Clinical Research Nurse Jobs in Massachusetts

Clinical Research Nurse jobs in Massachusetts are among the most active in the country, concentrated in academic medical centers, pharmaceutical sponsors, and contract research organizations, with openings at every level from entry-level research coordinator nurses through senior principal investigators. Boston, Cambridge, and Worcester anchor the majority of hiring, where institutions like Mass General Brigham, Dana-Farber Cancer Institute, and Pfizer's Cambridge operations regularly seek clinical research nurses. The most in-demand specialties are oncology trials, rare disease studies, and early-phase Phase I and II protocol work. Find a role that fits below and apply directly.

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Overview

Open roles136+
Top employerDana-Farber Cancer Institute
Top cityBoston, MA
Cities hiring25
Work type50% On-site
Top industryHealthcare

Showing 5 of 136+ Clinical Research Nurse jobs

Boston Children's Hospital
Clinical Research Coordinator
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Boston Children's Hospital
New 7h ago
Clinical Research Coordinator
Boston Children's Hospital
Boston, Massachusetts
Administrative & Office Support
Office Management
Project Management
$52k.8 - $84k/yr
Hybrid
Master's degree
5,001-10,000

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Massachusetts General Hospital
Clinical Research Coordinator II
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Massachusetts General Hospital
New 8h ago
Clinical Research Coordinator II
Massachusetts General Hospital
Boston, Massachusetts
Business Development
Growth Marketing
Marketing
$24.28 - $39.43/hr
Bachelor's degree

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Beth Israel Lahey Health
Clinical Research Student
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Beth Israel Lahey Health
New 11h ago
Clinical Research Student
Beth Israel Lahey Health
Boston, Massachusetts
Biotech & Life Sciences
Environmental & Physical Sciences
Laboratory Research
Research & Academia
$15 - $24.04/hr

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Shriners Children's
Clinical Research Program Manager
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Shriners Children's
New 12h ago
Clinical Research Program Manager
Shriners Children's
Boston, Massachusetts
Corporate Training
Educational Administration
Program Management
Master's degree
5,001-10,000

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Moderna
Sr. Research Associate, Clinical Biomarker Laboratory, Flow Cytometry
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Moderna
Added 1d ago
Sr. Research Associate, Clinical Biomarker Laboratory, Flow Cytometry
Moderna
Norwood, Massachusetts
Data Analytics
Data Science
Research & Academia
$74k - $118k/yr
Bachelor of Science
1,001-5,000

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See All 136+ Clinical Research Nurse Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

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Clinical Research Nurse Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Cambridge
9 jobs
Burlington
7 jobs
Plymouth
4 jobs
Brookline
4 jobs
Worcester
3 jobs
Lowell
2 jobs
Watertown
2 jobs
Framingham
2 jobs

Clinical Research Nurse Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

  • Dana-Farber Cancer Institute
    Dana-Farber Cancer Institute19
  • Massachusetts General Hospital
    Massachusetts General Hospital18
  • Beth Israel Lahey Health
    Beth Israel Lahey Health16
  • Headlands Research
    Headlands Research8
  • Boston University
    Boston University6

Top Industries Hiring

  • Healthcare & Medical Services22
  • Biotechnology & Pharmaceuticals12
  • Staffing & Recruiting2
  • Education1
  • Consulting & Professional Services1

What Massachusetts Employers Look For

The qualifications that appear most often in clinical research nurse jobs across Massachusetts.

  • Active Massachusetts Registered Nurse license issued by the Massachusetts Board of Registration in Nursing
  • Minimum two years of clinical nursing experience in a hospital or patient-care setting
  • Experience with clinical trial protocols and Good Clinical Practice guidelines
  • Certified Clinical Research Professional or Certified Clinical Research Coordinator credential preferred
  • Proficiency with electronic data capture systems such as REDCap, Medidata, or similar platforms
  • Strong knowledge of FDA regulations and IRB submission and approval processes

Clinical Research Nurse Jobs in Massachusetts: Frequently Asked Questions

How do you become a clinical research nurse in Massachusetts?

You must hold an active Registered Nurse license issued by the Massachusetts Board of Registration in Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN exam. Most Massachusetts employers also expect at least two years of direct patient care experience before moving into research. Earning a credential such as the Certified Clinical Research Professional strengthens your application considerably and is often preferred by academic medical centers and pharmaceutical sponsors in the state.

Which companies hire clinical research nurses in Massachusetts?

Employers hiring clinical research nurses in Massachusetts right now include Dana-Farber Cancer Institute, Massachusetts General Hospital, and Beth Israel Lahey Health, based on current listings on Migrate Mate as of August 2026. Massachusetts's density of academic health systems, global pharmaceutical headquarters, and contract research organizations means consistent, year-round demand across the state.

Which Massachusetts cities have the most clinical research nurse jobs?

Boston, Cambridge, and Burlington have the most clinical research nurse openings in Massachusetts. Boston and Cambridge dominate because of their concentration of teaching hospitals, biotech campuses, and pharmaceutical sponsors, while Worcester draws steady demand from UMass Memorial Health and its affiliated research programs.

Are there remote clinical research nurse jobs in Massachusetts?

Yes, but they're rare. Clinical research nursing is primarily a hands-on, site-based role requiring direct patient contact, protocol assessments, and on-site monitoring. About 50% of clinical research nurse openings tied to Massachusetts are remote or hybrid as of August 2026, and those positions typically cover data review, regulatory document management, or remote patient monitoring within decentralized trial designs.

How can I get hired as a clinical research nurse in Massachusetts with little or no experience?

The most realistic entry path is applying for a clinical research coordinator or research associate nurse role at one of Massachusetts's large academic health systems, which regularly post positions open to nurses with bedside experience but no prior trial background. Mass General Brigham, Boston Medical Center, and Dana-Farber Cancer Institute all run structured onboarding and training programs for research staff new to clinical trials. Completing a Good Clinical Practice certification course and volunteering with an IRB committee or quality-improvement project adds concrete credibility to applications.

Where can I find and apply to clinical research nurse jobs in Massachusetts?

You can find and apply to clinical research nurse jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings. Find roles that fit your experience and location and apply directly to the employer through each listing.

See All 136+ Clinical Research Nurse Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Clinical Research Nurse Jobs