COO Jobs in San Antonio, TX

COO jobs in San Antonio are concentrated in the Medical Center, downtown, and the North Central corridor, with strong demand across healthcare, defense contracting, and financial services. Employers hiring right now include ATHRA SYSTEMS, Our Lady of the Lake University, and USAA. Find a role that fits below and apply directly.

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Overview

Open roles287+
Top employerATHRA SYSTEMS
Work type50% Remote
Top credentialBachelor's degree
Companies hiring16

Showing 5 of 287+ COO jobs

Director of Operations - Service & Installation
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Added 2d ago
Director of Operations - Service & Installation
Ace Mart Restaurant Supply
San Antonio, Texas
Business Development
Executive Leadership & C-Suite
Partnerships & Business Development
Bachelor's degree in business
201-500

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Director Operations
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Added 3d ago
Director Operations
Sonrava Health
San Antonio, Texas
Business Operations
Project & Program Management
Human Resources
Customer Service & Support
On-Site
Bachelor's

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Director of Enrollment CRM Operations - Our Lady of the Lake University
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Added 3d ago
Director of Enrollment CRM Operations - Our Lady of the Lake University
Our Lady of the Lake University
San Antonio, Texas
Content & Communications
Creative & Design
Marketing
Master's degree
501-1,000

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Director of Operations
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Added 1w ago
Director of Operations
Baird Foundation Repair
San Antonio, Texas
Business Strategy
Community & Nonprofit Services
Executive Leadership & C-Suite
$130k - $140k/yr
Bachelor's degree in business
51-200

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Divisional Director of Operations, SUD Services, Remote
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Added 1w ago
Divisional Director of Operations, SUD Services, Remote
ATHRA SYSTEMS
San Antonio, Texas
Business Development
Executive Leadership & C-Suite
Partnerships & Business Development
Remote (US)
Bachelor's degree in business administration

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See All 287+ COO Jobs in San Antonio

Find roles in San Antonio that match your experience and apply in just a few clicks.

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COO Job Market in San Antonio

Who's Hiring

  • ATHRA SYSTEMS32
  • Our Lady of the Lake University32
  • USAA16
  • DaVita16
  • Sevita16

Top Industries Hiring

  • Healthcare & Medical Services

COO Jobs in San Antonio: Frequently Asked Questions

How do I get a coo job in San Antonio?

Target San Antonio's highest-density hiring sectors: healthcare systems anchored around the South Texas Medical Center, defense and government contracting firms near Joint Base San Antonio, and financial services companies headquartered downtown. Candidates who can show P&L ownership and cross-functional leadership in those sectors move fastest. Networking through the San Antonio Chamber of Commerce and local industry groups also gives a meaningful edge over applicants applying cold.

Which companies hire coos in San Antonio?

Employers hiring coos in San Antonio right now include ATHRA SYSTEMS, Our Lady of the Lake University, and USAA, based on current listings on Migrate Mate as of November 2026. San Antonio's employer mix skews toward large health systems, military-adjacent contractors, and regional banks, alongside a growing set of tech-enabled companies establishing operations in the city.

Are there remote coo jobs in San Antonio?

Yes, though coo roles are less remote-friendly than individual contributor positions because the role typically requires direct oversight of people, facilities, and cross-functional coordination. About 67% of coo openings tied to San Antonio are remote or hybrid as of November 2026, with hybrid arrangements more common than fully remote. Strategic and advisory-focused coo roles at tech companies and consulting firms tend to offer the most location flexibility.

How can I get a coo job in San Antonio with little or no experience?

The most realistic path is moving into a director of operations or VP of operations role first, particularly at mid-size San Antonio employers in healthcare administration, logistics, or defense services, where internal promotion to coo is common. Local organizations like university health systems and regional insurers frequently post senior operations roles that serve as a direct pipeline. Building a record of measurable process improvements and team leadership in those environments is what converts an operations career into a coo candidacy.

Which industries hire the most coos in San Antonio?

The sectors hiring the most coos in San Antonio are Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. San Antonio's economy is shaped by its large military presence, one of the country's major medical districts, and an expanding cybersecurity and financial services base, which together drive consistent coo demand across those fields.

See All 287+ COO Jobs in San Antonio

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