Operations Director Visa Sponsorship Jobs in Massachusetts
Massachusetts operations director roles are concentrated in Boston's life sciences corridor, financial services firms in the Seaport District, and major healthcare systems like Mass General Brigham and Boston Children's Hospital. Large employers in biotechnology, higher education, and defense contracting have established HR infrastructure to support visa sponsorship for senior operations talent.
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Job Title: Commercial Strategy and Operations Director - Rhinology/Gastro/Allergy
Location: Cambridge, MA
About the Job
Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs.
We are seeking a highly strategic and execution-focused Chief of Staff to partner with the General Manager, US Dupixent RGA (Rhinology/Gastro/Allergy). The Director of Commercial Strategy & Operations role sits at the center of the franchise, driving strategic execution and operational excellence, accelerating business performance, and embedding AI-enabled ways of working across teams. You will act as a force multiplier for the GM ensuring priorities are aligned, decisions are data-driven, and initiatives are executed with speed and rigor. This is a unique opportunity to operate at the highest levels of a U.S. pharma team, shaping both business performance and the future of how work gets done through AI.
This individual will play a significant role in translating strategy into action and implementing high-impact projects in line with the franchise overall business objectives. This role will involve cross functional collaboration with Marketing, Sales, Insights & Analytics, TLL, PSS, Finance, Market Access, and Medical Affairs as well as the Global team. They will be responsible for overseeing the strategic business planning process, synthesizing complex data into actionable insights, and proactively identifying opportunities and strategies for growth. This role will champion AI adoption, identifying high-impact use cases and work with teams to embed internal AI tools into day-to-day workflows.
About Sanofi
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Main responsibilities:
- Design and execute operational planning including leading weekly leadership team meetings, offsites and governance meetings with clear outcomes and accountability and driving behavior of high-performing team
- Establish robust governance frameworks that drive decision-making velocity and cross-functional alignment
- Partner with leadership to translate strategy into executable tactics to achieve franchise business objectives
- Lead high-priority acceleration projects with measurable impact on business performance
- Champion AI transformation through directed projects – serve as ambassador for AI and partner with teams to build AI fluency, enabling smarter, faster, and more data-driven decisions
- Identify and remove organizational bottlenecks to accelerate decision-making and execution
- Own the strategic business planning and budget process for Budget/C1/C2 Strategic plan with scenario planning and risk assessment
- Provide strategic counsel to US Head of RGA through business intelligence, trend analysis, and proactive issue identification
- Synthesize complex data from US and Global colleagues to create compelling narratives for business reviews
- Drive prioritization and execution of commercial activities; ensure knowledge sharing and alignment across brands
- Lead analytical deep-dives in partnership with Marketing and Global to uncover growth opportunities
- Serve as strategic proxy for GM in meetings, events and critical business decisions
- Craft executive-level communications and presentations for internal and external stakeholders including Investor Relations
- Execute mission-critical cross-brand initiatives leveraging functional relationships to deliver measurable outcomes
- Manage Alliance governance with strategic oversight and clear communication protocols
- Optimize leadership effectiveness: foster collaboration, facilitate difficult conversations, create structured decision-making processes
- Drive culture transformation initiatives that enhance employee engagement and business performance
Desired Traits:
- Strategic mindset with execution excellence - translates vision into results
- Intellectual & learning agility - thrives in ambiguous, fast-paced environments with competing priorities
- Uncompromising integrity - trusted advisor with absolute discretion
- Collaborative leadership - influences without authority, builds coalitions
- Emotional intelligence with courageous communication - voices difficult truths constructively
- Growth mindset - continuously learns and adapts
- Executive presence - remains composed under pressure, inspires confidence
Main requirements:
- Bachelor's degree required, MBA strongly preferred
- 7-10 years experience in top-tier consulting, commercial operations, sales/marketing, digital health roles
- Proven track record of driving strategic initiatives with measurable business impact
- Strong understanding of U.S. pharmaceutical landscape (commercial, regulatory, and market dynamics)
- Hands-on experience with AI tools and applications (e.g., LLMs, automation, analytics) and a passion for scaling adoption
- Demonstrated experience driving operational improvements and performance management
- Exceptional problem-solving, communication, and stakeholder management skills
- Ability to operate in a fast-paced, ambiguous environment with a high degree of ownership
- Executive-level communication and presentation skills with C-suite experience
- Expert project management with ability to manage multiple complex initiatives simultaneously
- Matrix leadership excellence - drives results through influence and relationship-building across all functions
Why Choose Us?
- Bring the miracles of science to life alongside a supportive, future-focused team.
- Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Job Title: Commercial Strategy and Operations Director - Rhinology/Gastro/Allergy
Location: Cambridge, MA
About the Job
Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs.
We are seeking a highly strategic and execution-focused Chief of Staff to partner with the General Manager, US Dupixent RGA (Rhinology/Gastro/Allergy). The Director of Commercial Strategy & Operations role sits at the center of the franchise, driving strategic execution and operational excellence, accelerating business performance, and embedding AI-enabled ways of working across teams. You will act as a force multiplier for the GM ensuring priorities are aligned, decisions are data-driven, and initiatives are executed with speed and rigor. This is a unique opportunity to operate at the highest levels of a U.S. pharma team, shaping both business performance and the future of how work gets done through AI.
This individual will play a significant role in translating strategy into action and implementing high-impact projects in line with the franchise overall business objectives. This role will involve cross functional collaboration with Marketing, Sales, Insights & Analytics, TLL, PSS, Finance, Market Access, and Medical Affairs as well as the Global team. They will be responsible for overseeing the strategic business planning process, synthesizing complex data into actionable insights, and proactively identifying opportunities and strategies for growth. This role will champion AI adoption, identifying high-impact use cases and work with teams to embed internal AI tools into day-to-day workflows.
About Sanofi
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Main responsibilities:
- Design and execute operational planning including leading weekly leadership team meetings, offsites and governance meetings with clear outcomes and accountability and driving behavior of high-performing team
- Establish robust governance frameworks that drive decision-making velocity and cross-functional alignment
- Partner with leadership to translate strategy into executable tactics to achieve franchise business objectives
- Lead high-priority acceleration projects with measurable impact on business performance
- Champion AI transformation through directed projects – serve as ambassador for AI and partner with teams to build AI fluency, enabling smarter, faster, and more data-driven decisions
- Identify and remove organizational bottlenecks to accelerate decision-making and execution
- Own the strategic business planning and budget process for Budget/C1/C2 Strategic plan with scenario planning and risk assessment
- Provide strategic counsel to US Head of RGA through business intelligence, trend analysis, and proactive issue identification
- Synthesize complex data from US and Global colleagues to create compelling narratives for business reviews
- Drive prioritization and execution of commercial activities; ensure knowledge sharing and alignment across brands
- Lead analytical deep-dives in partnership with Marketing and Global to uncover growth opportunities
- Serve as strategic proxy for GM in meetings, events and critical business decisions
- Craft executive-level communications and presentations for internal and external stakeholders including Investor Relations
- Execute mission-critical cross-brand initiatives leveraging functional relationships to deliver measurable outcomes
- Manage Alliance governance with strategic oversight and clear communication protocols
- Optimize leadership effectiveness: foster collaboration, facilitate difficult conversations, create structured decision-making processes
- Drive culture transformation initiatives that enhance employee engagement and business performance
Desired Traits:
- Strategic mindset with execution excellence - translates vision into results
- Intellectual & learning agility - thrives in ambiguous, fast-paced environments with competing priorities
- Uncompromising integrity - trusted advisor with absolute discretion
- Collaborative leadership - influences without authority, builds coalitions
- Emotional intelligence with courageous communication - voices difficult truths constructively
- Growth mindset - continuously learns and adapts
- Executive presence - remains composed under pressure, inspires confidence
Main requirements:
- Bachelor's degree required, MBA strongly preferred
- 7-10 years experience in top-tier consulting, commercial operations, sales/marketing, digital health roles
- Proven track record of driving strategic initiatives with measurable business impact
- Strong understanding of U.S. pharmaceutical landscape (commercial, regulatory, and market dynamics)
- Hands-on experience with AI tools and applications (e.g., LLMs, automation, analytics) and a passion for scaling adoption
- Demonstrated experience driving operational improvements and performance management
- Exceptional problem-solving, communication, and stakeholder management skills
- Ability to operate in a fast-paced, ambiguous environment with a high degree of ownership
- Executive-level communication and presentation skills with C-suite experience
- Expert project management with ability to manage multiple complex initiatives simultaneously
- Matrix leadership excellence - drives results through influence and relationship-building across all functions
Why Choose Us?
- Bring the miracles of science to life alongside a supportive, future-focused team.
- Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
Operations Director Job Roles in Massachusetts
See all 178+ Operations Director Jobs in Massachusetts
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Search Operations Director Jobs in MassachusettsOperations Director Jobs in Massachusetts: Frequently Asked Questions
Which companies in Massachusetts sponsor visas for operations directors?
Large employers with consistent operations director sponsorship records in Massachusetts include Biogen, Takeda Pharmaceuticals, Raytheon Technologies, Fidelity Investments, and Massachusetts General Hospital. Major universities like Harvard and MIT also sponsor senior operations roles. Companies of this size have dedicated immigration counsel and established sponsorship processes, making them more reliable sponsors than smaller firms.
Which visa types are most common for operations director roles in Massachusetts?
The H-1B is the most common visa for operations directors in Massachusetts, provided the role requires a specialized bachelor's degree or higher in a field directly related to the position. The L-1A is frequently used by multinational companies transferring operations leaders from overseas offices. Senior candidates with exceptional records may also qualify for the O-1A or EB-1C immigrant visa categories.
Which cities in Massachusetts have the most operations director sponsorship jobs?
Boston accounts for the majority of operations director sponsorship activity in the state, driven by its concentration of hospitals, financial institutions, and technology companies. Cambridge is a secondary hub, anchored by biotech and pharmaceutical firms clustered around Kendall Square. Worcester and Lowell have a smaller but active manufacturing and healthcare operations hiring presence worth monitoring.
How to find operations director visa sponsorship jobs in Massachusetts?
Migrate Mate filters job listings specifically by visa sponsorship availability, making it straightforward to identify Massachusetts employers actively hiring operations directors who need sponsorship. Rather than sorting through general postings, Migrate Mate surfaces roles where sponsorship is confirmed, which is particularly useful for senior operations positions where sponsorship willingness varies significantly by company size and sector.
Are there any state-specific considerations for operations director visa sponsorship in Massachusetts?
Massachusetts has a high concentration of H-1B-dependent employers in life sciences and technology, meaning some firms must meet additional attestation requirements when hiring foreign workers. The state's strong university pipeline, including MIT, Harvard, and Northeastern, means many employers are familiar with OPT-to-H-1B transitions for candidates already in the U.S. Operations director roles in regulated industries like healthcare or defense may also require specific compliance experience that affects how employers frame sponsorship decisions.
What is the prevailing wage for sponsored operations director jobs in Massachusetts?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.
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