Clinical Nurse Jobs in San Antonio, TX

Clinical Nurse jobs in San Antonio are in strong demand across the South Texas Medical Center, the Medical Center district, and Downtown, driven by the city's large hospital systems, military-affiliated medical facilities, and growing outpatient networks. Employers hiring right now include Methodist Healthcare System, UT Health Science Center at San Antonio, and University Health. Find a role that fits below and apply directly.

Find Clinical Nurse Jobs

Overview

Open roles224+
Top employerMethodist Healthcare System
Work type100% On-site
Top credentialAssociate's
Companies hiring11

Showing 5 of 224+ Clinical Nurse jobs

Clinical Care Transition Specialist / Registered Nurse
We won't show you this job again
New 23h ago
Clinical Care Transition Specialist / Registered Nurse
Option Care Health
San Antonio, Texas
Brand Marketing
Growth Marketing
Marketing
$85k.86 - $141k.27/yr
5,001-10,000

Have you applied for this role?

Clinical Nurse Coordinator Emergency Room RN
We won't show you this job again
Added 2d ago
Clinical Nurse Coordinator Emergency Room RN
Methodist Healthcare System
San Antonio, Texas
Community & Nonprofit Services
Customer Service
Event Planning
5,001-10,000

Have you applied for this role?

Clinical Nurse Coordinator PCICU
We won't show you this job again
Added 2d ago
Clinical Nurse Coordinator PCICU
Methodist Healthcare System
San Antonio, Texas
Business Development
Growth Marketing
Marketing
5,001-10,000

Have you applied for this role?

CTO Clinical Research Nurse-Associate (MaysCC CTO Admin)
We won't show you this job again
Added 4d ago
CTO Clinical Research Nurse-Associate (MaysCC CTO Admin)
UT Health Science Center at San Antonio
San Antonio, Texas
Business Operations
Project & Program Management
Project Management
CPR Certification
5,001-10,000

Have you applied for this role?

Clinical Nurse Coordinator Emergency Department RN
We won't show you this job again
Added 1w ago
Clinical Nurse Coordinator Emergency Department RN
Methodist Healthcare System
San Antonio, Texas
Customer Service
Healthcare Administration
Human Resources
5,001-10,000

Have you applied for this role?

See All 224+ Clinical Nurse Jobs in San Antonio

Find roles in San Antonio that match your experience and apply in just a few clicks.

Find Clinical Nurse Jobs

Clinical Nurse Job Market in San Antonio

Who's Hiring

  • Methodist Healthcare System136
  • UT Health Science Center at San Antonio24
  • University Health12
  • Methodist Hospital Landmark12
  • CHRISTUS Health6

Top Industries Hiring

  • Healthcare & Medical Services

Clinical Nurse Jobs in San Antonio: Frequently Asked Questions

How do I get a clinical nurse job in San Antonio?

The strongest hiring in San Antonio is concentrated in the South Texas Medical Center corridor, which hosts more than 40 medical institutions, and in military-affiliated facilities like Brooke Army Medical Center. Acute care, oncology, and perioperative nursing see consistent openings. Candidates with ACLS or specialty certifications and hands-on experience in high-volume units stand out in this market.

Which companies hire clinical nurses in San Antonio?

San Antonio clinical nurse roles are posted by Methodist Healthcare System, UT Health Science Center at San Antonio, and University Health and others right now, based on current listings on Migrate Mate as of November 2026. The city's employer mix includes large regional hospital systems, federally operated military medical centers, and an expanding base of ambulatory surgery and specialty clinic operators.

Are there remote clinical nurse jobs in San Antonio?

Yes, though remote work is limited for hands-on bedside roles and more common in utilization review, case management, and telehealth triage positions. About 0% of clinical nurse openings tied to San Antonio are remote or hybrid as of November 2026. Insurance-affiliated and managed care employers based in the city tend to post the most remote-eligible clinical roles.

How can I get a clinical nurse job in San Antonio with little or no experience?

The most realistic entry path in San Antonio is applying to new graduate residency programs run by the large hospital systems in the South Texas Medical Center, which are structured to bring ADN and BSN graduates into supervised acute care roles. Ambulatory clinics, community health centers serving the city's federally qualified health program network, and long-term care facilities also hire entry-level nurses regularly and offer a practical foundation for building clinical hours.

Which industries hire the most clinical nurses in San Antonio?

San Antonio clinical nurse roles concentrate in Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. The city's outsized military presence, one of the largest concentrations of active-duty and veteran healthcare in the country, combines with a dense private hospital corridor to make San Antonio one of the more active clinical nursing markets in Texas.

See All 224+ Clinical Nurse Jobs in San Antonio

Find roles in San Antonio that match your experience and apply in just a few clicks.

Find Clinical Nurse Jobs