Human Resources Assistant Jobs in St. Louis, MO

Human Resources Assistant jobs in St. Louis are concentrated in Clayton, the Central Business District, and the Cortex Innovation Community, with strong demand from healthcare systems, financial services firms, and large universities employing CRB, Sonesta, and Stepful. Hiring is active across these sectors year-round. Find a role that fits below and apply directly.

Find Jobs

Overview

Open roles86
Top employerCRB
Work type50% On-site
Top credentialBachelor's degree
Companies hiring16

Showing 5 of 86+ Human Resources Assistant jobs

CRB
Director, People Operations
We won't show you this job again
CRB
Added 2d ago
Director, People Operations
CRB
St. Louis, Missouri
Compliance & Risk
Program Management
Project Management
Hybrid
Bachelor's degree

Have you applied for this role?

Edward Jones
Senior Human Resources Business Partner
We won't show you this job again
Edward Jones
Added 4d ago
Senior Human Resources Business Partner
Edward Jones
St. Louis, Missouri
Business Strategy
Executive Leadership & C-Suite
Strategy & Corporate Development
$120k - $204k/yr
Hybrid
Bachelor's degree
10,000+

Have you applied for this role?

Grant's Farm
Human Resources Manager
We won't show you this job again
Grant's Farm
Added 1w ago
Human Resources Manager
Grant's Farm
St. Louis, Missouri
Compensation & Benefits
Human Resources
Human Resources (HR) — Generalist
Learning & Development
1,001-5,000

Have you applied for this role?

US Department of Veterans Affairs
VCS - Human Resources Specialist - Performance Management
We won't show you this job again
US Department of Veterans Affairs
Added 1w ago
VCS - Human Resources Specialist - Performance Management
US Department of Veterans Affairs
St. Louis, Missouri
Data Analytics
Data Science
On-Site
Bachelor's degree
10,000+

Have you applied for this role?

Provident Inc / Mary Ryder Home
Human Resources Coordinator
We won't show you this job again
Provident Inc / Mary Ryder Home
Added 1w ago
Human Resources Coordinator
Provident Inc / Mary Ryder Home
St. Louis, Missouri
Business Development
Human Resources (HR) — Generalist
Recruiting & Talent Acquisition
$24.5 - $27.5/hr
Associate Professional in Human Resources
51-200

Have you applied for this role?

See All 86 Human Resources Assistant Jobs in St. Louis

Find roles in St. Louis that match your experience and apply in just a few clicks.

Find Jobs

Human Resources Assistant Job Market in St. Louis

Who's Hiring

CRB
CRB5 open roles
Sonesta
Sonesta5 open roles
Stepful
Stepful5 open roles

Human Resources Assistant Jobs in St. Louis: Frequently Asked Questions

How do I get a human resources assistant job in St. Louis?

St. Louis hiring concentrates in healthcare networks, financial services companies, and large educational institutions in Clayton and the Central Business District, so targeting those employer types gives you a real edge. Candidates who have hands-on experience with HRIS software, onboarding coordination, or benefits administration stand out. Applying directly through employer career portals and building familiarity with Missouri-specific employment paperwork also moves your application forward faster in this market.

Which companies hire human resources assistants in St. Louis?

Companies currently hiring human resources assistants in St. Louis include CRB, Sonesta, and Stepful, per current listings on Migrate Mate as of August 2026. St. Louis draws a broad mix of large healthcare systems, regional banks, insurance companies, and manufacturing firms, all of which maintain active HR departments that hire at the assistant level on a rolling basis.

Are there remote human resources assistant jobs in St. Louis?

Yes, though remote availability is moderate since human resources assistant work often involves in-person onboarding, file management, and employee interactions that require an office presence. About 50% of human resources assistant openings tied to St. Louis are remote or hybrid as of August 2026, with hybrid schedules most common. Roles focused on data entry, HRIS administration, and benefits coordination tend to offer the most schedule flexibility in the St. Louis market.

How can I get a human resources assistant job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is through administrative or receptionist roles at healthcare systems or universities, which regularly promote internally into HR assistant positions. St. Louis employers such as large hospital networks and regional insurers also hire entry-level HR coordinators who complete onboarding support tasks before moving into full assistant duties. A working knowledge of Microsoft Office, attention to detail on employee records, and any coursework in business or HR management will help your application stand out locally.

See All 86 Human Resources Assistant Jobs in St. Louis

Find roles in St. Louis that match your experience and apply in just a few clicks.

Find Jobs