Clinical Informatics Manager Jobs

Clinical Informatics Manager jobs are open across health systems, hospitals, academic medical centers, and health IT vendors, from mid-level analyst leads to senior and director-level roles, with specializations in EHR implementation, clinical decision support, and population health informatics. See the openings below and apply to the ones that match your experience.

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Overview

Open roles175+
Top stateCalifornia
Top employerCVS Health
Top citySacramento, CA
Work type45% On-site
Top industryHealthcare

Showing 5 of 175+ Clinical Informatics Manager jobs

Clinical Innovation & Informatics, Health Informatics BI Analyst
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New 22h ago
Clinical Innovation & Informatics, Health Informatics BI Analyst
Siemens Healthineers
Remote
Business Analysis
Business Operations
Data Analytics
$113k - $156k/yr
Remote (US)
Bachelor's degree
10,000+

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Clinical Informatics Specialist
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New 22h ago
Clinical Informatics Specialist
Ascension
Milwaukee, Wisconsin
Biotech & Life Sciences
Clinical Trials
Healthcare Administration
$79k.88 - $146k.05/yr
Hybrid
High school diploma or GED
10,000+

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Pharmacist, Clinical Informatics
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Added 1d ago
Pharmacist, Clinical Informatics
Emplify Health
La Crosse, Wisconsin
Clinical Support
Healthcare Administration
Pharmacy
$125k - $188k/yr
Six Sigma Certification
5,001-10,000

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IT Clinical Informatics Pharmacist
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Added 1d ago
IT Clinical Informatics Pharmacist
Foundation Health Partners
Fairbanks, Alaska
Customer Success
Program Management
Project & Program Management
Project Management
$36.44 - $58.3/hr
Bachelor's degree
1,001-5,000

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Director Clinical Informatics and Practice Transformation-SWHR
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Added 1d ago
Director Clinical Informatics and Practice Transformation-SWHR
Southwestern Health Resources
Dallas, Texas
Business Operations
Business Strategy
Consulting & Professional Services
Hybrid
Master's degree
501-1,000

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Clinical Informatics Manager Job Market

Who's Hiring

  • CVS Health10
  • Cone Health5
  • Medpace4
  • Sutter Health4
  • Ascension3

Top Industries Hiring

  • Healthcare & Medical Services19
  • Insurance9
  • Biotechnology & Pharmaceuticals3
  • Education2
  • Science & Research2

What Employers Look For

The qualifications that appear most often in clinical informatics manager jobs.

  • Bachelor's or master's degree in health informatics, nursing, clinical informatics, or a related field
  • Hands-on experience implementing or optimizing Epic, Cerner, or another major EHR platform
  • CPHIMS, PMP, or clinical licensure such as RN or RT preferred or required
  • Three or more years of experience in a clinical or health IT setting with project leadership responsibilities
  • Proficiency in clinical workflow analysis, process improvement, and stakeholder training
  • Familiarity with HL7, FHIR, interoperability standards, and clinical data governance practices

Tips for Your Clinical Informatics Manager Job Search

Tailor your resume to EHR platforms

Hiring managers scan for specific system names like Epic, Cerner, or Meditech. List every platform you've configured, trained on, or led a go-live for, and pair each with the clinical domain it touched, such as inpatient nursing workflows or ambulatory scheduling.

Highlight clinical and technical credentials together

Many applicants lead with either a clinical background or an IT background, but not both. If you hold an RN license alongside a PMP or CPHIMS certification, place both prominently in your summary so reviewers immediately see the clinical-operational bridge you bring.

Apply early to roles that fit

Migrate Mate lists clinical informatics manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Filter for health system versus vendor roles

Health system roles focus on internal workflow optimization and clinician adoption, while vendor roles center on client implementations and product support. Your resume framing and cover letter emphasis should shift depending on which environment you're targeting, so decide before you apply.

Prepare a change management story for interviews

Interviewers for this role almost always ask how you drove clinician adoption of a new system or workflow. Walk in with a specific example that names the stakeholder resistance you faced, the approach you used, and the measurable outcome, such as a reduction in documentation errors or time-to-order.

Negotiate scope alongside compensation

When you receive an offer, ask which departments fall under your direct authority and whether the role owns project budgets or only advises on them. Scope ambiguity is common in informatics titles, and clarifying it before you accept shapes your actual influence on the job.

Clinical Informatics Manager Jobs: Frequently Asked Questions

Which companies are hiring the most clinical informatics managers?

CVS Health, Cone Health, and Medpace are hiring the most clinical informatics managers right now, with openings concentrated in California, North Carolina, and Texas, based on current listings on Migrate Mate as of November 2026. Large integrated health systems and academic medical centers account for the majority of active postings.

How many clinical informatics manager jobs are remote?

About 55% of clinical informatics manager openings are fully remote or hybrid as of November 2026, with remote availability highest in vendor-side implementation consulting and population health analytics roles. Health system positions tied to on-site clinician training or command center oversight are more likely to require an in-person presence.

How do you become a clinical informatics manager?

Start with a clinical or health IT background, then pursue formal education in informatics through a graduate certificate or master's program. Gain hands-on EHR project experience as an analyst or workflow specialist, then take on a lead or project manager role to build supervisory experience. Earning a certification like CPHIMS demonstrates cross-disciplinary competency and helps you stand out when applying for manager-level roles.

Can I get hired as a clinical informatics manager with little experience?

Moving directly into a manager title with no informatics experience is rare, but candidates with strong clinical backgrounds, such as registered nurses or respiratory therapists, often enter the field faster than those coming from pure IT. Employers value firsthand knowledge of clinical workflows, so positions like informatics analyst or EHR trainer serve as practical entry points that can lead to a manager role within a few years.

What does the clinical informatics manager interview process look like?

Most processes include an initial screening call with HR, followed by a technical or scenario-based interview with the informatics director or IT leadership, and a final panel interview that often includes clinical stakeholders such as nursing or physician leadership. Candidates are frequently asked to walk through a past implementation project, discuss how they handled clinician resistance, and sometimes complete a brief case study or workflow assessment before the final round.

Where can I find and apply to clinical informatics manager jobs?

You can find and apply to clinical informatics manager jobs on Migrate Mate, which lists current openings from across the United States. Search for roles that match your EHR background, clinical domain, or seniority level, and apply directly to each listing that fits your experience and location preferences.

See All 175+ Clinical Informatics Manager Jobs

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