Senior Data Science Engineer Jobs in Pennsylvania

Senior Data Science Engineer jobs in Pennsylvania are in strong demand, with active hiring concentrated in financial services, healthcare systems, insurance, and defense contracting across a market that draws candidates from entry-level data scientists through staff and principal engineers. Philadelphia and Pittsburgh lead hiring volume, with Harrisburg and the Route 202 technology corridor in Montgomery County also generating consistent openings. Employers like Comcast, Independence Blue Cross, and Highmark Health have deep, lasting data science practices in the state, with in-demand specialties including machine learning engineering, NLP, and MLOps infrastructure. Find a role that fits below and apply directly.

Find Jobs

Overview

Open roles10
Top employerGettysburg College
Top cityPhiladelphia, PA
Cities hiring5
Work type50% On-site
Top industryEducation

Showing 5 of 10+ Senior Data Science Engineer jobs

Penn State University
Data Engineer – Data Architecture for Data Science & Machine Learning
We won't show you this job again
Penn State University
New 20h ago
Data Engineer – Data Architecture for Data Science & Machine Learning
Penn State University
University Park, Pennsylvania
AI (Artificial Intelligence)
Data Analytics
Data Science
$122k - $266k/yr
On-Site
Master's degree
10,000+

Have you applied for this role?

GSK
Principal Scientist, Oncology Data Science (Translational Science)
We won't show you this job again
GSK
Added 1w ago
Principal Scientist, Oncology Data Science (Translational Science)
GSK
Upper Providence, Pennsylvania
Biotech & Life Sciences
Environmental & Physical Sciences
Laboratory Research
Research & Academia
$121k - $202k/yr
On-Site
Doctoral degree in Computer Science
10,000+

Have you applied for this role?

PA Compensation Rating Bureau
Data Science Analyst (Insurance Hybrid role)
We won't show you this job again
PA Compensation Rating Bureau
Added 1mo ago
Data Science Analyst (Insurance Hybrid role)
PA Compensation Rating Bureau
Philadelphia, Pennsylvania
Business Analysis
Business Analyst
Data Analytics
Hybrid
Bachelor's degree in statistics
51-200

Have you applied for this role?

PA Compensation Rating Bureau
Data Science Analyst (Insurance- hybrid)
We won't show you this job again
PA Compensation Rating Bureau
Added 1mo ago
Data Science Analyst (Insurance- hybrid)
PA Compensation Rating Bureau
Philadelphia, Pennsylvania
Business Development
Business Strategy
Partnerships & Business Development
$75k - $85k/yr
Hybrid
Bachelor's degree in statistics
51-200

Have you applied for this role?

IntegriChain
Product Manager - Data Science (MDM / Net Revenue)
We won't show you this job again
IntegriChain
Added 1mo ago
Product Manager - Data Science (MDM / Net Revenue)
IntegriChain
Philadelphia, Pennsylvania
Business Analysis
Business Operations
Data Analytics
Revenue Operations & Enablement
Managed care
51-200

Have you applied for this role?

See All 10 Senior Data Science Engineer Jobs in Pennsylvania

Find roles in Pennsylvania that match your experience and apply in just a few clicks.

Find Jobs

Senior Data Science Engineer Jobs by City in Pennsylvania

Where Pennsylvania roles are concentrated, by current openings.

Philadelphia
5 jobs
Gettysburg
2 jobs
Pipersville
1 job
University Park
1 job
Upper Providence
1 job

Senior Data Science Engineer Job Market in Pennsylvania

A snapshot from current Pennsylvania openings, updated as new roles post.

Who's Hiring

Gettysburg College
Gettysburg College2 open roles
PA Compensation Rating Bureau
PA Compensation Rating Bureau2 open roles
GSK
GSK1 open role

Top Industries Hiring

  • Education
  • Technology & Software

What Pennsylvania Employers Look For

The qualifications that appear most often in senior data science engineer jobs across Pennsylvania.

  • Bachelor's or master's degree in computer science, statistics, or a related quantitative field
  • Five or more years of experience building and deploying machine learning models in production
  • Proficiency in Python and SQL with hands-on experience using frameworks such as TensorFlow or PyTorch
  • Experience designing MLOps pipelines and working with cloud platforms such as AWS, Azure, or GCP
  • Strong communication skills for presenting model findings and insights to non-technical stakeholders
  • Demonstrated experience with large-scale distributed data systems and tools such as Spark or Databricks

Senior Data Science Engineer Jobs in Pennsylvania: Frequently Asked Questions

How do you become a senior data science engineer in Pennsylvania?

Senior data science engineer roles in Pennsylvania do not require a state-issued license or registration, so the path runs through education and demonstrated experience. Most hiring managers expect at least a bachelor's degree in computer science, statistics, applied mathematics, or a related field, with a master's degree preferred for senior-level positions. Candidates strengthen their profile by building a portfolio of deployed ML projects, contributing to open-source work, and earning cloud certifications recognized by Pennsylvania's technology and healthcare employers.

How much do senior data science engineers make in Pennsylvania?

Senior data science engineers in Pennsylvania earn a median of about $106,850 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,340 for the lowest 10% to over $162,290 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire senior data science engineers in Pennsylvania?

Employers hiring senior data science engineers in Pennsylvania right now include Gettysburg College, PA Compensation Rating Bureau, and GSK, based on current listings on Migrate Mate as of August 2026. Pennsylvania's concentration of large health insurance carriers, regional banks, and defense primes means many of these openings sit within regulated industries where experience with sensitive or high-volume data is a competitive advantage.

Which Pennsylvania cities have the most senior data science engineer jobs?

Philadelphia, Gettysburg, and Pipersville are the Pennsylvania cities with the most senior data science engineer openings, reflecting the state's hiring geography. Philadelphia dominates because of its dense cluster of health systems, insurers, and financial institutions, while Pittsburgh draws heavily from Carnegie Mellon University's technology ecosystem and the regional presence of robotics and autonomous systems companies. Smaller suburban markets along the Route 202 corridor benefit from satellite offices of large technology employers.

Are there remote senior data science engineer jobs in Pennsylvania?

Yes, and more than most fields. Data science engineering is inherently desk-based and cloud-dependent, making it one of the more remote-compatible roles in technology. About 50% of senior data science engineer openings tied to Pennsylvania are remote or hybrid as of August 2026, reflecting broad employer acceptance of distributed work. Modeling, experimentation, and pipeline development are the tasks most commonly performed fully remotely, while stakeholder presentations and production incident response may require occasional on-site presence.

How can I get hired as a senior data science engineer in Pennsylvania with little or no experience?

The most realistic entry path is a junior or associate data scientist role at a Pennsylvania employer that runs structured development programs. Highmark Health, Comcast, and Independence Blue Cross each recruit new graduates into rotational analytics or data engineering programs where early-career hires build production experience over one to two years. Moving laterally from a data analyst or software engineering role is also common, particularly if the candidate brings strong Python skills and at least one end-to-end ML project in their portfolio. A cloud certification from AWS or Google adds a measurable credential that Pennsylvania hiring teams recognize.

Where can I find and apply to senior data science engineer jobs in Pennsylvania?

You can find and apply to senior data science engineer jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings updated in real time. Search the listings, find roles that match your experience and target city, and apply directly to the employers posting them.

See All 10 Senior Data Science Engineer Jobs in Pennsylvania

Find roles in Pennsylvania that match your experience and apply in just a few clicks.

Find Jobs