Clinical Research Nurse Jobs in Pennsylvania
Clinical Research Nurse jobs in Pennsylvania are open across Hershey, Philadelphia, and Bryn Mawr and other Pennsylvania metros, with employers like Penn State Health, Thomas Jefferson University & Jefferson Health, and Geisinger hiring at every experience level. Find a role that fits below and apply directly.
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Could you be our next Clinical Research Nurse I at Lankenau Medical Center/ LIMR?
Why work as a Clinical Research Nurse 1 at Main Line Health?
Make an Impact!
The Clinical Research Nurse I will manage and oversee the day-to-day activities of Phase I-IV clinical research studies, industry trials and grant supported research in accordance with Good Clinical Practice (GCP). Daily tasks may include performing basic nursing skills, study coordination with a central focus on managing subject recruitment and enrollment, consistency of study implementation, data management and integrity, and compliance with regulatory requirements and reporting. The Clinical Research Nurse I coordinates procedures, tests and follow-up visits according to the protocol, provides education to research subjects and staff regarding the investigational study, and promotes patient safety for all research related activities working collaboratively with the physician investigators and a multi-disciplinary team.
Join the Team!
Like our patients, the Main Line Health Family encompasses a wide range of backgrounds and abilities. Just as each of our patients requires a personalized care plan, each of our employees, physicians, and volunteers, bring distinctive talents to Main Line Health. Regardless of our unique design, we all share a purpose: providing superior service and care.
Position-Specific Benefits include:
This position is eligible for up to 160 hours of paid time off per year. We also offer a number of employee discounts to various activities, services, and vendors... And employee parking is always free!
Position:
Clinical Research Nurse 1 - Oncology experience preferred.
Shift:
Day Shift - 40 hours/week Monday-Friday 8am-4:30pm
Experience:
0-2 years nursing experience. Clinical research and/or nursing research experience preferred. Clinical research conducted while in the student environment may be considered on a case-by-case basis. Leadership experience in research or healthcare/health care setting preferred.
Education:
A current PA RN license if primary state of residence in PA; if live out of PA, a multi-state license verified in one of the approved states through the Nursing Licensure Compact (effective 9/5/23).
See All 14 Clinical Research Nurse Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Clinical Research Nurse JobsClinical Research Nurse Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Clinical Research Nurse Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring
- Penn State Health4

- Thomas Jefferson University & Jefferson Health3

- Geisinger1

- Guthrie1

- Johnson & Johnson1

Top Industries Hiring
- Healthcare & Medical Services10
- Education2
- Biotechnology & Pharmaceuticals1
- Medical Devices1
- Science & Research1
What Pennsylvania Employers Look For
The qualifications that appear most often in clinical research nurse jobs across Pennsylvania.
- Active RN license in the state of employment
- Minimum two years of clinical nursing experience in a relevant specialty
- Working knowledge of ICH-GCP guidelines and Good Clinical Practice standards
- Experience with electronic data capture systems such as Medidata Rave or REDCap
- CCRP or CCRC certification preferred or required by many employers
- Ability to obtain and maintain site-specific training and protocol certifications
Clinical Research Nurse Jobs in Pennsylvania: Frequently Asked Questions
How many clinical research nurse jobs are there in Pennsylvania?
There are 14+ clinical research nurse openings in Pennsylvania on Migrate Mate as of June 2026, with the most roles in Hershey, Philadelphia, and Bryn Mawr. New positions post regularly as employers across Pennsylvania hire.
Which Pennsylvania cities have the most clinical research nurse jobs?
Hershey, Philadelphia, and Bryn Mawr have the most clinical research nurse openings in Pennsylvania right now, with additional roles spread across smaller metros statewide.
Which companies hire clinical research nurses in Pennsylvania?
Employers hiring clinical research nurses in Pennsylvania include Penn State Health, Thomas Jefferson University & Jefferson Health, and Geisinger, based on current listings on Migrate Mate as of June 2026.
Are there remote clinical research nurse jobs in Pennsylvania?
Yes. About 7% of clinical research nurse openings tied to Pennsylvania are remote or hybrid as of June 2026. The rest are on-site roles based in Pennsylvania metros.
How do I apply for clinical research nurse jobs in Pennsylvania?
You can apply to clinical research nurse jobs in Pennsylvania directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Pennsylvania location, then apply to each one that fits.
See All 14 Clinical Research Nurse Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Clinical Research Nurse Jobs