Senior IT Architect Jobs
Senior IT Architect jobs are open across financial services, healthcare, government, and enterprise technology, from mid-level to principal and distinguished architect, with specializations in cloud architecture, enterprise architecture, and cybersecurity. Find a role that fits from the openings below and apply directly.
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INTRODUCTION
McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.
What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.
ROLE SUMMARY
Ontada is an oncology data science and technology business dedicated to transforming the fight against cancer. We specialize in real-world data and evidence generation that accelerates life science research, clinical technologies that support community providers with precise care, and provider engagement channels that enable education and insights.
We are hiring an IT Architect to define and drive cloud-native integration architecture across Ontada products and partner ecosystems. This role owns solution and platform architecture for API-led connectivity, event-driven integration, and secure data exchange—ensuring our systems are scalable, reliable, observable, and straightforward to evolve. Familiarity with healthcare interoperability standards (HL7/FHIR, including SMART on FHIR) is a plus for certain partner pathways, but the primary focus is strong enterprise-architecture fundamentals applied to modern cloud-native integration models.
Success in this role is measured by the clarity and adoption of your reference architectures and standards, the reliability and scalability of the integration ecosystem you enable, and your ability to influence decisions across multiple initiatives while mentoring and elevating engineering teams. Familiarity with AI/ML and NLP capabilities used in products (e.g., LLM-enabled workflows, retrieval patterns, evaluation, and governance) is a plus as Ontada expands intelligent experiences, but is not the core requirement.
TECHNICAL ENVIRONMENT
Cloud-Native Integration: API-led connectivity, event-driven architecture, pub/sub, schema management, idempotency, retries, backpressure
APIs: RESTful services, OpenAPI/Swagger, API gateways, versioning and contract-first design
Messaging: Kafka (or equivalent), queues/streams, event schema design
Platform Patterns: Microservices, containerization (Docker), service discovery, configuration management; service mesh (where applicable)
Data & Performance: Oracle and relational databases; Redis (caching); Elasticsearch; analytics/pipelines (e.g., Databricks)
Interoperability (nice to have): HL7v2, FHIR (R4+), SMART on FHIR, OAuth2/OIDC, C-CDA
Observability: Logging, metrics, distributed tracing (e.g., Dynatrace)
Cloud & Platforms: Azure, AWS, GCP, Cloud Foundry
Engineering Practices: CI/CD, automated testing, code reviews, architecture documentation
KEY RESPONSIBILITIES
Architecture Leadership & Strategy
- Drive architecture for interoperability and integration capabilities across systems, services, and product offerings.
- Partner with Product Owners, Sales, Business Analysts, Quality Assurance, and Project Management to translate functional and non-functional requirements into target architectures and delivery plans.
- Define architecture standards, reference implementations, and guardrails for APIs, integration patterns, security, and operational readiness.
- Evaluate solution options and drive alignment across stakeholders; communicate tradeoffs, risks, and recommendations to technical and non-technical audiences.
- Provide technical guidance to coach, motivate, and develop engineers and architects.
Cloud-Native Integration Architecture
- Define and govern integration reference architectures across APIs, events, and asynchronous workflows (request/response, pub/sub, choreography vs. orchestration).
- Establish platform patterns and guardrails for API gateways, service-to-service communication, schema/version management, and contract testing.
- Design for resiliency and performance using proven patterns (timeouts, retries, circuit breakers, bulkheads, idempotency, caching) and align to SLOs/SLAs.
- Guide event-driven integration (e.g., Kafka or equivalent) with well-defined event schemas, lifecycle management, and operational controls.
- Collaborate with security and platform teams to ensure secure-by-default integration approaches (OAuth2/OIDC, least privilege, secrets management, threat modeling).
Healthcare Interoperability (Optional) & Partner Integrations
- When applicable, drive design for healthcare data exchange leveraging HL7v2 and/or FHIR (R4+), including SMART on FHIR, to enable integrations with EMRs and partner systems.
- Partner with domain SMEs and external stakeholders to define interoperability expectations (security, conformance, and onboarding) and ensure integrations are scalable and supportable.
- Define API contracts, versioning strategy, and error taxonomy to enable predictable integrations for internal and external consumers.
- Partner with engineering teams to implement and evolve reusable integration components, adapters, and accelerators that reduce time-to-integrate.
Operational Excellence & Production Ownership
- Collaborate with engineering in release, sprint, and project planning to ensure delivery commitments are tracked and met across the SDLC.
- Demonstrate strong architectural ownership in production operations to address customer needs for support, issue analysis, enhancements, and corrective actions.
- Evolve software systems, infrastructure, and architecture to support growth, SLAs, availability, and continued operation.
- Drive operational readiness practices including observability, runbooks, incident response, and post-incident improvements.
- Resolve technical problems, issues, and escalations across delivery teams and project activities.
AI Enablement (Preferred)
- Partner with product and engineering teams to identify and deliver AI-enabled capabilities, from discovery and design through deployment, monitoring, and continuous improvement.
- Guide architecture patterns for integrating model services into cloud-native systems (APIs, events, data pipelines) with appropriate security, privacy, and compliance controls.
- Promote MLOps/LLMOps practices (versioning, CI/CD, automated testing, observability, rollback) and responsible AI governance.
- Collaborate on evaluation approaches to ensure AI features are reliable and safe for production use.
MINIMUM REQUIREMENT
Degree or equivalent and typically requires 7+ years of relevant experience.
Education
Bachelor’s degree in computer science, Software Engineering, Information Systems, or equivalent practical experience.
CRITICAL SKILLS
- 7+ years of software engineering experience, including 4+ years in architecture (solution, platform, or enterprise) with ownership across multiple systems.
- Strong enterprise integration architecture skills across REST APIs, event-driven messaging, and secure data exchange patterns.
- Strong technical fundamentals in cloud-native architecture (microservices, containers, resiliency patterns, observability) on Azure, AWS, or GCP.
- Experience designing and operating large-scale, multi-tenant services with reliability, scalability, and security best practices.
- Ability to drive cross-functional technical decisions, mentor engineers/architects, and communicate clearly through documentation and design reviews.
- Strong communication and stakeholder-management skills, with a track record of influencing cross-team decisions through documentation and design reviews.
- Nice to have: familiarity with HL7/FHIR and/or willingness to learn quickly as needed for partner integrations.
PREFERRED SKILLS
- Optional/nice to have: hands-on experience with FHIR (profiles, implementation guides, SMART on FHIR) and/or HL7v2, including conformance and integration testing.
- Experience integrating with multiple EMRs and partner ecosystems; familiarity with common healthcare workflows and data exchange constraints.
- Hands-on experience with microservices frameworks (e.g., Spring or equivalent) and API management practices.
- Experience with messaging and integration platforms (Kafka, service bus/queues, stream processing) and caching technologies (e.g., Redis).
- Experience with platform engineering patterns such as service mesh, policy-as-code, and automated architecture validation in CI/CD.
- Experience with observability platforms (e.g., Dynatrace) and production operations best practices.
- AI/ML product delivery experience (LLM-enabled workflows, evaluation, and responsible AI governance).
- Experience with Elasticsearch and/or analytics platforms (e.g., Databricks).
WHAT SUCCESS LOOKS LIKE
At 6 Months
- You have established and socialized a target-state cloud-native integration architecture, with clear standards for APIs, events, resiliency, and security.
- You have delivered at least one end-to-end initiative (design through production) for a key integration capability (e.g., event streaming, API modernization, partner onboarding accelerator).
- Teams are adopting your reference patterns and documentation with reduced integration friction and faster delivery.
- You are actively supporting production operations through improved observability, incident learnings, and reliability improvements.
At 12 Months
- You own and continuously improve the integration architecture across multiple products and partner pathways, with measurable gains in reliability, scalability, and onboarding speed.
- You have matured governance for integration assets (API standards, event schemas, implementation guides where applicable, and conformance testing) and created a repeatable delivery playbook across the SDLC.
- You are a trusted technical leader influencing roadmaps, investment decisions, and cross-team alignment.
- You have helped teams incorporate intelligent capabilities responsibly (where applicable) through clear evaluation, monitoring, and risk controls.
We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.
Our Base Pay Range for this position
$133,100 - $221,900
McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:
McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.
McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.
McKesson job postings are posted on our career site: careers.mckesson.com.
McKesson is an Equal Opportunity Employer
McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.
McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com or (Canada) Accessibility@mckesson.ca. Resumes or CVs submitted to this email box will not be accepted.
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Find Senior IT Architect JobsSenior IT Architect Job Market
A snapshot from current openings nationwide, updated as new roles post.
Who's Hiring
- Boston Consulting36

- Transaction Network Services (TNS)26

- Thermo Fisher Scientific6

- NVIDIA5

- Abbott3

Top Industries Hiring
- Consulting & Professional Services53
- Technology & Software33
- Telecommunications26
- Biotechnology & Pharmaceuticals8
- Food & Beverage4
What Employers Look For
The qualifications that appear most often in senior IT architect jobs.
- Bachelor's degree in computer science, information systems, or a related engineering field
- Ten or more years of progressive IT experience with at least five in an architecture role
- Proficiency in cloud platforms such as AWS, Microsoft Azure, or Google Cloud
- TOGAF certification or demonstrated experience applying an enterprise architecture framework
- Experience designing solutions that meet security, compliance, and regulatory requirements
- Strong stakeholder communication skills including presenting architecture decisions to executive leadership
Tips for Your Senior IT Architect Job Search
Tailor your resume to architecture frameworks
Hiring managers scan for TOGAF, Zachman, or SABSA on senior it architect resumes before reading anything else. Name the specific frameworks you've applied, the context you applied them in, and the outcome. Generic mentions get filtered out.
Quantify scope not just technology
Senior it architect roles demand proof of scale. Replace tool lists with statements about the number of systems integrated, the size of the environments you designed for, and the business capabilities your architecture enabled. Scope signals seniority faster than any certification.
Filter openings by domain before applying
Cloud, data, security, and enterprise architecture are distinct hiring tracks. Read each posting carefully to confirm the domain matches your depth. Applying broadly across tracks without adjusting your materials signals a lack of focus to technical hiring panels.
Apply early to roles that fit
Migrate Mate lists senior it architect openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare a portfolio of architecture artifacts
Interviewers at the senior level routinely ask candidates to walk through a real architecture decision. Bring sanitized diagrams, an architecture decision record, or a reference architecture you designed. Talking abstractly about past work is the single most common reason senior candidates stall in final rounds.
Negotiate total compensation not just base
Senior it architect offers frequently include signing bonuses, equity, or training budgets that vary more than base pay does. Ask for the full offer in writing before negotiating and address each component separately rather than accepting a packaged counter that obscures tradeoffs.
Senior IT Architect Jobs: Frequently Asked Questions
Which companies are hiring the most senior it architects?
The companies hiring the most senior it architects right now include Boston Consulting, Transaction Network Services (TNS), and Thermo Fisher Scientific, with the largest share of openings in Texas, California, and Illinois, based on current listings on Migrate Mate as of June 2026. Demand is concentrated in financial services, federal contracting, and large enterprise technology organizations.
How many senior it architect jobs are remote?
About 26% of senior it architect openings are fully remote or hybrid as of June 2026, making it one of the more flexible senior technical roles in the market. Cloud architecture and enterprise architecture sub-specializations tend to have the highest share of remote-eligible postings, while infrastructure and data center roles lean more toward on-site or hybrid.
How do you become a senior it architect?
Most senior it architects move through a progression from systems administrator, engineer, or developer into a solutions architect role, then into senior or enterprise architecture. Earning a cloud certification on AWS, Azure, or Google Cloud is a practical first step. Adding a TOGAF certification signals fluency in enterprise architecture governance. Building a portfolio of architecture decisions and stakeholder presentations matters as much as credentials when competing for senior roles.
Can you get hired as a senior it architect without direct architecture experience?
Candidates who have led technical design work, owned system integration decisions, or driven platform migrations often qualify for senior it architect roles even without the exact title. Employers care more about demonstrated architectural thinking than job title history. Framing your resume around design decisions, tradeoffs you evaluated, and outcomes you delivered is more effective than waiting until your title matches.
What does the senior it architect interview process look like?
The process typically starts with a recruiter screen focused on domain depth and framework experience, followed by a technical interview where you walk through a past architecture you designed. Most employers then add a whiteboard or case-study round where you design a system live in front of the panel. Final rounds at larger organizations include a presentation to stakeholders or a formal architecture review with the hiring team.
Where can I find and apply to senior it architect jobs?
You can find and apply to senior it architect jobs on Migrate Mate, which lists current openings from across the United States. Search the listings to find roles that match your domain and experience level, then apply directly to each one that fits.
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