Biotech & Pharma STEM OPT Jobs in Massachusetts
Massachusetts is one of the top states for biotech and pharma F-1 STEM OPT sponsorship, with major employers like Moderna, Biogen, and Vertex Pharmaceuticals concentrated in the Greater Boston and Cambridge corridor. The state's dense cluster of research institutions and life sciences companies creates consistent demand for STEM-designated roles that qualify for the 24-month OPT extension.
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LI#-Hybrid
Location: Cambridge (USA)
We are seeking an enthusiastic and motivated PK Sciences representative to lead the development and use of artificial intelligence (AI) enabled strategies to transform clinical pharmacology support of transformative new medicines. The successful candidate will offer insight into the development of AI-based applications to support strategic, scientific and operational leadership. They would focus on developing AI-based solutions to enhance the automation, innovation and acceleration of PKS/clinical pharmacology deliverables across the organization. Our unique organizational structure enables colleagues to work seamlessly in the translational and/or clinical space, offering opportunities for development and bench-to-bedside-to-bench translation. Experience in late discovery into clinical development is preferred. The scope of the role potentially includes small molecules, biologics/therapeutic proteins, antibody drug-conjugates, radioligand therapies and/or cell therapies across major therapeutic areas in Novartis, including oncology, immunology, cardiovascular renal metabolism, neuroscience, and global health. This position drives close interdisciplinary collaboration among the PK Science disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), and Operations through PK science sub-teams to achieve a holistic and integrative perspective of the ADME/clinical pharmacology properties of candidates and drugs. Collaborate effectively with broader, cross disciplinary project teams to ensure PKS strategies are well integrated into project plans and scientific discussions.
About the Role
Key responsibilities:
- Brings strong AI and digital fluency, using enterprise tools to further strategic, scientific and operational leadership in clinical pharmacology
- Identifies, develops and implements high-value use cases where AI can materially improve clinical pharmacology planning, analyses and decision quality.
- Represent the PK Sciences function in project teams, interactions with stakeholders within the organization and interactions with regulatory agencies, as appropriate
- Proactively contributes to developing drug candidates across Research Development and Commercial continuum, providing expert pharmacokinetic / drug metabolism and clinical pharmacology input
- Work with teams to use AI to accelerate and enhance the understanding of nonclinical and clinical PK/PD relationships and development dosing strategies and predictions
- Champion the use of AI to accelerate and enhance the provision of dosage, and PK/PD components of study protocols, reports, project summaries and development plans, and author pharmacokinetic/clinical pharmacology/biopharmaceutics sections of IND/IMPDs and NDA/BLAs as well as prepare appropriate responses to Health Authority questions
- Drives close interdisciplinary collaboration among the PK Science disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), through PK science sub-teams.
- Works in close collaboration with clinicians and clinical development colleagues to integrate PKS insights into study design, data interpretation, and project decision-making
- Models the use of Artificial intelligence (AI) / Machine Learning (ML) approaches to enable model guided molecular design, preclinical and clinical data automation, and authoring regulatory documents.
This role reports to a Therapeutic Area head within PK Sciences within Translational Medicine (TM) in Biomedical Research. PKS is a global organization situated within Translational Medicine (TM), the clinical research arm of Biomedical Research within Novartis. PK Sciences plays a pivotal role in bringing innovative medicines to patients, by building on research advances to develop new therapies, bridging drug discovery and clinical application. PK Science is an enterprise-wide organization, working across both Biomedical Research and the Development organizations to advance the scientific knowledge of pharmacokinetics, metabolism and clinical pharmacology.
Essential Requirements
- Ph.D. / Pharm.D. with relevant experience in clinical pharmacology, drug metabolism and pharmacokinetics or a related background.
- A minimum of 0-2 years of experience in drug discovery and/or development in a relevant environment (academia, CRO, biotech or Pharma).
- 2+ years of experience preferably in a lead role overseeing ADME/DMPK project strategy in clinical development, or in AI strategy, to be considered for Principal Scientist II. 4+ years of experience to be considered for Senior Principal Scientist.
- Extensive and in-depth knowledge of pharmacokinetics including, drug metabolism and PK/PD evaluation, experience in working in project teams (preferably global) as well as sound awareness of recent developments in drug development and regulatory sciences.
- Exposure to working in a cross-functional, matrixed, project-team environment.
- Strong oral and written communication skills.
Desirable Requirements
- Hands-on project experience with Artificial intelligence (AI) approaches and examples of applying AI to clinical pharmacology topics is a plus
This is a dual posting. The final level & title of the offer role would be determined by the hiring team based on the skills, experience & capabilities required to perform the role at the level the role has been offered.
The salary for this position is expected to range between:
Principal Scientist II: $119,700 and $222,300 per year.
Senior Principal Scientist: $138,600 and $257,400 per year.
The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click here.
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?
Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.
Read our handbook (PDF 30 MB)
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Division
Biomedical Research
Business Unit
Research
Location
USA
State
Massachusetts
Site
Cambridge (USA)
Company / Legal Entity
U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.
Functional Area
Research & Development
Job Type
Full time
Employment Type
Regular
Shift Work
No
Summary
LI#-Hybrid
Location: Cambridge (USA)
We are seeking an enthusiastic and motivated PK Sciences representative to lead the development and use of artificial intelligence (AI) enabled strategies to transform clinical pharmacology support of transformative new medicines. The successful candidate will offer insight into the development of AI-based applications to support strategic, scientific and operational leadership. They would focus on developing AI-based solutions to enhance the automation, innovation and acceleration of PKS/clinical pharmacology deliverables across the organization. Our unique organizational structure enables colleagues to work seamlessly in the translational and/or clinical space, offering opportunities for development and bench-to-bedside-to-bench translation. Experience in late discovery into clinical development is preferred. The scope of the role potentially includes small molecules, biologics/therapeutic proteins, antibody drug-conjugates, radioligand therapies and/or cell therapies across major therapeutic areas in Novartis, including oncology, immunology, cardiovascular renal metabolism, neuroscience, and global health. This position drives close interdisciplinary collaboration among the PK Science disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), and Operations through PK science sub-teams to achieve a holistic and integrative perspective of the ADME/clinical pharmacology properties of candidates and drugs. Collaborate effectively with broader, cross disciplinary project teams to ensure PKS strategies are well integrated into project plans and scientific discussions.
About the Role
Key responsibilities:
- Brings strong AI and digital fluency, using enterprise tools to further strategic, scientific and operational leadership in clinical pharmacology
- Identifies, develops and implements high-value use cases where AI can materially improve clinical pharmacology planning, analyses and decision quality.
- Represent the PK Sciences function in project teams, interactions with stakeholders within the organization and interactions with regulatory agencies, as appropriate
- Proactively contributes to developing drug candidates across Research Development and Commercial continuum, providing expert pharmacokinetic / drug metabolism and clinical pharmacology input
- Work with teams to use AI to accelerate and enhance the understanding of nonclinical and clinical PK/PD relationships and development dosing strategies and predictions
- Champion the use of AI to accelerate and enhance the provision of dosage, and PK/PD components of study protocols, reports, project summaries and development plans, and author pharmacokinetic/clinical pharmacology/biopharmaceutics sections of IND/IMPDs and NDA/BLAs as well as prepare appropriate responses to Health Authority questions
- Drives close interdisciplinary collaboration among the PK Science disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), through PK science sub-teams.
- Works in close collaboration with clinicians and clinical development colleagues to integrate PKS insights into study design, data interpretation, and project decision-making
- Models the use of Artificial intelligence (AI) / Machine Learning (ML) approaches to enable model guided molecular design, preclinical and clinical data automation, and authoring regulatory documents.
This role reports to a Therapeutic Area head within PK Sciences within Translational Medicine (TM) in Biomedical Research. PKS is a global organization situated within Translational Medicine (TM), the clinical research arm of Biomedical Research within Novartis. PK Sciences plays a pivotal role in bringing innovative medicines to patients, by building on research advances to develop new therapies, bridging drug discovery and clinical application. PK Science is an enterprise-wide organization, working across both Biomedical Research and the Development organizations to advance the scientific knowledge of pharmacokinetics, metabolism and clinical pharmacology.
Essential Requirements
- Ph.D. / Pharm.D. with relevant experience in clinical pharmacology, drug metabolism and pharmacokinetics or a related background.
- A minimum of 0-2 years of experience in drug discovery and/or development in a relevant environment (academia, CRO, biotech or Pharma).
- 2+ years of experience preferably in a lead role overseeing ADME/DMPK project strategy in clinical development, or in AI strategy, to be considered for Principal Scientist II. 4+ years of experience to be considered for Senior Principal Scientist.
- Extensive and in-depth knowledge of pharmacokinetics including, drug metabolism and PK/PD evaluation, experience in working in project teams (preferably global) as well as sound awareness of recent developments in drug development and regulatory sciences.
- Exposure to working in a cross-functional, matrixed, project-team environment.
- Strong oral and written communication skills.
Desirable Requirements
- Hands-on project experience with Artificial intelligence (AI) approaches and examples of applying AI to clinical pharmacology topics is a plus
This is a dual posting. The final level & title of the offer role would be determined by the hiring team based on the skills, experience & capabilities required to perform the role at the level the role has been offered.
The salary for this position is expected to range between:
Principal Scientist II: $119,700 and $222,300 per year.
Senior Principal Scientist: $138,600 and $257,400 per year.
The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click here.
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?
Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.
Read our handbook (PDF 30 MB)
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Division
Biomedical Research
Business Unit
Research
Location
USA
State
Massachusetts
Site
Cambridge (USA)
Company / Legal Entity
U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.
Functional Area
Research & Development
Job Type
Full time
Employment Type
Regular
Shift Work
No
STEM OPT Biotech & Pharma Job Roles in Massachusetts
See all 307+ Biotech & Pharma STEM OPT Jobs in Massachusetts
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Search Biotech & Pharma Jobs in MassachusettsBiotech & Pharma STEM OPT Sponsorship Jobs in Massachusetts: Frequently Asked Questions
Which biotech & pharma companies sponsor F-1 STEM OPT visas in Massachusetts?
Massachusetts is home to a high concentration of biotech and pharma employers with documented F-1 STEM OPT sponsorship activity, including Moderna, Biogen, Vertex Pharmaceuticals, Sanofi, AstraZeneca, and Takeda, many of which operate large research and development campuses in Cambridge, Boston, and Waltham. These companies regularly hire for STEM-designated roles in computational biology, clinical research, and drug development.
Which cities in Massachusetts have the most biotech & pharma F-1 STEM OPT sponsorship jobs?
Cambridge and Boston together form the core of Massachusetts biotech hiring, anchored by Kendall Square, which hosts dozens of life sciences companies and CROs. Waltham, Lexington, and Marlborough have significant pharma manufacturing and R&D operations as well. Worcester is a growing hub tied to UMass Medical School and regional biotech startups, making it worth including in your search.
What types of biotech & pharma roles typically qualify for F-1 STEM OPT sponsorship?
Roles that qualify for STEM OPT are those classified under STEM-designated degree fields by USCIS. In biotech and pharma, this commonly includes bioinformatics analyst, computational biologist, bioprocess engineer, research scientist, data scientist in clinical trials, and regulatory affairs specialist with a science degree. The position must be directly related to your qualifying STEM degree, and your employer must be enrolled in E-Verify.
How do I find biotech & pharma F-1 STEM OPT sponsorship jobs in Massachusetts?
Migrate Mate is built specifically for F-1 STEM OPT job seekers and lets you filter biotech and pharma roles in Massachusetts by visa sponsorship type, including STEM OPT. Rather than sorting through general job postings, Migrate Mate surfaces employers with verified sponsorship history in the life sciences sector, so you can focus your applications on companies already set up to support your OPT authorization in Massachusetts.
Are there any state-specific or industry-specific considerations for F-1 STEM OPT sponsorship in Massachusetts biotech and pharma?
Massachusetts employers in biotech and pharma are generally familiar with STEM OPT requirements, including the E-Verify enrollment mandate and the 24-month extension timeline, partly because the state's heavy reliance on international STEM talent from MIT, Harvard, and Boston University has made sponsorship a standard part of hiring. However, roles at federally funded research labs or certain government-contracted facilities may have citizenship or security clearance requirements that can limit F-1 eligibility.