H-1B Visa Strategic Alliance Manager Jobs
Strategic Alliance Manager roles qualify for H-1B visa sponsorship as specialty occupations requiring a bachelor's degree in business, marketing, or a related field. Employers in tech, SaaS, and enterprise software file LCAs with the DOL before sponsoring, and most active sponsors run H-1B filings each April for the October 1 cap-subject start date.
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ProFound™ Therapeutics is a biotechnology company discovering novel proteins across the expanded human proteome to unlock transformative drug targets and first-in-class medicines. The company's proprietary ProFoundry™ Platform integrates state-of-the-art protein detection, validation, and computational technologies to systematically identify and characterize previously unknown proteins and validate their therapeutic potential. This approach has generated a rapidly expanding portfolio of novel targets and programs advancing toward the clinic, along with strategic collaborations with leading pharmaceutical partners. Together, these efforts support the development of breakthrough treatments across a broad range of disease areas.
Position Summary
ProFound Therapeutics is seeking a Senior Director, Alliance & Program Management to serve as an operational and strategic partner to the Chief Operating Officer, leadership team, and program teams.
This role has two primary responsibilities: (1) serving as the day-to-day operational leader for ProFound's strategic pharmaceutical collaborations and (2) building the company's portfolio and program management capabilities. The role ensures successful alliance and program execution while developing the governance, planning processes, and operating systems that enable disciplined execution across the company's growing portfolio. This is a highly visible role requiring exceptional judgment, operational rigor, and the ability to influence without authority. The successful candidate will lead day-to-day alliance execution, enable governance, implement practical program management systems, and partner with scientific leadership to translate decisions into disciplined execution and ensure that programs remain aligned on objectives, timelines, budget, risks, and resource needs.
The ideal candidate is an experienced biotechnology operator who combines strategic thinking with hands-on execution. They thrive in a lean, entrepreneurial environment where priorities evolve rapidly and success depends on bringing structure to complexity, building practical solutions, fostering collaboration, and driving accountability across highly matrixed teams.
Key Responsibilities
Alliance Management
- Serve as the primary Alliance Manager and operational leader for ProFound's strategic pharmaceutical collaborations, ensuring successful execution of scientific objectives, governance activities, and contractual commitments.
- Build trusted relationships across partner organizations while coordinating cross-functional scientific, legal, finance, IP, and operational teams to drive alliance execution.
- Lead Joint Steering Committees (JSCs) and other governance forums, ensuring meetings are well prepared, decisions documented, and actions successfully executed.
- Partner with Business Development to help structure new alliances for successful execution.
- Translate collaboration agreements into executable operating plans, proactively managing milestones, deliverables, risks, issues, and partner expectations.
- Monitor alliance health and performance, resolving conflicts constructively and providing executive leadership with clear visibility into key risks and opportunities.
- Build credibility through exceptional execution, proactive communication, sound judgment, and effective stakeholder management.
Program Management
- Build and continuously improve ProFound's portfolio and program management capabilities, including governance, tools, and operating processes.
- Lead integrated program management across discovery and early development programs, ensuring visibility into progress, risks, and resource needs.
- Train and support scientific teams in adopting practical project management tools and consistent execution practices.
- Partner with scientific leadership to implement stage-gate processes, governance frameworks, and portfolio reporting that support timely, high-quality decisions.
- Partner with Finance to integrate program plans, budgets, and decision points, framing up options for timely investment, tradeoff, and resource allocation decisions.
- Facilitate cross-functional program reviews, ensuring alignment, accountability, and effective follow-through on key decisions and actions.
- Foster an operating culture that balances executional discipline with the agility of a growing biotechnology company.
Portfolio Strategy, Planning & Governance
- Partner with executive leadership to drive portfolio prioritization, governance, and strategic investment decisions across pipeline and platform initiatives.
- Support annual strategic planning, Long-Range Planning (LRP), and portfolio planning by coordinating program assumptions, milestones, timelines, and resource inputs.
- Develop executive dashboards and portfolio reporting that improve visibility into organizational priorities, execution, and performance.
- Provide program management support for executive governance meetings and other high-priority cross-functional initiatives.
Qualifications
Experience
- Ph.D. or M.S. in life sciences, or MBA with at least 5 years of direct experience working closely with scientific teams in a biotech or pharmaceutical setting.
- 10-15+ years' experience in biotech or pharma alliance management, portfolio management, program management, and operational leadership.
- Demonstrated success managing complex external partnerships, including governance, contractual obligations, and relationship management requiring judgement and influence across multiple stakeholders.
- Hands-on experience leading program management across multi-program biotech portfolios, from early discovery through translational development.
- Proven track record of building portfolio management processes, governance models, and project management capabilities within a growing biotechnology company.
- Experience supporting portfolio prioritization, strategic planning, and executive governance.
- Experience working closely with scientific leadership and large pharma partners.
Capabilities
- Exceptional judgment and credibility, with a demonstrated ability to influence senior scientific leaders and external partners while navigating complex, cross-organizational decisions.
- Outstanding operational rigor and systems thinking, with the ability to build practical governance processes, tools, and execution frameworks that improve accountability and visibility without creating unnecessary bureaucracy.
- Excellent communication and facilitation skills, translating complex scientific, operational, and business issues into clear decisions, action plans, and executive-level communications.
- Proven ability to influence without authority, build consensus, proactively manage stakeholders, and drive accountability across highly matrixed organizations.
- Skilled at resolving conflict constructively, balancing diplomacy with accountability while building trusted relationships with internal teams and external partners.
- Highly organized and detail-oriented, with the ability to seamlessly shift between execution details and strategic organizational priorities.
- Collaborative, low-ego leader with a solutions-oriented mindset and a demonstrated ability to build trust across functions and organizations.
- Thrives in lean, fast-paced, entrepreneurial environments, demonstrating adaptability, resourcefulness, and a strong bias toward action.
Values and Behaviors
We are seeking leaders who demonstrate strategic thinking, extreme teamwork, executional excellence, adaptability, and a commitment to inclusion and diversity. We particularly value candidates who combine intellectual curiosity with a strong bias toward action - who are as comfortable asking a question as they are driving a workstream to close. We encourage candidates with passion, leadership capability, and depth across these functional areas - even if not meeting every requirement - to apply.
ABOUT FLAGSHIP PIONEERING:
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies.
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Compensation
- The salary range for this role is $217,000 - $275,000. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. ProFound Therapeutics, Inc. currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on ProFound Therapeutics, Inc.'s good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
Company Summary
ProFound™ Therapeutics is a biotechnology company discovering novel proteins across the expanded human proteome to unlock transformative drug targets and first-in-class medicines. The company's proprietary ProFoundry™ Platform integrates state-of-the-art protein detection, validation, and computational technologies to systematically identify and characterize previously unknown proteins and validate their therapeutic potential. This approach has generated a rapidly expanding portfolio of novel targets and programs advancing toward the clinic, along with strategic collaborations with leading pharmaceutical partners. Together, these efforts support the development of breakthrough treatments across a broad range of disease areas.
Position Summary
ProFound Therapeutics is seeking a Senior Director, Alliance & Program Management to serve as an operational and strategic partner to the Chief Operating Officer, leadership team, and program teams.
This role has two primary responsibilities: (1) serving as the day-to-day operational leader for ProFound's strategic pharmaceutical collaborations and (2) building the company's portfolio and program management capabilities. The role ensures successful alliance and program execution while developing the governance, planning processes, and operating systems that enable disciplined execution across the company's growing portfolio. This is a highly visible role requiring exceptional judgment, operational rigor, and the ability to influence without authority. The successful candidate will lead day-to-day alliance execution, enable governance, implement practical program management systems, and partner with scientific leadership to translate decisions into disciplined execution and ensure that programs remain aligned on objectives, timelines, budget, risks, and resource needs.
The ideal candidate is an experienced biotechnology operator who combines strategic thinking with hands-on execution. They thrive in a lean, entrepreneurial environment where priorities evolve rapidly and success depends on bringing structure to complexity, building practical solutions, fostering collaboration, and driving accountability across highly matrixed teams.
Key Responsibilities
Alliance Management
- Serve as the primary Alliance Manager and operational leader for ProFound's strategic pharmaceutical collaborations, ensuring successful execution of scientific objectives, governance activities, and contractual commitments.
- Build trusted relationships across partner organizations while coordinating cross-functional scientific, legal, finance, IP, and operational teams to drive alliance execution.
- Lead Joint Steering Committees (JSCs) and other governance forums, ensuring meetings are well prepared, decisions documented, and actions successfully executed.
- Partner with Business Development to help structure new alliances for successful execution.
- Translate collaboration agreements into executable operating plans, proactively managing milestones, deliverables, risks, issues, and partner expectations.
- Monitor alliance health and performance, resolving conflicts constructively and providing executive leadership with clear visibility into key risks and opportunities.
- Build credibility through exceptional execution, proactive communication, sound judgment, and effective stakeholder management.
Program Management
- Build and continuously improve ProFound's portfolio and program management capabilities, including governance, tools, and operating processes.
- Lead integrated program management across discovery and early development programs, ensuring visibility into progress, risks, and resource needs.
- Train and support scientific teams in adopting practical project management tools and consistent execution practices.
- Partner with scientific leadership to implement stage-gate processes, governance frameworks, and portfolio reporting that support timely, high-quality decisions.
- Partner with Finance to integrate program plans, budgets, and decision points, framing up options for timely investment, tradeoff, and resource allocation decisions.
- Facilitate cross-functional program reviews, ensuring alignment, accountability, and effective follow-through on key decisions and actions.
- Foster an operating culture that balances executional discipline with the agility of a growing biotechnology company.
Portfolio Strategy, Planning & Governance
- Partner with executive leadership to drive portfolio prioritization, governance, and strategic investment decisions across pipeline and platform initiatives.
- Support annual strategic planning, Long-Range Planning (LRP), and portfolio planning by coordinating program assumptions, milestones, timelines, and resource inputs.
- Develop executive dashboards and portfolio reporting that improve visibility into organizational priorities, execution, and performance.
- Provide program management support for executive governance meetings and other high-priority cross-functional initiatives.
Qualifications
Experience
- Ph.D. or M.S. in life sciences, or MBA with at least 5 years of direct experience working closely with scientific teams in a biotech or pharmaceutical setting.
- 10-15+ years' experience in biotech or pharma alliance management, portfolio management, program management, and operational leadership.
- Demonstrated success managing complex external partnerships, including governance, contractual obligations, and relationship management requiring judgement and influence across multiple stakeholders.
- Hands-on experience leading program management across multi-program biotech portfolios, from early discovery through translational development.
- Proven track record of building portfolio management processes, governance models, and project management capabilities within a growing biotechnology company.
- Experience supporting portfolio prioritization, strategic planning, and executive governance.
- Experience working closely with scientific leadership and large pharma partners.
Capabilities
- Exceptional judgment and credibility, with a demonstrated ability to influence senior scientific leaders and external partners while navigating complex, cross-organizational decisions.
- Outstanding operational rigor and systems thinking, with the ability to build practical governance processes, tools, and execution frameworks that improve accountability and visibility without creating unnecessary bureaucracy.
- Excellent communication and facilitation skills, translating complex scientific, operational, and business issues into clear decisions, action plans, and executive-level communications.
- Proven ability to influence without authority, build consensus, proactively manage stakeholders, and drive accountability across highly matrixed organizations.
- Skilled at resolving conflict constructively, balancing diplomacy with accountability while building trusted relationships with internal teams and external partners.
- Highly organized and detail-oriented, with the ability to seamlessly shift between execution details and strategic organizational priorities.
- Collaborative, low-ego leader with a solutions-oriented mindset and a demonstrated ability to build trust across functions and organizations.
- Thrives in lean, fast-paced, entrepreneurial environments, demonstrating adaptability, resourcefulness, and a strong bias toward action.
Values and Behaviors
We are seeking leaders who demonstrate strategic thinking, extreme teamwork, executional excellence, adaptability, and a commitment to inclusion and diversity. We particularly value candidates who combine intellectual curiosity with a strong bias toward action - who are as comfortable asking a question as they are driving a workstream to close. We encourage candidates with passion, leadership capability, and depth across these functional areas - even if not meeting every requirement - to apply.
ABOUT FLAGSHIP PIONEERING:
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies.
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Compensation
- The salary range for this role is $217,000 - $275,000. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. ProFound Therapeutics, Inc. currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on ProFound Therapeutics, Inc.'s good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
See all 49+ H-1B Visa Strategic Alliance Manager Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new H-1B Visa Strategic Alliance Manager Jobs.
Get Access To All JobsTips for Finding H-1B Visa Sponsorship as a Strategic Alliance Manager
Frame your degree for specialty occupation
USCIS evaluates whether your degree field directly relates to alliance management duties. A business, marketing, or international relations degree maps cleanly. If your degree is in an unrelated field, document how coursework and experience align to the role's core functions.
Use LCA data to target active sponsors
DOL Labor Condition Application filings are public record. Search OFLC Wage Search for alliance manager job titles to identify companies that have filed recently, which signals an active sponsorship infrastructure rather than a one-off hire.
Search verified sponsors on Migrate Mate
Migrate Mate filters Strategic Alliance Manager roles by employers with confirmed H-1B filing history, so you're applying to companies that already have sponsorship processes in place rather than discovering their position late in the interview cycle.
Clarify partnership scope in your application
Alliance Manager roles span ISV partnerships, reseller channels, and co-sell programs. Specifying the type of partnerships you manage helps employers match your profile to the correct SOC code on the LCA, which affects prevailing wage tier and petition strength.
Time your offer conversations around the cap
Cap-subject H-1B petitions have a hard April filing deadline for an October 1 start. If you're negotiating an offer in late Q3 or Q4, confirm whether the employer plans to file in the next registration window or wait a full cycle before accepting.
Verify cap-exempt employer eligibility early
Universities, nonprofit research organizations, and certain government-affiliated entities are cap-exempt and can sponsor H-1B workers outside the annual lottery. If an alliance manager role is posted by one of these employers, USCIS allows filing year-round with no registration requirement.
H-1B Visa Strategic Alliance Manager: Frequently Asked Questions
Does a Strategic Alliance Manager role qualify as a specialty occupation for H-1B purposes?
Yes, provided the employer documents that the role requires a bachelor's degree or higher in a specific field such as business, marketing, or a related discipline. Roles focused on ISV partnerships, enterprise co-sell programs, or technology alliances typically meet the specialty occupation standard because the work requires theoretical and practical application of a specialized body of knowledge. Vague job descriptions that accept any degree field can create problems at adjudication.
How do I find Strategic Alliance Manager employers that actively sponsor H-1B visas?
Migrate Mate shows Strategic Alliance Manager roles filtered by employers with verified H-1B filing history. You can also cross-reference DOL's OFLC disclosure data to confirm a company has filed LCAs for this job title previously. Tech companies, SaaS vendors, and cloud platform providers appear most frequently in LCA filings for alliance-focused roles.
Which SOC code typically applies to Strategic Alliance Manager positions on an LCA?
Most Strategic Alliance Manager filings use SOC 11-2021 (Marketing Managers) or SOC 11-2022 (Sales Managers), depending on whether the role emphasizes partner marketing programs or channel revenue. The employer's HR or immigration counsel determines the SOC code, and it directly sets the prevailing wage tier on the LCA. You can check wage levels for each code by region using the OFLC Wage Search.
Can I transfer my H-1B to a new Strategic Alliance Manager role without restarting the process?
Yes. Under H-1B portability rules, you can start working for a new employer as soon as the transfer petition is filed with USCIS, as long as your current H-1B has been approved for at least 180 days. The new employer files a new I-129 petition and LCA but you don't re-enter the lottery. Confirm the new role falls under the same specialty occupation category as your existing approval to avoid an RFE.
Does the type of alliance program I manage affect H-1B sponsorship eligibility?
It can affect how the employer structures the LCA and which SOC code they use, but the underlying eligibility turns on degree requirement rather than program type. Roles managing technology reseller channels, cloud marketplace partnerships, or OEM agreements all qualify when the employer can show the work requires a specialized degree. Roles that are primarily sales-quota-focused with no specialized knowledge requirement are harder to defend as specialty occupation.