COO Jobs in Boston, MA

COO jobs in Boston are concentrated in life sciences and biotech along the Seaport and Longwood Medical Area, financial services in the Financial District, and technology startups in Kendall Square-adjacent corridors, with steady demand across venture-backed and established firms. Employers actively hiring include Dana-Farber Cancer Institute, Whoop, and Vertex Pharmaceuticals. Scan the live roles below and apply to whichever ones fit.

Find COO Jobs in Boston

Overview

Open roles177+
Top employerDana-Farber Cancer Institute
Work type68% On-site
Top credentialBachelor's
Companies hiring100+

Showing 5 of 177+ COO jobs

CVS Health
Director, Strategy Operations
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CVS Health
Added 1d ago
Director, Strategy Operations
CVS Health
Boston, Massachusetts
On-Site
Bachelor's
10,000+

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CVS Health
Lead Director, Service Operations
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CVS Health
Added 2d ago
Lead Director, Service Operations
CVS Health
Boston, Massachusetts
On-Site
Bachelor's
10,000+

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HarbourVest
Director, Enterprise Operations & Strategy
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HarbourVest
Added 2d ago
Director, Enterprise Operations & Strategy
HarbourVest
Boston, Massachusetts
Business Operations
Project & Program Management
Strategy & Corporate Development
Compliance & Legal
Project Management
Business Strategy
Compliance & Risk
$165k - $180k/yr
Hybrid
Bachelor's
501-1,000

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Simmons University
Director or Associate Director of Operations
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Simmons University
Added 3d ago
Director or Associate Director of Operations
Simmons University
Boston, Massachusetts
Project & Program Management
Business Operations
Human Resources
Compliance & Legal
$60k - $95k/yr
Hybrid
Bachelor's
501-1,000

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Takeda Pharmaceuticals
Associate Director, Clinical Operations Program Lead
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Takeda Pharmaceuticals
Added 3d ago
Associate Director, Clinical Operations Program Lead
Takeda Pharmaceuticals
Boston, Massachusetts
Clinical Trials & Medical Research
Healthcare Administration
Project & Program Management
Clinical Trials
Project Management
$154k - $243k/yr
Remote (US)
Bachelor's
10,000+

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See All 177+ COO Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find COO Jobs in Boston

COO Job Market in Boston

Who's Hiring

  • Dana-Farber Cancer Institute
    Dana-Farber Cancer Institute11
  • Whoop
    Whoop6
  • Vertex Pharmaceuticals
    Vertex Pharmaceuticals6
  • Takeda Pharmaceuticals
    Takeda Pharmaceuticals5
  • CVS Health
    CVS Health4

Top Industries Hiring

  • Consulting & Professional Services18
  • Science & Research16
  • Technology & Software16
  • Healthcare & Medical Services15
  • Education14

COO Jobs in Boston: Frequently Asked Questions

How do I get a coo job in Boston?

Boston coo roles cluster in life sciences, fintech, and enterprise technology, so candidates with operational leadership experience in those sectors have the clearest path in. Companies concentrated in the Seaport, Longwood Medical Area, and Back Bay hire most actively. A record of scaling teams, managing P&L, and partnering with a CEO carries more weight here than credentials alone, particularly in the city's dense startup and growth-stage company ecosystem.

Which companies hire coos in Boston?

Employers hiring coos in Boston right now include Dana-Farber Cancer Institute, Whoop, and Vertex Pharmaceuticals, based on current listings on Migrate Mate as of June 2026. Boston's hiring base is a mix of large healthcare and financial institutions, venture-backed biotech firms, and maturing technology companies, all of which regularly seek experienced operational leaders.

Are there remote coo jobs in Boston?

Yes, though coo roles are less remote-friendly than most, since the position typically requires close coordination with leadership, staff, and physical operations. About 32% of coo openings tied to Boston are remote or hybrid as of June 2026, skewing toward hybrid arrangements rather than fully remote. Strategy, reporting, and investor relations duties are the functions most commonly handled off-site in Boston-based coo roles.

How can I get a coo job in Boston with little or no experience?

The most realistic entry path is moving into a director of operations or VP of operations role at a Boston-area growth-stage startup, where the step up to coo happens faster than at larger firms. Seaport and Cambridge-based technology and biotech startups regularly promote from within as they scale. Building familiarity with metrics-driven operations and cross-functional project leadership while in a senior director role positions you well for the transition locally.

Which industries hire the most coos in Boston?

Boston coo roles concentrate in Consulting & Professional Services, Science & Research, and Technology & Software, based on current listings on Migrate Mate as of June 2026. Boston's density of research hospitals, asset managers, and venture-funded technology companies makes those sectors the primary drivers of executive operational hiring in the city.

See All 177+ COO Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find COO Jobs in Boston