Associate Director Clinical Operations Jobs in USA with Visa Sponsorship
Associate Director Clinical Operations roles sit at the intersection of science and management, making them strong candidates for H-1B visa sponsorship. Most require a life sciences degree and significant clinical trial experience, and employers at biotech and CRO firms regularly sponsor this level. For detailed occupation requirements, see the O*NET profile.
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Get Access To All JobsINTRODUCTION
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
THE OPPORTUNITY:
As an Associate Director, you will be responsible for the following:
- Lead and/or support development and implementation of GCP systems and inspection readiness.
- Lead and/or support the development and continuous improvement of Clinical Policies/ SOPs/ WIs/ Templates/etc. using knowledge and experience with clinical study management, International Conference on Harmonization (ICH) Guidelines, Good Clinical Practices (GCP) and regulatory requirements.
- SME for Clinical Operations GCP guidance, best industry practices, SOPs, and audit responses.
- Contribute to the development and management of business and compliance metrics to assess and continuously improve RevMed oversight and inspection readiness throughout the clinical trial lifecycle.
- Support Clinical Operations Inspection Readiness activities with clinical study teams; key participation in Mock/Regulatory Authority inspections.
- Contribute to the development and execution of Clinical Operations training programs to deliver RevMed standards, GCP, and regulatory requirements.
- Partner cross-functionally and with QA on quality initiatives, continuous improvement of GCP systems, and internal audits.
- Line management responsibilities including hiring, performance management, career development, and mentorship.
- Participate in other Clinical Operations Activities per the business need.
REQUIRED SKILLS, EXPERIENCE AND EDUCATION:
- Bachelor’s degree in biological sciences or health-related field required.
- 10+ years direct Clinical Compliance, and/or Clinical Quality Assurance experience in the pharmaceutical or biotech industry. Relevant Clinical Operations experiences may also meet the requirement.
- Strong working knowledge of FDA Regulations, ICH Guidelines, and GCP.
- Demonstrated experience successfully developing and authoring Clinical and cross-functional SOPs ensuring compliance with GCP and regulatory requirements.
- Experience with development and monitoring of oversight activities.
- Knowledge and/or familiarity with Ex-US region(s) e.g. EMA, MHRA, PDMA.
- Ability to perform complex assessments & investigations, draw relevant conclusions, and implement appropriate solutions.
- Strong analytical, negotiation, and persuasion skills.
- Ability to deal with time demands, incomplete information, or unexpected events.
- Outstanding organizational skills with the ability to multi-task and prioritize.
- Excellent interpersonal, verbal, and written communication skills.
- Decision-making skills.
- Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.
- Demonstrate proficiency in Microsoft Office Suite (Outlook, MS Word, Excel, PowerPoint); MS Project and/or Smartsheet a plus.
- Travel may be required (~25%).
PREFERRED SKILLS:
- Line Management experience.
- Oncology experience, early and/or late stage, strongly preferred.
- RN or Master’s degree in biological sciences or health-related field preferred.
- Strong working knowledge of ex-US regulations and requirements.
COMPENSATION
- Base Pay Salary Range: $186,000 - $233,000 USD
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.
INTRODUCTION
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
THE OPPORTUNITY:
As an Associate Director, you will be responsible for the following:
- Lead and/or support development and implementation of GCP systems and inspection readiness.
- Lead and/or support the development and continuous improvement of Clinical Policies/ SOPs/ WIs/ Templates/etc. using knowledge and experience with clinical study management, International Conference on Harmonization (ICH) Guidelines, Good Clinical Practices (GCP) and regulatory requirements.
- SME for Clinical Operations GCP guidance, best industry practices, SOPs, and audit responses.
- Contribute to the development and management of business and compliance metrics to assess and continuously improve RevMed oversight and inspection readiness throughout the clinical trial lifecycle.
- Support Clinical Operations Inspection Readiness activities with clinical study teams; key participation in Mock/Regulatory Authority inspections.
- Contribute to the development and execution of Clinical Operations training programs to deliver RevMed standards, GCP, and regulatory requirements.
- Partner cross-functionally and with QA on quality initiatives, continuous improvement of GCP systems, and internal audits.
- Line management responsibilities including hiring, performance management, career development, and mentorship.
- Participate in other Clinical Operations Activities per the business need.
REQUIRED SKILLS, EXPERIENCE AND EDUCATION:
- Bachelor’s degree in biological sciences or health-related field required.
- 10+ years direct Clinical Compliance, and/or Clinical Quality Assurance experience in the pharmaceutical or biotech industry. Relevant Clinical Operations experiences may also meet the requirement.
- Strong working knowledge of FDA Regulations, ICH Guidelines, and GCP.
- Demonstrated experience successfully developing and authoring Clinical and cross-functional SOPs ensuring compliance with GCP and regulatory requirements.
- Experience with development and monitoring of oversight activities.
- Knowledge and/or familiarity with Ex-US region(s) e.g. EMA, MHRA, PDMA.
- Ability to perform complex assessments & investigations, draw relevant conclusions, and implement appropriate solutions.
- Strong analytical, negotiation, and persuasion skills.
- Ability to deal with time demands, incomplete information, or unexpected events.
- Outstanding organizational skills with the ability to multi-task and prioritize.
- Excellent interpersonal, verbal, and written communication skills.
- Decision-making skills.
- Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.
- Demonstrate proficiency in Microsoft Office Suite (Outlook, MS Word, Excel, PowerPoint); MS Project and/or Smartsheet a plus.
- Travel may be required (~25%).
PREFERRED SKILLS:
- Line Management experience.
- Oncology experience, early and/or late stage, strongly preferred.
- RN or Master’s degree in biological sciences or health-related field preferred.
- Strong working knowledge of ex-US regulations and requirements.
COMPENSATION
- Base Pay Salary Range: $186,000 - $233,000 USD
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.
See all Associate Director Clinical Operations Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Associate Director Clinical Operations roles.
Get Access To All JobsTips for Finding Associate Director Clinical Operations Jobs
Target biotech and CRO employers specifically
Large contract research organizations and mid-size biotech firms sponsor Associate Director Clinical Operations roles far more consistently than academic medical centers or startups. Their established legal teams make sponsorship a standard part of senior clinical hiring.
Align your degree to the specialty occupation requirement
H-1B approval for this role requires a bachelor's degree or higher in a relevant field. Life sciences, nursing, pharmacy, or public health are strong fits. A general business degree alone is unlikely to satisfy the specialty occupation standard for clinical operations.
Emphasize your therapeutic area depth
Oncology, rare disease, and CNS experience are in high demand and narrow the candidate pool considerably. Sponsoring employers move faster when a candidate fills a hard-to-recruit niche, so positioning your expertise clearly strengthens your sponsorship case.
Understand the H-1B timeline before accepting an offer
If you need a new H-1B, the lottery runs in March for an October 1 start. Some employers can file cap-exempt through affiliated research institutions. Clarify your status and the employer's willingness to petition before signing anything.
Transferring an existing H-1B speeds up the process significantly
If you already hold H-1B status, a new employer can file a transfer petition and you can begin working as soon as the receipt notice is issued. This removes the lottery risk entirely and is the smoothest path for experienced candidates.
Director-level framing supports the LCA wage tier
The Labor Condition Application requires the employer to pay the prevailing wage for the role and location. Associate Director roles typically fall at wage level III or IV, which strengthens the specialty occupation argument and reduces the risk of an LCA challenge.
Frequently Asked Questions
Do employers actually sponsor Associate Director Clinical Operations roles?
Yes, and at a meaningful rate. This is a senior individual contributor or people manager role that requires specialized clinical trial expertise, which makes it difficult to fill domestically. Biotech companies, large CROs, and pharmaceutical firms regularly file H-1B visa petitions for this title. Sponsorship is less common at early-stage startups without established HR infrastructure.
What degree do I need for H-1B approval in this role?
A bachelor's degree or higher in a field directly related to clinical operations is required for the specialty occupation determination. Life sciences, nursing, pharmacy, clinical research, or public health are the strongest fits. Degrees in unrelated fields create risk even if you have years of relevant experience, because USCIS evaluates whether the degree requirement is standard across the industry for this specific role.
Where can I find Associate Director Clinical Operations jobs that offer visa sponsorship?
Migrate Mate filters job listings specifically by sponsorship willingness, so you can browse Associate Director Clinical Operations openings without sorting through roles that won't consider visa candidates. This saves significant time compared to applying broadly and asking about sponsorship mid-process, when it's harder to negotiate.
Can I qualify for an O-1A visa in clinical operations instead of H-1B?
It's possible but uncommon at the Associate Director level unless you have an unusually distinguished record. O-1A requires demonstrated extraordinary ability through criteria such as published research, judging others' work, or receiving major awards in the field. Most clinical operations professionals at this level don't meet that bar without also having a research or academic profile alongside their operational experience.
How does the H-1B lottery affect my chances of getting sponsored for this role?
If you need a new H-1B cap-subject petition, selection depends on the annual lottery, which ran at roughly a 25% selection rate in recent years. Employers who are serious about hiring you will file in March and plan around an October 1 start. If your employer has an affiliation with a nonprofit research institution or university, they may qualify for cap-exempt filing, which bypasses the lottery entirely.
What is the prevailing wage requirement for sponsored Associate Director Clinical Operations jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.