Clinical Nurse Jobs in Houston, TX
Clinical Nurse jobs in Houston are concentrated in the Texas Medical Center, Midtown, and the Memorial area, with strong demand from health systems, specialty hospitals, and outpatient clinics across critical care, oncology, and perioperative care. Employers actively hiring right now include MD Anderson Cancer Center, HCA Houston Healthcare, and Texas Children's Hospital. Scan the live roles below and apply to whichever ones fit.
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Ideal candidate will have a Bachelor's Degree in Nursing, an RN license and at least twelve months of recent RN experience in Oncology and/or a Medical Surgical Inpatient setting.
Shift will be 7pm - 7am and 26 out of 52 weekend shifts per year.
MD Anderson offers our employees:
- Paid employee medical benefits (zero premium) starting on first day for employees who work 30 or more hours per week
- Group Dental, Vision, Life, AD&D and Disability coverage
- Paid time off (PTO) and Extended Illness Bank (EIB) paid leave accruals
- Paid institutional holidays, wellness leave, childcare leave, and other paid leave programs
- Tuition Assistance Program after six months of service
- Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans
- Employer paid life, AD&D and an illness-related reduced salary pay program
- Extensive wellness, recognition, fitness, employee health programs and employee resource groups
Essential Job Functions:
Function- Manages patient outcomes by providing, coordinating and supporting clinical aspects of direct patient care across the continuum of care.
Scope- Impacts quality of patient care, patient outcomes and use of resources in a designated area in collaboration with a multidisciplinary team.
Accountable for the management and provision of patient care in assigned area. Assesses patient's needs for nursing care and multidisciplinary team.
- Collaborates with physicians, other services, patient and patient's family to plan care and evaluate outcomes.
- Improves practice by integrating results and theories of research studies. Participates in data collection for current studies.
- Demonstrates clinical competency and compassion in providing care, using technology, administering medications, performing procedures and managing emergencies. Documents care according to established standards.
- Accesses, inputs and retrieves information from computer systems.
- Assures continuity of care through appropriate discharge planning, patient education and coordination of services. Acts as a patient and family advocate in order to uphold patient rights.
- Trains, coaches and assists team members to ensure optimum patient care and efficient use of resources.
Other duties assigned.
EDUCATION
- Required: Graduation from an accredited school of professional nursing.
- Preferred: Bachelor's Degree Nursing.
WORK EXPERIENCE
- Required: One year of Clinical RN experience.
- Preferred: At least two years of Clinical RN experience.
LICENSES AND CERTIFICATIONS
- Required: RN - Registered Nurse - State Licensure Current State of Texas Professional Nursing license. Upon Hire and
- Required: ACLS - Advanced Cardiac Life Support Upon Hire and
- Required: PALS - Pediatric Advanced Life Support If working in the following department: Nrsg Post Anesthesia Care Unit (600160). Upon Hire
- Preferred: OCN - Oncology Nurse Certification Upon Hire
- Preferred: Certification in specialty practice area. Upon Hire
OTHER REQUIREMENTS: All clinical nurses with less than one year of registered nurse (RN) work experience will be required to participate in the Clinical Nurse Residency Program.
The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.
This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state, or local laws unless such distinction is required by law.http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
Additional Information
- Requisition ID: 182257
- Employment Status: Full-Time
- Employee Status: Regular
- Work Week: Evening/Night
- Minimum Salary: US Dollar (USD) 68,000
- Midpoint Salary: US Dollar (USD) 105,200
- Maximum Salary : US Dollar (USD) 142,500
- FLSA: exempt and eligible for overtime, paid at a time and a half rate
- Fund Type: Hard
- Work Location: Onsite
- Pivotal Position: Yes
- Referral Bonus Available?: Yes
- Relocation Assistance Available?: Yes
#LI-Onsite
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Find Clinical Nurse JobsClinical Nurse Job Market in Houston
Who's Hiring
- MD Anderson Cancer Center58

- HCA Houston Healthcare35

- Texas Children's Hospital29

- Houston Methodist23

- Harris Health12

Top Industries Hiring
- Education
- Healthcare & Medical Services
Clinical Nurse Jobs in Houston: Frequently Asked Questions
How do I get a clinical nurse job in Houston?
Houston's Texas Medical Center is one of the largest medical complexes in the world, so targeting its member institutions gives you the widest pool of openings. Health systems, pediatric hospitals, and Level I trauma centers cluster there and in the Midtown and Memorial corridors. Candidates with ICU, oncology, or perioperative experience stand out in this market, and nurses who can demonstrate cross-unit flexibility get prioritized by Houston's high-volume employers.
Which companies hire clinical nurses in Houston?
Employers hiring clinical nurses in Houston right now include MD Anderson Cancer Center, HCA Houston Healthcare, and Texas Children's Hospital, based on current listings on Migrate Mate as of August 2026. Houston's hiring base includes large nonprofit health systems, specialty cancer and cardiac centers, and for-profit hospital networks, giving clinical nurses a range of practice environments to choose from.
Are there remote clinical nurse jobs in Houston?
Yes, though remote work is limited for hands-on clinical roles and more available for utilization review, case management, and telephonic triage positions. About 15% of clinical nurse openings tied to Houston are remote or hybrid as of August 2026, and those roles tend to sit within Houston's large managed care and insurance operations rather than its acute-care hospitals.
How can I get a clinical nurse job in Houston with little or no experience?
The most realistic entry path in Houston is a nurse residency or new-graduate program offered by the major health systems anchored in the Texas Medical Center. These structured programs rotate nurses through units and are designed specifically for candidates with limited floor experience. Community hospitals and long-term acute care facilities in the Greater Houston area also hire new graduates, and a willingness to start in med-surg or telemetry opens doors to specialty units within one to two years.
Which industries hire the most clinical nurses in Houston?
Houston clinical nurse roles concentrate in Education and Healthcare & Medical Services, based on current listings on Migrate Mate as of August 2026. Houston's position as home to the Texas Medical Center, combined with a fast-growing suburban population and a large energy-sector workforce requiring occupational health services, keeps demand broad and relatively consistent across both acute and ambulatory settings.
See All 193+ Clinical Nurse Jobs in Houston
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Find Clinical Nurse Jobs