Senior Data Science Engineer Jobs in Massachusetts
Senior Data Science Engineer jobs in Massachusetts are among the most actively recruited in the country, concentrated in biotechnology, financial services, healthcare technology, and enterprise software, with demand at every level from mid-career contributors through principal and staff engineers. Boston, Cambridge, and the Route 128 corridor account for the largest share of openings, where employers like Biogen, State Street, and MathWorks maintain significant data science teams. The most sought-after specialties in Massachusetts right now are machine learning infrastructure, clinical and genomic data modeling, and large-scale MLOps. Find a role that fits below and apply directly.
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Showing 5 of 29+ Senior Data Science Engineer jobs
This position is based in Natick, MA and is primarily on-site, with situational telework permitted only when approved.
- Real-time data collection using wearable sensors.
- Data streaming coordination includes information management rights, iCloud use, computer management and security, and data management of large data sets.
- Designs and leads research protocols evaluating human physiological responses to heat, cold, and high terrestrial altitude.
- Collects, manages, and analyzes large physiological datasets from laboratory, field, and wearable sensor studies.
- Coordinates and leads field research teams conducting studies at military installations.
- Develops technical reports, scientific manuscripts, presentations, and research documentation.
- Collaborates with investigators and research teams to translate physiological data into actionable findings and recommendations.
- Proficiency with R, SPSS, and/or MATLAB; experience with SAS and Excel is also relevant to the PWS tasks.
- Ability to coordinate and lead teams executing field studies at military installations.
- Strong scientific analysis, manuscript preparation, technical writing, and presentation capabilities.
- Ability to coordinate and lead a team of investigators to execute field studies at military bases.
- Ability to communicate (both in written and oral settings) to larger audiences.
- Ph.D. in Environmental Physiology.
- Subject matter expertise in physiological responses to heat, cold, and high terrestrial altitude.
- Experience designing and developing research protocols involving environmental extremes.
- Experience with wearable physiological sensors and real-time physiological data collection.
- Experience managing and analyzing large physiological datasets
- Experience with data cleaning, processing, statistical analysis, and interpretation of physiological data.
- Experience with exercise and metabolic testing, including maximal oxygen uptake, submaximal endurance testing, resting ventilation, and pulmonary function testing.
- Experience with phlebotomy and clinical blood gas analyzers
- Data cleaning skills in MATLAB and EXCEL to time align data points with various sensors and identify erroneous data points and outliers.
- Ability to code in MATLAB, R studio, SPSS and SAS for final data analysis and development of predictive algorithms to predict illness.
- Ability to interpret findings using subject matter expertise and literature reviews to validate the real-time models and confirm whether the findings are normal or abnormal from expected physiologic responses to a given environment.
- Subject matter expertise in the physiologic response to cold, heat and high terrestrial altitude.
- Subject matter expertise in exercise and metabolic measurements including maximal oxygen uptake, submaximal endurance testing, and resting ventilation and pulmonary function testing.
- Subject matter expertise in phlebotomy and clinical laboratory skills in running blood gas analyzers such as the NOVA Profile Plus, Radiometer, or ISTAT clinical blood analyzers.
- Travel: CONUS travel may be required based on study schedules and mission needs.
- Must obtain a favorably adjudicated Tier 3 investigation (or equivalent). At minimum, a favorable interim suitability determination must be granted before contract work begins, pending final adjudication.
- Any related additional certifications.
At Goldbelt, we value and reward our team's dedication and hard work. We provide a competitive base salary commensurate with your qualifications and experience. As an employee, you'll enjoy a comprehensive benefits package, including medical, dental, and vision insurance, a 401(k) plan with company matching, tax-deferred savings options, supplementary benefits, paid time off, and professional development opportunities.
This position is based in Natick, MA and is primarily on-site, with situational telework permitted only when approved.
- Real-time data collection using wearable sensors.
- Data streaming coordination includes information management rights, iCloud use, computer management and security, and data management of large data sets.
- Designs and leads research protocols evaluating human physiological responses to heat, cold, and high terrestrial altitude.
- Collects, manages, and analyzes large physiological datasets from laboratory, field, and wearable sensor studies.
- Coordinates and leads field research teams conducting studies at military installations.
- Develops technical reports, scientific manuscripts, presentations, and research documentation.
- Collaborates with investigators and research teams to translate physiological data into actionable findings and recommendations.
- Proficiency with R, SPSS, and/or MATLAB; experience with SAS and Excel is also relevant to the PWS tasks.
- Ability to coordinate and lead teams executing field studies at military installations.
- Strong scientific analysis, manuscript preparation, technical writing, and presentation capabilities.
- Ability to coordinate and lead a team of investigators to execute field studies at military bases.
- Ability to communicate (both in written and oral settings) to larger audiences.
- Ph.D. in Environmental Physiology.
- Subject matter expertise in physiological responses to heat, cold, and high terrestrial altitude.
- Experience designing and developing research protocols involving environmental extremes.
- Experience with wearable physiological sensors and real-time physiological data collection.
- Experience managing and analyzing large physiological datasets
- Experience with data cleaning, processing, statistical analysis, and interpretation of physiological data.
- Experience with exercise and metabolic testing, including maximal oxygen uptake, submaximal endurance testing, resting ventilation, and pulmonary function testing.
- Experience with phlebotomy and clinical blood gas analyzers
- Data cleaning skills in MATLAB and EXCEL to time align data points with various sensors and identify erroneous data points and outliers.
- Ability to code in MATLAB, R studio, SPSS and SAS for final data analysis and development of predictive algorithms to predict illness.
- Ability to interpret findings using subject matter expertise and literature reviews to validate the real-time models and confirm whether the findings are normal or abnormal from expected physiologic responses to a given environment.
- Subject matter expertise in the physiologic response to cold, heat and high terrestrial altitude.
- Subject matter expertise in exercise and metabolic measurements including maximal oxygen uptake, submaximal endurance testing, and resting ventilation and pulmonary function testing.
- Subject matter expertise in phlebotomy and clinical laboratory skills in running blood gas analyzers such as the NOVA Profile Plus, Radiometer, or ISTAT clinical blood analyzers.
- Travel: CONUS travel may be required based on study schedules and mission needs.
- Must obtain a favorably adjudicated Tier 3 investigation (or equivalent). At minimum, a favorable interim suitability determination must be granted before contract work begins, pending final adjudication.
- Any related additional certifications.
At Goldbelt, we value and reward our team's dedication and hard work. We provide a competitive base salary commensurate with your qualifications and experience. As an employee, you'll enjoy a comprehensive benefits package, including medical, dental, and vision insurance, a 401(k) plan with company matching, tax-deferred savings options, supplementary benefits, paid time off, and professional development opportunities.
See All 29 Senior Data Science Engineer Jobs in Massachusetts
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Where Massachusetts roles are concentrated, by current openings.
Senior Data Science Engineer Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Insurance
- Medical Devices
- Biotechnology & Pharmaceuticals
What Massachusetts Employers Look For
The qualifications that appear most often in senior data science engineer jobs across Massachusetts.
- Bachelor's or master's degree in computer science, statistics, or a quantitative field
- Five or more years of experience building and deploying production machine learning systems
- Proficiency in Python and experience with ML frameworks such as PyTorch or TensorFlow
- Demonstrated ability to lead cross-functional data science projects from design to deployment
- Experience with cloud platforms such as AWS, Azure, or Google Cloud for model deployment
- Strong communication skills for presenting technical findings to non-technical stakeholders
Senior Data Science Engineer Jobs in Massachusetts: Frequently Asked Questions
How do you become a senior data science engineer in Massachusetts?
Reaching a senior data science engineer role in Massachusetts typically requires a master's degree or equivalent in computer science, applied mathematics, or a related field, combined with several years of experience building production-grade ML systems. Massachusetts employers, particularly in biotech and finance, place significant weight on a strong portfolio of shipped models and peer-reviewed or open-source contributions. No state-issued license is required, but certifications from major cloud providers are valued in many Boston-area hiring pipelines.
How much do senior data science engineers make in Massachusetts?
Senior data science engineers in Massachusetts earn a median of about $131,750 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $81,030 for the lowest 10% to over $206,220 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire senior data science engineers in Massachusetts?
Employers hiring senior data science engineers in Massachusetts right now include Novartis, XPO, and Framingham State University, based on current listings on Migrate Mate as of October 2026. Massachusetts's dense concentration of biotech, fintech, and health-tech firms means openings appear across a wide range of industries, from genomics platforms to quantitative trading groups.
Which Massachusetts cities have the most senior data science engineer jobs?
Boston, Cambridge, and Waltham have the most senior data science engineer openings in Massachusetts. Boston and Cambridge lead because of the city's anchor institutions in biotech, healthcare, and finance, while suburban Route 128 corridor cities attract openings from enterprise software and defense-technology employers who have maintained large campuses there for decades.
Are there remote senior data science engineer jobs in Massachusetts?
Yes, and more than most fields, because senior data science engineering is almost entirely desk and analytical work. About 79% of senior data science engineer openings tied to Massachusetts are remote or hybrid as of October 2026, reflecting how widely the discipline has been accepted for distributed work. Roles focused on model development and experimentation tend to be the most remote-eligible, while positions involving real-time infrastructure or regulated clinical data more often require some on-site presence.
How can I get hired as a senior data science engineer in Massachusetts with little or no experience?
The most realistic entry path is through an associate or junior data scientist role at a Massachusetts biotech or financial services company, where new graduates can contribute to production pipelines under senior supervision. Boston-area employers like Broad Institute, Liberty Mutual, and Wayfair have run structured associate data science or rotational analytics programs that accept candidates with strong academic projects in place of work history. Building a public portfolio of end-to-end ML projects on GitHub and earning a cloud-provider certification significantly improves competitiveness for these roles.
Where can I find and apply to senior data science engineer jobs in Massachusetts?
You can find and apply to senior data science engineer jobs in Massachusetts on Migrate Mate, which lists current openings across Boston, Cambridge, and the broader Massachusetts market. Find roles that fit your background and apply directly to the ones that match.
See All 29 Senior Data Science Engineer Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
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