Management
Project Management
Remote (US)
Bachelor's degree in management information systems
201-500

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Washington University in St. Louis
Senior Manager Social Services Program - Psychiatry
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Washington University in St. Louis
New 1m ago
Senior Manager Social Services Program - Psychiatry
Washington University in St. Louis
St. Louis, Missouri
Customer Service
Healthcare Administration
Human Resources
Social Work & Counseling
$75k - $116k/yr
Master's degree
10,000+

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See All 38 Program Manager Jobs in St. Louis

Find roles in St. Louis that match your experience and apply in just a few clicks.

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Program Manager Job Market in St. Louis

Who's Hiring

  • Washington University in St. Louis
    Washington University in St. Louis7
  • BJC HealthCare
    BJC HealthCare4
  • World Wide Technology
    World Wide Technology4
  • SSM Health
    SSM Health2
  • S
    sse1

Top Industries Hiring

  • Education8
  • Technology & Software5
  • Healthcare & Medical Services2
  • Food & Beverage1
  • Distribution & Wholesale1

Program Manager Jobs in St. Louis: Frequently Asked Questions

How do I get a program manager job in St. Louis?

Your strongest entry point is the healthcare and life sciences cluster anchored in the BJC HealthCare and Washington University medical corridor, followed by defense and government contracting firms based in the St. Louis Metro East and Hazelwood areas. Employers here weight PMP certification, experience managing cross-functional stakeholders, and familiarity with federal or clinical compliance frameworks. Networking through the St. Louis chapter of PMI gives you direct access to hiring managers in those concentrations.

Which companies hire program managers in St. Louis?

Companies currently hiring program managers in St. Louis include Washington University in St. Louis, BJC HealthCare, and World Wide Technology, per current listings on Migrate Mate as of July 2026. St. Louis draws a mix of large health systems, aerospace and defense contractors, and regional financial institutions, all of which maintain ongoing program management needs across multi-year initiatives.

Are there remote program manager jobs in St. Louis?

Yes, though availability depends heavily on the sector. About 75% of program manager openings tied to St. Louis are remote or hybrid as of July 2026, skewing toward roles in software, consulting, and financial operations rather than defense or clinical settings that require on-site presence. Hybrid schedules anchored to Clayton or downtown offices are the most common arrangement.

How can I get a program manager job in St. Louis with little or no experience?

The most realistic path in St. Louis is starting as a project coordinator or associate project manager inside a large health system, a regional bank, or a defense contractor, then building toward a full program manager title. Employers like those in the BJC or SSM Health networks regularly hire coordinators who can demonstrate process ownership. A CAPM certification and volunteer leadership with a St. Louis nonprofit portfolio round out an entry-level application effectively.

Which industries hire the most program managers in St. Louis?

The sectors hiring the most program managers in St. Louis are Education, Technology & Software, and Healthcare & Medical Services, based on current listings on Migrate Mate as of July 2026. St. Louis's concentration of major hospital networks, legacy aerospace and defense firms, and a growing fintech presence makes these sectors the consistent drivers of local program management demand.

See All 38 Program Manager Jobs in St. Louis

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