COO Jobs in Boston, MA

COO jobs in Boston are concentrated in life sciences and biotech along the Seaport and Longwood Medical Area, financial services in the Financial District, and technology startups in Kendall Square-adjacent corridors, with steady demand across venture-backed and established firms. Employers actively hiring include Vertex Pharmaceuticals, Boston University, and Takeda Pharmaceuticals. Scan the live roles below and apply to whichever ones fit.

Find COO Jobs in Boston

Overview

Open roles202+
Top employerVertex Pharmaceuticals
Work type62% Hybrid
Top credentialBachelor's degree
Companies hiring59

Showing 5 of 202+ COO jobs

Director of Pricing Operations
We won't show you this job again
New 8h ago
Director of Pricing Operations
Wood Mackenzie
Boston, Massachusetts
Project & Program Management
Business Operations
Compliance & Legal
Human Resources
Project Management
Revenue Operations & Enablement
Compliance & Risk
Hybrid
None
1,001-5,000

Have you applied for this role?

Operations Support Director I
We won't show you this job again
New 20h ago
Operations Support Director I
Flik Independent School Dining
Boston, Massachusetts
Business Operations
Bachelor's degree in business

Have you applied for this role?

Director of Operations and Sales
We won't show you this job again
New 22h ago
Director of Operations and Sales
Cornerstone Caregiving
Boston, Massachusetts
Business Operations
Executive Leadership & C-Suite
Project & Program Management
Project Management
Master's degree in business administration
51-200

Have you applied for this role?

Sr. Director, Club Operations - Boston
We won't show you this job again
New 22h ago
Sr. Director, Club Operations - Boston
Equinox
Boston, Massachusetts
Business Development
Community & Nonprofit Services
Customer Success
$150k - $160k/yr
10,000+

Have you applied for this role?

Operations Director (Law, Business & the US-EU Economy)
We won't show you this job again
Added 1d ago
Operations Director (Law, Business & the US-EU Economy)
The Mentor Group
Boston, Massachusetts
Business Operations
Program Management
Project Management
$90k - $100k/yr
Hybrid
Bachelor's degree

Have you applied for this role?

See All 202+ COO Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find COO Jobs in Boston

COO Job Market in Boston

Who's Hiring

  • Vertex Pharmaceuticals14
  • Boston University9
  • Takeda Pharmaceuticals9
  • Northeastern University9
  • State Street6

Top Industries Hiring

  • Education

COO Jobs in Boston: Frequently Asked Questions

How do I get a coo job in Boston?

Boston coo roles cluster in life sciences, fintech, and enterprise technology, so candidates with operational leadership experience in those sectors have the clearest path in. Companies concentrated in the Seaport, Longwood Medical Area, and Back Bay hire most actively. A record of scaling teams, managing P&L, and partnering with a CEO carries more weight here than credentials alone, particularly in the city's dense startup and growth-stage company ecosystem.

Which companies hire coos in Boston?

Employers hiring coos in Boston right now include Vertex Pharmaceuticals, Boston University, and Takeda Pharmaceuticals, based on current listings on Migrate Mate as of November 2026. Boston's hiring base is a mix of large healthcare and financial institutions, venture-backed biotech firms, and maturing technology companies, all of which regularly seek experienced operational leaders.

Are there remote coo jobs in Boston?

Yes, though coo roles are less remote-friendly than most, since the position typically requires close coordination with leadership, staff, and physical operations. About 83% of coo openings tied to Boston are remote or hybrid as of November 2026, skewing toward hybrid arrangements rather than fully remote. Strategy, reporting, and investor relations duties are the functions most commonly handled off-site in Boston-based coo roles.

How can I get a coo job in Boston with little or no experience?

The most realistic entry path is moving into a director of operations or VP of operations role at a Boston-area growth-stage startup, where the step up to coo happens faster than at larger firms. Seaport and Cambridge-based technology and biotech startups regularly promote from within as they scale. Building familiarity with metrics-driven operations and cross-functional project leadership while in a senior director role positions you well for the transition locally.

Which industries hire the most coos in Boston?

Boston coo roles concentrate in Education, based on current listings on Migrate Mate as of November 2026. Boston's density of research hospitals, asset managers, and venture-funded technology companies makes those sectors the primary drivers of executive operational hiring in the city.

See All 202+ COO Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find COO Jobs in Boston