CPT HR Director Jobs
HR Director roles on CPT let you lead compensation strategy, workforce planning, and organizational development as a direct extension of your graduate coursework. Your DSO must document how the position integrates with your degree program before you start, and part-time CPT must stay within 20 hours per week during the academic term.
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Get Access To All JobsAt Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.
Summary: We are seeking an accomplished and strategic Director of Laboratory Operations to lead and scale our NeXT Personal laboratory. In this high-visibility role, you will drive operational maturity, ensuring our high-complexity liquid biopsy laboratory functions at the gold-standard. Beyond overseeing daily operations, you will have the autonomy to shape the future of the lab, reporting directly to the VP of Operations with full accountability for departmental AOPs and OKRs. As a Director of Laboratory Operations, you will lead a multidisciplinary team of supervisors and associates to meet increasing demand, directly influencing patient outcomes in oncology. By joining us, you become a catalyst for growth, driving continuous improvement across our RUO, GLP, and CLIA/CAP operations. We are looking for a leader who thrives in a "Team Above Self" environment - someone who will act as a dedicated mentor to develop the next generation of laboratory leaders while ensuring that every sample processed reflects our unwavering commitment to patient care and diagnostic integrity.
Responsibilities: The Director of Laboratory Operations will be responsible for management and oversight of the RUO, GLP and CLIA/CAP laboratory operation and personnel.
- Accountability for overall laboratory operations and clinical test performance in accordance with federal and state regulations
- Oversee recruiting, training, and managing testing personnel, ensuring that all employees are adequately qualified and motivated to perform their duties
- Oversee validation, assay transfer, and verification of LDTs
- Prepare and attend Audits and Inspections (e.g. by pharma clients, CLIA / CAP, NYS, etc.)
- Lead a team of CLSs and Technical / General Supervisors
- Actively assist and lead, as needed, laboratory related NCs and CAPAs
- Attend and actively contribute to the monthly Personalis laboratories Quality Assurance meeting
- Identify and advocate cross functionally for scalable solutions that enhance quality and efficiency
- Develop strategic plan and AOP for their department
- Champion and lead OKR’s development, execution, and monitoring
- Architect capacity models to better understand our labor and equipment requirements
- Develop cost models to estimate cost and profit across product lines
- Drive an analytical approach to decision making and problem solving
- Act as a teacher, mentor, and advocate for personal growth with our young leaders and prepare them for achieving the next levels in their career
- Cultivate both short and long term logistical planning for patient sample processing
- Will own the TAT for the product line and endeavor to continually improve our delivery times
- Spearhead a high-performance culture rooted in harmony and a 'team-above-self' mindset. You will champion a solution-focused environment that prioritizes open communication, a sense of belonging, and a commitment to winning as a unified organization.
Education & Experience:
- Education: Bachelor’s Degree in a relevant scientific field (Advanced degree preferred).
- Licensure: Current and valid California Clinical Laboratory Scientist (CLS) License preferred. (Generalist or Limited Molecular Biology).
- Four (4) to six (6) plus years of experience as California CLS to qualify as Senior Technical Supervisor for the Personalis Molecular Pathology Clinical Laboratory required preferred
- Experience: Minimum 10+ years of extensive experience in high-complexity laboratory operations. Must have experience in high volume settings.
- Leadership: Minimum 5+ years of management experience with a proven ability to set vision, manage managers, and motivate teams for results.
- Technical Proficiency: Deep experience with NGS technologies, root cause analysis, logistics, capacity modeling, and LIMS.
The hiring range for this position is $210,000 to $245,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.
Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contact you.
Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.
Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.
Summary: We are seeking an accomplished and strategic Director of Laboratory Operations to lead and scale our NeXT Personal laboratory. In this high-visibility role, you will drive operational maturity, ensuring our high-complexity liquid biopsy laboratory functions at the gold-standard. Beyond overseeing daily operations, you will have the autonomy to shape the future of the lab, reporting directly to the VP of Operations with full accountability for departmental AOPs and OKRs. As a Director of Laboratory Operations, you will lead a multidisciplinary team of supervisors and associates to meet increasing demand, directly influencing patient outcomes in oncology. By joining us, you become a catalyst for growth, driving continuous improvement across our RUO, GLP, and CLIA/CAP operations. We are looking for a leader who thrives in a "Team Above Self" environment - someone who will act as a dedicated mentor to develop the next generation of laboratory leaders while ensuring that every sample processed reflects our unwavering commitment to patient care and diagnostic integrity.
Responsibilities: The Director of Laboratory Operations will be responsible for management and oversight of the RUO, GLP and CLIA/CAP laboratory operation and personnel.
- Accountability for overall laboratory operations and clinical test performance in accordance with federal and state regulations
- Oversee recruiting, training, and managing testing personnel, ensuring that all employees are adequately qualified and motivated to perform their duties
- Oversee validation, assay transfer, and verification of LDTs
- Prepare and attend Audits and Inspections (e.g. by pharma clients, CLIA / CAP, NYS, etc.)
- Lead a team of CLSs and Technical / General Supervisors
- Actively assist and lead, as needed, laboratory related NCs and CAPAs
- Attend and actively contribute to the monthly Personalis laboratories Quality Assurance meeting
- Identify and advocate cross functionally for scalable solutions that enhance quality and efficiency
- Develop strategic plan and AOP for their department
- Champion and lead OKR’s development, execution, and monitoring
- Architect capacity models to better understand our labor and equipment requirements
- Develop cost models to estimate cost and profit across product lines
- Drive an analytical approach to decision making and problem solving
- Act as a teacher, mentor, and advocate for personal growth with our young leaders and prepare them for achieving the next levels in their career
- Cultivate both short and long term logistical planning for patient sample processing
- Will own the TAT for the product line and endeavor to continually improve our delivery times
- Spearhead a high-performance culture rooted in harmony and a 'team-above-self' mindset. You will champion a solution-focused environment that prioritizes open communication, a sense of belonging, and a commitment to winning as a unified organization.
Education & Experience:
- Education: Bachelor’s Degree in a relevant scientific field (Advanced degree preferred).
- Licensure: Current and valid California Clinical Laboratory Scientist (CLS) License preferred. (Generalist or Limited Molecular Biology).
- Four (4) to six (6) plus years of experience as California CLS to qualify as Senior Technical Supervisor for the Personalis Molecular Pathology Clinical Laboratory required preferred
- Experience: Minimum 10+ years of extensive experience in high-complexity laboratory operations. Must have experience in high volume settings.
- Leadership: Minimum 5+ years of management experience with a proven ability to set vision, manage managers, and motivate teams for results.
- Technical Proficiency: Deep experience with NGS technologies, root cause analysis, logistics, capacity modeling, and LIMS.
The hiring range for this position is $210,000 to $245,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.
Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contact you.
Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.
Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)
See all CPT HR Director Jobs
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Get Access To All JobsHR Director CPT: Frequently Asked Questions
Does CPT work authorization cover strategic HR Director duties, or only entry-level HR tasks?
CPT authorization is tied to the scope your DSO approves, not the job title itself. If your program covers strategic workforce management, compensation design, and organizational development, your DSO can authorize a CPT position that includes those director-level responsibilities. The key is demonstrating in writing that the duties directly support your current curriculum, not that they match an entry-level profile.
Can I work as an HR Director on part-time CPT during the academic semester?
Yes. Part-time CPT is capped at 20 hours per week while classes are in session, and your DSO must authorize the specific position before your start date. HR Director roles with part-time hours are less common, but some employers structure them as consulting or project-based engagements that fit within the 20-hour limit. Confirm the arrangement in writing before your DSO files the CPT authorization.
How do I find HR Director roles where the employer already understands CPT authorization?
Search Migrate Mate for HR Director openings and filter by employers with established LCA or H-1B visa filing history. These companies have already navigated work authorization paperwork before, which means less time spent explaining CPT to a recruiter who has never encountered it. Prioritizing this subset of employers significantly shortens the offer timeline.
Does 12 months of full-time CPT affect my OPT eligibility after graduation?
Yes. If you accumulate 12 or more months of full-time CPT, you lose your OPT eligibility entirely. Part-time CPT, regardless of total duration, does not count toward that threshold. If you're planning to use OPT for H-1B transition after your HR Director CPT role ends, track your full-time CPT hours carefully and discuss the running total with your DSO before each authorization.
What documents does an employer need to provide to support my CPT authorization for an HR Director position?
Your employer typically needs to supply an offer letter that specifies job title, duties, start and end dates, hours per week, and work location. Your DSO may also request a brief description of how the role connects to your program of study. Some schools require a formal training agreement signed by both parties. Collect all of these before your authorization request, since missing documents are the most common reason DSO approval is delayed.