Manufacturing Specialist Jobs in USA with Visa Sponsorship
Manufacturing Specialist roles qualify for H-1B visa sponsorship when the position requires a bachelor's degree in engineering, industrial technology, or a directly related field. Employers file a Labor Condition Application with DOL before sponsoring, and PERM labor certification is required for the green card path.
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Get Access To All JobsINTRODUCTION
AskBio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular, and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure, limb-girdle muscular dystrophy, multiple system atrophy, Parkinson’s disease, and Pompe disease. AskBio’s gene therapy platform includes Pro10™, an industry-leading proprietary cell line manufacturing process, and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, the company has generated hundreds of proprietary capsids and promoters, several of which have entered pre-clinical and clinical testing.
Our vision: Pioneering science to create transformative molecular medicines.
Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.
Our principles:
- Advance innovative science by pushing boundaries.
- Bring transformative therapeutics to patients in need.
- Provide an environment for employees to reach their fullest potential.
Our values:
- Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
- Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
- Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
- Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
- Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.
Position Summary
The Manufacturing Specialist II, DNA - Preclinical Manufacturing role is responsible for manufacturing and delivering a broad range of research-grade DNA constructs across various production scales to support preclinical research and development activities. The DNA manufactured by the team will support capsid technology development, early product development, intellectual property portfolio, and progression of internal and external early-stage gene therapy programs. This role provides an opportunity to gain industry manufacturing experience while providing opportunities to improve DNA purifications processes.
This role is based onsite in RTP, NC and reports to the Manager, Lab Services and DNA Manufacturing.
JOB RESPONSIBILITIES
- Perform hands-on execution of plasmid purifications to support research grade rAAV manufacturing, technology improvements, and progression of early-stage gene therapy programs.
- Follow batch records and document method procedures in a detailed, organized manner.
- Perform and evaluate data analysis at completion of test method; Summarize results and finalize batch records.
- Independently support process investigations, improvements, and optimization activities in collaboration with Senior Research Associate and DNA Process Development group.
- Identify, develop, and implement process improvements such as revisions to SOPs, Batch Records, Analytical Records, Formulation Records and initiating new procedures, when necessary.
- Inventory management of raw materials and laboratory supplies.
- Prepare manufacturing reports and data to present to scientists and management.
- Ensure lab areas are clean and organized. This includes ensuring equipment, supplies and raw materials are available and ready for use.
MINIMUM REQUIREMENTS
- Bachelor’s degree in a biological or engineering discipline with 2+ years relevant work experience; or Master’s degree in a biological or engineering discipline; or High School Diploma with 6+ years of role relevant work experience
- Experience and/or demonstrated skills with one or more of the following techniques: aseptic technique, making reagents at desired dilutions or concentrations, Restriction Enzyme digest, Gel Electrophoresis, DNA quantitation, identifying annotated features on a plasmid map, bacterial cell culture, centrifugation, filtration, fermentation, and liquid chromatography
- Strong attention to detail, highly organized and the ability to multitask in a fast-paced, highly interactive team environment
- Track record of independently delivering and interpreting experimental results
- Excellent verbal and written communication skills with the ability to maintain formal record keeping and interact effectively with internal/external stakeholders
- Comfortable working and learning in a fast-paced team-oriented laboratory environment
- Experience with lab management, fermentation and molecular biology/DNA sequence design and analysis software
PREFERRED EDUCATION, EXPERIENCE AND SKILLS
- Master’s degree in a biological or engineering discipline
- Experience with fermentation
- Experience with SnapGene
AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job-related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at careers@askbio.com.
Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio, through any medium, will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio, no fee or payment of any kind will be paid to the agency.
INTRODUCTION
AskBio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular, and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure, limb-girdle muscular dystrophy, multiple system atrophy, Parkinson’s disease, and Pompe disease. AskBio’s gene therapy platform includes Pro10™, an industry-leading proprietary cell line manufacturing process, and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, the company has generated hundreds of proprietary capsids and promoters, several of which have entered pre-clinical and clinical testing.
Our vision: Pioneering science to create transformative molecular medicines.
Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.
Our principles:
- Advance innovative science by pushing boundaries.
- Bring transformative therapeutics to patients in need.
- Provide an environment for employees to reach their fullest potential.
Our values:
- Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
- Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
- Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
- Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
- Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.
Position Summary
The Manufacturing Specialist II, DNA - Preclinical Manufacturing role is responsible for manufacturing and delivering a broad range of research-grade DNA constructs across various production scales to support preclinical research and development activities. The DNA manufactured by the team will support capsid technology development, early product development, intellectual property portfolio, and progression of internal and external early-stage gene therapy programs. This role provides an opportunity to gain industry manufacturing experience while providing opportunities to improve DNA purifications processes.
This role is based onsite in RTP, NC and reports to the Manager, Lab Services and DNA Manufacturing.
JOB RESPONSIBILITIES
- Perform hands-on execution of plasmid purifications to support research grade rAAV manufacturing, technology improvements, and progression of early-stage gene therapy programs.
- Follow batch records and document method procedures in a detailed, organized manner.
- Perform and evaluate data analysis at completion of test method; Summarize results and finalize batch records.
- Independently support process investigations, improvements, and optimization activities in collaboration with Senior Research Associate and DNA Process Development group.
- Identify, develop, and implement process improvements such as revisions to SOPs, Batch Records, Analytical Records, Formulation Records and initiating new procedures, when necessary.
- Inventory management of raw materials and laboratory supplies.
- Prepare manufacturing reports and data to present to scientists and management.
- Ensure lab areas are clean and organized. This includes ensuring equipment, supplies and raw materials are available and ready for use.
MINIMUM REQUIREMENTS
- Bachelor’s degree in a biological or engineering discipline with 2+ years relevant work experience; or Master’s degree in a biological or engineering discipline; or High School Diploma with 6+ years of role relevant work experience
- Experience and/or demonstrated skills with one or more of the following techniques: aseptic technique, making reagents at desired dilutions or concentrations, Restriction Enzyme digest, Gel Electrophoresis, DNA quantitation, identifying annotated features on a plasmid map, bacterial cell culture, centrifugation, filtration, fermentation, and liquid chromatography
- Strong attention to detail, highly organized and the ability to multitask in a fast-paced, highly interactive team environment
- Track record of independently delivering and interpreting experimental results
- Excellent verbal and written communication skills with the ability to maintain formal record keeping and interact effectively with internal/external stakeholders
- Comfortable working and learning in a fast-paced team-oriented laboratory environment
- Experience with lab management, fermentation and molecular biology/DNA sequence design and analysis software
PREFERRED EDUCATION, EXPERIENCE AND SKILLS
- Master’s degree in a biological or engineering discipline
- Experience with fermentation
- Experience with SnapGene
AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job-related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at careers@askbio.com.
Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio, through any medium, will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio, no fee or payment of any kind will be paid to the agency.
See all 155+ Manufacturing Specialist Jobs
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Get Access To All JobsTips for Finding Visa Sponsorship as a Manufacturing Specialist
Match your degree to the role
H-1B eligibility hinges on your degree field directly matching the Manufacturing Specialist role. A general business degree won't work if the job spec requires industrial engineering. Pull the O*NET profile for your specific title and confirm the degree alignment before applying.
Target manufacturers with LCA filing history
Aerospace, automotive, and semiconductor manufacturers file Labor Condition Applications regularly for Manufacturing Specialist roles. Search Migrate Mate to find employers with verified LCA sponsorship history filtered by role, so you're applying where active sponsorship already exists.
Verify prevailing wage before negotiating
Your employer's LCA must certify your wage meets DOL's prevailing wage for your location and role level. Use the OFLC Wage Search to look up the wage tier before you negotiate, so your offer clears the DOL threshold and doesn't delay certification.
Flag continuous manufacturing operations in job descriptions
Employers sponsoring H-1B workers in continuous-process manufacturing can argue cap-exempt status if they qualify as a nonprofit research entity, but most don't. Confirm whether your employer is cap-subject early, since the annual cap and selection process directly affects your start-date timeline.
Prepare for PERM before your H-1B expires
PERM labor certification for manufacturing roles requires the employer to run recruitment and document that no qualified U.S. workers applied. This process takes months, so your employer needs to start PERM well before your six-year H-1B maximum to keep your green card timeline on track.
Document hands-on certifications alongside your degree
USCIS adjudicators reviewing Manufacturing Specialist H-1B petitions look for specialty occupation evidence beyond the degree. Lean Six Sigma, CNC programming credentials, or ASQ certifications reinforce that the role requires specialized knowledge, strengthening your petition against a Request for Evidence.
Frequently Asked Questions
Does a Manufacturing Specialist role qualify as a specialty occupation for H-1B?
It depends on how the employer defines the position. USCIS requires that the role normally requires a bachelor's degree in a specific field like industrial engineering, manufacturing engineering, or materials science. Generic production supervisor titles often fail this test. The job description must show that theoretical and practical application of specialized knowledge is required, not just on-the-job training.
Which visa types realistically cover Manufacturing Specialist roles?
H-1B is the primary path for degree-holding manufacturing specialists, covering initial status up to three years and extendable to six. Canadian and Mexican nationals should check whether their specific role appears on the USMCA TN visa profession list. For the green card path, most manufacturing specialists pursue EB-2 or EB-3 through PERM labor certification, which requires the employer to demonstrate no qualified U.S. workers are available.
How do I find employers who actively sponsor Manufacturing Specialist visas?
Browse Migrate Mate to search employers with verified sponsorship history for manufacturing roles. The platform shows companies that have filed LCAs for positions matching your job title, so you can focus your applications where real sponsorship activity exists rather than guessing based on company size or brand name.
Does my engineering degree from outside the U.S. qualify for H-1B sponsorship in this role?
A foreign degree can qualify if it's evaluated as equivalent to a U.S. bachelor's degree in a directly related field. Most three-year engineering degrees from Australia, Canada, the UK, and India are accepted with a credential evaluation from a NACES-member service. USCIS may also accept a combination of a lower-level degree plus substantial specialized work experience in manufacturing engineering if the total is equivalent.
Can an F-1 OPT student work as a Manufacturing Specialist without employer sponsorship?
Yes, during the standard 12-month OPT period your employer doesn't file anything on your behalf. If your degree is in a STEM-designated field like industrial engineering or manufacturing engineering, you can apply for a 24-month STEM OPT extension, but your employer must be enrolled in E-Verify and sign a training plan. The role must directly relate to your degree's CIP classification.
What is the prevailing wage requirement for sponsored Manufacturing Specialist jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.