COO Jobs
COO jobs are open across technology, healthcare, financial services, manufacturing, and consumer brands, from growth-stage startups to large enterprises, with specializations in operations strategy, supply chain, and P&L management. Find a role that fits from the openings below and apply directly.
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INTRODUCTION
Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. Tempus is seeking a Director, Strategy & Operations to drive product ideation, strategy, and execution for novel multimodal AI products custom developed with Life Sciences partners.
ROLE AND RESPONSIBILITIES
This role will be responsible for managing the entire product lifecycle, from developing product concepts, based on scientific hypotheses and customer needs, through development, launch, commercialization, translating and ensuring alignment with partners’ business strategies and objectives. The Director, Strategy & Operations will take a highly collaborative approach with key stakeholders from Life Sciences companies to ideate new products, and define associated roadmaps. This role will work cross-functionally both internally and externally, across diverse science, engineering, medical, quality, regulatory, and commercial teams. In addition to AI product acumen, this role requires a strong understanding of the drug development lifecycle and the application of translational medicine throughout the stages of development and commercialization of therapeutics.
Key Responsibilities
- Understand Life Sciences partners’ business needs and scientific hypotheses, and translate these aims into product concepts, refined through iteration with partners.
- Translate early stage product ideas and proof-of-concept results into well-defined product profiles and clear roadmaps, considering partner needs.
- Drive clear communication and alignment with partners for all product-related workstreams.
- Manage the product lifecycle for Life Sciences custom products from inception and proof-of-concept through product development, launch, go-to-market, and post-market evaluation.
- Collaborate with internal medical, AI, and translational research subject matter experts to determine feasibility, technical approach, and drive execution.
- Optimize internal processes to improve product lifecycle delivery and time-to-market.
- Collaborate with quality and regulatory subject matter experts to ensure ongoing compliance with Paige and Tempus’s regulatory obligations and quality standards.
BASIC QUALIFICATIONS
- 5+ years of experience in product management or strategy at the intersection of healthcare and technology, including responsibility for the vision, strategy, and roadmap of complex products in regulated environments.
- Proven track record (2+ years) of managing AI products through the entire lifecycle, from ideation to launch (0 to 1).
- Extensive experience in customer and/or partner management.
- Excellent communication skills with a demonstrated ability to partner cross-functionally and engage diverse stakeholders across all organizational levels.
- Deep familiarity and demonstrated understanding of the drug development lifecycle.
- Familiarity with molecular biology, translational medicine, and diagnostics preferred.
- Experience working with Life Sciences or Biopharma partners in a product management or translational research role preferred.
- Skilled at engaging users, customers, and partners to distill feedback into clear, agile product requirements and roadmaps.
COMPENSATION
- NYC Base Salary Range: $150,000-$220,000
The expected salary range above is applicable if the role is performed from New York and may vary for other locations (California, Colorado, Illinois). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
INTRODUCTION
Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. Tempus is seeking a Director, Strategy & Operations to drive product ideation, strategy, and execution for novel multimodal AI products custom developed with Life Sciences partners.
ROLE AND RESPONSIBILITIES
This role will be responsible for managing the entire product lifecycle, from developing product concepts, based on scientific hypotheses and customer needs, through development, launch, commercialization, translating and ensuring alignment with partners’ business strategies and objectives. The Director, Strategy & Operations will take a highly collaborative approach with key stakeholders from Life Sciences companies to ideate new products, and define associated roadmaps. This role will work cross-functionally both internally and externally, across diverse science, engineering, medical, quality, regulatory, and commercial teams. In addition to AI product acumen, this role requires a strong understanding of the drug development lifecycle and the application of translational medicine throughout the stages of development and commercialization of therapeutics.
Key Responsibilities
- Understand Life Sciences partners’ business needs and scientific hypotheses, and translate these aims into product concepts, refined through iteration with partners.
- Translate early stage product ideas and proof-of-concept results into well-defined product profiles and clear roadmaps, considering partner needs.
- Drive clear communication and alignment with partners for all product-related workstreams.
- Manage the product lifecycle for Life Sciences custom products from inception and proof-of-concept through product development, launch, go-to-market, and post-market evaluation.
- Collaborate with internal medical, AI, and translational research subject matter experts to determine feasibility, technical approach, and drive execution.
- Optimize internal processes to improve product lifecycle delivery and time-to-market.
- Collaborate with quality and regulatory subject matter experts to ensure ongoing compliance with Paige and Tempus’s regulatory obligations and quality standards.
BASIC QUALIFICATIONS
- 5+ years of experience in product management or strategy at the intersection of healthcare and technology, including responsibility for the vision, strategy, and roadmap of complex products in regulated environments.
- Proven track record (2+ years) of managing AI products through the entire lifecycle, from ideation to launch (0 to 1).
- Extensive experience in customer and/or partner management.
- Excellent communication skills with a demonstrated ability to partner cross-functionally and engage diverse stakeholders across all organizational levels.
- Deep familiarity and demonstrated understanding of the drug development lifecycle.
- Familiarity with molecular biology, translational medicine, and diagnostics preferred.
- Experience working with Life Sciences or Biopharma partners in a product management or translational research role preferred.
- Skilled at engaging users, customers, and partners to distill feedback into clear, agile product requirements and roadmaps.
COMPENSATION
- NYC Base Salary Range: $150,000-$220,000
The expected salary range above is applicable if the role is performed from New York and may vary for other locations (California, Colorado, Illinois). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
COO Jobs by Experience Level
Top Cities Hiring COOs
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Find COO JobsCOO Job Market
Who's Hiring
- Cornerstone Caregiving58
- Thermo Fisher Scientific51
- IDEA Public Schools31
- Chick-fil-A Restaurants23C
- Merck19
Top Industries Hiring
- Education51
- Healthcare & Medical Services43
- Technology & Software23
- Biotechnology & Pharmaceuticals23
- Consulting & Professional Services16
What Employers Look For
The qualifications that appear most often in COO jobs.
- 10 or more years of progressive operational leadership experience
- Demonstrated P&L ownership across a full business unit or company
- Experience scaling teams and building cross-functional processes
- Strong financial acumen including budgeting, forecasting, and reporting
- Proven ability to translate strategy into executable operational plans
- Bachelor's degree required, MBA or equivalent advanced degree preferred
Tips for Your COO Job Search
Quantify operational outcomes on your resume
COO resumes live or die by metrics. Replace vague leadership claims with concrete results: headcount scaled, cost reduced as a percentage, revenue influenced, or cycle time cut. Hiring boards at this level screen for operators who can show what changed under their watch.
Tailor your story to stage of company
A seed-stage startup COO and a Fortune 500 COO are nearly different jobs. Lead your positioning with the stage you've operated in most recently, then tie every example to the specific challenges that stage demands, whether that's building process from scratch or optimizing at scale.
Apply early to roles that fit
Migrate Mate lists coo openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare a cross-functional leadership narrative
COO interviews probe how you align sales, product, finance, and operations toward a single goal. Before each interview, map out one specific initiative where you coordinated at least three functions. Practice narrating the tradeoffs, the resistance you faced, and how you resolved it.
Negotiate beyond base salary from day one
COO offers typically include equity, performance bonuses, and scope definitions that matter as much as cash. Know what percentage of the company you're being offered, what the vesting cliff looks like, and whether the operational scope is clearly defined before you respond to any term sheet.
Follow up with a written post-interview memo
After a final-round interview, send a brief memo, not just a thank-you note, that outlines your 90-day operating thesis for the role. This mirrors how effective COOs actually work and signals strategic readiness in a way that generic follow-ups never do.
COO Jobs: Frequently Asked Questions
Which companies are hiring the most COOs?
The companies hiring the most coos right now include Cornerstone Caregiving, Thermo Fisher Scientific, and IDEA Public Schools, with the largest share of openings in Texas, California, and New York, based on current listings on Migrate Mate as of August 2026. Demand is especially concentrated in high-growth technology companies and private-equity-backed businesses undergoing operational transformation.
How many COO jobs are remote?
About 53% of coo openings are fully remote or hybrid as of August 2026, though fully remote arrangements are less common at this level than in individual-contributor roles. Sub-areas like digital operations, SaaS company leadership, and tech-forward startups tend to offer the most location flexibility for coo candidates.
How do you become a COO?
Most coos build toward the role by first running a major function, such as finance, product, or supply chain, then taking on cross-functional responsibility, and eventually owning full P&L accountability. Gaining experience in high-stakes initiatives, building a reputation for execution under pressure, and developing direct relationships with board-level stakeholders accelerates the path considerably.
Can you get hired as a COO without prior C-suite experience?
Yes, particularly at startups and early-growth companies that prioritize operational results over formal titles. Candidates who've served as VP of Operations, General Manager, or Head of a major business unit with clear ownership over outcomes can make a credible case. Framing your resume around decisions made, teams built, and measurable results delivered matters more than the title you held.
What does the COO interview process look like?
COO interviews typically run across multiple rounds and include an initial conversation with the CEO or a board member, a deep operational case study or business diagnostic exercise, and a series of cross-functional interviews with the heads of finance, product, and sales. Final rounds often include a presentation of your operating philosophy or a 90-day plan for the specific business.
Where can I find and apply to COO jobs?
You can find and apply to coo jobs on Migrate Mate, which lists current openings from across the United States. Find roles that match your experience and the company stage you want to work in, then apply directly to each listing from the page.
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