Clinical Research Nurse Jobs in Ohio
Clinical Research Nurse jobs in Ohio are consistently in demand, concentrated in academic medical centers, hospital-based research programs, and pharmaceutical and device trial sites, with openings at every level from newly licensed nurses entering clinical research through senior coordinators and principal investigators. Columbus, Cleveland, and Cincinnati anchor the market, with major employers such as The Ohio State University Wexner Medical Center, Cleveland Clinic, and Cincinnati Children's Hospital Medical Center maintaining ongoing clinical trial programs. Oncology trials, cardiovascular research, and pediatric studies represent the most active specialties for Ohio-based clinical research nurses. Find a role that fits below and apply directly.
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Location: METROHEALTH MEDICAL CENTER
Biweekly Hours: 80.00
Shift: 8-4:30
The MetroHealth System is redefining health care by going beyond medical treatment to improve the foundations of community health and well-being: affordable housing, a cleaner environment, economic opportunity and access to fresh food, convenient transportation, legal help and other services. The system strives to become as good at preventing disease as it is at treating it. Founded in 1837, Cuyahoga County’s safety-net health system operates four hospitals, four emergency departments and more than 20 health centers.
Summary:
Plans for, delivers, documents, and observes the progress of subjects enrolled in research studies in accordance with study protocols. Assists and collaborates with Research department leadership in the development of study budgets that are representative of the procedures outlined within protocols. Upholds the mission, vision, values, and customer service standards of The MetroHealth System.
Qualifications:
Required: Associate Degree in a Science, Healthcare, or other related field. Three years of experience working as a clinical research coordinator working with human subjects, or two years of experience and one of the following certifications: • Certified Clinical Research Coordinator (CCRC) by the Association of Clinical Research Professionals (ACRP) • Certified Clinical Research Professional by the Society of Clinical Research Associates (SOCRA). • Advanced Clinical Research Coordinator Certification (ACRCC) by the Certified Clinical Research Professional Society (CCRPS). In lieu of degree, five years of experience as a clinical research coordinator working with human subjects. Current Basic Life Support (BLS) certification from the American Heart Association (AHA) or obtains within 90 days of hire. Experience working with an Institutional Review Board (IRB). Good organizational and problem-solving skills. Proficiency in personal computers and various software/database applications (i.e. EPIC, OnBase, and the Microsoft Office Suite). Excellent interpersonal, written, and verbal communication skills. Maintains competencies in clinical areas. Willing and able to adhere to flex work schedules as needed, including weekend hours. Ability to interact effectively with a wide range of cultural, ethnic, racial, and socioeconomic backgrounds. Preferred: Bachelor’s Degree in Science or another related field. Experience with finance/billing. Currently a Certified Clinical Research Coordinator (CCRC) by the Association of Clinical Research Professionals (ACRP) or the Society of Clinical Research Associates (SOCRA). Physical Requirements: May sit, stand, stoop, bend, and ambulate intermittently during the day. May need to sit or stand for extended periods. See in the normal visual range with or without correction. Hear in the normal audio range with or without correction. Finger dexterity to operate office equipment required. May need to lift up to twenty-five (25) pounds on occasion. Ability to communicate in face-to-face, phone, email, and other communications. Ability to see computer monitor and departmental documents. Requires some exposure to communicable diseases or body fluids. Requires some exposure to chemicals and cleaning products.
See All 54 Clinical Research Nurse Jobs in Ohio
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Find Clinical Research Nurse JobsClinical Research Nurse Jobs by City in Ohio
Where Ohio roles are concentrated, by current openings.
Clinical Research Nurse Job Market in Ohio
A snapshot from current Ohio openings, updated as new roles post.
Who's Hiring
- The Ohio State University Wexner Medical Center10

- Nationwide Children's Hospital5

- The Ohio State University4

- Cincinnati Children's Hospital4

- Medpace3

Top Industries Hiring
- Healthcare & Medical Services
- Education
- Biotechnology & Pharmaceuticals
- Technology & Software
What Ohio Employers Look For
The qualifications that appear most often in clinical research nurse jobs across Ohio.
- Active registered nurse license issued or recognized by the Ohio Board of Nursing
- Bachelor of Science in Nursing (BSN) or higher degree in nursing or a health science
- Minimum one to two years of direct patient care or clinical nursing experience
- Certified Clinical Research Coordinator (CCRC) or CCRN credential preferred or required
- Experience with informed consent processes, protocol adherence, and GCP guidelines
- Proficiency with electronic data capture systems and clinical trial management software
Clinical Research Nurse Jobs in Ohio: Frequently Asked Questions
How do you become a clinical research nurse in Ohio?
You become a clinical research nurse in Ohio by first obtaining an active registered nurse license through the Ohio Board of Nursing, which requires passing the NCLEX-RN exam after completing an accredited nursing program. Most employers prefer a BSN at minimum. From there, gaining bedside experience in areas like oncology or cardiology builds the clinical foundation research sites look for, and earning a credential such as the CCRC or CCRN strengthens your application.
Which companies hire clinical research nurses in Ohio?
Employers hiring clinical research nurses in Ohio right now include The Ohio State University Wexner Medical Center, Nationwide Children's Hospital, and The Ohio State University, based on current listings on Migrate Mate as of August 2026. Ohio's concentration of academic medical centers, nonprofit hospital systems, and pharmaceutical contract research organizations means hiring activity is spread across institutional, industry-sponsored, and independent trial site settings.
Which Ohio cities have the most clinical research nurse jobs?
Columbus, Cincinnati, and Cleveland account for the largest share of clinical research nurse openings in Ohio as of August 2026. Columbus leads because of The Ohio State University Wexner Medical Center and a dense cluster of biotech and pharma trial sites, Cleveland draws from Cleveland Clinic's internationally recognized research enterprise, and Cincinnati benefits from Cincinnati Children's and UC Health running high-volume trial programs across multiple therapeutic areas.
Are there remote clinical research nurse jobs in Ohio?
Yes, but they're rare. Clinical research nursing is inherently hands-on, requiring patient contact, specimen handling, and on-site protocol execution, so fully remote roles make up a small share of openings. About 6% of clinical research nurse openings tied to Ohio are remote or hybrid as of August 2026, and those positions tend to cover data abstraction, regulatory documentation, or remote patient monitoring rather than active trial coordination.
How can I get hired as a clinical research nurse in Ohio with little or no experience?
The most realistic entry path is applying for a clinical research coordinator or research associate role at a large Ohio academic medical center that accepts nurses transitioning from bedside care. The Ohio State University Wexner Medical Center and Cleveland Clinic both run structured onboarding programs that bring in nurses from med-surg, oncology, or ICU units and train them in Good Clinical Practice and protocol management. Completing a GCP certification course before applying and framing any quality improvement or documentation experience as research-adjacent gives candidates without prior trial experience a meaningful edge.
Where can I find and apply to clinical research nurse jobs in Ohio?
You can find and apply to clinical research nurse jobs in Ohio on Migrate Mate, which lists current Ohio openings from employers actively hiring right now. Find roles that fit your experience level and specialty area, then apply directly to the employers posting them.
See All 54 Clinical Research Nurse Jobs in Ohio
Find roles in Ohio that match your experience and apply in just a few clicks.
Find Clinical Research Nurse Jobs