Nonprofit STEM OPT Jobs in Massachusetts
F-1 STEM OPT sponsorship in Massachusetts nonprofits spans research hospitals like Dana-Farber Cancer Institute and Mass General Brigham, public health organizations, and education-focused nonprofits concentrated in Boston, Cambridge, and Worcester. Many roles in data analysis, biostatistics, health informatics, and program evaluation qualify for STEM OPT designation, making the state a strong market for international students seeking nonprofit work authorization.
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Get Access To All JobsTitle: Post Doctoral Res Assoc U M - Upi Lab
Executive Area: Academic Affairs
College/School/MBU: College of Natural Sciences
Department: Veterinary & Animal Sciences
Work Location: Amherst
Schedule: Full Time
Work Arrangement: Onsite
Job Summary
The Upi Lab in the Department of Veterinary and Animal Sciences (VASCI) at the University of Massachusetts Amherst is seeking a highly motivated Postdoctoral Research Fellow to investigate immunometabolic regulation of tissue-resident immune cells in mucosal tissues. Research in the laboratory focuses on understanding how nutrient sensing, metabolism, and immune-epithelial interactions shape chronic inflammatory diseases, colorectal cancer, HIV-associated gut dysfunction, and reproductive mucosal health. The successful candidate will develop independent research projects while contributing to collaborative and translational studies utilizing human tissues, mouse models, organoids, single-cell genomics, and advanced imaging approaches.
Essential Functions
Research projects in the laboratory focus on, immunometabolic regulation of tissue-resident T cells, chronic inflammatory diseases of the gastrointestinal and reproductive tracts, early-onset colorectal cancer and HIV-associated mucosal dysfunction.
Nutrient sensing and immune adaptation at barrier tissues.
Design, conduct, and analyze experiments related to mucosal immunology and immunometabolism.
Develop independent research projects aligned with the laboratory's mission.
Perform studies using mouse models, organoids, human tissue samples, flow cytometry, microscopy, and molecular biology techniques.
Participate in collaborative projects across UMass and external institutions.
Prepare manuscripts for publication in high-impact journals.
Present findings at national and international scientific meetings.
Contribute to grant applications and fellowship submissions.
Mentor graduate students, undergraduate researchers, and technicians.
Assist with establishing laboratory protocols and research infrastructure.
Contribute to a collaborative and inclusive laboratory environment.
Other Functions
Work collaboratively and effectively to promote teamwork, equality and inclusiveness.
Work in partnership with colleagues within the CNS community and across the campus to support the Dean’s strategic priorities.
Perform other duties as assigned in support of the mission and goals of the College of Natural Sciences.
Minimum Qualifications
PhD, MD, or equivalent doctoral degree in Immunology, Cell Biology, Cancer Biology, Molecular Biology, Bioengineering, or a related field.
Demonstrated publication record in peer-reviewed journals.
Experience in at least one of the following areas: immunology, metabolism, cancer biology, mucosal biology, stem cell biology, microbiology, or computational biology.
Strong written and oral communication skills.
Ability to work both independently and collaboratively.
Preferred Qualifications
Experience with flow cytometry, single-cell RNA sequencing, spatial biology, metabolomics, organoid culture, or animal models.
Experience analyzing transcriptomic or other high-dimensional datasets.
Interest in pursuing an academic, biotechnology, or translational research career.
Prior experience mentoring trainees.
Additional Details
This is a temporary, grant funded position.
At UMass Amherst and in CNS, we strive to be a community where every individual feels a sense of belonging, where every individual is included, and where every individual is valued. These values and goals are reflected in the College of Natural Sciences’ Inclusive Excellence framework and in the UMass Amherst’s For the Common Good: 2024–2034 Strategic Plan.
Working Conditions
Work is performed in a laboratory or healthcare setting and may involve exposure to chemicals or infectious diseases. Requires standing for extended periods of time and/or use of protective gear.
Work Schedule and Work Arrangement
Monday – Friday 8:30am – 5:00pm and may have to be altered occasionally to accommodate timing of experiments and other factors.
Salary Information
Salary minimum is determined by collective bargaining agreement based on years of experience. Salary may exceed the floor and will be determined by the PI (final salary will be stated in offer letter).
Current salary floors based on 100% time, 40 hours/week:
0-2 years $62,838
3-4 years $66,287
5+ years $71,033
Special Instructions for Applicants
Along with the application, please submit a resume and a cover letter. References will be checked at the finalist stage. Please be prepared to provide contact information for three (3) professional references. Applications will be reviewed on a continuous basis until the position is filled. Early submissions are encouraged.
This position will remain open for the time period required by any applicable collective bargaining agreement and will continue until a suitable candidate pool is identified. Interested applicants are strongly encouraged to apply early.
Title: Post Doctoral Res Assoc U M - Upi Lab
Executive Area: Academic Affairs
College/School/MBU: College of Natural Sciences
Department: Veterinary & Animal Sciences
Work Location: Amherst
Schedule: Full Time
Work Arrangement: Onsite
Job Summary
The Upi Lab in the Department of Veterinary and Animal Sciences (VASCI) at the University of Massachusetts Amherst is seeking a highly motivated Postdoctoral Research Fellow to investigate immunometabolic regulation of tissue-resident immune cells in mucosal tissues. Research in the laboratory focuses on understanding how nutrient sensing, metabolism, and immune-epithelial interactions shape chronic inflammatory diseases, colorectal cancer, HIV-associated gut dysfunction, and reproductive mucosal health. The successful candidate will develop independent research projects while contributing to collaborative and translational studies utilizing human tissues, mouse models, organoids, single-cell genomics, and advanced imaging approaches.
Essential Functions
Research projects in the laboratory focus on, immunometabolic regulation of tissue-resident T cells, chronic inflammatory diseases of the gastrointestinal and reproductive tracts, early-onset colorectal cancer and HIV-associated mucosal dysfunction.
Nutrient sensing and immune adaptation at barrier tissues.
Design, conduct, and analyze experiments related to mucosal immunology and immunometabolism.
Develop independent research projects aligned with the laboratory's mission.
Perform studies using mouse models, organoids, human tissue samples, flow cytometry, microscopy, and molecular biology techniques.
Participate in collaborative projects across UMass and external institutions.
Prepare manuscripts for publication in high-impact journals.
Present findings at national and international scientific meetings.
Contribute to grant applications and fellowship submissions.
Mentor graduate students, undergraduate researchers, and technicians.
Assist with establishing laboratory protocols and research infrastructure.
Contribute to a collaborative and inclusive laboratory environment.
Other Functions
Work collaboratively and effectively to promote teamwork, equality and inclusiveness.
Work in partnership with colleagues within the CNS community and across the campus to support the Dean’s strategic priorities.
Perform other duties as assigned in support of the mission and goals of the College of Natural Sciences.
Minimum Qualifications
PhD, MD, or equivalent doctoral degree in Immunology, Cell Biology, Cancer Biology, Molecular Biology, Bioengineering, or a related field.
Demonstrated publication record in peer-reviewed journals.
Experience in at least one of the following areas: immunology, metabolism, cancer biology, mucosal biology, stem cell biology, microbiology, or computational biology.
Strong written and oral communication skills.
Ability to work both independently and collaboratively.
Preferred Qualifications
Experience with flow cytometry, single-cell RNA sequencing, spatial biology, metabolomics, organoid culture, or animal models.
Experience analyzing transcriptomic or other high-dimensional datasets.
Interest in pursuing an academic, biotechnology, or translational research career.
Prior experience mentoring trainees.
Additional Details
This is a temporary, grant funded position.
At UMass Amherst and in CNS, we strive to be a community where every individual feels a sense of belonging, where every individual is included, and where every individual is valued. These values and goals are reflected in the College of Natural Sciences’ Inclusive Excellence framework and in the UMass Amherst’s For the Common Good: 2024–2034 Strategic Plan.
Working Conditions
Work is performed in a laboratory or healthcare setting and may involve exposure to chemicals or infectious diseases. Requires standing for extended periods of time and/or use of protective gear.
Work Schedule and Work Arrangement
Monday – Friday 8:30am – 5:00pm and may have to be altered occasionally to accommodate timing of experiments and other factors.
Salary Information
Salary minimum is determined by collective bargaining agreement based on years of experience. Salary may exceed the floor and will be determined by the PI (final salary will be stated in offer letter).
Current salary floors based on 100% time, 40 hours/week:
0-2 years $62,838
3-4 years $66,287
5+ years $71,033
Special Instructions for Applicants
Along with the application, please submit a resume and a cover letter. References will be checked at the finalist stage. Please be prepared to provide contact information for three (3) professional references. Applications will be reviewed on a continuous basis until the position is filled. Early submissions are encouraged.
This position will remain open for the time period required by any applicable collective bargaining agreement and will continue until a suitable candidate pool is identified. Interested applicants are strongly encouraged to apply early.
STEM OPT Nonprofit Job Roles in Massachusetts
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Search Nonprofit Jobs in MassachusettsNonprofit STEM OPT Sponsorship Jobs in Massachusetts: Frequently Asked Questions
Which nonprofit organizations in Massachusetts commonly sponsor F-1 STEM OPT visas?
Massachusetts nonprofits with documented histories of STEM OPT sponsorship include large academic medical centers such as Dana-Farber Cancer Institute, Mass General Brigham, and Beth Israel Deaconess Medical Center, as well as research-focused organizations like the Broad Institute and the Woods Hole Oceanographic Institution. Public health nonprofits and university-affiliated research centers in the Boston and Cambridge area also frequently hire STEM OPT candidates for data and analytics roles.
Which cities in Massachusetts have the most nonprofit F-1 STEM OPT sponsorship jobs?
Boston and Cambridge account for the highest concentration of nonprofit STEM OPT positions in Massachusetts, driven by the density of academic medical centers, research hospitals, and university-affiliated nonprofits. Worcester is a secondary market with healthcare nonprofits connected to UMass Medical School. Springfield and Lowell have smaller but active nonprofit sectors, primarily in social services and public health, with occasional STEM-designated openings in data and program analysis roles.
What types of nonprofit roles in Massachusetts typically qualify for F-1 STEM OPT sponsorship?
Roles must fall under a STEM-designated Classification of Instructional Programs code tied to your degree. In Massachusetts nonprofits, qualifying positions commonly include biostatistician, data analyst, health informatics specialist, research coordinator, epidemiologist, and environmental scientist. Program evaluation and public health data roles at organizations like the Massachusetts Health Policy Commission or research affiliates of Harvard and MIT also frequently meet the STEM OPT occupational and degree-alignment requirements set by USCIS.
How do I find nonprofit F-1 STEM OPT sponsorship jobs in Massachusetts?
Migrate Mate filters job listings specifically for F-1 STEM OPT eligibility and nonprofit employers in Massachusetts, showing verified sponsorship history so you can focus on organizations that have sponsored similar roles before. Beyond the platform, cross-reference employer filings in the OFLC Wage Search to confirm a nonprofit has filed Labor Condition Applications for roles, which signals familiarity with the sponsorship process for international students.
Are there any Massachusetts-specific considerations for F-1 STEM OPT sponsorship at nonprofits?
Massachusetts nonprofits must comply with all federal STEM OPT employer requirements, including E-Verify enrollment and submitting a formal training plan through your DSO before your OPT start date. The state has a high concentration of cap-exempt H-1B visa employers, particularly universities and affiliated research nonprofits, which matters if you are planning ahead for visa transitions after STEM OPT. Massachusetts employers in healthcare and research are generally familiar with international hiring but sponsorship timelines and compliance obligations still vary by organization.