Clinical Nurse Jobs in San Antonio, TX

Clinical Nurse jobs in San Antonio are in strong demand across the South Texas Medical Center, the Medical Center district, and Downtown, driven by the city's large hospital systems, military-affiliated medical facilities, and growing outpatient networks. Employers hiring right now include Methodist Healthcare System, Methodist Hospital Landmark, and UT Health Science Center at San Antonio. Find a role that fits below and apply directly.

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Overview

Open roles225+
Top employerMethodist Healthcare System
Work type100% On-site
Top credentialAssociate's
Companies hiring9

Showing 5 of 225+ Clinical Nurse jobs

Methodist Healthcare System
Clinical Nurse Coordinator RN ER Children Dept
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Methodist Healthcare System
Added 2d ago
Clinical Nurse Coordinator RN ER Children Dept
Methodist Healthcare System
San Antonio, Texas
Business Development
Customer Success
Partnerships & Business Development
Project Management
5,001-10,000

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Peterson Health
Registered Nurse, Clinical Decision Unit | Full Time | Night Shift
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Peterson Health
Added 3d ago
Registered Nurse, Clinical Decision Unit | Full Time | Night Shift
Peterson Health
San Antonio, Texas
Healthcare Administration
Nursing
Patient Services & Wellbeing
PALS Certification
1,001-5,000

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Peterson Health
Registered Nurse, Clinical Decision Unit | Full Time | Day Shift
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Peterson Health
Added 3d ago
Registered Nurse, Clinical Decision Unit | Full Time | Day Shift
Peterson Health
San Antonio, Texas
Healthcare Administration
Nursing
Patient Services & Wellbeing
PALS Certification
1,001-5,000

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Methodist Healthcare System
Clinical Nurse Coordinator RN - Medical Telemetry
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Methodist Healthcare System
Added 4d ago
Clinical Nurse Coordinator RN - Medical Telemetry
Methodist Healthcare System
San Antonio, Texas
Healthcare Administration
Human Resources
Nursing
5,001-10,000

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UT Health Science Center at San Antonio
Clinical Research Nurse-Intermediate (Neurosurgery)
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UT Health Science Center at San Antonio
Added 5d ago
Clinical Research Nurse-Intermediate (Neurosurgery)
UT Health Science Center at San Antonio
San Antonio, Texas
Biotech & Life Sciences
Clinical Trials
Healthcare Administration
5,001-10,000

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See All 225+ Clinical Nurse Jobs in San Antonio

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Clinical Nurse Job Market in San Antonio

Who's Hiring

  • Methodist Healthcare System
    Methodist Healthcare System131
  • M
    Methodist Hospital Landmark26
  • UT Health Science Center at San Antonio
    UT Health Science Center at San Antonio21
  • CHRISTUS Health
    CHRISTUS Health16
  • Peterson Health
    Peterson Health10

Top Industries Hiring

  • Healthcare & Medical Services

Clinical Nurse Jobs in San Antonio: Frequently Asked Questions

How do I get a clinical nurse job in San Antonio?

The strongest hiring in San Antonio is concentrated in the South Texas Medical Center corridor, which hosts more than 40 medical institutions, and in military-affiliated facilities like Brooke Army Medical Center. Acute care, oncology, and perioperative nursing see consistent openings. Candidates with ACLS or specialty certifications and hands-on experience in high-volume units stand out in this market.

Which companies hire clinical nurses in San Antonio?

San Antonio clinical nurse roles are posted by Methodist Healthcare System, Methodist Hospital Landmark, and UT Health Science Center at San Antonio and others right now, based on current listings on Migrate Mate as of September 2026. The city's employer mix includes large regional hospital systems, federally operated military medical centers, and an expanding base of ambulatory surgery and specialty clinic operators.

Are there remote clinical nurse jobs in San Antonio?

Yes, though remote work is limited for hands-on bedside roles and more common in utilization review, case management, and telehealth triage positions. About 0% of clinical nurse openings tied to San Antonio are remote or hybrid as of September 2026. Insurance-affiliated and managed care employers based in the city tend to post the most remote-eligible clinical roles.

How can I get a clinical nurse job in San Antonio with little or no experience?

The most realistic entry path in San Antonio is applying to new graduate residency programs run by the large hospital systems in the South Texas Medical Center, which are structured to bring ADN and BSN graduates into supervised acute care roles. Ambulatory clinics, community health centers serving the city's federally qualified health program network, and long-term care facilities also hire entry-level nurses regularly and offer a practical foundation for building clinical hours.

Which industries hire the most clinical nurses in San Antonio?

San Antonio clinical nurse roles concentrate in Healthcare & Medical Services, based on current listings on Migrate Mate as of September 2026. The city's outsized military presence, one of the largest concentrations of active-duty and veteran healthcare in the country, combines with a dense private hospital corridor to make San Antonio one of the more active clinical nursing markets in Texas.

See All 225+ Clinical Nurse Jobs in San Antonio

Find roles in San Antonio that match your experience and apply in just a few clicks.

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