COO Jobs in Irvine, CA

COO jobs in Irvine, California are in strong demand, with openings concentrated in the Irvine Business Complex, the Great Park neighborhoods, and the Spectrum Center corridor across technology, financial services, life sciences, and healthcare. Employers hiring right now include xe, AbbVie, and Weedmaps. Find a role that fits below and apply directly.

Find COO Jobs in Irvine

Overview

Open roles445+
Top employerxe
Work type50% Hybrid
Top credentialMaster's degree in business administration
Companies hiring17

Showing 5 of 445+ COO jobs

Planet DDS
Director, Revenue Operations
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Planet DDS
Added 1w ago
Director, Revenue Operations
Planet DDS
Irvine, California
Business Operations
Program Management
Project Management
$150k - $180k/yr
Bachelor's degree in finance

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Prudential Overall Supply
Cleanroom Operations Improvement Director
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Prudential Overall Supply
Added 1w ago
Cleanroom Operations Improvement Director
Prudential Overall Supply
Irvine, California
Business Development
Growth Marketing
Marketing
$140k - $180k/yr
Bachelor's degree
1,001-5,000

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AbbVie
Sr. Director, Global Assistant Controller & Finance Operations
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AbbVie
Added 1w ago
Sr. Director, Global Assistant Controller & Finance Operations
AbbVie
Irvine, California
Accounting
Audit
Bookkeeping & AP/AR
$207k - $393k/yr
Hybrid
Master's degree in accounting
10,000+

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Mission Healthcare
Hospice Director of Clinical Operations (RN)
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Mission Healthcare
Added 1w ago
Hospice Director of Clinical Operations (RN)
Mission Healthcare
Irvine, California
Business Development
Growth Marketing
Marketing
On-Site
Bachelor's degree
1,001-5,000

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Groupe SEB
Director of Service Operations
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Groupe SEB
Added 2w ago
Director of Service Operations
Groupe SEB
Irvine, California
Business Development
Growth Marketing
Marketing
$140k - $160k/yr
Hybrid
Bachelor's degree in business administration
10,000+

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See All 445+ COO Jobs in Irvine

Find roles in Irvine that match your experience and apply in just a few clicks.

Find COO Jobs in Irvine

COO Job Market in Irvine

Who's Hiring

  • X
    xe26
  • AbbVie
    AbbVie26
  • Weedmaps
    Weedmaps26
  • Directive
    Directive26
  • Groupe SEB
    Groupe SEB26

COO Jobs in Irvine: Frequently Asked Questions

How do I get a coo job in Irvine?

The strongest path into a coo role in Irvine is through the city's technology, financial services, and life sciences sectors, which drive the highest concentration of executive openings. Companies clustered in the Irvine Spectrum and Irvine Business Complex corridor actively promote from director and VP levels, so building operational depth in those industries locally puts you in the clearest line of sight for a coo opportunity.

Which companies hire coos in Irvine?

Companies currently hiring coos in Irvine include xe, AbbVie, and Weedmaps, per current listings on Migrate Mate as of September 2026. Irvine's employer base skews toward mid-market technology firms, regional financial institutions, and specialty healthcare organizations, all of which regularly seek senior operations leadership.

Are there remote coo jobs in Irvine?

Yes, though remote availability is limited for coo roles given the hands-on, cross-functional leadership the position requires. About 67% of coo openings tied to Irvine are remote or hybrid as of September 2026, with hybrid arrangements being far more common than fully remote. Strategic and administrative responsibilities tend to travel well remotely, while culture-building and on-site team oversight typically require an Irvine presence.

How can I get a coo job in Irvine with little or no experience?

The most realistic entry path is through an operations manager or director of operations role at one of Irvine's many growth-stage technology or healthcare companies, where smaller leadership teams mean faster advancement into the executive suite. Irvine's startup and mid-market ecosystem, particularly around the Irvine Spectrum, rewards candidates who demonstrate measurable process improvements and cross-department coordination early in their careers.

See All 445+ COO Jobs in Irvine

Find roles in Irvine that match your experience and apply in just a few clicks.

Find COO Jobs in Irvine