Global Project Manager Jobs in USA with Visa Sponsorship
Global Project Managers are strong candidates for H-1B visa and L-1 visa sponsorship, particularly at multinational firms that routinely sponsor cross-border roles. Employers value PMP credentials and international experience, which strengthen both visa petitions and salary benchmarks under Labor Condition Application requirements. For detailed occupation requirements, see the O*NET profile.
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Get Access To All JobsWork Schedule
Standard (Mon-Fri)
Environmental Conditions
Office
Job Description
Join Us as a Senior Project Manager - Make an Impact at the Forefront of Innovation. Lead or support study operational strategy and planning and oversee execution of select clinical studies (global/regional and/or local country) for assigned clinical program(s), supporting clinical strategy defined in Clinical Development Plan.
In close collaboration with the Clinical Operations Program Lead (COPL) and the Clinical Operations Manager (COM) (if applicable):
- Support or oversee the execution of select study/ies in assigned clinical program(s) in compliance with quality standards (including ICH GCP, local regulations and Client SOPs), on schedule and on budget.
- Oversee Strategic Partners and/or other CROs and other vendors to meet the client obligations described in ICH-GCP and client business objectives.
Studies may include but are not limited to PTA (Post Trial Access), RATIO (R&D Asset Transition and Integration Office), those in wind down, etc. More than one study and/or more than one program may be assigned.
ACCOUNTABILITIES:
- Accountable for planning and operational strategy and execution for assigned clinical trials
- Provides subject matter expertise and operational input into protocol synopsis, final protocol and other study related documents
- Challenges study team to ensure operational feasibility, inclusive of patient and site burden
- Supports budget development and ensures impacts are adequately addressed
- Participates in country and site feasibility/selection process, with a focus on providing country insights, alignment and therapeutic expertise to ensure alignment between study execution plan and program strategy
- Develops and manages study timelines
- Challenges study team to ensure timelines meet the needs of the clinical development plan
- Ensures new team members and vendors are appropriately onboarded
- Identifies and oversees trial risk and mitigation
- Leader of the cross functional study team
- During Early Engagement with Strategic Partner(s) and/or other CROs, lead the development of the Operational Strategy in preparation for Operational Strategy Review; focus on ensuring accurate assumptions are applied and robust risk management plans are in place
- Provide oversight/support/guidance to Strategic partners/CRO to ensure study issues are addressed and resolved rapidly
- Supports/reviews study budget planning and management and accountable for external spend related to study execution. Works closely with COM (if applicable) and COPL, Global Program Management, and Finance to ensure on a regular basis that budgets, enrollment, and gaiting are accurate; Communicates study status, cost and issues to COM and COPL; serve as escalation point for all vendors managed by Strategic Partner and/or other CROs
- Oversee Strategic Partners/CRO/vendor selection, budget and contract negotiation, and proper supervision of performance for all activities assigned to a Strategic Partner/CRO/vendor for assigned studies, including escalation of issues to governance committees when warranted;
- Specific areas of sponsor oversight include, but are not limited to:
- Review and approval of key monitoring documents/plans, periodic review of outputs, decisions and actions related to monitoring
- Conduct Oversight Monitoring Visits, as applicable
- Review and endorsement of relevant study plans, as applicable
- Study team meeting management and attendance when necessary; regular review of meeting agendas and minutes
- Review of outcomes/actions related to protocol deviations review; primary purpose of review is to support the identification of trends across sites and/or the study
- Documented review and monitoring of issues, risks and decisions at the study level and implementation of appropriate mitigation strategies
- Review and ownership of trial operational data (e.g. CTMS)
- Review and provide oversight of internal trial reports
- In partnership with data management, review and pressure test all database timelines and plans; ensure strong linkage between the strategy (i.e., filing/registration, data generation, etc.) with the tactical plan for database lock and CSR.
- Support data review for database lock and CSR writing and review (including appendices)
- Collect/review/File study documents in support of the trial master file (TMF)
- Collect/review/File study documents in support of the regulatory filing
- Responsible for overseeing study financial reconciliation
- Ensure studies are “inspection ready” at all times; may be involved in regulatory inspections by preparing for and/or attending the inspections.
- Site relationship management
- Review and provide oversight of trial audits
- Proper and timely follow up to audit findings and CAPAs
- Preparation for Agency inspections, including document readiness, tracking, storyboard development and other pertinent documents and preparations
EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS:
Education: Bachelor’s Degree or international equivalent required; Life Sciences preferred.
Skills:
- Knowledge in global regulatory and compliance requirements for clinical research, including but not limited to US CFR, EU CTD, and ICH GCP. Awareness of local country requirements is also required.
- Demonstrated successful experience in project/program management and matrix leadership
- E.g. timeline/budget management
- E.g. Risk identification and management
- Works independently and is highly organized
- Good communication skills
- Excellent teamwork, organizational, interpersonal, and problem-solving skills, including experience with Leading cross-functional teams, vendor selection and oversight
- Experience managing recruitment challenges and boosting enrollment
- Fluent business English (oral and written)
Experience: 8+ years’ experience in pharmaceutical industry and/or clinical research organization, including 3+ years clinical study management/oversight, including significant study management support experience (e.g. clinical trial assistant/associate or lead CRA). 2+ years of experience in global lead project management field. Oncology experience is required (as lead PM or Lead CTM). Extensive ICF experience required (on a country and site level). Experience could include either early phase clinical studies or Phase 2 and 3 studies and global/international studies or programs. Experience in more than one therapeutic area is advantageous.
Advanced degree(s) (e.g., Master or Doctorate) and relevant training or experience (e.g., fellowship, internships, etc.) may be considered to supplement experience requirements.
Why Join Us?
When you join Thermo Fisher Scientific, you become part of a global team that values passion, innovation, and a commitment to scientific excellence. You’ll work in an environment where collaboration and development are part of the everyday experience—and where your contributions truly make a difference.
Apply today to help us deliver tomorrow’s breakthroughs.
Work Schedule
Standard (Mon-Fri)
Environmental Conditions
Office
Job Description
Join Us as a Senior Project Manager - Make an Impact at the Forefront of Innovation. Lead or support study operational strategy and planning and oversee execution of select clinical studies (global/regional and/or local country) for assigned clinical program(s), supporting clinical strategy defined in Clinical Development Plan.
In close collaboration with the Clinical Operations Program Lead (COPL) and the Clinical Operations Manager (COM) (if applicable):
- Support or oversee the execution of select study/ies in assigned clinical program(s) in compliance with quality standards (including ICH GCP, local regulations and Client SOPs), on schedule and on budget.
- Oversee Strategic Partners and/or other CROs and other vendors to meet the client obligations described in ICH-GCP and client business objectives.
Studies may include but are not limited to PTA (Post Trial Access), RATIO (R&D Asset Transition and Integration Office), those in wind down, etc. More than one study and/or more than one program may be assigned.
ACCOUNTABILITIES:
- Accountable for planning and operational strategy and execution for assigned clinical trials
- Provides subject matter expertise and operational input into protocol synopsis, final protocol and other study related documents
- Challenges study team to ensure operational feasibility, inclusive of patient and site burden
- Supports budget development and ensures impacts are adequately addressed
- Participates in country and site feasibility/selection process, with a focus on providing country insights, alignment and therapeutic expertise to ensure alignment between study execution plan and program strategy
- Develops and manages study timelines
- Challenges study team to ensure timelines meet the needs of the clinical development plan
- Ensures new team members and vendors are appropriately onboarded
- Identifies and oversees trial risk and mitigation
- Leader of the cross functional study team
- During Early Engagement with Strategic Partner(s) and/or other CROs, lead the development of the Operational Strategy in preparation for Operational Strategy Review; focus on ensuring accurate assumptions are applied and robust risk management plans are in place
- Provide oversight/support/guidance to Strategic partners/CRO to ensure study issues are addressed and resolved rapidly
- Supports/reviews study budget planning and management and accountable for external spend related to study execution. Works closely with COM (if applicable) and COPL, Global Program Management, and Finance to ensure on a regular basis that budgets, enrollment, and gaiting are accurate; Communicates study status, cost and issues to COM and COPL; serve as escalation point for all vendors managed by Strategic Partner and/or other CROs
- Oversee Strategic Partners/CRO/vendor selection, budget and contract negotiation, and proper supervision of performance for all activities assigned to a Strategic Partner/CRO/vendor for assigned studies, including escalation of issues to governance committees when warranted;
- Specific areas of sponsor oversight include, but are not limited to:
- Review and approval of key monitoring documents/plans, periodic review of outputs, decisions and actions related to monitoring
- Conduct Oversight Monitoring Visits, as applicable
- Review and endorsement of relevant study plans, as applicable
- Study team meeting management and attendance when necessary; regular review of meeting agendas and minutes
- Review of outcomes/actions related to protocol deviations review; primary purpose of review is to support the identification of trends across sites and/or the study
- Documented review and monitoring of issues, risks and decisions at the study level and implementation of appropriate mitigation strategies
- Review and ownership of trial operational data (e.g. CTMS)
- Review and provide oversight of internal trial reports
- In partnership with data management, review and pressure test all database timelines and plans; ensure strong linkage between the strategy (i.e., filing/registration, data generation, etc.) with the tactical plan for database lock and CSR.
- Support data review for database lock and CSR writing and review (including appendices)
- Collect/review/File study documents in support of the trial master file (TMF)
- Collect/review/File study documents in support of the regulatory filing
- Responsible for overseeing study financial reconciliation
- Ensure studies are “inspection ready” at all times; may be involved in regulatory inspections by preparing for and/or attending the inspections.
- Site relationship management
- Review and provide oversight of trial audits
- Proper and timely follow up to audit findings and CAPAs
- Preparation for Agency inspections, including document readiness, tracking, storyboard development and other pertinent documents and preparations
EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS:
Education: Bachelor’s Degree or international equivalent required; Life Sciences preferred.
Skills:
- Knowledge in global regulatory and compliance requirements for clinical research, including but not limited to US CFR, EU CTD, and ICH GCP. Awareness of local country requirements is also required.
- Demonstrated successful experience in project/program management and matrix leadership
- E.g. timeline/budget management
- E.g. Risk identification and management
- Works independently and is highly organized
- Good communication skills
- Excellent teamwork, organizational, interpersonal, and problem-solving skills, including experience with Leading cross-functional teams, vendor selection and oversight
- Experience managing recruitment challenges and boosting enrollment
- Fluent business English (oral and written)
Experience: 8+ years’ experience in pharmaceutical industry and/or clinical research organization, including 3+ years clinical study management/oversight, including significant study management support experience (e.g. clinical trial assistant/associate or lead CRA). 2+ years of experience in global lead project management field. Oncology experience is required (as lead PM or Lead CTM). Extensive ICF experience required (on a country and site level). Experience could include either early phase clinical studies or Phase 2 and 3 studies and global/international studies or programs. Experience in more than one therapeutic area is advantageous.
Advanced degree(s) (e.g., Master or Doctorate) and relevant training or experience (e.g., fellowship, internships, etc.) may be considered to supplement experience requirements.
Why Join Us?
When you join Thermo Fisher Scientific, you become part of a global team that values passion, innovation, and a commitment to scientific excellence. You’ll work in an environment where collaboration and development are part of the everyday experience—and where your contributions truly make a difference.
Apply today to help us deliver tomorrow’s breakthroughs.
See all 429+ Global Project Manager jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Global Project Manager roles.
Get Access To All JobsTips for Finding Visa Sponsorship as a Global Project Manager
Target multinational employers first
Companies with existing global operations are far more likely to sponsor Global Project Manager roles. They have established immigration counsel, prior LCA filings on record, and internal processes that make sponsorship routine rather than a one-off administrative burden.
Leverage intracompany transfer eligibility
If you've worked for a multinational employer abroad for at least one year, you may qualify for an L-1B visa as a specialized knowledge worker. This bypasses the H-1B lottery entirely and is worth exploring before pursuing other sponsorship pathways.
Document cross-functional and international scope
H-1B approval for this role depends on demonstrating specialty occupation status. Quantify your portfolio size, number of countries managed, and cross-functional teams led. Vague job descriptions invite USCIS scrutiny and Requests for Evidence.
Highlight PMP or equivalent certifications
Professional certifications strengthen your H-1B petition by reinforcing the specialized nature of the role. USCIS evaluates whether the position typically requires a specific bachelor's degree, and credentials like PMP support that case alongside your degree field.
Understand the LCA prevailing wage obligation
Your employer must file a Labor Condition Application certifying you'll be paid at or above the prevailing wage for the role and location. Positions requiring significant travel may complicate LCA filings, so clarify your primary worksite upfront with your employer's immigration team.
Ask about sponsorship policy before accepting interviews
Many employers sponsor selectively based on budget, team headcount, and existing immigration infrastructure. Confirming willingness to sponsor before investing time in a multi-round interview process saves significant effort and avoids last-minute disappointment during the offer stage.
Global Project Manager jobs are hiring across the US. Find yours.
Find Global Project Manager JobsFrequently Asked Questions
Does Global Project Manager qualify as an H-1B specialty occupation?
It can, but approval isn't automatic. USCIS requires the role to normally demand a specific bachelor's degree in a related field, such as business, engineering, or information systems. Generic management roles where any degree qualifies are harder to approve. Your petition is stronger when the job description specifies technical deliverables, cross-functional complexity, and degree requirements tied to the discipline you actually manage.
Which visa types do Global Project Managers most commonly use for U.S. work authorization?
H-1B is the most common path for employer-sponsored roles. L-1B is a strong alternative if you've worked for the same company overseas for at least one continuous year in a specialized knowledge capacity. Australians should also consider the E-3, which has no lottery and shorter processing times. O-1A is possible for applicants with documented extraordinary achievement in program or operations management.
How do I find Global Project Manager jobs that offer visa sponsorship?
Migrate Mate lists visa sponsorship jobs specifically filtered for work authorization needs, so you're not sorting through roles that won't sponsor. Focus your search on large technology, consulting, and infrastructure firms, which file the highest volume of LCAs for project management roles. Filtering by employer size and industry significantly improves your sponsorship hit rate compared to broad searches.
Does my degree field matter for H-1B sponsorship in this role?
Yes, significantly. USCIS looks for a direct relationship between your degree and the specific duties of the role. A degree in project management, business administration, engineering, or information systems typically supports a strong petition. A degree in an unrelated field, even combined with years of experience, can lead to a Request for Evidence or denial unless your attorney can establish a logical connection.
Can Global Project Managers switch employers while on H-1B?
Yes. H-1B portability allows you to start working for a new employer as soon as the new I-129 petition is filed, provided you've maintained valid status and the petition is non-frivolous. Your new employer must file before your current status expires. Premium processing is worth considering if you need a fast decision, since standard processing can take several months.
What is the prevailing wage requirement for sponsored Global Project Manager jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.
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