Senior Clinical Project Manager Jobs in Kentucky

Senior Clinical Project Manager jobs in Kentucky are concentrated in the state's pharmaceutical manufacturing, medical device, and academic medical research sectors, with demand driven by institutions and corporations anchored in Louisville, Lexington, and the Cincinnati-Northern Kentucky metro. Major employers with lasting hiring presence include Humana, Norton Healthcare, and Kindred Healthcare, all of which staff senior clinical project managers across trial operations, regulatory affairs, and outcomes research. Protocol management, sponsor oversight, and oncology trial coordination are consistently the most sought-after specialties in Kentucky listings. Find a role that fits below and apply directly.

Find Jobs

Overview

Open roles437+
Top employerAppalachian Regional Healthcare
Top cityLouisville, KY
Cities hiring76
Work type74% On-site
Top industryHealthcare

Showing 5 of 437+ Senior Clinical Project Manager jobs

HealthTrust Workforce Solutions
Clinical | RN: Cath Lab - Contract - Days
We won't show you this job again
HealthTrust Workforce Solutions
New 1m ago
Clinical | RN: Cath Lab - Contract - Days
HealthTrust Workforce Solutions
Maysville, Kentucky
Healthcare Administration
Nursing
Patient Services & Wellbeing
1,001-5,000

Have you applied for this role?

Caritas Care Solutions
Senior Clinical Authorization & Intake Specialist
We won't show you this job again
Caritas Care Solutions
New 1m ago
Senior Clinical Authorization & Intake Specialist
Caritas Care Solutions
Lexington, Kentucky
Clinical Support
Healthcare Administration
Human Resources
On-Site
Bachelor's degree in counseling

Have you applied for this role?

H
Lead Commercial Heating, Ventilation, and Air Conditioning Technician
We won't show you this job again
H
New 1m ago
Lead Commercial Heating, Ventilation, and Air Conditioning Technician
Hadley Energy Solutions
Louisville, Kentucky
Construction Management
Health & Safety
Skilled Trades
On-Site
EPA Refrigeration Certification

Have you applied for this role?

Humana
Lead Solutions Architect
We won't show you this job again
Humana
New 1m ago
Lead Solutions Architect
Humana
Louisville, Kentucky
Compliance & Risk
Project Management
Quality Assurance & Testing (QA Testing)
Remote (US)
Bachelor's degree
10,000+

Have you applied for this role?

Humana
Lead Entra Security Engineer
We won't show you this job again
Humana
New 1m ago
Lead Entra Security Engineer
Humana
Louisville, Kentucky
Engineering (Non-Software)
Project Management
Technical Program Management
Remote (US)
10,000+

Have you applied for this role?

See All 437+ Senior Clinical Project Manager Jobs in Kentucky

Find roles in Kentucky that match your experience and apply in just a few clicks.

Find Jobs

Senior Clinical Project Manager Jobs by City in Kentucky

Where Kentucky roles are concentrated, by current openings.

Louisville
114 jobs
Lexington
63 jobs
Hazard
17 jobs
Florence
17 jobs
Bowling Green
15 jobs
Erlanger
11 jobs
Frankfort
11 jobs
Somerset
9 jobs
Elizabethtown
9 jobs

Senior Clinical Project Manager Job Market in Kentucky

A snapshot from current Kentucky openings, updated as new roles post.

Who's Hiring

  • Appalachian Regional Healthcare
    Appalachian Regional Healthcare33
  • Baptist Health System KY & IN
    Baptist Health System KY & IN25
  • University of Kentucky
    University of Kentucky21
  • HealthTrust Workforce Solutions
    HealthTrust Workforce Solutions16
  • LifeStance Health
    LifeStance Health14

Top Industries Hiring

  • Healthcare & Medical Services120
  • Education28
  • Consulting & Professional Services19
  • Technology & Software13
  • Manufacturing9

What Kentucky Employers Look For

The qualifications that appear most often in senior clinical project manager jobs across Kentucky.

  • Bachelor's or master's degree in life sciences, nursing, or a related clinical field
  • Minimum five years of clinical research or trial management experience required
  • Project Management Professional or Clinical Research Associate certification strongly preferred
  • Demonstrated ability to manage IRB submissions, protocols, and regulatory documentation
  • Experience with ICH-GCP guidelines and FDA-regulated clinical trial environments
  • Proficiency in clinical trial management systems such as Medidata Rave or Veeva Vault

Senior Clinical Project Manager Jobs in Kentucky: Frequently Asked Questions

How do you become a senior clinical project manager in Kentucky?

The typical path begins with a bachelor's degree in a clinical or life sciences field, followed by several years in a coordinator or associate project manager role within a hospital system, contract research organization, or pharmaceutical company. Kentucky does not require a state-issued license specific to clinical project management, but employers strongly favor candidates who hold recognized credentials such as the Certified Clinical Research Professional credential from the Society of Clinical Research Associates or a PMP certification.

How much do senior clinical project managers make in Kentucky?

Senior clinical project managers in Kentucky earn a median of about $81,700 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $52,090 for the lowest 10% to over $131,670 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire senior clinical project managers in Kentucky?

Companies currently hiring senior clinical project managers in Kentucky include Appalachian Regional Healthcare, Baptist Health System KY & IN, and University of Kentucky, per current listings on Migrate Mate as of July 2026. Kentucky's concentration of large health systems, pharmaceutical manufacturers, and contract research organizations across the Louisville and Northern Kentucky corridors means consistent openings across both sponsor-side and site-side roles.

Which Kentucky cities have the most senior clinical project manager jobs?

Louisville, Lexington, and Hazard lead Kentucky for senior clinical project manager openings. Louisville dominates because of its dense concentration of health system headquarters, health insurance companies, and pharmaceutical operations, while Lexington draws demand from the University of Kentucky's academic medical center and affiliated research programs, and Northern Kentucky benefits from spillover hiring tied to the greater Cincinnati life sciences corridor.

Are there remote senior clinical project manager jobs in Kentucky?

Yes, and more than most clinical roles. About 26% of senior clinical project manager openings tied to Kentucky are remote or hybrid as of July 2026, reflecting the fact that much of the work involves protocol oversight, vendor management, and data review rather than on-site patient contact. Sponsor-side roles at pharmaceutical and biotech companies tend to offer the most remote flexibility, while site-facing positions at hospital systems generally require more in-person presence.

How can I get hired as a senior clinical project manager in Kentucky with little or no experience?

The most realistic entry path is a clinical research coordinator role at a Kentucky academic medical center or large health system, where you gain hands-on trial operations experience that employers count toward seniority. Norton Healthcare, the University of Kentucky HealthCare system, and Baptist Health all hire research coordinators and associate project managers as pipeline roles. Earning a Certified Clinical Research Coordinator credential early signals commitment and gives you a measurable edge when applying to senior positions internally or at contract research organizations operating in the state.

Where can I find and apply to senior clinical project manager jobs in Kentucky?

You can find and apply to senior clinical project manager jobs in Kentucky on Migrate Mate, which lists current Kentucky openings across health systems, pharmaceutical companies, and contract research organizations. Find roles that fit your experience and apply directly to the employers posting them.

See All 437+ Senior Clinical Project Manager Jobs in Kentucky

Find roles in Kentucky that match your experience and apply in just a few clicks.

Find Jobs