Chief Medical Information Officer Jobs in South Carolina
Chief Medical Information Officer jobs in South Carolina concentrate in health system administration, academic medicine, and integrated care networks, with demand anchored by large hospital groups and regional health authorities across a market that ranks among the more active in the Southeast. Most openings are in Columbia, Charleston, and Greenville, where employers such as Prisma Health, MUSC Health, and Bon Secours have sustained leadership hiring needs. The most in-demand focus areas are clinical informatics strategy, EHR optimization, and population health data governance. See the openings below and apply to the ones that match your experience.
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How will you drive value within the organization as a Vice President, Information Technology?
- Assist the Chief Information Officer in the strategy and planning of information technology assets
- Execute the plans for the technology initiatives and assure that they meet the committed dates for implementation
- Responsible for production operations and system availability of the technology platform on a 7x24x365 basis
- Perform risk assessments of all technology platforms and make recommendations for remediation of any issues
- Responsible for projects and resources that support the voice and data infrastructure
- Train and familiarize IT staff on agile principles of project management and lifecycle
- Assist the Chief Information Officer in the drafting and implementation of technology policies, procedures, and controls
- Responsible for IT compliance with SOC II or SOX controls
- Responsible for maintenance of the corporate network security systems and partners; must be familiar with IDS/IPS technologies as well as Cisco appliances
- Responsible for the vendor management and contract negotiation with IT partners; ability to hold partners accountable to contractual obligations
- Responsible for artifacts and reports required for IT security and process controls
- Mentor and manage technology professionals in various roles related to the support of the GLS technology infrastructure
- Govern the GLS production change review board or CAB
- Prepare monthly reports for issue management and resolution for leadership
- Organize, plan, work on multiple projects, prioritize, and meet deadlines
- Serve as a contributing member of project teams(s), or leader of project team(s), coordinating resources to ensure achievement of project activities as assigned
- Foster a collaborative culture that facilitates the achievement of business plan objectives by working closely with other associates and members of management
- Perform additional assignments as required by the needs of the company or as directed by management
What should you already know to be successful as a Vice President, Information Technology?
- Minimum of bachelor’s degree in Information Systems, Computer Science, or related field required. Master’s degree preferred
- Minimum of twelve (12) years’ experience in various technology roles, including leadership
- Technology management within a financial organization required
- Experience within an environment governed by SOX or SSAE 16 SOC II controls
- Knowledge and experience with cloud concepts as well as SAAS vendors
- ITIL disciplines for delivery and service desk management
- Ability to prepare, present, and articulate information to senior leadership of the organization
- Exceptional analytical and problem-solving skills
- Must be proficient with internetworking technologies and concepts
- Working knowledge of telephony technologies in a premise-based PBX and cloud environment for the support of call center operations
- Ability to work well independently and in a team environment
- Excellent customer service skills with technical and non-technical customers
- Ability to handle sensitive and confidential materials in a professional manner
- Intrinsically motivated with demonstrated ability to take initiative, identify needs, make recommendations for improvement, see recommendations through implementation, and evaluate improvements for effectiveness
- Excellent interpersonal skills: friendly and tactful with the ability to influence others, effectively manage conflict, exercise sound judgment, effectively manage highly sensitive and confidential information, interact at all levels within the organization, and build cross-functional partnerships across the business
- Strong verbal and written communication skills
- Team player that can adapt in a fast pace and changing environment
- Commitment to exemplifying the organizational core values and key competencies
- Demonstrated ability to motivate and lead a team - provide quality training, guidance, performance coaching and feedback to assigned staff
- Excellent organizational skills with high attention to detail and demonstrated ability to effectively set and manage multiple conflicting priorities
- Ability to think strategically and deliver tactically
Physical Requirements: The physical requirements described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made for individuals with disabilities to help perform the essential functions.
- Significant portions of daily assignments involve application of manual skills requiring motor coordination in combination with finger dexterity
- Remain in a stationary position up to 100% of the workday
- Constantly operate a computer and other standard office equipment
- Job functions involve sedentary to light physical effort. Physical demands range from sitting, walking, standing, or pushing or pulling materials. Work may involve exerting up to 10 pounds of force to lift, carry, push, pull, or move objects.
- Be able to perform activities such as: viewing a computer terminal, extensive reading, bending, and kneeling
Work Conditions: The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
- This job operates in a professional office environment, primarily indoors
- The noise level in the work environment is usually moderately quiet
- The position does require travel, up to 10%
Schedule:
- This position is full-time
- This is an exempt level position whereby business need will dictate the exact work schedule which should be expected to vary at times. Generally, days and hours of work are Monday through Friday, 8:00am-6:00pm
- Regular, predictable attendance is required, including overtime hours as business demands dictate
- Evening and weekend work may be required as job duties demand
See All 36 Chief Medical Information Officer Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find JobsChief Medical Information Officer Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Chief Medical Information Officer Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- State of South Carolina10

- Prisma Health3

- American Credit Acceptance3

- Kyocera AVX2

- Boeing1

Top Industries Hiring
- Banking & Financial Services
- Healthcare & Medical Services
- Fintech
- Government & Public Sector
- Education
What South Carolina Employers Look For
The qualifications that appear most often in chief medical information officer jobs across South Carolina.
- Active medical license recognized by the South Carolina Board of Medical Examiners required
- Board certification in clinical informatics or a related medical specialty strongly preferred
- Minimum ten years of combined clinical practice and healthcare IT leadership experience
- Demonstrated experience with enterprise EHR platforms such as Epic or Cerner at scale
- Graduate degree in health informatics, healthcare administration, or a clinical field required
- Proven ability to lead cross-functional teams and align clinical and technology stakeholders
Chief Medical Information Officer Jobs in South Carolina: Frequently Asked Questions
How do you become a chief medical information officer in South Carolina?
You must hold an active medical license issued or recognized by the South Carolina Board of Medical Examiners, which requires passing the USMLE steps and completing an accredited residency. Most South Carolina employers also expect board certification in clinical informatics through the American Board of Preventive Medicine or an equivalent pathway. A graduate degree in health informatics or a related field, combined with senior clinical IT leadership experience at a South Carolina health system, is the standard hiring path.
Which companies hire chief medical information officers in South Carolina?
Employers hiring chief medical information officers in South Carolina right now include State of South Carolina, Prisma Health, and American Credit Acceptance, based on current listings on Migrate Mate as of July 2026. South Carolina's largest integrated health systems, academic medical centers, and regional hospital networks account for the majority of these leadership openings.
Which South Carolina cities have the most chief medical information officer jobs?
Columbia, West Columbia, and Lexington County have the most chief medical information officer openings in South Carolina. Columbia's concentration of state government health agencies and Prisma Health's flagship operations, Charleston's academic medical infrastructure anchored by MUSC Health, and Greenville's growing Bon Secours footprint explain why hiring in those metros consistently outpaces the rest of the state.
Are there remote chief medical information officer jobs in South Carolina?
Yes, and more than most clinical roles, since the work centers on strategy, data governance, and vendor oversight rather than direct patient care. About 36% of chief medical information officer openings tied to South Carolina are remote or hybrid as of July 2026, reflecting ongoing flexibility at the executive level. Functions such as EHR policy development, analytics oversight, and vendor negotiations are most commonly performed remotely.
How can I get hired as a chief medical information officer in South Carolina with little or no experience?
The most realistic entry path is moving from a practicing physician or senior clinical IT role into a medical director of informatics position at a South Carolina health system, then building toward the CMIO level. Prisma Health and MUSC Health both staff physician informatics roles that serve as pipelines into executive informatics leadership. Completing the American Board of Preventive Medicine's clinical informatics certification while working in a clinical analyst or physician champion role at a South Carolina hospital gives candidates a measurable edge without prior CMIO experience.
Where can I find and apply to chief medical information officer jobs in South Carolina?
You can find and apply to chief medical information officer jobs in South Carolina on Migrate Mate, which lists current South Carolina openings updated regularly. Search the listings, identify the roles that match your clinical background and informatics experience, and apply directly to the ones that fit.
See All 36 Chief Medical Information Officer Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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