Science & Research STEM OPT Jobs in Massachusetts
Massachusetts hosts some of the country's most active science and research employers sponsoring F-1 STEM OPT workers, from biotechnology giants like Moderna and Biogen in the Boston-Cambridge corridor to academic research institutions and defense contractors across the state. Life sciences, computational biology, and materials science roles in Greater Boston and Worcester drive the highest concentration of STEM OPT sponsorship activity.
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About us
Deep Genomics is at the forefront of integrating artificial intelligence and complex biology to transform drug discovery. Our proprietary machine learning platform decodes the complexity of RNA biology to identify novel drug targets, mechanisms and therapeutics inaccessible through traditional methods. With expertise spanning machine learning, bioinformatics, data science, genetics, chemistry and drug development, our multidisciplinary team in Toronto and Cambridge, MA is revolutionizing how medicines are created.
About the role
The Senior Research Associate will join our in vivo Pharmacology team within the Platform Biology group and will be a key player in driving our cutting-edge AI RNA therapeutics discovery platform. In this role, you will be responsible for helping support in vivo therapeutic efficacy testing efforts of novel RNA therapeutics in various animal models. The ideal candidate will have strong hands-on experience with in vivo animal handling and rodent models, expertise in tissue collection and sample processing, and some background in molecular biology techniques. Experience or familiarity with RNA-based therapeutic modalities is highly desirable.
The successful candidate will be a proactive, detail-oriented, and collaborative team member who demonstrates scientific curiosity and initiative. The candidate should be comfortable working both mostly independently and within cross-functional teams in a dynamic, fast-paced biotech environment.
This position is onsite at our Cambridge, MA site.
Key Responsibilities
- Coordinate study logistics, including dosing schedules, sample collection plans, reagent preparation, and communication with research partners.
- Manage in vivo samples and prepare samples for downstream analysis.
- Perform standard molecular biology techniques in a consistent and reproducible manner (e.g. PCR, qPCR, ddPCR, ELISA, Western blot, Jess/Leo capillary-based Western blot, etc.).
- Support the development of novel molecular and functional assays on animal samples for our internal therapeutic pipeline.
- Analyze, visualize, and summarize study data while maintaining accurate and timely documentation of experiments, protocols/SOPs, sample inventories, and results in an electronic lab notebook (ELN).
- Collaborate with cross-functional teams to support project goals and meet company timelines.
Basic Qualifications
- Degree in Pharmacology, Biology, Molecular Biology, Genetics, Biochemistry or a related field with a BS and 2-4+ years of relevant experience, a MS and 1-2+ years of relevant pharmaceutical or biotechnology experience.
- Basic understanding of molecular biology and tissue sample processing for RNA and protein readouts.
- Hands on experience with rodents, basic injections (ex. tail vein, SubQ, IP, etc.), necropsy, and some in vivo study coordination is mandatory.
- Demonstrate ability to execute various ex vivo molecular assays.
- Excellent communication, organizational skills and a willingness to learn.
- Ability to work collaboratively in a fast-paced technical environment.
Preferred Qualifications
- Past experience with RNA oligonucleotide therapeutics in animal models is preferred.
- Basic knowledge of histology and immunohistochemical assays and quantification is a bonus.
- Demonstrated experience working in cross-functional teams.
- Experience working in an advanced data and computing environment.
What We Offer
- A collaborative and innovative environment at the frontier of computational biology, machine learning, and drug discovery.
- Highly competitive compensation, including meaningful stock ownership.
- Comprehensive benefits - including health, vision, and dental coverage for employees and families, employee and family assistance program.
- Flexible work environment - including flexible hours, extended long weekends, holiday shutdown, unlimited personal days.
- Maternity and parental leave top-up coverage, as well as new parent paid time off.
- Focus on learning and growth for all employees - learning and development budget & lunch and learns.
- Facilities located in the heart of Toronto - the epicenter of machine learning and AI research and development, and in Kendall Square, Cambridge, Mass. - a global center of biotechnology and life sciences.
Deep Genomics encourages applications from all backgrounds who seek the opportunity to build the world's leading AI-driven genetic medicine company.
If you have a disability or special need, accommodation is available on request for candidates taking part in all aspects of the selection process.
This posting reflects a current vacancy.
We offer competitive compensation aligned with local market benchmarks. The salary range for this role is $90,000 - 110,000, and reflects Cambridge, USA-based roles.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
STEM OPT Science & Research Job Roles in Massachusetts
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Search Science & Research Jobs in MassachusettsScience & Research STEM OPT Sponsorship Jobs in Massachusetts: Frequently Asked Questions
Which science and research companies sponsor F-1 STEM OPT visas in Massachusetts?
Massachusetts has a dense cluster of science and research employers with documented STEM OPT sponsorship history, including Biogen, Moderna, Takeda, MilliporeSigma, and Charles River Laboratories in the life sciences space, alongside defense and materials research firms like Raytheon Technologies and Draper Laboratory. Academic medical centers such as Massachusetts General Hospital and Brigham and Women's Hospital also hire STEM OPT researchers in laboratory and clinical science roles.
Which cities in Massachusetts have the most science and research F-1 STEM OPT sponsorship jobs?
Cambridge and Boston together form the country's most concentrated life sciences and biotech hub, making them the top cities for STEM OPT sponsorship in science and research. Waltham and Lexington host major pharmaceutical and defense research campuses. Worcester has a growing biomedical research presence anchored by UMass Medical School and the biotechnology corridor along Route 9. Lowell and Andover attract materials science and semiconductor research employers.
What types of science and research roles typically qualify for F-1 STEM OPT sponsorship in Massachusetts?
Roles with STEM-designated Classification of Instructional Programs codes that consistently qualify include research scientist, computational biologist, biostatistician, biochemist, materials scientist, data scientist in research settings, and laboratory analyst positions. The role must appear on your school's STEM OPT designation list and require direct application of your degree field. Positions classified under life sciences, physical sciences, mathematics, or computer and information sciences STEM degree classifications are most commonly approved by employers in Massachusetts.
How do I find science and research F-1 STEM OPT sponsorship jobs in Massachusetts?
Migrate Mate filters science and research job listings in Massachusetts by verified STEM OPT sponsorship history, so you can focus on employers who have a documented record of supporting F-1 workers in research roles rather than cold-applying to companies with no track record. You can filter by location, role type, and visa category directly on the platform. Combining Migrate Mate's employer data with OFLC Wage Search helps you confirm prevailing wage levels for specific research occupations before you apply.
Are there any Massachusetts-specific considerations for F-1 STEM OPT sponsorship in science and research?
Massachusetts has no state-level work authorization requirements beyond federal STEM OPT rules, but the competitive concentration of research talent in Greater Boston means employers often move quickly through interview cycles. Many life sciences employers in Massachusetts are enrolled in E-Verify as a condition of federal research contracts, which is a requirement for STEM OPT employers under federal regulations. Researchers working on federally funded grants should confirm that their specific project and employment classification align with STEM OPT eligibility before accepting an offer.