Chemist Jobs in Massachusetts
Chemist jobs in Massachusetts draw consistent demand across the state's deep pharmaceutical, biotechnology, and materials science sectors, with openings at every level from entry-level lab technician roles through senior research scientist and principal chemist positions. The largest concentrations of hiring are in the Greater Boston area, Cambridge, and Worcester, where established employers such as Pfizer, Thermo Fisher Scientific, and Biogen maintain significant research and manufacturing operations. Analytical chemistry, organic synthesis, and quality control are the most in-demand specialties across both large pharma and contract research organizations throughout the state. Find a role that fits below and apply directly.
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Showing 5 of 18+ Chemist jobs
Overview:
Business Title: Chemist II – RNA Synthesis
Position Title: Analyst II
Division: Consumer Products Services
Entity: Consumer Products Services/ATL
Location: Boston, MA
Reports to: Manager
FLSA: Non-exempt
Hours Worked: Typically, Monday through Friday, forty-hours per week. However, must be flexible to meet the needs of the department and complete other projects as assigned.
Position Summary:
The Chemist II is responsible for assisting with synthesis and downstream processing of oligo synthesis using various analytical techniques. FPLC (Fast Protein Liquid Chromatography, HPLC, LCMS and other analytical instruments are used. This person will work on multiple projects simultaneously and stay current with new modifications of oligonucleotides.
Duties and Responsibilities:
It is everyone’s responsibility to live out our Values and Absolutes by Shaping a World of Trust while ensuring responsible progress.
.
- Synthesis: Assist in the synthesis of oligonucleotides using automated synthesizers, following established protocols, ensuring accuracy in reagent preparation and reaction conditions.
- Purification: Perform purification of oligonucleotides using techniques such as FPLC and HPLC and monitoring purification processes to achieve high quality results.
- Analysis: Conduct analytical assays to verify the quality and identity of synthesized oligonucleotides using LC-MS
- Documentation: Maintain accurate and detailed records of experiments, procedures, and results. Ensure all documentation is compliant with company standards and regulatory requirements.
- Lab Maintenance: Contribute to the maintenance of the laboratory.
- Collaboration: Work closely with senior chemists and other team members to support ongoing projects.
- Use of general laboratory equipment including but not limited to pipettors, centrifuges, incubators, biological safety cabinets and balances
- Familiarity with various statistical analysis tools and able to solve technical problems and make recommendations for improvement
- Work closely with members of the RNAi scale up chemistry team to understand and validate requirements for synthesis scaleup and downstream processing
- Review literature to stay current on new methods for oligonucleotides and provide technical solutions to clients and management
- Software includes instrument-specific for capturing and analyzing data, Microsoft Office (Word, Excel, PowerPoint, Outlook, Teams/Sharepoint, etc), LIMS, electronic laboratory notebooks, etc.
- Detailed record keeping of daily experiments in ELNs
- Identify, troubleshoot, and suggest technical solutions to clients and management
- Follow the guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures.
- Comply with clients’ and Company management systems in accordance with appropriate regulatory agencies.
- Other duties as defined by the Manager, department needs and workload
Skills & Proficiencies:
- Hands on experience in solid phase oligonucleotide synthesis is a plus
- Strong laboratory skills and experience with analytical instrumentation such as AKTA, Agilent LC-MS and UPLC, Vanquish LTQ, Water’s QDA, etc.
- Experience with laboratory techniques and equipment (pipetting, mass spectrometry, chromatography) is required
- Basic understanding of chemistry, stoichiometry and chemical synthesis
- Strong organizational skills and time management skills
- Effective communication skills for collaborating with team members and conveying technical information clearly.
- Strong problem-solving abilities and critical thinking skills
- Ability to organize and prioritize workload to meet or exceed deadlines
- Individual and Team work ethic
- Proficiency with Windows, Word & Excel
- Strong attention to detail and ability to follow protocols precisely
- Positive attitude, self-motivated, high level of engagement
- Eagerness to learn and adapt in a fast paced environment
- Champions and adheres to company values including team engagement
Education and Experience:
- Degree requirement: Bachelor's Degree in Chemistry, Chemical/Biomedical engineering, pharmaceutical sciences or a related field with 1-2 years experience or Master’s degree with 0-1 year experience.
- Experience with oligonucleotides helpful
Compensation Range: $36.00-$40.00 per hour (e.g., the job posting is not necessarily reflective of actual compensation that may be earned, and actual compensation is subject to variation due to such factors as location, education, experience, and skillset).
Overview:
Business Title: Chemist II – RNA Synthesis
Position Title: Analyst II
Division: Consumer Products Services
Entity: Consumer Products Services/ATL
Location: Boston, MA
Reports to: Manager
FLSA: Non-exempt
Hours Worked: Typically, Monday through Friday, forty-hours per week. However, must be flexible to meet the needs of the department and complete other projects as assigned.
Position Summary:
The Chemist II is responsible for assisting with synthesis and downstream processing of oligo synthesis using various analytical techniques. FPLC (Fast Protein Liquid Chromatography, HPLC, LCMS and other analytical instruments are used. This person will work on multiple projects simultaneously and stay current with new modifications of oligonucleotides.
Duties and Responsibilities:
It is everyone’s responsibility to live out our Values and Absolutes by Shaping a World of Trust while ensuring responsible progress.
.
- Synthesis: Assist in the synthesis of oligonucleotides using automated synthesizers, following established protocols, ensuring accuracy in reagent preparation and reaction conditions.
- Purification: Perform purification of oligonucleotides using techniques such as FPLC and HPLC and monitoring purification processes to achieve high quality results.
- Analysis: Conduct analytical assays to verify the quality and identity of synthesized oligonucleotides using LC-MS
- Documentation: Maintain accurate and detailed records of experiments, procedures, and results. Ensure all documentation is compliant with company standards and regulatory requirements.
- Lab Maintenance: Contribute to the maintenance of the laboratory.
- Collaboration: Work closely with senior chemists and other team members to support ongoing projects.
- Use of general laboratory equipment including but not limited to pipettors, centrifuges, incubators, biological safety cabinets and balances
- Familiarity with various statistical analysis tools and able to solve technical problems and make recommendations for improvement
- Work closely with members of the RNAi scale up chemistry team to understand and validate requirements for synthesis scaleup and downstream processing
- Review literature to stay current on new methods for oligonucleotides and provide technical solutions to clients and management
- Software includes instrument-specific for capturing and analyzing data, Microsoft Office (Word, Excel, PowerPoint, Outlook, Teams/Sharepoint, etc), LIMS, electronic laboratory notebooks, etc.
- Detailed record keeping of daily experiments in ELNs
- Identify, troubleshoot, and suggest technical solutions to clients and management
- Follow the guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures.
- Comply with clients’ and Company management systems in accordance with appropriate regulatory agencies.
- Other duties as defined by the Manager, department needs and workload
Skills & Proficiencies:
- Hands on experience in solid phase oligonucleotide synthesis is a plus
- Strong laboratory skills and experience with analytical instrumentation such as AKTA, Agilent LC-MS and UPLC, Vanquish LTQ, Water’s QDA, etc.
- Experience with laboratory techniques and equipment (pipetting, mass spectrometry, chromatography) is required
- Basic understanding of chemistry, stoichiometry and chemical synthesis
- Strong organizational skills and time management skills
- Effective communication skills for collaborating with team members and conveying technical information clearly.
- Strong problem-solving abilities and critical thinking skills
- Ability to organize and prioritize workload to meet or exceed deadlines
- Individual and Team work ethic
- Proficiency with Windows, Word & Excel
- Strong attention to detail and ability to follow protocols precisely
- Positive attitude, self-motivated, high level of engagement
- Eagerness to learn and adapt in a fast paced environment
- Champions and adheres to company values including team engagement
Education and Experience:
- Degree requirement: Bachelor's Degree in Chemistry, Chemical/Biomedical engineering, pharmaceutical sciences or a related field with 1-2 years experience or Master’s degree with 0-1 year experience.
- Experience with oligonucleotides helpful
Compensation Range: $36.00-$40.00 per hour (e.g., the job posting is not necessarily reflective of actual compensation that may be earned, and actual compensation is subject to variation due to such factors as location, education, experience, and skillset).
See All 18 Chemist Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Chemist JobsChemist Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Chemist Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
What Massachusetts Employers Look For
The qualifications that appear most often in chemist jobs across Massachusetts.
- Bachelor's degree in chemistry, biochemistry, or a closely related physical science field
- Hands-on laboratory experience with standard analytical instrumentation such as HPLC and GC-MS
- Familiarity with cGMP or GLP compliance requirements common in Massachusetts pharma and biotech settings
- Proficiency in data analysis software and electronic laboratory notebook systems
- Strong written and verbal communication skills for documenting and presenting experimental findings
- Experience with quality control or assurance procedures in a regulated manufacturing or research environment
Chemist Jobs in Massachusetts: Frequently Asked Questions
How do you become a chemist in Massachusetts?
A bachelor's degree in chemistry or a closely related science is the standard minimum requirement for entry-level chemist roles in Massachusetts, with many research positions requiring a master's or doctoral degree. Massachusetts does not issue a state-specific license for chemists, so hiring is credential-driven rather than licensure-driven. Candidates who earn American Chemical Society certification or gain hands-on lab experience through co-ops at Massachusetts universities and research institutions are consistently more competitive in the local market.
How much do chemists make in Massachusetts?
Chemists in Massachusetts earn a median of about $125,000 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $71,120 for the lowest 10% to over $212,210 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire chemists in Massachusetts?
Employers hiring chemists in Massachusetts right now include SEQENS, QSA Global, and RC, based on current listings on Migrate Mate as of August 2026. Massachusetts's concentration of pharmaceutical manufacturers, contract research organizations, and materials science firms means chemist demand remains active across both large multinationals and specialized mid-size labs throughout the state.
Which Massachusetts cities have the most chemist jobs?
Devens, Boston, and Cambridge account for the largest share of chemist openings in Massachusetts. Greater Boston and Cambridge drive the bulk of demand because of their dense cluster of pharmaceutical headquarters and biotechnology research campuses, while Worcester's growing life sciences corridor and its proximity to major research universities support a steady volume of analytical and quality chemistry roles.
Are there remote chemist jobs in Massachusetts?
Yes, but they're rare. Most chemist work is hands-on and tied to a physical laboratory, so fully remote positions represent a small fraction of openings. About 0% of chemist openings tied to Massachusetts are remote or hybrid as of August 2026, and those tend to concentrate in regulatory affairs, data analysis, and computational chemistry rather than bench or manufacturing roles.
How can I get hired as a chemist in Massachusetts with little or no experience?
The most realistic entry path is an internship or co-op through one of Massachusetts's research universities, as programs at institutions like UMass Amherst, Northeastern, and MIT routinely place students directly into pharma and biotech labs. Large Massachusetts employers such as Thermo Fisher Scientific and contract research organizations regularly hire into quality control technician and lab analyst roles that require only a bachelor's degree and some coursework-based lab experience. Candidates moving from adjacent roles such as laboratory assistant or chemical technician also find these positions accessible, and ACS student membership or certification adds a measurable edge during screening.
Where can I find and apply to chemist jobs in Massachusetts?
You can find and apply to chemist jobs in Massachusetts on Migrate Mate, which lists current openings across the state's pharmaceutical, biotechnology, and materials science sectors. Find roles that fit your experience and specialty and apply directly from the listings.
See All 18 Chemist Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Chemist Jobs