Senior Researcher Jobs in Missouri
Senior Researcher jobs in Missouri are concentrated in academic research institutions, pharmaceutical and life sciences, and public policy and social science sectors, with demand running from mid-career specialists to principal-level investigators. The heaviest hiring is in St. Louis, Kansas City, and Columbia, anchored by employers like Washington University in St. Louis, the University of Missouri system, and Pfizer's Missouri operations. The most in-demand specialties are clinical and translational research, behavioral and social science, and data-driven policy research. Find a role that fits below and apply directly.
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Location
SAINT LOUIS, MO 63110Scheduled Hours
40Position Summary
The Santi lab is seeking a motivated and detail-oriented Senior Research Technician to join a laboratory investigating sperm physiology, biomarkers of male infertility, and the development of novel contraceptive approaches.Our research focuses on understanding the cellular and molecular mechanisms that regulate sperm function and fertility. The successful candidate will participate in studies examining sperm membrane physiology, intracellular calcium signaling, membrane potential, sperm motility, infertility-associated biomarkers, and the effects of candidate compounds on sperm function.
The technician will be trained in fluorescence-based assays using voltage- and calcium-sensitive fluorescent indicators, plate-reader measurements, quantitative sperm motility assays, and data-analysis approaches. The position will also involve evaluating candidate molecules and pharmacological interventions for their potential effects on sperm function and their potential utility in the development of novel contraceptive strategies.
This position is particularly suited to an individual who enjoys hands-on laboratory research, is highly attentive to experimental detail, has strong quantitative skills, and is interested in translating basic discoveries in reproductive physiology into approaches relevant to infertility diagnosis and contraceptive development.
Performs independently complex research studies, experiments and assays.
Job Description
Primary Duties & Responsibilities:
Additional information about the lab can be found at https://reproductivesciences.wustl.edu/laboratories/santi-lab/ .
- Performs complex analysis/projects according to research protocols, explaining methods and procedures to other technicians.
- Enters data and maintains current data files on research projects. Monitors data to ensure consistent quality.
- May perform preliminary statistical analysis of data.
- Prepares figures, tables, and summaries for laboratory meetings, presentations, manuscripts, and grant-related activities.
- Reads and discusses relevant scientific literature.
- Troubleshoots experimental procedures and contributes to improving assay reproducibility.
- Assures compliance with established safety procedures and maintains required documentation on laboratory and specimen conditions.
- Ensures lab conditions and equipment are properly cleaned and maintained in accordance with established procedures.
- Assists in the training and development of technicians, acting as a group leader. Performs other duties as assigned.
Working Conditions:
- Works in a laboratory environment with potential exposure to biological and chemical hazards.
- Must be physically able to wear protective equipment and to provide standard care to research animals.
Required Qualifications
Education:
Master’s degree or combination of education and/or experience may substitute for minimum education.
Certifications /Professional Licenses :
Work Experience:
Skills:
Driver's License:
More About This Job
Preferred Qualifications:
- Research experience involving sperm biology, reproductive physiology, male infertility, cellular physiology, pharmacology, or fluorescence-based assays.
- Experience with GraphPad Prism, R, Python, MATLAB, or comparable data-analysis software.
Preferred Qualifications
Education:
No additional education unless stated elsewhere in the job posting.
Certifications /Professional Licenses :
Work Experience:
Skills:
Communication, Laboratory Instrumentation, Recordkeeping, Software Program, Working IndependentlyGrade
R08-HSalary Range
$18.77 - $31.94 / Hourly The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.Questions
For frequently asked questions about the application process, please refer to our External Applicant FAQ .
Accommodation
If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.Benefits Statement
Personal
Up to 22 days of vacation, 10 recognized holidays, and sick time.
Competitive health insurance packages with priority appointments and lower copays/coinsurance.
Take advantage of our free Metro transit U-Pass for eligible employees.
WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness
Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
Family
We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.
WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/
EEO Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity or shared ancestry, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information. As a federal contractor, the university maintains affirmative action programs to implement its equal employment opportunity policy for individuals with disabilities and protected veterans, in accordance with Section 503 of the Rehabilitation Act of 1973, as amended, and the Vietnam Era Veterans’ Readjustment Assistance Act of 1974 (VEVRAA), as amended.See All 15 Senior Researcher Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Senior Researcher JobsSenior Researcher Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Senior Researcher Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Banking & Financial Services
- Investment & Asset Management
What Missouri Employers Look For
The qualifications that appear most often in senior researcher jobs across Missouri.
- Master's or doctoral degree in a relevant field such as life sciences, social sciences, or public policy
- Minimum five years of research experience with demonstrated project leadership or independent inquiry
- Proficiency in quantitative or qualitative research methods appropriate to the discipline
- Experience managing IRB protocols, grant applications, or federally funded research projects
- Strong record of peer-reviewed publication, technical reporting, or policy documentation
- Familiarity with Missouri research compliance standards and institutional review processes
Senior Researcher Jobs in Missouri: Frequently Asked Questions
How do you become a senior researcher in Missouri?
Most senior researcher positions in Missouri require a master's degree at minimum, with a doctorate preferred for roles at universities and research hospitals. Missouri does not issue a general state license for researchers, but those working in clinical settings must comply with institutional credentialing and IRB registration requirements set by their employing institution. Employers at Missouri universities and health systems typically require demonstrated experience managing independent research projects and a record of publication or funded inquiry before granting a senior designation.
Which companies hire senior researchers in Missouri?
Employers hiring senior researchers in Missouri right now include Washington University in St. Louis, University of Missouri, and University of Missouri-Kansas City, based on current listings on Migrate Mate as of November 2026. Missouri's concentration of research universities, health systems, and pharmaceutical operations makes it one of the more consistent markets in the Midwest for senior-level research talent.
Which Missouri cities have the most senior researcher jobs?
The cities with the most senior researcher openings in Missouri are Kansas City, Columbia, and St. Louis. St. Louis leads because of its dense cluster of research universities, academic medical centers, and life sciences companies, while Kansas City draws demand from health policy organizations and applied research firms, and Columbia's volume is driven by the University of Missouri system's research programs.
Are there remote senior researcher jobs in Missouri?
Yes, and more than many professional fields, particularly for researchers in social sciences, public policy, and data analysis whose work is largely desk-based. About 80% of senior researcher openings tied to Missouri are remote or hybrid as of November 2026, reflecting how much research work can be conducted off-site. Laboratory, clinical, and fieldwork-intensive roles remain predominantly on-site, while literature review, data modeling, and grant writing positions are the most likely to appear as fully remote.
How can I get hired as a senior researcher in Missouri with little or no experience?
The most realistic entry path is joining a university research lab or institute as a research assistant or coordinator while completing or just finishing a graduate degree. Washington University in St. Louis, the University of Missouri system, and Saint Louis University regularly post entry-level and postdoctoral research positions that build toward senior roles. Moving laterally from a data analyst, clinical coordinator, or program evaluator position is also a recognized path. A completed thesis, published poster, or IRB-certified study gives candidates a concrete edge when applying at Missouri research institutions.
Where can I find and apply to senior researcher jobs in Missouri?
You can find and apply to senior researcher jobs in Missouri on Migrate Mate, which lists current Missouri openings across industries and hiring organizations. Find roles that fit your background and apply directly through the listings.
See All 15 Senior Researcher Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
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