Histotechnician Jobs
Histotechnician jobs are open across hospitals, commercial reference labs, academic medical centers, and research institutions, at every level from entry-level to senior and lead, with specializations in immunohistochemistry, frozen section processing, and special staining. See the openings below and apply to the ones that match your experience.
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The Histotechnician III prepares tissue specimens for surgical pathology examination. This includes evaluating the acceptability of the specimens, properly embedding the processed tissue, cutting/sectioning the specimens, and staining the slides using automated or manual methods.
- Performs embedding and cutting on both biopsies and large surgical specimens, while consistently meeting quality and productivity standards.
- Performs and troubleshoots routine H&E and Special Staining, including Muscle Enzymes.
- Initiates, solves problems, and troubleshoots independently as it pertains to their assigned duties. May be designated a specific area within the lab to oversee instrumentation, policies, procedures, workflows, and any other tasks relevant to specified area.
- Able to perform immunohistochemical (IHC) staining independently. Successfully QC all slides, prepare prep kits and other antibodies, responsible for validations (new lot, new antibody, new instrumentation, new control blocks, etc.), troubleshoot staining errors/quality concerns. Responsible for machine maintenance.
- Performs, troubleshoots, and appropriately assesses quality control reactions for all special stains, muscle enzyme stains and IHC stains; maintains competencies for these tasks.
- Trains students and new employees.
- Assists with writing and updating policies and procedures.
- Maintains knowledge of relevant CAP checklists through active participation in the inspection process.
- Collaborates with department technical and medical leadership to ensure laboratory compliance with all regulatory agencies by established standards.
- Assists with instrument and control tissue validations; supports new assay development as assigned by Supervisor.
- Makes good business decisions based on the needs of the laboratory, pathologists, patients, and other customer segments.
- Contributes to a positive work environment.
- Performs other duties as assigned.
- Complies with all policies and standards.
- For specific duties and responsibilities, refer to documentation provided by the department during orientation.
- Must abide by all requirements to safely and securely maintain Protected Health Information (PHI) for our patients. Annual training, the UH Code of Conduct and UH policies and procedures are in place to address appropriate use of PHI in the workplace.
- Associate's Degree in Histology or in a laboratory science or medical laboratory technology from an accredited institution (Required)
- 2+ years relevant experience in a clinical histology laboratory (Required) and
- 1+ years relevant experience in special stains (Required) and
- less than 1 year of training AND competency in immunohistochemistry (IHC) (Required)
- Basic computer skills (Required proficiency)
- Good organizational skills (Required proficiency)
- Able to multitask (Required proficiency)
- Able to work effectively independently and with other team members (Required proficiency)
- Knowledge of standard lab policy and procedures, safety practices equipment and instrumentation (Required proficiency)
- Knowledge of principals, concepts, and methodology sufficient to perform the full spectrum of histologic preparation of specimens for microscopic evaluation (Required proficiency)
- Knowledge of staining procedures, fixatives, and preparation techniques common to histology laboratories (Required proficiency)
- Knowledge of laboratory safety including standard precautions for handling hazardous chemicals and solutions (Required proficiency)
- Knowledge of CAP/CLIA regulations as they pertain to histopathology (Required proficiency)
- Certification by the American Society of Clinical Pathologists HT(ASCP) (Required Upon Hire)
- Standing Frequently
- Walking Frequently
- Sitting Rarely
- Lifting Frequently up to 50 lbs
- Carrying Frequently up to 50 lbs
- Pushing Frequently up to 50 lbs
- Pulling Frequently up to 50 lbs
- Climbing Occasionally up to 50 lbs
- Balancing Occasionally
- Stooping Frequently
- Kneeling Frequently
- Crouching Frequently
- Crawling Occasionally
- Reaching Frequently
- Handling Frequently
- Grasping Frequently
- Feeling Constantly
- Talking Constantly
- Hearing Constantly
- Repetitive Motions Constantly
- Eye/Hand/Foot Coordination Constantly
- 5%
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Find Histotechnician JobsHistotechnician Job Market
Who's Hiring


Top Industries Hiring
- Healthcare & Medical Services
What Employers Look For
The qualifications that appear most often in histotechnician jobs.
- ASCP certification as HT or HTL required or preferred
- Proficiency with automated tissue processors and rotary microtomes
- Experience performing hematoxylin and eosin staining and special stains
- Familiarity with immunohistochemistry protocols and staining platforms
- Knowledge of CAP accreditation standards and laboratory quality control procedures
- Associate or bachelor's degree in histotechnology or a related biological science
Tips for Your Histotechnician Job Search
Tailor your resume to lab-specific workflows
Hiring managers scan for named techniques and equipment, not generic lab experience. List the exact tissue processors, microtomes, and staining platforms you've operated, and call out any high-volume or specialized case types you've handled, such as bone decalcification or electron microscopy prep.
Lead with your HT or HTL certification
ASCP certification separates your application before a recruiter reads a single bullet point. Place your HT or HTL credential directly after your name in the header, not buried in a separate section, so it's visible at a glance on any applicant tracking system.
Target openings that match your CAP or CLIA exposure
Many postings specify regulatory environment experience. If you've worked in a CAP-accredited or CLIA-certified lab, say so explicitly in your resume summary. Facilities running accreditation cycles prioritize candidates who already understand quality documentation and proficiency testing requirements.
Apply early to roles that fit
Migrate Mate lists histotechnician openings from across the United States in one place, so you can find roles that match and apply directly to each listing. Applying early matters most for high-volume hospital systems, where positions fill quickly once posted.
Prepare a frozen section walk-through for interviews
Interviewers at surgical pathology-heavy facilities almost always probe your intraoperative frozen section workflow. Practice describing your cryostat technique, turnaround time expectations, and how you handle artifact management under time pressure before you walk into any on-site interview.
Negotiate shift differential before accepting any offer
Histotechnician roles frequently include evening, overnight, or weekend rotations with differential pay built into the compensation structure. Ask during the offer stage which shifts the role covers, what the differential rate is, and whether that differential is included in the posted range or added on top.
Histotechnician Jobs: Frequently Asked Questions
Which companies are hiring the most histotechnicians?
The most active employers for histotechnicians right now are Stanford Health Care, LovelyGroup, and Mercy Health, and the most openings are in Texas, California, and South Carolina, based on current listings on Migrate Mate as of August 2026. Large health systems and national reference laboratories tend to post the most consistently throughout the year.
How many histotechnician jobs are remote?
About 0% of histotechnician openings are fully remote or hybrid as of August 2026, reflecting the hands-on nature of most laboratory bench work. The sub-areas most likely to offer remote or hybrid arrangements are digital pathology quality review, image analysis, and laboratory information system coordination roles that don't require physical specimen handling.
How do you become a histotechnician?
You typically complete an accredited histotechnology program or earn a relevant science degree, then gain hands-on laboratory experience in tissue processing, microtomy, and staining. After meeting eligibility requirements, you sit for the ASCP Board of Certification HT exam. Many employers require certification before hire, while others allow candidates to sit for the exam within a set period after starting.
Can you get hired as a histotechnician with little or no experience?
Yes, some hospital and reference lab positions are structured for new graduates or candidates completing their training externship. Highlighting any coursework-based practicum hours, volunteer lab work, or histology-adjacent experience such as phlebotomy or cytology assisting strengthens an entry-level application. Targeting facilities with formal new-grad orientation tracks improves your odds of getting an interview without prior paid experience.
What does the histotechnician interview process look like?
Most histotechnician interviews begin with a phone or video screen focused on certification status and availability. An on-site interview follows, often including a practical skills assessment where you may be asked to demonstrate microtomy technique or describe your staining troubleshooting process. Some facilities also conduct a lab tour and introduce you to the pathology team before making a hiring decision.
Where can I find and apply to histotechnician jobs?
You can find and apply to histotechnician jobs on Migrate Mate, which lists current openings from across the United States. Search for roles that match your certification level, specialization, and preferred location, then apply directly to each listing that fits your background. New positions are added regularly, so checking back often helps you catch openings as soon as they're posted.
See All 46 Histotechnician Jobs
Find roles that match your experience and apply in just a few clicks.
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