Senior AI Software Engineer Jobs in Missouri

Senior AI Software Engineer jobs in Missouri are open across St Louis, Creve Coeur, and Springfield and other Missouri metros, with employers like Scale AI, Bass Pro Shops, and Cigna-Evernorth Services hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles7+
Top employerScale AI
Top citySt Louis, MO
Cities hiring4
Work type71% On-site
Top industryTechnology

Showing 5 of 7+ Senior AI Software Engineer jobs

Bass Pro Shops
Senior AI Engineer
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Bass Pro Shops
Added 3w ago
Senior AI Engineer
Bass Pro Shops
Springfield, Missouri
Software Engineering
Data Science & Analytics
Data Engineering
Cloud & DevOps
AI (Artificial Intelligence)
ML (Machine Learning)
Data Science
On-Site
Bachelor's
10,000+

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World Wide Technology
Senior Product Manager, AI
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World Wide Technology
Added 2w ago
Senior Product Manager, AI
World Wide Technology
St. Louis, Missouri
Product Management
Software Engineering
Strategy & Corporate Development
Project & Program Management
AI (Artificial Intelligence)
Business Strategy
Program Management
$131k - $164k/yr
On-Site
Bachelor's
10,000+

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Cigna-Evernorth Services
AI Product Manager Senior Advisor – Enterprise Operating Model (EOM)
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Cigna-Evernorth Services
Added 2mo ago
AI Product Manager Senior Advisor – Enterprise Operating Model (EOM)
Cigna-Evernorth Services
St Louis, Missouri
Product Management
Software Engineering
Strategy & Corporate Development
Project & Program Management
Consulting & Professional Services
AI (Artificial Intelligence)
Business Strategy
Remote (US)
High School

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Cushman & Wakefield
Senior Director Data Science and AI
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Cushman & Wakefield
Added 1mo ago
Senior Director Data Science and AI
Cushman & Wakefield
Creve Coeur, Missouri
Data Science & Analytics
Software Engineering
Technical Product & Program Management
Project & Program Management
Data Science
AI (Artificial Intelligence)
ML (Machine Learning)
Technical Program Management
Project Management
$204k - $240k/yr
On-Site
Bachelor's
10,000+

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YASH Technologies
Senior Machine Learning Engineer
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YASH Technologies
Added 3w ago
Senior Machine Learning Engineer
YASH Technologies
St Louis, Missouri
Data Science & Analytics
Software Engineering
Technical Product & Program Management
Data Science
AI (Artificial Intelligence)
ML (Machine Learning)
Hybrid
Bachelor's

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See All 7 Senior AI Software Engineer Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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Senior AI Software Engineer Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St Louis
4 jobs
Creve Coeur
1 jobs
Springfield
1 jobs
St. Louis
1 jobs

Senior AI Software Engineer Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

  • Scale AI
    Scale AI2
  • Bass Pro Shops
    Bass Pro Shops1
  • Cigna-Evernorth Services
    Cigna-Evernorth Services1
  • Cushman & Wakefield
    Cushman & Wakefield1
  • World Wide Technology
    World Wide Technology1

Top Industries Hiring

  • Technology & Software4
  • Construction & Real Estate1
  • Insurance1
  • Retail1

What Missouri Employers Look For

The qualifications that appear most often in senior AI software engineer jobs across Missouri.

  • Advanced degree or equivalent experience in computer science, machine learning, or a related field
  • Production experience designing, training, and deploying large-scale machine learning models
  • Proficiency in Python and at least one deep learning framework such as PyTorch or TensorFlow
  • Hands-on experience with cloud ML platforms including AWS SageMaker, Google Vertex AI, or Azure ML
  • Demonstrated ability to lead technical projects and mentor junior engineers across the AI stack
  • Familiarity with MLOps tooling, model monitoring, and CI/CD pipelines for ML systems

Senior AI Software Engineer Jobs in Missouri: Frequently Asked Questions

How many senior AI software engineer jobs are there in Missouri?

There are 7+ senior AI software engineer openings in Missouri on Migrate Mate as of June 2026, with the most roles in St Louis, Creve Coeur, and Springfield. New positions post regularly as employers across Missouri hire.

How much do senior AI software engineers make in Missouri?

Senior AI software engineers in Missouri earn a median of about $126,120 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $72,570 for the lowest 10% to over $169,340 for the top 10%. Pay rises with experience, specialty, and employer.

Which Missouri cities have the most senior AI software engineer jobs?

St Louis, Creve Coeur, and Springfield have the most senior AI software engineer openings in Missouri right now, with additional roles spread across smaller metros statewide.

Which companies hire senior AI software engineers in Missouri?

Employers hiring senior AI software engineers in Missouri include Scale AI, Bass Pro Shops, and Cigna-Evernorth Services, based on current listings on Migrate Mate as of June 2026.

Are there remote senior AI software engineer jobs in Missouri?

Yes. About 29% of senior AI software engineer openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.

How do I apply for senior AI software engineer jobs in Missouri?

You can apply to senior AI software engineer jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.

See All 7 Senior AI Software Engineer Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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