Clinical Research Nurse Jobs in Pennsylvania
Clinical Research Nurse jobs in Pennsylvania are consistently active, with demand concentrated in academic medical centers, pharmaceutical and biotech companies, and large integrated health systems across a range from entry-level research coordinators to senior clinical research nurses and lead investigators. Philadelphia, Pittsburgh, and the Philadelphia suburbs along the Route 202 corridor are the dominant hiring hubs, anchored by institutions like Penn Medicine, UPMC, and Merck. The most sought-after specialties include oncology trials, cardiovascular research, and infectious disease studies. Find a role that fits below and apply directly.
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Showing 5 of 97+ Clinical Research Nurse jobs
Education
Bachelor's Degree Required or
Combination of relevant education and experience may be considered in lieu of degree experience in related clinical research role Required
Experience
2 years experience in related clinical research role Required
See All 97 Clinical Research Nurse Jobs in Pennsylvania
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Find Clinical Research Nurse JobsClinical Research Nurse Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Clinical Research Nurse Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring
- University of Pennsylvania17
- University of Pittsburgh14
- Thomas Jefferson University & Jefferson Health14
- Penn State Health5
- Temple Health4T
Top Industries Hiring
- Healthcare & Medical Services11
- Education4
- Agriculture & Farming1
- Biotechnology & Pharmaceuticals1
What Pennsylvania Employers Look For
The qualifications that appear most often in clinical research nurse jobs across Pennsylvania.
- Active Pennsylvania RN license issued by the Pennsylvania State Board of Nursing
- Prior experience with clinical trial protocols, GCP guidelines, and ICH standards
- Proficiency in electronic data capture systems such as Medidata Rave or REDCap
- CCRP or CCRC certification from the Society of Clinical Research Associates preferred
- Strong understanding of FDA regulations, IRB processes, and informed consent procedures
- Bachelor of Science in Nursing with coursework or experience in research methodology
Clinical Research Nurse Jobs in Pennsylvania: Frequently Asked Questions
How do you become a clinical research nurse in Pennsylvania?
You must first hold an active registered nurse license issued by the Pennsylvania State Board of Nursing, which requires passing the NCLEX-RN. Most employers in Pennsylvania also expect a Bachelor of Science in Nursing. From there, entry into clinical research typically comes through a coordinator role at a hospital, academic medical center, or pharmaceutical site, with credentials like the CCRP certification strengthening your candidacy considerably.
Which companies hire clinical research nurses in Pennsylvania?
Employers hiring clinical research nurses in Pennsylvania right now include University of Pennsylvania, University of Pittsburgh, and Thomas Jefferson University & Jefferson Health, based on current listings on Migrate Mate as of October 2026. Pennsylvania's dense concentration of academic health systems and pharmaceutical headquarters along the I-76 and Route 202 corridors means openings appear regularly across both large institutions and mid-size contract research organizations.
Which Pennsylvania cities have the most clinical research nurse jobs?
Philadelphia, Pittsburgh, and Hershey account for the most clinical research nurse openings in Pennsylvania. Philadelphia leads because of its cluster of academic medical centers, NCI-designated cancer centers, and pharmaceutical companies based in the surrounding suburbs, while Pittsburgh's strength in university-affiliated research at institutions like UPMC drives steady demand in the western part of the state.
Are there remote clinical research nurse jobs in Pennsylvania?
Yes, but they're rare. About 59% of clinical research nurse openings tied to Pennsylvania are remote or hybrid as of October 2026, reflecting that most trial work requires direct patient contact, specimen handling, and on-site protocol compliance. The portions of the role most likely to be performed remotely include data entry, regulatory document management, and sponsor communication for decentralized or virtual trial components.
How can I get hired as a clinical research nurse in Pennsylvania with little or no experience?
The most realistic entry path is applying for a clinical research coordinator role at a Pennsylvania academic medical center or hospital-based research office, where employers like Penn Medicine and UPMC run structured new-grad programs and research training rotations. Nurses transitioning from oncology, cardiology, or ICU units have a strong advantage because protocol adherence and assessment skills transfer directly. Completing a Good Clinical Practice certification before applying signals research readiness and gives you a concrete edge over other applicants without trial experience.
Where can I find and apply to clinical research nurse jobs in Pennsylvania?
You can find and apply to clinical research nurse jobs in Pennsylvania on Migrate Mate, which lists current openings across the state. Search the listings, find roles that match your experience and location, and apply directly.
See All 97 Clinical Research Nurse Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Clinical Research Nurse Jobs