Clinical Research Nurse Jobs in Texas
Clinical Research Nurse jobs in Texas are among the most active in the country, concentrated in academic medical centers, pharmaceutical research organizations, and large hospital-affiliated trial units, with openings at every level from entry-level coordinators through senior and principal investigator-support roles. Houston, Dallas, and San Antonio are the primary hiring hubs, anchored by institutions and organizations such as MD Anderson Cancer Center, UT Southwestern Medical Center, and ICON plc, all of which maintain substantial clinical trial operations in Texas. Oncology, cardiovascular research, and neurology trials represent the most consistent demand for clinical research nurses in the state. Find a role that fits below and apply directly.
Find Clinical Research Nurse JobsOverview
Showing 5 of 190+ Clinical Research Nurse jobs
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the No. 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you’ll discover a culture of teamwork, professionalism, and a rewarding career!
JOB SUMMARY
Works under the direction of an Investigator(s) with general supervision, to provide ongoing data management for local and national research studies and may coordinate observational (non-treatment/treatment) trials/studies. May provide supporting role for more complex studies under the direction of the PI, Clinical Research Coordinator and/or Clinical Research Lead.
BENEFITS
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
- PPO medical plan, available day one at no cost for full-time employee-only coverage
- 100% coverage for preventive healthcare-no copay
- Paid Time Off, available day one
- Retirement Programs through the Teacher Retirement System of Texas (TRS)
- Paid Parental Leave Benefit
- Wellness programs
- Tuition Reimbursement
- Public Service Loan Forgiveness (PSLF) Qualified Employer
EXPERIENCE AND EDUCATION
Required
- Education
High School Diploma or
Associate’s Degree in medical or science related field or
Bachelor’s Degree medical or science related field and no prior experience
- Experience
2 years experience with High School Diploma or
1 year experience with Associate’s Degree
Preferred
- Licenses and Certifications
(BLS) BASIC LIFE SUPPORT may be required based on affiliate location requirements.
(CPRAED) CPR AED may be required based on affiliate location requirements.
JOB DUTIES
- Understands visit schedules, criteria and protocol requirements for low complexity trials (e.g., questionnaire, data registry, scripted); schedules research visits.
- Assists research staff by completing research protocol related tasks.
- Reviews and abstracts information from medical records including eligibility criteria.
- Enters data into case report forms or other data collection system based on research study. Assists with maintenance of study level documentation.
- Assists with data queries and possible edits for accuracy.
- Compiles data for regulatory requirements and /or deadlines for local or sponsor submissions.
- Maintains existing databases and ensures data integrity.
- Performs QA/QC clinical analysis and data checks using various databases based on trial.
- Assists with preparing annual reports and/or modifications to institutional review board (IRB). This may include reportable events (UPIRSO).
- Assist and prepare research records for formal sponsor audits or internal audits.
- Recruits and enrolls patients in research study that may include consenting patients after training and with supervision.
- With adequate training and supervision, assists with participant screening and recruitment for more complex trials.
- Conducts and documents consent for participants in studies. Assists with the development of consent plans and documents for participants.
- Identifies incomplete, inaccurate, or missing data for more complex studies and works with lead coordinator to correct errors.
- Assists with ordering and maintaining research supplies following university/department procedures, ensuring that equipment is in good working order.
- With adequate training and supervision, assists with collecting and processing specimens following established procedures/protocols.
- Assists in preparing studies for closeout, (e.g. packing files, documenting files for storage, shipping extra supplies back to sponsor).
- With adequate training/credentialing and supervision, performs study procedures such as phlebotomy, vital signs, and EKG’s needed for research study. Based on research study, other procedures/equipment/services may be required.
- May perform patient care (basic skills) under the direction of PI following scope of work document.
- Duties performed may include one or more of the following core functions: a) Directly interacting with or caring for patients; b) Directly interacting with or caring for human-subjects research participants; c) Regularly maintaining, modifying, releasing or similarly affecting patient records (including patient financial records); or d) Regularly maintaining, modifying, releasing or similarly affecting human-subjects research records.
- Performs other duties as assigned.
- Knowledge of applicable Federal and institutional regulations governing clinical research.
- Knowledge of clinical research protocols.
- Effective organizational skills and attention to detail.
- Proactively works to maximize results of the team and organization.
- Follows and understands the regulations for Protected Health Information (PHI).
- Proactively works to maximize results of the team and organization.
- Possess strong computer skills (spreadsheets, databases, and interactive web-based software).
- Possess good communication skills.
- Possess the ability to problem solve.
- Work requires ability to conduct interviews with research subjects.
- Clinical Setting
- Office Setting
Salary Information
Salary is commensurate with education, skills, and relevant experience.
SECURITY AND EEO STATEMENT
Security
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.
EEO
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the No. 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you’ll discover a culture of teamwork, professionalism, and a rewarding career!
JOB SUMMARY
Works under the direction of an Investigator(s) with general supervision, to provide ongoing data management for local and national research studies and may coordinate observational (non-treatment/treatment) trials/studies. May provide supporting role for more complex studies under the direction of the PI, Clinical Research Coordinator and/or Clinical Research Lead.
BENEFITS
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
- PPO medical plan, available day one at no cost for full-time employee-only coverage
- 100% coverage for preventive healthcare-no copay
- Paid Time Off, available day one
- Retirement Programs through the Teacher Retirement System of Texas (TRS)
- Paid Parental Leave Benefit
- Wellness programs
- Tuition Reimbursement
- Public Service Loan Forgiveness (PSLF) Qualified Employer
EXPERIENCE AND EDUCATION
Required
- Education
High School Diploma or
Associate’s Degree in medical or science related field or
Bachelor’s Degree medical or science related field and no prior experience
- Experience
2 years experience with High School Diploma or
1 year experience with Associate’s Degree
Preferred
- Licenses and Certifications
(BLS) BASIC LIFE SUPPORT may be required based on affiliate location requirements.
(CPRAED) CPR AED may be required based on affiliate location requirements.
JOB DUTIES
- Understands visit schedules, criteria and protocol requirements for low complexity trials (e.g., questionnaire, data registry, scripted); schedules research visits.
- Assists research staff by completing research protocol related tasks.
- Reviews and abstracts information from medical records including eligibility criteria.
- Enters data into case report forms or other data collection system based on research study. Assists with maintenance of study level documentation.
- Assists with data queries and possible edits for accuracy.
- Compiles data for regulatory requirements and /or deadlines for local or sponsor submissions.
- Maintains existing databases and ensures data integrity.
- Performs QA/QC clinical analysis and data checks using various databases based on trial.
- Assists with preparing annual reports and/or modifications to institutional review board (IRB). This may include reportable events (UPIRSO).
- Assist and prepare research records for formal sponsor audits or internal audits.
- Recruits and enrolls patients in research study that may include consenting patients after training and with supervision.
- With adequate training and supervision, assists with participant screening and recruitment for more complex trials.
- Conducts and documents consent for participants in studies. Assists with the development of consent plans and documents for participants.
- Identifies incomplete, inaccurate, or missing data for more complex studies and works with lead coordinator to correct errors.
- Assists with ordering and maintaining research supplies following university/department procedures, ensuring that equipment is in good working order.
- With adequate training and supervision, assists with collecting and processing specimens following established procedures/protocols.
- Assists in preparing studies for closeout, (e.g. packing files, documenting files for storage, shipping extra supplies back to sponsor).
- With adequate training/credentialing and supervision, performs study procedures such as phlebotomy, vital signs, and EKG’s needed for research study. Based on research study, other procedures/equipment/services may be required.
- May perform patient care (basic skills) under the direction of PI following scope of work document.
- Duties performed may include one or more of the following core functions: a) Directly interacting with or caring for patients; b) Directly interacting with or caring for human-subjects research participants; c) Regularly maintaining, modifying, releasing or similarly affecting patient records (including patient financial records); or d) Regularly maintaining, modifying, releasing or similarly affecting human-subjects research records.
- Performs other duties as assigned.
- Knowledge of applicable Federal and institutional regulations governing clinical research.
- Knowledge of clinical research protocols.
- Effective organizational skills and attention to detail.
- Proactively works to maximize results of the team and organization.
- Follows and understands the regulations for Protected Health Information (PHI).
- Proactively works to maximize results of the team and organization.
- Possess strong computer skills (spreadsheets, databases, and interactive web-based software).
- Possess good communication skills.
- Possess the ability to problem solve.
- Work requires ability to conduct interviews with research subjects.
- Clinical Setting
- Office Setting
Salary Information
Salary is commensurate with education, skills, and relevant experience.
SECURITY AND EEO STATEMENT
Security
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.
EEO
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
See All 190+ Clinical Research Nurse Jobs in Texas
Find roles in Texas that match your experience and apply in just a few clicks.
Find Clinical Research Nurse JobsClinical Research Nurse Jobs by City in Texas
Where Texas roles are concentrated, by current openings.
Clinical Research Nurse Job Market in Texas
A snapshot from current Texas openings, updated as new roles post.
Who's Hiring
- UT Southwestern Medical Center17
- Iterative Health15
- UT Health Science Center at San Antonio8
- Fortrea6
- Houston Methodist6
Top Industries Hiring
- Education11
- Healthcare & Medical Services8
- Science & Research3
- Biotechnology & Pharmaceuticals2
- Agriculture & Farming1
What Texas Employers Look For
The qualifications that appear most often in clinical research nurse jobs across Texas.
- Active Registered Nurse license issued or recognized by the Texas Board of Nursing
- Minimum two years of clinical nursing experience in a hospital or research setting
- Experience with GCP guidelines and human subjects research protocols
- CCRP or CCRC certification from the Society of Clinical Research Associates preferred
- Proficiency in electronic data capture systems such as Medidata Rave or REDCap
- Strong working knowledge of FDA regulations governing clinical trial conduct
Clinical Research Nurse Jobs in Texas: Frequently Asked Questions
How do you become a clinical research nurse in Texas?
You need an active Registered Nurse license from the Texas Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN exam. From there, most Texas employers expect at least one to two years of bedside or clinical experience before moving into research. Pursuing certification through the Society of Clinical Research Associates, such as the CCRP credential, strengthens your application and is often required by major research institutions and contract research organizations in Texas.
Which companies hire clinical research nurses in Texas?
Employers hiring clinical research nurses in Texas right now include UT Southwestern Medical Center, Iterative Health, and UT Health Science Center at San Antonio, based on current listings on Migrate Mate as of October 2026. Texas's deep concentration of academic medical systems, contract research organizations, and pharmaceutical trial sites means consistent hiring activity throughout the year, particularly in the Houston and Dallas metro areas.
Which Texas cities have the most clinical research nurse jobs?
Dallas, Houston, and San Antonio have the most clinical research nurse openings in Texas. Houston leads because of its exceptional density of cancer, cardiovascular, and rare disease trial activity anchored by institutions like MD Anderson and Texas Medical Center affiliates, while Dallas benefits from UT Southwestern and a large network of CRO offices, and San Antonio draws from its military medicine research infrastructure and UTHSCSA-affiliated programs.
Are there remote clinical research nurse jobs in Texas?
Yes, but they're rare. Clinical research nursing is largely hands-on, requiring direct patient contact, specimen handling, and on-site protocol adherence, so most roles are facility-based. About 29% of clinical research nurse openings tied to Texas are remote or hybrid as of October 2026, and those positions tend to involve study coordination tasks such as data entry, regulatory document management, and participant follow-up calls rather than direct patient care.
How can I get hired as a clinical research nurse in Texas with little or no experience?
The most realistic entry path is applying for a clinical research coordinator or clinical trials nurse associate role at a large Texas academic medical center, where prior bedside nursing experience substitutes for direct research background. MD Anderson Cancer Center and UT Southwestern both run structured onboarding programs that train new research nurses in GCP and protocol adherence. Nurses transitioning from oncology, cardiology, or ICU units are frequently favored because those clinical backgrounds map directly to the most active trial areas in Texas.
Where can I find and apply to clinical research nurse jobs in Texas?
You can find and apply to clinical research nurse jobs in Texas on Migrate Mate, which lists current openings across the state. Find roles that match your experience and specialty and apply directly to the ones that fit.
See All 190+ Clinical Research Nurse Jobs in Texas
Find roles in Texas that match your experience and apply in just a few clicks.
Find Clinical Research Nurse Jobs