Project Director Jobs in Massachusetts
Project Director jobs in Massachusetts are open across Boston, Cambridge, and Waltham and other Massachusetts metros, with employers like Alvarez & Marsal, Biogen, and Dana-Farber Cancer Institute hiring at every experience level. Find a role that fits below and apply directly.
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About the role
Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who want to challenge status quo, and who lead with the desire to work on novel ideas. As an Associate Director, Project Management, you will report to the program team lead (PTL) and work directly with our functional leaders to coordinate research, development, and manufacturing activities for Sana’s in vivo CAR T cell engineering program. You’ll help us target those small details that unlock big successes. This is a hybrid role that requires onsite presence at least 3 days a week in Cambridge.
What you’ll do
- Partner with the PTL to manage a complex, cross-functional in vivo CAR T cell engineering program from preclinical through clinical development.
- Owner of project plan templates, tools, and project management best practices to organize and facilitate program team activities.
- Create and maintain a comprehensive project timeline and dashboard to monitor program performance, identify risks, and implement mitigation strategies in real time.
- Maintain close collaboration and great communication with internal and external key stakeholders to track program milestones where critical path risks at CDMO, CTL, and CRO are identified, escalated, and resolved promptly.
- Manage development and program budget.
What we’re looking for
- Batchelor’s degree in life sciences, biotechnology, or engineering field
- 6+ years of experience in pharmaceutical or life sciences industry, including 3+ years direct project management experience
- Proficiency in project management methodologies and tools such as Smartsheet and MS Timeline
- Excellence in stakeholder management with track record of working in matrix organization and influencing across multi-site, multi-function project teams
- Flexibility to work with external vendors in various time zones
- Strong understanding of drug development lifecycle and compliance in biotechnology
- Ability to operate effectively in a dynamic start-up environment that requires learning agility and the ability to plan and execute through ambiguity
What will separate you from the crowd
- PM Experience in Cell and Gene Therapy development
- PMP certification
- Global experience
What you should know
- The base pay range for this position at commencement of employment is expected to be between $160,000 and $200,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience
How we work together for patients
- Lead from every seat – we seek to understand, act with honesty, and engage in the crucial conversations
- Thrive as a team – we hire amazing people, are intensely curious, and cultivate inclusion and personal connectivity
- Make it happen – we value vigorous debate, alignment around our decisions, and resilient execution
Get to know us
At Sana, we believe that a workforce with varied backgrounds strengthens us as a company and helps us to achieve our mission to meaningfully change the outcome of many human diseases. This belief is a pillar of our business and is critical to our success. Our goal is that Sana is the place for talented people to bring their authentic selves to work, to have a great career and to deeply, positively impact patients. Core to our values, we believe there is nothing more important than the health and wellness of you and your family. For benefit eligible employees, we cover a generous portion of the cost for employee health coverage, making high-quality care more accessible and affordable. We offer ample time-off (various paid time off benefits, such as holidays, vacation, sick time, and parental leave), short- and long-term disability, employer paid basic life insurance, additional voluntary life insurance protection, financial wellness programs including financial planning resources, a 401(k) Plan with an immediately vested employer match, Tuition Reimbursement and Student Loan Repayment, Employee Stock Purchase Plan, commuter subsidy and a variety of wellness offerings to support each person individually.
We are committed to providing a workplace free of discrimination and harassment based on race, color, religion, age, gender, national origin, ancestry, physical or mental or sensory disability (including the use of a trained guide dog or service animal by a person with a disability), genetic information, actual or perceived HIV or Hepatitis C infection, medical condition (cancer or a record or history of cancer and genetic characteristics), marital status, sexual orientation, sexual preference, pregnancy (including childbirth and related medical conditions), disability, veteran status, political ideology, social class (including caste/caste identity), taking or requesting statutorily protected leave, status as a victim of domestic violence, sexual assault or stalking, or any other basis prohibited by applicable law. To perform this job successfully, you must be able to perform each job responsibility satisfactorily. The job description listed above is representative of the knowledge, skills, and/or abilities required for this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the functions described above.
See All 576+ Project Director Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Project Director JobsProject Director Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Project Director Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
- Alvarez & Marsal23

- Biogen17

- Dana-Farber Cancer Institute17

- Dyne Therapeutics16

- Beth Israel Lahey Health12

Top Industries Hiring
- Biotechnology & Pharmaceuticals154
- Healthcare & Medical Services91
- Education67
- Consulting & Professional Services63
- Science & Research58
What Massachusetts Employers Look For
The qualifications that appear most often in project director jobs across Massachusetts.
- PMP certification or equivalent program management credential required
- 7-plus years leading cross-functional programs from initiation through delivery
- Experience managing project budgets in the multi-million-dollar range
- Proficiency with project management platforms such as MS Project, Smartsheet, or Jira
- Bachelor's degree in business, engineering, or a related field
- Strong stakeholder communication and executive reporting experience
Project Director Jobs in Massachusetts: Frequently Asked Questions
How many project director jobs are there in Massachusetts?
There are 576+ project director openings in Massachusetts on Migrate Mate as of June 2026, with the most roles in Boston, Cambridge, and Waltham. New positions post regularly as employers across Massachusetts hire.
How much do project directors make in Massachusetts?
Project directors in Massachusetts earn a median of about $114,190 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $72,800 for the lowest 10% to over $174,840 for the top 10%. Pay rises with experience, specialty, and employer.
Which Massachusetts cities have the most project director jobs?
Boston, Cambridge, and Waltham have the most project director openings in Massachusetts right now, with additional roles spread across smaller metros statewide.
Which companies hire project directors in Massachusetts?
Employers hiring project directors in Massachusetts include Alvarez & Marsal, Biogen, and Dana-Farber Cancer Institute, based on current listings on Migrate Mate as of June 2026.
Are there remote project director jobs in Massachusetts?
Yes. About 36% of project director openings tied to Massachusetts are remote or hybrid as of June 2026. The rest are on-site roles based in Massachusetts metros.
How do I apply for project director jobs in Massachusetts?
You can apply to project director jobs in Massachusetts directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Massachusetts location, then apply to each one that fits.
See All 576+ Project Director Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Project Director Jobs