Chief Medical Information Officer Jobs in South Carolina

Chief Medical Information Officer jobs in South Carolina concentrate in health system administration, academic medicine, and integrated care networks, with demand anchored by large hospital groups and regional health authorities across a market that ranks among the more active in the Southeast. Most openings are in Columbia, Charleston, and Greenville, where employers such as Prisma Health, MUSC Health, and Bon Secours have sustained leadership hiring needs. The most in-demand focus areas are clinical informatics strategy, EHR optimization, and population health data governance. See the openings below and apply to the ones that match your experience.

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Overview

Open roles36
Top employerState of South Carolina
Top cityColumbia, SC
Cities hiring14
Work type64% On-site
Top industryBanking

Showing 5 of 36+ Chief Medical Information Officer jobs

Global Lending Services
Vice President, Information Technology
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Global Lending Services
Added 1d ago
Vice President, Information Technology
Global Lending Services
Greenville, South Carolina
Creative & Design
Product Management
UI/UX Design
Hybrid
Master's degree
1,001-5,000

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State of South Carolina
Administrative Assistant (Health Information Services - HIS)
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State of South Carolina
Added 1d ago
Administrative Assistant (Health Information Services - HIS)
State of South Carolina
Richland County, SC
Program Management
Project Management
Quality Assurance & Testing (QA Testing)
$37k - $48k/yr
On-Site
High school diploma or GED
10,000+

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State of South Carolina
Information Security Specialist
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State of South Carolina
Added 1d ago
Information Security Specialist
State of South Carolina
Richland County, SC
Compliance & Risk
Cybersecurity
Security & Protective Services
On-Site
10,000+

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Ryder System
Senior Information Security Operations Center Analyst
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Ryder System
Added 2d ago
Senior Information Security Operations Center Analyst
Ryder System
Columbia, South Carolina
Business Analyst
Data Analytics
$85k - $95k/yr
On-Site
Bachelor's degree in engineering

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Lexington Health
Manager - Information Security
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Lexington Health
Added 2d ago
Manager - Information Security
Lexington Health
West Columbia, South Carolina
Data Analytics
Data Science
Associate's degree
5,001-10,000

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See All 36 Chief Medical Information Officer Jobs in South Carolina

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Chief Medical Information Officer Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
5 jobs
West Columbia
4 jobs
Charleston
3 jobs
Spartanburg
3 jobs
Rock Hill
2 jobs
Greenville
2 jobs
Fountain Inn
2 jobs
North Charleston
2 jobs
Clinton
1 job

Chief Medical Information Officer Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • State of South Carolina
    State of South Carolina10
  • Prisma Health
    Prisma Health3
  • American Credit Acceptance
    American Credit Acceptance3
  • Kyocera AVX
    Kyocera AVX2
  • Boeing
    Boeing1

Top Industries Hiring

  • Banking & Financial Services
  • Healthcare & Medical Services
  • Fintech
  • Government & Public Sector
  • Education

What South Carolina Employers Look For

The qualifications that appear most often in chief medical information officer jobs across South Carolina.

  • Active medical license recognized by the South Carolina Board of Medical Examiners required
  • Board certification in clinical informatics or a related medical specialty strongly preferred
  • Minimum ten years of combined clinical practice and healthcare IT leadership experience
  • Demonstrated experience with enterprise EHR platforms such as Epic or Cerner at scale
  • Graduate degree in health informatics, healthcare administration, or a clinical field required
  • Proven ability to lead cross-functional teams and align clinical and technology stakeholders

Chief Medical Information Officer Jobs in South Carolina: Frequently Asked Questions

How do you become a chief medical information officer in South Carolina?

You must hold an active medical license issued or recognized by the South Carolina Board of Medical Examiners, which requires passing the USMLE steps and completing an accredited residency. Most South Carolina employers also expect board certification in clinical informatics through the American Board of Preventive Medicine or an equivalent pathway. A graduate degree in health informatics or a related field, combined with senior clinical IT leadership experience at a South Carolina health system, is the standard hiring path.

Which companies hire chief medical information officers in South Carolina?

Employers hiring chief medical information officers in South Carolina right now include State of South Carolina, Prisma Health, and American Credit Acceptance, based on current listings on Migrate Mate as of July 2026. South Carolina's largest integrated health systems, academic medical centers, and regional hospital networks account for the majority of these leadership openings.

Which South Carolina cities have the most chief medical information officer jobs?

Columbia, West Columbia, and Lexington County have the most chief medical information officer openings in South Carolina. Columbia's concentration of state government health agencies and Prisma Health's flagship operations, Charleston's academic medical infrastructure anchored by MUSC Health, and Greenville's growing Bon Secours footprint explain why hiring in those metros consistently outpaces the rest of the state.

Are there remote chief medical information officer jobs in South Carolina?

Yes, and more than most clinical roles, since the work centers on strategy, data governance, and vendor oversight rather than direct patient care. About 36% of chief medical information officer openings tied to South Carolina are remote or hybrid as of July 2026, reflecting ongoing flexibility at the executive level. Functions such as EHR policy development, analytics oversight, and vendor negotiations are most commonly performed remotely.

How can I get hired as a chief medical information officer in South Carolina with little or no experience?

The most realistic entry path is moving from a practicing physician or senior clinical IT role into a medical director of informatics position at a South Carolina health system, then building toward the CMIO level. Prisma Health and MUSC Health both staff physician informatics roles that serve as pipelines into executive informatics leadership. Completing the American Board of Preventive Medicine's clinical informatics certification while working in a clinical analyst or physician champion role at a South Carolina hospital gives candidates a measurable edge without prior CMIO experience.

Where can I find and apply to chief medical information officer jobs in South Carolina?

You can find and apply to chief medical information officer jobs in South Carolina on Migrate Mate, which lists current South Carolina openings updated regularly. Search the listings, identify the roles that match your clinical background and informatics experience, and apply directly to the ones that fit.

See All 36 Chief Medical Information Officer Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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