Cytogenetic Technologist Jobs
Cytogenetic Technologist jobs are open across hospital laboratories, academic medical centers, cancer research institutes, and reference labs, from entry-level to senior and supervisory roles, with specializations in clinical cytogenetics, oncology cytogenetics, and prenatal diagnostics. Find a role that fits from the openings below and apply directly.
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UCI Health is one of California's largest academic health systems and the clinical enterprise of the University of California, Irvine. Established on July 1, 1976, UCI Health has grown into a 1,461-bed health system that includes UCI Health - Orange, UCI Health - Irvine, four Community Network hospitals and a growing network of ambulatory care centers across Orange and Los Angeles counties.
As Orange County’s only academic health systems, UCI Health is home to the only National Cancer Institute-designated comprehensive cancer center based in the county, the region’s only American College of Surgeons-verified Level I adult and Level II pediatric trauma center, American College of Emergency Physicians Gold Level 1 Geriatric Emergency Department and a nationally recognized regional burn center verified by the American Burn Association. Powered by UC Irvine, UCI Health serves 5.6 million people across Orange County, western Riverside County and southeast Los Angeles County through excellence in patient care, research and medical education.
Under the general supervision of the Clinical Manager, incumbents will independently perform a wide variety of technical procedures in Clinical Cytogenetics and Genomics section of the Department of Pathology and Laboratory medicine. Other responsibilities include method development-modification-parallel testing, repair of laboratory instruments, sample processing, reagent preparation, data entry. On a daily basis, incumbents will assess overall workload for any area that needs help. All Clinical Cytogenetics Laboratory Scientists may process specimens, perform waived and non-waived testing without direct and constant supervision, and report results without supervisor or director review for the tests that are within their scope of licensure and for which they have been trained and deemed competent.
Qualifications: Required Qualifications:- Thorough knowledge of all relevant sub-specialty area industry, health and safety, federal, and state regulations.
- Skill and ability to perform mathematical calculations to include: adding, subtracting, multiplying, and dividing whole numbers, fractions, and decimals with and without a calculator to derive results.
- Must possess the skill, knowledge and ability essential to the successful performance of assigned duties
- Must demonstrate customer service skills appropriate to the job
- Must be willing to testify in court regarding testing activities if subpoenaed.
- Must be able to differentiate variations in color
- Exhibits interpersonal skills to independently convey information with authority, handle highly sensitive matters and interact with high level contacts from other organizations.
- Excellent written and verbal communication skills in English
- Excellent customer service skills
- Excellent analytical and problem solving skills.
- Demonstrates knowledge of laboratory concepts, new methodologies and advances in the field of specimen processing, automation, and procedures. Ability to apply principles in a clinical laboratory setting.
- Current California state Cytogenetics CLS License.
- Bachelors' degree or equivalent combination of education and experience
- At least 10 years of laboratory experience in both karyotype and FISH study of cancer samples.
- Ability to use laboratory's application programs. Skill and ability to perform data checks using queries, visual review and other appropriate means to verify data accuracy.
- Ability to respond clearly, concisely, and cooperatively to questions from other technologists, unlicensed staff, or supervisory staff regarding how procedures/duties were or should be performed, validity of test results, etc.
- Ability to organize assignments and laboratory operations in an efficient and effective manner. Highly developed personal organizational skills. Knowledge of quality assurance methods and ability to apply principles to design quality systems.
- Ability to maintain a work pace appropriate to the workload
- Ability to evaluate issues and identify solutions within defined procedures and policies. Demonstrated ability to solve problems and suggest solutions through critical thinking process.
- Ability to establish and maintain effective working relationships across the Health System
- Ability to establish & maintain effective working relationships across the Health System
Preferred Qualifications:
- Knowledge of University and medical center organizations, policies, procedures and forms
- Knowledge of Clinical Laboratory, medical center, HR and UC policies and processes.
Total Rewards
We offer a wealth of benefits to make working at UCI even more rewarding. These benefits may include medical insurance, sick and vacation time, retirement savings plans, and access to a number of discounts and perks. Please utilize the links listed here to learn more about our compensation practices and benefits.
Conditions of Employment:
The University of California, Irvine (UCI) seeks to provide a safe and healthy environment for the entire UCI community. As part of this commitment, all applicants who accept an offer of employment must comply with the following conditions of employment:
- Background Check and Live Scan
- Employment Misconduct*
- Legal Right to Work in the United States
- Vaccination Policies
- Smoking and Tobacco Policy
- Drug Free Environment
- Misconduct Disclosure Requirement: As a condition of employment, the final candidate who accepts a conditional offer of employment will be required to disclose if they have been subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct; received notice of any allegations or are currently the subject of any administrative or disciplinary proceedings involving misconduct; have left a position after receiving notice of allegations or while under investigation in an administrative or disciplinary proceeding involving misconduct; or have filed an appeal of a finding of misconduct with a previous employer.
The following additional conditions may apply, some of which are dependent upon business unit or job specific requirements.
- California Child Abuse and Neglect Reporting Act
- E-Verify
- Pre-Placement Health Evaluation
Details of each policy may be reviewed by visiting the following page: https://hr.uci.edu/new-hire/conditions-of-employment.php
Closing Statement:
The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC Anti-Discrimination Policy.
We are committed to attracting and retaining a diverse workforce along with honoring unique experiences, perspectives, and identities. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable, and welcoming.
UCI provides reasonable accommodations for applicants with disabilities upon request. For more information, please contact UCI's Employee Experience Center (EEC) at eec@uci.edu or at (949) 824-0500, Monday - Friday from 8:30 a.m. - 5:00 p.m.
UCI Health is one of California's largest academic health systems and the clinical enterprise of the University of California, Irvine. Established on July 1, 1976, UCI Health has grown into a 1,461-bed health system that includes UCI Health - Orange, UCI Health - Irvine, four Community Network hospitals and a growing network of ambulatory care centers across Orange and Los Angeles counties.
As Orange County’s only academic health systems, UCI Health is home to the only National Cancer Institute-designated comprehensive cancer center based in the county, the region’s only American College of Surgeons-verified Level I adult and Level II pediatric trauma center, American College of Emergency Physicians Gold Level 1 Geriatric Emergency Department and a nationally recognized regional burn center verified by the American Burn Association. Powered by UC Irvine, UCI Health serves 5.6 million people across Orange County, western Riverside County and southeast Los Angeles County through excellence in patient care, research and medical education.
Under the general supervision of the Clinical Manager, incumbents will independently perform a wide variety of technical procedures in Clinical Cytogenetics and Genomics section of the Department of Pathology and Laboratory medicine. Other responsibilities include method development-modification-parallel testing, repair of laboratory instruments, sample processing, reagent preparation, data entry. On a daily basis, incumbents will assess overall workload for any area that needs help. All Clinical Cytogenetics Laboratory Scientists may process specimens, perform waived and non-waived testing without direct and constant supervision, and report results without supervisor or director review for the tests that are within their scope of licensure and for which they have been trained and deemed competent.
Qualifications: Required Qualifications:- Thorough knowledge of all relevant sub-specialty area industry, health and safety, federal, and state regulations.
- Skill and ability to perform mathematical calculations to include: adding, subtracting, multiplying, and dividing whole numbers, fractions, and decimals with and without a calculator to derive results.
- Must possess the skill, knowledge and ability essential to the successful performance of assigned duties
- Must demonstrate customer service skills appropriate to the job
- Must be willing to testify in court regarding testing activities if subpoenaed.
- Must be able to differentiate variations in color
- Exhibits interpersonal skills to independently convey information with authority, handle highly sensitive matters and interact with high level contacts from other organizations.
- Excellent written and verbal communication skills in English
- Excellent customer service skills
- Excellent analytical and problem solving skills.
- Demonstrates knowledge of laboratory concepts, new methodologies and advances in the field of specimen processing, automation, and procedures. Ability to apply principles in a clinical laboratory setting.
- Current California state Cytogenetics CLS License.
- Bachelors' degree or equivalent combination of education and experience
- At least 10 years of laboratory experience in both karyotype and FISH study of cancer samples.
- Ability to use laboratory's application programs. Skill and ability to perform data checks using queries, visual review and other appropriate means to verify data accuracy.
- Ability to respond clearly, concisely, and cooperatively to questions from other technologists, unlicensed staff, or supervisory staff regarding how procedures/duties were or should be performed, validity of test results, etc.
- Ability to organize assignments and laboratory operations in an efficient and effective manner. Highly developed personal organizational skills. Knowledge of quality assurance methods and ability to apply principles to design quality systems.
- Ability to maintain a work pace appropriate to the workload
- Ability to evaluate issues and identify solutions within defined procedures and policies. Demonstrated ability to solve problems and suggest solutions through critical thinking process.
- Ability to establish and maintain effective working relationships across the Health System
- Ability to establish & maintain effective working relationships across the Health System
Preferred Qualifications:
- Knowledge of University and medical center organizations, policies, procedures and forms
- Knowledge of Clinical Laboratory, medical center, HR and UC policies and processes.
Total Rewards
We offer a wealth of benefits to make working at UCI even more rewarding. These benefits may include medical insurance, sick and vacation time, retirement savings plans, and access to a number of discounts and perks. Please utilize the links listed here to learn more about our compensation practices and benefits.
Conditions of Employment:
The University of California, Irvine (UCI) seeks to provide a safe and healthy environment for the entire UCI community. As part of this commitment, all applicants who accept an offer of employment must comply with the following conditions of employment:
- Background Check and Live Scan
- Employment Misconduct*
- Legal Right to Work in the United States
- Vaccination Policies
- Smoking and Tobacco Policy
- Drug Free Environment
- Misconduct Disclosure Requirement: As a condition of employment, the final candidate who accepts a conditional offer of employment will be required to disclose if they have been subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct; received notice of any allegations or are currently the subject of any administrative or disciplinary proceedings involving misconduct; have left a position after receiving notice of allegations or while under investigation in an administrative or disciplinary proceeding involving misconduct; or have filed an appeal of a finding of misconduct with a previous employer.
The following additional conditions may apply, some of which are dependent upon business unit or job specific requirements.
- California Child Abuse and Neglect Reporting Act
- E-Verify
- Pre-Placement Health Evaluation
Details of each policy may be reviewed by visiting the following page: https://hr.uci.edu/new-hire/conditions-of-employment.php
Closing Statement:
The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC Anti-Discrimination Policy.
We are committed to attracting and retaining a diverse workforce along with honoring unique experiences, perspectives, and identities. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable, and welcoming.
UCI provides reasonable accommodations for applicants with disabilities upon request. For more information, please contact UCI's Employee Experience Center (EEC) at eec@uci.edu or at (949) 824-0500, Monday - Friday from 8:30 a.m. - 5:00 p.m.
Cytogenetic Technologist Jobs by Experience Level
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Find Cytogenetic Technologist JobsCytogenetic Technologist Job Market
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
- Medical Devices
- Biotechnology & Pharmaceuticals
What Employers Look For
The qualifications that appear most often in cytogenetic technologist jobs.
- Bachelor's degree in biology, genetics, or a closely related life science field
- CG(ASCP) or CLSp(CG) certification from a recognized credentialing body
- Proficiency in karyotyping, FISH analysis, and chromosome banding techniques
- Experience with cytogenetic analysis software such as Applied Spectral Imaging or Leica CytoVision
- Minimum one to two years of clinical cytogenetics laboratory experience
- Familiarity with ISCN nomenclature and laboratory quality assurance documentation standards
Tips for Your Cytogenetic Technologist Job Search
Tailor your resume to cytogenetics-specific tools
List the chromosome analysis software and karyotyping platforms you've used, such as Applied Spectral Imaging or Leica systems, alongside your banding techniques. Generic lab skills don't differentiate you the way instrument-specific experience does.
Highlight your ASCP or NCA certification prominently
Employers filter for CG(ASCP) or CLSp(CG) credentials before reviewing anything else. Place your certification immediately after your name in the header so it's visible in the first second, not buried in a separate section.
Apply early to roles that fit
Migrate Mate lists cytogenetic technologist openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Target postings by specimen type and setting
Distinguish between constitutional, oncology, and prenatal cytogenetics when searching. A prenatal-focused lab and an oncology center require different case experience, so match your application narrative to the specimen types you've actually worked with.
Prepare to discuss your FISH and microarray case volume
Interviewers in this field routinely ask how many FISH cases or microarray analyses you've processed independently. Know your approximate case numbers and be ready to describe the complexity of cases you've handled without supervision.
Follow up referencing your technical throughput
When sending a post-interview thank-you, reference a specific technical point from the conversation, such as your experience with a particular staining protocol or your comfort with high-volume karyotype analysis. Generic follow-ups get ignored in highly specialized labs.
Cytogenetic Technologist Jobs: Frequently Asked Questions
Which companies are hiring the most cytogenetic technologists?
The companies hiring the most cytogenetic technologists right now include Quest Diagnostics, BayCare Health System, and Allegheny Health Network, with the largest share of openings in Florida, California, and Michigan, based on current listings on Migrate Mate as of September 2026. Academic medical centers and large reference laboratory networks tend to post the most consistently throughout the year.
How many cytogenetic technologist jobs are remote?
About 0% of cytogenetic technologist openings are fully remote or hybrid as of September 2026, reflecting the hands-on nature of most cytogenetics bench work. Administrative roles, case review positions, and laboratory director-level oversight are the sub-areas most likely to accommodate remote or hybrid arrangements.
How do you become a cytogenetic technologist?
You become a cytogenetic technologist by earning a bachelor's degree in biology, genetics, or a related science, then completing a clinical cytogenetics training program accredited through NAACLS or an equivalent pathway. After training, you sit for the CG(ASCP) or CLSp(CG) certification exam. Most employers require certification before hiring, so completing an accredited internship or clinical rotation that prepares you for the exam is the most direct route into the field.
Can you get a cytogenetic technologist job with little or no experience?
You can get hired as a cytogenetic technologist with limited experience if you've completed an accredited cytogenetics training program and hold your certification, since labs often count structured clinical rotations toward their experience requirement. Entry-level roles at reference labs or academic medical centers are the most accessible starting points. Emphasizing your karyotyping case volume from training and any coursework in FISH or microarray analysis strengthens an application even without independent work history.
What does the cytogenetic technologist interview process look like?
The cytogenetic technologist interview process typically involves an initial phone or video screen with HR or a lab manager, followed by a technical interview where you'll be asked to walk through your karyotyping workflow, FISH case experience, and familiarity with ISCN nomenclature. Some labs include a practical component where you review sample karyotype images or describe how you'd handle an abnormal finding. A final interview with the laboratory director or a panel is common before an offer is extended.
Where can I find and apply to cytogenetic technologist jobs?
You can find and apply to cytogenetic technologist jobs on Migrate Mate, which lists current openings from across the United States. Search the listings to find roles that match your experience, certification level, and preferred setting, then apply directly to each listing that fits.
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