Full Stack Engineer Jobs in Missouri
Full Stack Engineer jobs in Missouri are concentrated in St. Louis and Kansas City, where companies like Mastercard, Cerner (Oracle Health), and Edward Jones maintain large engineering teams with consistent demand for front-end, back-end, and cloud-native development skills. The market runs from entry-level associate engineers through senior and staff-level roles, with the strongest hiring activity in fintech, healthcare technology, and enterprise software. React, Node.js, and AWS expertise stand out as the most sought-after specialties across Missouri postings. Scan the live roles below and apply to whichever ones fit.
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EngineeringContractorMexicoRemote
Job Type: Contractor; 6-12 months
Job Location: Remote; ability to work on Eastern Standard Time
About us:
ACTO is an Intelligent Field Excellence (IFE) platform built for life sciences that unifies human intelligence with empathetic AI to help Sales, Medical, Market Access, and Marketing teams improve customer engagement and brand performance. With ACTO, biopharma companies can ensure field professionals are always competent, confident, and credible in face-to-face HCP interactions, while providing senior leaders and frontline managers with the insight they need to drive continuous field force effectiveness. As a validated platform compliant with FDA 21 CFR Part 11 and SOC 2 Type II certified, ACTO is the trusted partner for intelligent field excellence in the life sciences industry.
Role Summary:
We are seeking a talented Laravel / Vue Developer to design, develop, and maintain modern web applications that power ACTO’s Intelligent Field Excellence platform. You will collaborate closely with product managers and designers to deliver high-quality features, ensure performance and scalability, and build a seamless user experience across our applications. An important part of this role is contributing to ACTO’s AI-powered solutions, including integrating with large language model APIs and AWS Bedrock to bring intelligent experiences into our products.
In this role, you will be responsible for:
- Designing, building, and maintaining secure, scalable web applications using Laravel (backend) and Vue.js (frontend).
- Building and consuming RESTful APIs and integrating with third-party AI services (e.g., AWS Bedrock, OpenAI, Anthropic).
- Writing clean, maintainable, and testable code following industry best practices.
- Developing responsive, intuitive user interfaces with Vue.js, Vuex (state management), and modern component libraries.
- Working with relational databases such as MySQL or PostgreSQL, including schema design and query optimization.
- Implementing features that leverage generative AI to enhance user experiences.
- Ensuring code quality through automated testing and peer reviews.
- Collaborating in Agile development cycles with cross-functional teams.
To be successful in this role, you’ll need:
- 4+ years of professional experience in full-stack web development.
- Strong expertise with Laravel (or another modern PHP framework) and Vue.js.
- Experience working with AI and cloud-based AI services such as AWS Bedrock.
- Solid understanding of RESTful API design and implementation.
- Experience with relational databases (MySQL, PostgreSQL) and query optimization.
- Proficiency in HTML5, CSS3 (Sass/Tailwind), and JavaScript/ES6+.
- Familiarity with Git workflows, CI/CD pipelines, and Agile development environments.
- Strong problem-solving skills and ability to work independently and collaboratively.
- Good verbal and written communication in English.
Bonus points if you have:
- Experience with Docker, Kubernetes, or other containerization/orchestration tools.
- Knowledge of AWS services beyond Bedrock (e.g., S3, RDS, EC2, Lambda).
- Familiarity with testing frameworks such as PHPUnit, Pest, or Jest.
- Previous experience in the Life Sciences or healthcare technology sector.
- Exposure to startup or high-growth SaaS environments.
What you’ll enjoy about ACTO:
- Industry-leading, multiple award-winning technology.
- Competitive compensation package.
- Being part of a mission-driven organization with the ability to drive solutions that focus on improving patient outcomes.
- Results-driven and collaborative culture. Remote work flexibility.
At ACTO we believe diverse and inclusive teams perform better. We are an equal opportunity employer and are committed to working with applicants requesting accommodations during our interview process.
We may use AI-powered tools during parts of our hiring process to help review applications and support candidate communication. These tools are designed to assist our team, but all final hiring decisions are made by human recruiters and hiring managers. If you have any questions or concerns about this process, please let us know.
We thank everyone for their interest in ACTO, only those applicants that have been selected for an interview will be contacted.
See All 15 Full Stack Engineer Jobs in Missouri
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Find Full Stack Engineer JobsFull Stack Engineer Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Full Stack Engineer Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Technology & Software
- Banking & Financial Services
- Consulting & Professional Services
What Missouri Employers Look For
The qualifications that appear most often in full stack engineer jobs across Missouri.
- Bachelor's degree in computer science, software engineering, or a related technical field
- Proficiency in at least one front-end framework such as React, Angular, or Vue.js
- Hands-on experience with back-end languages including Node.js, Java, Python, or Go
- Familiarity with cloud platforms, particularly AWS, Azure, or Google Cloud
- Experience designing and integrating RESTful APIs and working with relational databases
- Strong version control practices using Git within a collaborative team environment
Full Stack Engineer Jobs in Missouri: Frequently Asked Questions
How do you become a full stack engineer in Missouri?
Full stack engineering in Missouri has no state-issued license or registration requirement, so the path runs through education and demonstrated skill. Most employers expect a bachelor's degree in computer science or software engineering, though graduates of accredited coding programs at institutions like Maryville University or the University of Missouri are competitive. Building a portfolio of projects covering both front-end and back-end work is the clearest signal for Missouri hiring managers.
How much do full stack engineers make in Missouri?
Full stack engineers in Missouri earn a median of about $126,120 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $72,570 for the lowest 10% to over $169,340 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire full stack engineers in Missouri?
Companies currently hiring full stack engineers in Missouri include Peraton, Equifax, and Infosys, per current listings on Migrate Mate as of August 2026. Missouri's fintech and healthcare technology sectors, anchored in St. Louis and Kansas City, produce some of the state's most consistent full stack engineering demand.
Which Missouri cities have the most full stack engineer jobs?
St. Louis, Kansas City, and Mexico lead Missouri for full stack engineer openings. St. Louis drives volume through its dense cluster of financial services, healthcare IT, and enterprise software companies, while Kansas City's growing startup scene and presence of large insurers and logistics firms sustain steady hiring across both metros.
Are there remote full stack engineer jobs in Missouri?
Yes, and more than most fields. About 78% of full stack engineer openings tied to Missouri are remote or hybrid as of August 2026, reflecting how well the work adapts to distributed teams. Roles centered on front-end development and API integration tend to appear fully remote most often, while positions involving on-site infrastructure or regulated healthcare data are more likely to require some in-office presence.
How can I get hired as a full stack engineer in Missouri with little or no experience?
The most realistic entry point is an associate or junior engineer role at a Missouri-based technology consultancy or mid-size software company, where structured onboarding is common. Companies like World Wide Technology in St. Louis and larger healthcare IT firms in Kansas City run new-grad and apprenticeship pipelines that accept candidates without professional experience. A portfolio demonstrating full-stack projects, contributions to open-source repositories, or completion of a recognized coding credential strengthens any application significantly.
Where can I find and apply to full stack engineer jobs in Missouri?
You can find and apply to full stack engineer jobs in Missouri on Migrate Mate, which lists current openings tied to the state. Search the roles available, identify the ones that fit your experience and location preference, and apply directly through each listing.
See All 15 Full Stack Engineer Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
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