Clinical Assistant Jobs in North Carolina
Clinical assistant jobs in North Carolina are concentrated in hospital systems, outpatient clinics, and specialty medical practices, with demand at every level from entry-level medical assistants to experienced clinical coordinators. The largest hiring activity is in Charlotte, Raleigh, and Durham, where employers such as Atrium Health, UNC Health, and Duke University Health System maintain a lasting presence and hire clinical assistants across multiple departments. Roles supporting primary care, orthopedics, and behavioral health are among the most consistently posted specialties across the state. See the openings below and apply to the ones that match your experience.
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NC Retina Associates is looking for a Research Assistant to join our team! The research assistant is primarily responsible for assisting in research patient visits according to International Council for Harmonisation Good Clinical Practice (ICH-GCP) guidelines and according to the Institutional Review Board (IRB)-approved study protocol and/or manual of procedures.
Duties:
- Coordinate and schedule subject visits within study/subject specific windows per protocol guidelines.
- Prepare visit-specific documentation and charts for Clinical Research Coordinator.
- Observe Coordinator in patient care and management.
- Assist Coordinator in monitoring subject flow and assist in subject care and management.
- Observe, assist, collect and record all necessary data for follow up (e.g. adverse events, concomitant medications, etc.) study visits (Phase 2 & 3; NO Gene Therapy).
- Transcribe subject study information from source documents to the Electronic Case Report Forms.
- Administer all mandatory questionnaires to study subjects.
- Set up, prepare subject, and conduct electrocardiograms (ECG) on subjects as required per study protocol.
- Promptly request all necessary medical records for Serious Adverse Event Reporting.
- Process and ship laboratory biological samples for analysis.
- Perform intraocular pressure checks after injections.
- Perform trial frame refraction and Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity testing (For Investigator Sponsored Trials (IST)s only, at selected sites).
- Inform subjects and obtain written re-consents in regard to Informed Consent Form (ICF)’s (selected studies)
- Observe and assist scribe in ocular exams for doctors and confirm appropriate treatment per protocol.
- Perform other duties as assigned.
- Obtain any applicable additional/required sponsor training and/or certifications.
Minimum Qualifications:
- High School diploma or the equivalent, with significant relevant experience.
- College degree preferred.
- Ophthalmic experience preferred.
- Effective oral and written communication.
- Delivers safe and appropriate care to patients in addition to the requirements outlined by study protocols.
Pay: $23.00 - $28.00 per hour
Expected hours: 35.0 – 40.0 per week
Benefits:
- 401(k)
- 401(k) matching
- Dental insurance
- Health insurance
- Health savings account
- Life insurance
- Paid time off
- Retirement plan
- Vision insurance
Application Question(s):
- Do you have any Ophthalmology or Retina specific study experience?
- Do you currently reside in North Carolina?
Experience:
- Clinical research: 1 year (Required)
Work Location: In person
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Find Clinical Assistant JobsClinical Assistant Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Clinical Assistant Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
- University of North Carolina at Chapel Hill12
- Advocate Aurora Health5
- East Carolina University5
- Atrium Health4
- Mission Health4
Top Industries Hiring
- Education
- Healthcare & Medical Services
What North Carolina Employers Look For
The qualifications that appear most often in clinical assistant jobs across North Carolina.
- Certified Medical Assistant (CMA) or Registered Medical Assistant (RMA) credential preferred by most North Carolina employers
- High school diploma or GED with completion of an accredited medical assisting program
- Proficiency in electronic health records systems such as Epic or Meditech
- Current CPR and Basic Life Support certification from the American Heart Association
- Experience performing clinical duties including vital signs, phlebotomy, and patient intake
- Strong communication skills and ability to work in a fast-paced North Carolina clinical environment
Clinical Assistant Jobs in North Carolina: Frequently Asked Questions
How do you become a clinical assistant in North Carolina?
North Carolina does not require a state-issued license specifically for clinical assistants, but most employers strongly prefer candidates who hold a nationally recognized credential such as the Certified Medical Assistant (CMA) through the American Association of Medical Assistants or the Registered Medical Assistant (RMA) through American Medical Technologists. Candidates typically complete an accredited medical assisting program at a community college, such as those offered through the North Carolina Community College System, then pass the relevant credentialing exam before applying.
Which companies hire clinical assistants in North Carolina?
Companies currently hiring clinical assistants in North Carolina include University of North Carolina at Chapel Hill, Advocate Aurora Health, and East Carolina University, per current listings on Migrate Mate as of August 2026. North Carolina's large integrated health systems and expanding network of outpatient specialty clinics consistently generate the highest volume of clinical assistant openings across the state.
Which North Carolina cities have the most clinical assistant jobs?
Chapel Hill, Charlotte, and Greenville have the most clinical assistant openings in North Carolina. Charlotte and Raleigh drive the highest volume because of their large hospital systems and dense concentrations of outpatient and specialty clinics, while Durham's openings are anchored by major academic medical institutions that staff clinical support roles across a wide range of departments.
Are there remote clinical assistant jobs in North Carolina?
Yes, but they are rare. Clinical assistant roles are fundamentally hands-on and require in-person patient contact, which limits remote opportunities significantly. About 18% of clinical assistant openings tied to North Carolina are remote or hybrid as of August 2026, and those that exist are typically administrative or care coordination functions that do not involve direct patient care.
How can I get hired as a clinical assistant in North Carolina with little or no experience?
The most realistic entry path is completing a medical assisting program through the North Carolina Community College System, which combines classroom instruction with a required externship that provides supervised clinical hours at local practices. Large North Carolina health systems such as Atrium Health and UNC Health offer new-graduate and entry-level clinical support roles that welcome candidates fresh from externships. Lateral moves from roles like patient care technician, medical receptionist, or phlebotomist are also common ways into clinical assistant positions, and holding a CMA or RMA credential gives candidates a clear edge over uncertified applicants.
Where can I find and apply to clinical assistant jobs in North Carolina?
You can find and apply to clinical assistant jobs in North Carolina on Migrate Mate, which lists current openings from employers across the state. Search the listings to find roles that fit your credentials and experience, then apply directly to the ones that match.
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