Research Scientist Jobs in Virginia
Research Scientist jobs in Virginia are among the most active in the country, concentrated in defense and national security research, life sciences, and applied technology, with openings at every level from entry-level research associate through senior principal scientist. The heaviest hiring is in the Northern Virginia corridor, Richmond, and the Hampton Roads area, where organizations like Leidos, MITRE, and the Biomedical Advanced Research and Development Authority maintain a sustained presence. The most in-demand specialties include computational biology, materials science, and data-driven defense research. Find a role that fits below and apply directly.
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- 45002736
- 907 Floyd Avenue, MCV Main Campus, Virginia, United States, 23284
- SVP Health Sciences SML
- Research
- Full-Time (Salaried)
- Virginia Commonwealth University
Advertising Summary: Virginia Commonwealth University (VCU) School of Medicine is a premier academic medical center located in the heart of Richmond. Accounting for almost half of VCU’s sponsored research, the School of Medicine is internationally recognized for patient care and education. Virginia Commonwealth University is an equal opportunity employer.
Unit: School Of Medicine MBU
Department: Microbiology and Immunology
Department Summary: Located on the MCV Campus in downtown Richmond, the Department of Microbiology and Immunology is home to a vibrant community of researchers, educators and learners. With a strong history of research funding, our department strives to advance scientific knowledge in the biomedical sciences and inform medical advancements that improve patient outcomes. Our innovative studies span a broad spectrum of areas within the fields of microbiology and immunology:
Allergy and autoimmunity
Host-pathogen interactions and molecular pathogenesis
Human microbiome science and microbial genomics
Reproductive immunology
T-cell therapy and vaccine development
Tumor biology, cell signaling and epigenetics
As educators, we are proud to provide a collaborative, collegial learning environment for our students. Faculty and postdoctoral fellows serve as dedicated mentors, providing an individualized educational experience and shaping the next generation of successful scientists.
Duties & Responsibilities:
A research scientist position (contingent on extramural funding) is available in the laboratory of Dr. Jason A. Carlyon in the Department of Microbiology and Immunology at Virginia Commonwealth University. The successful candidate will participate in NIH-funded projects studying the obligate intracellular bacterial pathogens, Orientia tsutsugamushi and Anaplasma phagocytophilum. Projects include developing genetic tools for O. tsutsugamushi; examining how O. tsutsugamushi modulates multiple host cell processes including immunity, membrane trafficking, cell cycle, apopotosis, lipid signaling, epigenetic gene regulation, and the ubiquitin-proteasome system; examining how A. phagocytophilum-host cell interactions drive bacterial binding, invasion, fitness, intracellular survival, immunity evasion, parasitism, and egress. Highly motivated, hard-working, and technically skilled applicants with relevant experience are welcomed to apply.
Core Responsibilities:
- Maintenance of Orientia tsutsugamushi and Anaplasma phagocytophilum infected cultures
- Maintain uninfected, O. tsutsugamushi infected, and A. phagocytophilum infected cell lines under sterile conditions on a bi-weekly basis
- Assessment of O. tsutsugamushi molecular pathogenesis
- Involves purifying O. tsutsugamushi bacteria from infected cells, contributing to the development of genetic tools for O. tsutsugamushi, performing infection assays under various conditions, assessing infectivity in naïve cells. Diligently keep laboratory notebook and electronic record on server of all experiments
- Assessment of A. phagocytophilum interactions with eukaryotic host cells and mammalian hosts
- Will include all or some of the following: assess A. phagocytophilum adhesin-receptor interactions and how this promote host cell signaling, effector delivery, cytoskeletal rearrangement, and bacterial entry; analyze exosome protein, nucleotide, and lipid profiles; assess A. phagocytophilum modulation of exosome content and effector function; assess A. phagocytophilum pathogenesis using the mouse model. Diligently keep laboratory notebook and electronic record on server of all experiments
- Lab management
- Mentor and train junior scientists. Contribute to daily lab management and maintenance
- Writing manuscripts, grants, abstracts
- Write and edit drafts of manuscripts for publication. Write/contribute data for extramural grant proposals. Writing for both grants and abstracts is expected to be at or near principal investigator quality and maturity. Write abstracts of research and present at scientific conferences
- Demonstrated ability to work in and foster an environment of respect, professionalism and civility with a population of faculty, staff, and students from all backgrounds and experiences, or a commitment to do so as a staff member at VCU
Qualifications:
Minimum Qualifications
(1) PhD or MD/PhD, (2) At least four years of postdoctoral experience and a proven publication record, (3) Experience in working with obligate intracellular bacterial pathogens, (3) Strong background in cell biology, microscopy, biochemistry, molecular biology, and bacterial genetics. (4) Candidates are expected to be very motivated for career development, committed to driving federally funded high impact and high-quality research, and must aggressively pursue extramural funding in the form of NIH R-awards or comparable. (5) Candidates must be able to work independently, be willing to mentor and train junior scientists, and share duties with other staff members in running lab logistics on a daily basis. (6) Candidates are expected to have excellent manuscript and grant writing skills and be extremely committed to becoming independent in these skills. (7) Candidates are expected to demonstrate excellent oral communication skills.
Preferred Qualifications
(1) Experience in working with/cultivating Orientia tsutsugamushi and Anaplasma phagocytophilum in eukaryotic tissue culture. (2) Experience in developing genetic tools for O. tsutsugamushi and/or A. phagocytophilum. (3) Experience in using confocal microscopy, electron microscopy, structured illumination microscopy, immunofluorescence microscopy, and live cell imaging to study obligate intracellular bacteria-host cell interactions. (4) Experience in using Fiji, other imaging software, and writing custom scripts to achieve cutting-edge image analysis. (5) Experience in studying obligate intracellular bacterial development, preferably Anaplasma, Orientia, and related pathogens such as Chlamydia. (6) Experience performing infection assays using intracellular bacterial pathogens. (8) Transfection, siRNA, CRISPR.
Salary Range: $75,000-$78,000
Benefits: All full-time university staff are eligible for VCU’s robust benefits package that includes comprehensive health benefits, paid annual and holiday leave, generous tuition benefits, retirement planning and savings options, tax-deferred annuity and cash match programs, employee discounts, well-being resources, abundant opportunities for career development and advancement, and more.
FLSA Exemption Status: Exempt
Hours per Week: 40
Restricted Position: This is a restricted position with no set end date; continued employment is dependent upon project need, availability of funding, and performance.
ORP Eligible: Yes
Flexible Work Arrangement: Fully Onsite
University Job Title: Research Scientist 1-3 (33241-33243)
Contact Information:
Contact Name: Jason Carlyon, Ph.D.
Contact Email: jason.carlyon@vcuhealth.org
See All 29 Research Scientist Jobs in Virginia
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Find Research Scientist JobsResearch Scientist Jobs by City in Virginia
Where Virginia roles are concentrated, by current openings.
Research Scientist Job Market in Virginia
A snapshot from current Virginia openings, updated as new roles post.
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What Virginia Employers Look For
The qualifications that appear most often in research scientist jobs across Virginia.
- PhD or master's degree in a relevant scientific discipline required by most Virginia postings
- Active security clearance or eligibility to obtain one for federal contractor roles
- Demonstrated publication record or applied research portfolio in a core specialty area
- Proficiency with statistical analysis software such as R, Python, MATLAB, or SAS
- Experience collaborating with federal agencies or within a government-funded research environment
- Strong written communication skills for grant proposals, technical reports, and peer review
Research Scientist Jobs in Virginia: Frequently Asked Questions
How do you become a research scientist in Virginia?
Most research scientist positions in Virginia require at minimum a master's degree, and the large majority of senior roles require a PhD in a relevant scientific field. Virginia does not issue a state research scientist license, so hiring is credential and portfolio driven. Federal contractor roles in Northern Virginia frequently add a security clearance requirement, and candidates pursuing those positions should begin the clearance process early through a sponsoring employer.
Which companies hire research scientists in Virginia?
Employers hiring research scientists in Virginia right now include University of Virginia, Virginia Commonwealth University, and Virginia Tech, based on current listings on Migrate Mate as of November 2026. Virginia's dense concentration of federal agencies and defense contractors means many of the largest and most consistent employers are organizations that hold long-term government research contracts.
Which Virginia cities have the most research scientist jobs?
Charlottesville, Virginia, and Arlington have the most research scientist openings in Virginia. Northern Virginia dominates due to its proximity to federal agencies and the Pentagon, which drives demand from defense contractors and federally funded research centers, while Richmond anchors life sciences and pharmaceutical research, and Hampton Roads supports significant naval and oceanographic research activity.
Are there remote research scientist jobs in Virginia?
Yes, but they're less common than in purely desk-based fields because much research scientist work requires laboratory access, secure facilities, or classified environments. About 25% of research scientist openings tied to Virginia are remote or hybrid as of November 2026, with data analysis, computational modeling, and technical writing components being the most likely to allow off-site work.
How can I get hired as a research scientist in Virginia with little or no experience?
The most realistic entry path is a postdoctoral appointment or a research associate role at one of Virginia's universities or federally funded research centers, such as Virginia Tech's research institutes, George Mason University's affiliated labs, or contract research organizations in the Northern Virginia corridor. Building a portfolio of published work or technical reports, obtaining any entry-level security clearance sponsorship from a federal contractor, and targeting associate scientist or junior analyst titles are the most direct routes into the field without an established record.
Where can I find and apply to research scientist jobs in Virginia?
You can find and apply to research scientist jobs in Virginia on Migrate Mate, which lists current Virginia openings across defense, life sciences, and applied research. Find roles that fit your background and apply directly to the employers posting them.
See All 29 Research Scientist Jobs in Virginia
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