Clinical Research Nurse Jobs in North Carolina
Clinical Research Nurse jobs in North Carolina are in strong and consistent demand, concentrated in academic medical centers, pharmaceutical research organizations, and contract research organizations across the state, with openings at every level from entry-level study coordinators to senior principal investigators. The heaviest hiring is in the Research Triangle area, Charlotte, and Winston-Salem, where institutions like Duke Health, UNC Health, and Wake Forest Baptist Health anchor large clinical trial programs. The most sought-after specialties include oncology trials, cardiovascular research, and rare disease studies. Find a role that fits below and apply directly.
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NC Retina Associates is looking for a Research Assistant to join our team! The research assistant is primarily responsible for assisting in research patient visits according to International Council for Harmonisation Good Clinical Practice (ICH-GCP) guidelines and according to the Institutional Review Board (IRB)-approved study protocol and/or manual of procedures.
Duties:
- Coordinate and schedule subject visits within study/subject specific windows per protocol guidelines.
- Prepare visit-specific documentation and charts for Clinical Research Coordinator.
- Observe Coordinator in patient care and management.
- Assist Coordinator in monitoring subject flow and assist in subject care and management.
- Observe, assist, collect and record all necessary data for follow up (e.g. adverse events, concomitant medications, etc.) study visits (Phase 2 & 3; NO Gene Therapy).
- Transcribe subject study information from source documents to the Electronic Case Report Forms.
- Administer all mandatory questionnaires to study subjects.
- Set up, prepare subject, and conduct electrocardiograms (ECG) on subjects as required per study protocol.
- Promptly request all necessary medical records for Serious Adverse Event Reporting.
- Process and ship laboratory biological samples for analysis.
- Perform intraocular pressure checks after injections.
- Perform trial frame refraction and Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity testing (For Investigator Sponsored Trials (IST)s only, at selected sites).
- Inform subjects and obtain written re-consents in regard to Informed Consent Form (ICF)’s (selected studies)
- Observe and assist scribe in ocular exams for doctors and confirm appropriate treatment per protocol.
- Perform other duties as assigned.
- Obtain any applicable additional/required sponsor training and/or certifications.
Minimum Qualifications:
- High School diploma or the equivalent, with significant relevant experience.
- College degree preferred.
- Ophthalmic experience preferred.
- Effective oral and written communication.
- Delivers safe and appropriate care to patients in addition to the requirements outlined by study protocols.
Pay: $23.00 - $28.00 per hour
Expected hours: 35.0 – 40.0 per week
Benefits:
- 401(k)
- 401(k) matching
- Dental insurance
- Health insurance
- Health savings account
- Life insurance
- Paid time off
- Retirement plan
- Vision insurance
Application Question(s):
- Do you have any Ophthalmology or Retina specific study experience?
- Do you currently reside in North Carolina?
Experience:
- Clinical research: 1 year (Required)
Work Location: In person
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Find Clinical Research Nurse JobsClinical Research Nurse Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Clinical Research Nurse Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Science & Research
- Healthcare & Medical Services
- Staffing & Recruiting
- Biotechnology & Pharmaceuticals
- Consulting & Professional Services
What North Carolina Employers Look For
The qualifications that appear most often in clinical research nurse jobs across North Carolina.
- Active registered nurse license issued or recognized by the North Carolina Board of Nursing
- Minimum of one year of clinical nursing experience in an acute care or specialty setting
- Familiarity with Good Clinical Practice guidelines and ICH requirements for clinical trials
- Experience with electronic data capture systems and clinical trial management platforms
- CCRP or CCRC certification preferred or required by many North Carolina research employers
- Strong ability to obtain informed consent and manage protocol compliance for enrolled subjects
Clinical Research Nurse Jobs in North Carolina: Frequently Asked Questions
How do you become a clinical research nurse in North Carolina?
You become a clinical research nurse in North Carolina by first holding an active RN license issued or endorsed by the North Carolina Board of Nursing, which requires passing the NCLEX-RN. Most hiring institutions in the state expect at least a BSN and some clinical bedside experience before moving into research. From there, completing a Good Clinical Practice training course and pursuing CCRP or CCRC certification through the Association of Clinical Research Professionals strengthens your candidacy significantly.
Which companies hire clinical research nurses in North Carolina?
Employers hiring clinical research nurses in North Carolina right now include Thermo Fisher Scientific, University of North Carolina at Chapel Hill, and IQVIA, based on current listings on Migrate Mate as of August 2026. North Carolina's dense network of academic medical centers and pharmaceutical headquarters in the Research Triangle creates year-round openings across both sponsor-side and site-based roles.
Which North Carolina cities have the most clinical research nurse jobs?
Durham, Raleigh, and North Carolina have the most clinical research nurse openings in North Carolina. The Research Triangle concentration in Raleigh, Durham, and Chapel Hill is driven by Duke Health, UNC Health, and the region's pharmaceutical corridor, while Charlotte's openings reflect Atrium Health's large trial portfolio and Winston-Salem's volume traces to Wake Forest Baptist Health's academic research enterprise.
Are there remote clinical research nurse jobs in North Carolina?
Yes, but they're rare. About 46% of clinical research nurse openings tied to North Carolina are remote or hybrid as of August 2026, reflecting the largely hands-on nature of trial nursing, which requires direct subject contact, consent procedures, and on-site protocol assessments. The parts of the role most likely to be remote are data review, regulatory documentation, and sponsor communication for experienced coordinators in decentralized trial models.
How can I get hired as a clinical research nurse in North Carolina with little or no experience?
The most realistic entry path is applying to research coordinator or clinical trial associate roles at North Carolina academic medical centers, which regularly post positions open to nurses with strong bedside skills but no direct research background. Duke Health, UNC Health, and WakeMed run structured onboarding programs that train new staff in Good Clinical Practice and protocol management. Completing a free GCP certification course and gaining experience as a charge nurse or in a specialty unit like oncology or cardiology makes the transition far easier.
Where can I find and apply to clinical research nurse jobs in North Carolina?
You can find and apply to clinical research nurse jobs in North Carolina on Migrate Mate, which lists current openings from employers actively hiring across the state. Find roles that fit your experience and apply directly.
See All 58 Clinical Research Nurse Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
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