COO Jobs in Boston, MA

COO jobs in Boston are concentrated in life sciences and biotech along the Seaport and Longwood Medical Area, financial services in the Financial District, and technology startups in Kendall Square-adjacent corridors, with steady demand across venture-backed and established firms. Employers actively hiring include Takeda Pharmaceuticals, Vertex Pharmaceuticals, and Northeastern University. Scan the live roles below and apply to whichever ones fit.

Find COO Jobs in Boston

Overview

Open roles181+
Top employerTakeda Pharmaceuticals
Work type61% Hybrid
Top credentialBachelor's degree
Companies hiring54

Showing 5 of 181+ COO jobs

City of Boston
Deputy Director of Operations
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City of Boston
Added 3d ago
Deputy Director of Operations
City of Boston
Boston, Massachusetts
Business Development
Executive Leadership & C-Suite
Partnerships & Business Development
$91k.15 - $129k.83/yr
Master's degree in public administration
1,001-5,000

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Massachusetts Eye and Ear
Director of Operations
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Massachusetts Eye and Ear
Added 3d ago
Director of Operations
Massachusetts Eye and Ear
Boston, Massachusetts
Business Analysis
Data Analytics
IT Support
Systems Administration
$124k.4 - $181k.59/yr
Bachelor's degree in business
1,001-5,000

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Takeda Pharmaceuticals
Director Clinical Operations
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Takeda Pharmaceuticals
Added 3d ago
Director Clinical Operations
Takeda Pharmaceuticals
Boston, Massachusetts
Business Strategy
Executive Leadership & C-Suite
Strategy & Corporate Development
$177k - $278k/yr
Remote (US)
Bachelor's degree
10,000+

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State Street
COO - Global Head of Business Operations, MD - State Street Investment Management
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State Street
Added 3d ago
COO - Global Head of Business Operations, MD - State Street Investment Management
State Street
Boston, Massachusetts
Customer Service
Customer Support
Hospitality & Guest Services
$170k - $268k/yr
Master's degree in business administration
10,000+

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City of Boston
Operations Deputy Director
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City of Boston
Added 4d ago
Operations Deputy Director
City of Boston
Boston, Massachusetts
Business Operations
Executive Leadership & C-Suite
Project & Program Management
Project Management
$100k.03 - $139k.11/yr
Bachelor's degree in business
1,001-5,000

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See All 181+ COO Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find COO Jobs in Boston

COO Job Market in Boston

Who's Hiring

  • Takeda Pharmaceuticals
    Takeda Pharmaceuticals11
  • Vertex Pharmaceuticals
    Vertex Pharmaceuticals11
  • Northeastern University
    Northeastern University8
  • Whoop
    Whoop5
  • State Street
    State Street5

Top Industries Hiring

  • Education
  • Science & Research
  • Consulting & Professional Services
  • Technology & Software
  • Construction & Real Estate

COO Jobs in Boston: Frequently Asked Questions

How do I get a coo job in Boston?

Boston coo roles cluster in life sciences, fintech, and enterprise technology, so candidates with operational leadership experience in those sectors have the clearest path in. Companies concentrated in the Seaport, Longwood Medical Area, and Back Bay hire most actively. A record of scaling teams, managing P&L, and partnering with a CEO carries more weight here than credentials alone, particularly in the city's dense startup and growth-stage company ecosystem.

Which companies hire coos in Boston?

Employers hiring coos in Boston right now include Takeda Pharmaceuticals, Vertex Pharmaceuticals, and Northeastern University, based on current listings on Migrate Mate as of September 2026. Boston's hiring base is a mix of large healthcare and financial institutions, venture-backed biotech firms, and maturing technology companies, all of which regularly seek experienced operational leaders.

Are there remote coo jobs in Boston?

Yes, though coo roles are less remote-friendly than most, since the position typically requires close coordination with leadership, staff, and physical operations. About 82% of coo openings tied to Boston are remote or hybrid as of September 2026, skewing toward hybrid arrangements rather than fully remote. Strategy, reporting, and investor relations duties are the functions most commonly handled off-site in Boston-based coo roles.

How can I get a coo job in Boston with little or no experience?

The most realistic entry path is moving into a director of operations or VP of operations role at a Boston-area growth-stage startup, where the step up to coo happens faster than at larger firms. Seaport and Cambridge-based technology and biotech startups regularly promote from within as they scale. Building familiarity with metrics-driven operations and cross-functional project leadership while in a senior director role positions you well for the transition locally.

Which industries hire the most coos in Boston?

Boston coo roles concentrate in Education, Science & Research, and Consulting & Professional Services, based on current listings on Migrate Mate as of September 2026. Boston's density of research hospitals, asset managers, and venture-funded technology companies makes those sectors the primary drivers of executive operational hiring in the city.

See All 181+ COO Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find COO Jobs in Boston