Senior Data Science Engineer Jobs in Massachusetts

Senior Data Science Engineer jobs in Massachusetts are among the most actively recruited in the country, concentrated in biotechnology, financial services, healthcare technology, and enterprise software, with demand at every level from mid-career contributors through principal and staff engineers. Boston, Cambridge, and the Route 128 corridor account for the largest share of openings, where employers like Biogen, State Street, and MathWorks maintain significant data science teams. The most sought-after specialties in Massachusetts right now are machine learning infrastructure, clinical and genomic data modeling, and large-scale MLOps. Find a role that fits below and apply directly.

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Overview

Open roles21
Top employerNovartis
Top cityBoston, MA
Cities hiring7
Work type60% On-site
Top industryBiotechnology

Showing 5 of 21+ Senior Data Science Engineer jobs

BNY
Senior Vice President, Data Science Manager
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BNY
Added 2d ago
Senior Vice President, Data Science Manager
BNY
Boston, Massachusetts
Business Development
Growth Marketing
Marketing
Master's degree in information science
10,000+

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Planet Fitness
Director, Geospatial Analytics and Data Science
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Planet Fitness
Added 2d ago
Director, Geospatial Analytics and Data Science
Planet Fitness
Boston, Massachusetts
Business Strategy
Product Management
Project Management
$200k - $240k/yr
Hybrid
Master's degree in geography
10,000+

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N
Curriculum, Data and Assessment Manager for History/Social Science
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N
Added 3d ago
Curriculum, Data and Assessment Manager for History/Social Science
New Bedford Public School District
New Bedford, Massachusetts
Corporate Training
Educational Administration
Program Management
$120k - $130k/yr
Master's degree

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AstraZeneca
Scientist, Data Science
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AstraZeneca
Added 1w ago
Scientist, Data Science
AstraZeneca
Waltham, Massachusetts
Biotech & Life Sciences
Clinical Trials & Medical Research
Research & Academia
$91k.8 - $137k.2/yr
Bachelor of Science
10,000+

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Alkermes, Inc.
Associate Director, Enterprise Data Science
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Alkermes, Inc.
Added 2w ago
Associate Director, Enterprise Data Science
Alkermes, Inc.
Waltham, Massachusetts
Business Development
Events & Tourism
Executive Leadership & C-Suite
Project Management
Bachelor's degree
1,001-5,000

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See All 21 Senior Data Science Engineer Jobs in Massachusetts

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Senior Data Science Engineer Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Boston
7 jobs
Cambridge
6 jobs
Waltham
4 jobs
Andover
1 job
Billerica
1 job
Framingham
1 job
New Bedford
1 job

Senior Data Science Engineer Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

Novartis
Novartis3 open roles
BNY
BNY1 open role
IPSEN
IPSEN1 open role

Top Industries Hiring

  • Biotechnology & Pharmaceuticals
  • Fintech
  • Technology & Software
  • Consulting & Professional Services

What Massachusetts Employers Look For

The qualifications that appear most often in senior data science engineer jobs across Massachusetts.

  • Bachelor's or master's degree in computer science, statistics, or a quantitative field
  • Five or more years of experience building and deploying production machine learning systems
  • Proficiency in Python and experience with ML frameworks such as PyTorch or TensorFlow
  • Demonstrated ability to lead cross-functional data science projects from design to deployment
  • Experience with cloud platforms such as AWS, Azure, or Google Cloud for model deployment
  • Strong communication skills for presenting technical findings to non-technical stakeholders

Senior Data Science Engineer Jobs in Massachusetts: Frequently Asked Questions

How do you become a senior data science engineer in Massachusetts?

Reaching a senior data science engineer role in Massachusetts typically requires a master's degree or equivalent in computer science, applied mathematics, or a related field, combined with several years of experience building production-grade ML systems. Massachusetts employers, particularly in biotech and finance, place significant weight on a strong portfolio of shipped models and peer-reviewed or open-source contributions. No state-issued license is required, but certifications from major cloud providers are valued in many Boston-area hiring pipelines.

How much do senior data science engineers make in Massachusetts?

Senior data science engineers in Massachusetts earn a median of about $131,750 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $81,030 for the lowest 10% to over $206,220 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire senior data science engineers in Massachusetts?

Employers hiring senior data science engineers in Massachusetts right now include Novartis, BNY, and IPSEN, based on current listings on Migrate Mate as of August 2026. Massachusetts's dense concentration of biotech, fintech, and health-tech firms means openings appear across a wide range of industries, from genomics platforms to quantitative trading groups.

Which Massachusetts cities have the most senior data science engineer jobs?

Boston, Cambridge, and Waltham have the most senior data science engineer openings in Massachusetts. Boston and Cambridge lead because of the city's anchor institutions in biotech, healthcare, and finance, while suburban Route 128 corridor cities attract openings from enterprise software and defense-technology employers who have maintained large campuses there for decades.

Are there remote senior data science engineer jobs in Massachusetts?

Yes, and more than most fields, because senior data science engineering is almost entirely desk and analytical work. About 40% of senior data science engineer openings tied to Massachusetts are remote or hybrid as of August 2026, reflecting how widely the discipline has been accepted for distributed work. Roles focused on model development and experimentation tend to be the most remote-eligible, while positions involving real-time infrastructure or regulated clinical data more often require some on-site presence.

How can I get hired as a senior data science engineer in Massachusetts with little or no experience?

The most realistic entry path is through an associate or junior data scientist role at a Massachusetts biotech or financial services company, where new graduates can contribute to production pipelines under senior supervision. Boston-area employers like Broad Institute, Liberty Mutual, and Wayfair have run structured associate data science or rotational analytics programs that accept candidates with strong academic projects in place of work history. Building a public portfolio of end-to-end ML projects on GitHub and earning a cloud-provider certification significantly improves competitiveness for these roles.

Where can I find and apply to senior data science engineer jobs in Massachusetts?

You can find and apply to senior data science engineer jobs in Massachusetts on Migrate Mate, which lists current openings across Boston, Cambridge, and the broader Massachusetts market. Find roles that fit your background and apply directly to the ones that match.

See All 21 Senior Data Science Engineer Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

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