Clinical Research Nurse Jobs in Massachusetts
Clinical Research Nurse jobs in Massachusetts are among the most active in the country, concentrated in academic medical centers, pharmaceutical sponsors, and contract research organizations, with openings at every level from entry-level research coordinator nurses through senior principal investigators. Boston, Cambridge, and Worcester anchor the majority of hiring, where institutions like Mass General Brigham, Dana-Farber Cancer Institute, and Pfizer's Cambridge operations regularly seek clinical research nurses. The most in-demand specialties are oncology trials, rare disease studies, and early-phase Phase I and II protocol work. Find a role that fits below and apply directly.
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Showing 5 of 118+ Clinical Research Nurse jobs
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
The CRC I will work under the supervision of the Principal Investigator and will participate in tasks related to all phases of the clinical research including the initiation, monitoring, completion, and reporting phases. All activities will be conducted in accordance with Standard Operating Procedures (SOP) and Good Clinical Practices (GCP) Guidelines.
Summary
Following established policies, procedures, and study protocols, provides assistance on clinical research studies, including recruiting, evaluating, and consenting patients for studies; collecting and organizing patient data; scheduling patients for study visits; performing clinical tests such as phlebotomy, EKGs, etc.; and maintaining and updating data generated by the study. Candidates who are in the process of completing their bachelor's degree have a six-month grace period from their hire date (up to one year if starting on a per diem basis) to provide degree equivalency verification.
Does this position require Patient Care?
No
Essential Functions
- Reviews proposals for compliance with sponsor and organizational guidelines; verifies that all sponsor requirements are met.
- Recruiting patients for clinical research studies and conducting phone interviews.
- Monitor participant enrollment, study progress, and protocol compliance, escalating concerns to investigators as appropriate.
- Verifies the accuracy of study forms and updates them per protocol.
- Prepares data for analysis and data entry.
- Maintain study databases and electronic data capture systems, ensuring data accuracy, completeness, and timely entry.
- Documents patient visits and procedures.
- Assists with regulatory binders and QA/QC Procedures.
- Assists with interviewing study subjects.
- Assists with study regulatory submissions.
- Coordinate communication among investigators, study staff, sponsors, and collaborator to support successful study execution.
- Support the preparation of abstracts, presentations, manuscripts, and progress reports related to Williams syndrome and other neurodevelopmental research projects.
Qualifications
Bachelor's Degree required
Experience
Some relevant research project work 0-1 year preferred
Knowledge, Skills and Abilities
- Careful attention to detail and good organizational skills.
- Ability to follow directions.
- Good interpersonal and communication skills.
- Computer literacy.
- Working knowledge of clinical research protocols.
- Ability to demonstrate respect and professionalism for subjects' rights and individual needs.
Additional Job Details (if applicable)
The ideal candidate is a proactive, highly organized, and passionate about advancing research in neurodevelopmental and genetic conditions. Strong interpersonal skills, the ability to work effectively with children, adults, and families, and attention to detail are essential. Candidates should be comfortable balancing participant-facing interactions with data management, regulatory, and administrative responsibilities. The successful candidate will be comfortable working independently to manage study activities while communicating effectively with participants, investigators, and research team members to ensure smooth study operations.
This role provides a unique opportunity to gain hands-on experience in clinical research within a multidisciplinary academic medical center and is well suited for individuals interested in careers in medicine, psychology, neuroscience, genetic counseling, public health, or clinical research. Due to the substantial investment in training and the duration of the research studies, candidates able to commit to the position for at least two years are strongly preferred.
In addition to a resume/CV, strong candidates should provide a cover letter highlighting their interest in the position, relevant experiences, and how this opportunity aligns with their professional and academic goals.
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
Pay Range
Grade
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
The CRC I will work under the supervision of the Principal Investigator and will participate in tasks related to all phases of the clinical research including the initiation, monitoring, completion, and reporting phases. All activities will be conducted in accordance with Standard Operating Procedures (SOP) and Good Clinical Practices (GCP) Guidelines.
Summary
Following established policies, procedures, and study protocols, provides assistance on clinical research studies, including recruiting, evaluating, and consenting patients for studies; collecting and organizing patient data; scheduling patients for study visits; performing clinical tests such as phlebotomy, EKGs, etc.; and maintaining and updating data generated by the study. Candidates who are in the process of completing their bachelor's degree have a six-month grace period from their hire date (up to one year if starting on a per diem basis) to provide degree equivalency verification.
Does this position require Patient Care?
No
Essential Functions
- Reviews proposals for compliance with sponsor and organizational guidelines; verifies that all sponsor requirements are met.
- Recruiting patients for clinical research studies and conducting phone interviews.
- Monitor participant enrollment, study progress, and protocol compliance, escalating concerns to investigators as appropriate.
- Verifies the accuracy of study forms and updates them per protocol.
- Prepares data for analysis and data entry.
- Maintain study databases and electronic data capture systems, ensuring data accuracy, completeness, and timely entry.
- Documents patient visits and procedures.
- Assists with regulatory binders and QA/QC Procedures.
- Assists with interviewing study subjects.
- Assists with study regulatory submissions.
- Coordinate communication among investigators, study staff, sponsors, and collaborator to support successful study execution.
- Support the preparation of abstracts, presentations, manuscripts, and progress reports related to Williams syndrome and other neurodevelopmental research projects.
Qualifications
Bachelor's Degree required
Experience
Some relevant research project work 0-1 year preferred
Knowledge, Skills and Abilities
- Careful attention to detail and good organizational skills.
- Ability to follow directions.
- Good interpersonal and communication skills.
- Computer literacy.
- Working knowledge of clinical research protocols.
- Ability to demonstrate respect and professionalism for subjects' rights and individual needs.
Additional Job Details (if applicable)
The ideal candidate is a proactive, highly organized, and passionate about advancing research in neurodevelopmental and genetic conditions. Strong interpersonal skills, the ability to work effectively with children, adults, and families, and attention to detail are essential. Candidates should be comfortable balancing participant-facing interactions with data management, regulatory, and administrative responsibilities. The successful candidate will be comfortable working independently to manage study activities while communicating effectively with participants, investigators, and research team members to ensure smooth study operations.
This role provides a unique opportunity to gain hands-on experience in clinical research within a multidisciplinary academic medical center and is well suited for individuals interested in careers in medicine, psychology, neuroscience, genetic counseling, public health, or clinical research. Due to the substantial investment in training and the duration of the research studies, candidates able to commit to the position for at least two years are strongly preferred.
In addition to a resume/CV, strong candidates should provide a cover letter highlighting their interest in the position, relevant experiences, and how this opportunity aligns with their professional and academic goals.
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
Pay Range
Grade
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
See All 118+ Clinical Research Nurse Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Clinical Research Nurse JobsClinical Research Nurse Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Clinical Research Nurse Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
- Massachusetts General Hospital22
- Dana-Farber Cancer Institute13
- Brigham and Women's Hospital9
- Beth Israel Lahey Health8
- Alira Health6
Top Industries Hiring
- Biotechnology & Pharmaceuticals11
- Healthcare & Medical Services9
- Staffing & Recruiting1
- Consulting & Professional Services1
What Massachusetts Employers Look For
The qualifications that appear most often in clinical research nurse jobs across Massachusetts.
- Active Massachusetts Registered Nurse license issued by the Massachusetts Board of Registration in Nursing
- Minimum two years of clinical nursing experience in a hospital or patient-care setting
- Experience with clinical trial protocols and Good Clinical Practice guidelines
- Certified Clinical Research Professional or Certified Clinical Research Coordinator credential preferred
- Proficiency with electronic data capture systems such as REDCap, Medidata, or similar platforms
- Strong knowledge of FDA regulations and IRB submission and approval processes
Clinical Research Nurse Jobs in Massachusetts: Frequently Asked Questions
How do you become a clinical research nurse in Massachusetts?
You must hold an active Registered Nurse license issued by the Massachusetts Board of Registration in Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN exam. Most Massachusetts employers also expect at least two years of direct patient care experience before moving into research. Earning a credential such as the Certified Clinical Research Professional strengthens your application considerably and is often preferred by academic medical centers and pharmaceutical sponsors in the state.
Which companies hire clinical research nurses in Massachusetts?
Employers hiring clinical research nurses in Massachusetts right now include Massachusetts General Hospital, Dana-Farber Cancer Institute, and Brigham and Women's Hospital, based on current listings on Migrate Mate as of October 2026. Massachusetts's density of academic health systems, global pharmaceutical headquarters, and contract research organizations means consistent, year-round demand across the state.
Which Massachusetts cities have the most clinical research nurse jobs?
Boston, Brookline, and Cambridge have the most clinical research nurse openings in Massachusetts. Boston and Cambridge dominate because of their concentration of teaching hospitals, biotech campuses, and pharmaceutical sponsors, while Worcester draws steady demand from UMass Memorial Health and its affiliated research programs.
Are there remote clinical research nurse jobs in Massachusetts?
Yes, but they're rare. Clinical research nursing is primarily a hands-on, site-based role requiring direct patient contact, protocol assessments, and on-site monitoring. About 65% of clinical research nurse openings tied to Massachusetts are remote or hybrid as of October 2026, and those positions typically cover data review, regulatory document management, or remote patient monitoring within decentralized trial designs.
How can I get hired as a clinical research nurse in Massachusetts with little or no experience?
The most realistic entry path is applying for a clinical research coordinator or research associate nurse role at one of Massachusetts's large academic health systems, which regularly post positions open to nurses with bedside experience but no prior trial background. Mass General Brigham, Boston Medical Center, and Dana-Farber Cancer Institute all run structured onboarding and training programs for research staff new to clinical trials. Completing a Good Clinical Practice certification course and volunteering with an IRB committee or quality-improvement project adds concrete credibility to applications.
Where can I find and apply to clinical research nurse jobs in Massachusetts?
You can find and apply to clinical research nurse jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings. Find roles that fit your experience and location and apply directly to the employer through each listing.
See All 118+ Clinical Research Nurse Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Clinical Research Nurse Jobs