Medical Assistant Jobs in Columbia, SC
Medical Assistant jobs in Columbia, South Carolina are concentrated across the Midlands health corridor, with strong demand in Forest Acres, Harbison, and the downtown medical district. Employers like Prisma Health, Lexington Health, and Medical University of South Carolina fill steady openings in primary care, urgent care, and specialty clinics. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 47+ Medical Assistant jobs







LFP Forest Acres
Full Time
AM Shift
8 am - 5 pm
Sign-On Bonus: 3500
Lexington Health is a comprehensive network of care that includes six community medical and urgent care centers, nearly 80 physician practices, more than 9,000 health care professionals and Lexington Medical Center, a 607-bed teaching hospital in West Columbia, South Carolina. It was selected by Modern Healthcare as one of the Best Places to Work in Healthcare and was first in the state to achieve Magnet with Distinction status for excellence in nursing care. Consistently ranked as best in the Columbia Metro area by U.S. News & World Report, Lexington Health delivers more than 4,000 babies each year, performs more than 34,000 surgeries annually and is the region's third largest employer.
Lexington Health also includes an accredited Cancer Center of Excellence, the state’s first HeartCARE Center, the largest skilled nursing facility in the Carolinas, and an Alzheimer’s care center. Its postgraduate medical education programs include family medicine and transitional year residencies, as well as an informatics fellowship.
Job Summary
The Certified Medical Assistant (CMA) role may be either a Certified or Registered Medical Assistant (CMA/RMA) that is a member of the patient care team. They provide direct and indirect patient care under the direction of a Provider. Additionally, they provide patient support as directed for a variety of activities including, but not limited to, patient intake at office visit, documentation, vaccine and medication administration, clerical, environmental, and organizational tasks. Will Assist with appointment scheduling and maintaining medical record documentation in EPIC EHR system as required. Serves as a provider’s scribe as needed.
Minimum Qualifications
Minimum Education: High School Diploma or Equivalent, and sucessful completion of at least one of the following:
1. A medical assisting education program accredited by the Commission on Accreditation of Allied Health Education Programs or its successor, by the Accrediting Bureau of Health Education Schools or its successor, or by any accrediting agency recognized by the United States Department of Education, and which must include courses or components in anatomy and physiology, medical terminology, pharmacology, medical laboratory techniques, and clinical experience, provided the clinical experience component may be satisfied through an individual’s work experience with a health care employer;
2. A Career and Technical Education Health Sciences Program approved by the South Carolina Department of Education;
3. A medical assisting program provided by a branch of the United States military;
4. A medical assisting United States Department of Labor-approved Registered Apprenticeship program;
5. A training program that is delivered, in whole or in part, by a health care employer that aligns to a nationally accredited certification exam. (Must be complete by no later than 90 days after start date in role)
Minimum Years of Experience: None.
Substitutable Education & Experience: None.
Required Certifications/Licensure: Must currently hold and maintain an active certification or registry in Medical Assisting from a certifying body offering a certification program that is approved by the Board of Medical Examiners and the Board of Nursing and is accredited by the National Commission for Certifying Agencies or other accreditation body recognized by the Board of Medical Examiners and the Board of Nursing;
Current Basic Life Support certification (BLS) or must obtain within 90 days of hire date.
Required Training: The basic LMC competency assessment for CMAs must be successfully completed within the initial probationary period or any extension thereof.
Essential Functions
- Works in a cooperative manner that is consistent with LMC’s Service Expectations policy.
- Participates in activities related to patient care.
- Records patient data and observations relevant to patients needs and in accordance with credentials.
- Provides safety measures in accordance with office standards.
- Recognizes need for safety measures and takes appropriate action to prevent injury
- Demonstrates ability to provide a comfortable environment of care in accordance with office standards.
- Prepares patient for departure by reinforcing patient instructions and patient education
- Manages medications according to LMC policy, procedures and within scope of practice for credential.
- Enters pertinent information into Epic.
- Verifies that all information in the patient chart is correctly entered and associated; and initiates appropriate action when necessary (lab labels, lab requisition, visit summary, etc.).
- Schedules physician appointments, requests copies of the medical record (when indicated) and arrange for patient referral as requested.
- Demonstrates knowledge and effective use of medical terminology.
- Maintains established stock levels of clerical supplies.
- Restocks and /or orders supplies.
- Removes outdated forms or supplies.
Duties & Responsibilities
- Functions as a Clinical Scribe as needed: While functioning in the Scribe role the Clinical-Scribe must adhere to LMC’s policy and procedures for scribes.
- Abides by LMC’s Code of Conduct, accepts work assignments readily, and adheres to dress code and maintains personal hygiene and cleanliness appropriate to contact with patients, visitors and coworkers, supports and participates actively in change processes/performance improvement activities by willingly adopting new methods.
- Uses time and supplies/equipment in an efficient and effective manner.
- Demonstrates ability to coordinate multiple tasks.
- Completes assigned tasks within specified time frame.
- Prioritizes workload to best meet both patient and provider needs.
- Appropriately accounts for supplies and equipment.
- Restocks rooms with supplies needed for patient care.
- Identifies product needs and reports to the appropriate person.
- Assists in performing and documenting environmental checks as required by LMC policy and regulatory agencies.
- Willing to orient and train new employees as asked.
- Effectively uses electronic, verbal, non-verbal, written, and interpersonal communication skills in a clear and concise manner to ensure appropriate understanding and response and demonstrates open communication with co-workers.
- Maintains required certifications, completes yearly safety training and mandatory classes and clinical competencies assessments, and complies with annual employee health requirements.
- Performs all other duties as assigned.
We are committed to offering quality, cost-effective benefits choices for our employees and their families:
- Day ONE medical, dental and life insurance benefits
- Health care and dependent care flexible spending accounts (FSAs)
- Employees are eligible for enrollment into the 403(b) match plan day one. LHI matches dollar for dollar up to 6%.
- Employer paid life insurance – equal to 1x salary
- Employee may elect supplemental life insurance with low cost premiums up to 3x salary
- Adoption assistance
- LHI provides its full-time employees employer paid short-term disability and long-term disability coverage after 90 days of eligible employment
- Tuition reimbursement
- Student loan forgiveness
Equal Opportunity Employer
It is the policy of Lexington Health to provide equal opportunity of employment for all individuals, and to remain compliant with applicable state and federal laws and regulations. Lexington Health strives to provide a discrimination-free environment, and to recruit, select, on-board, and employ all employees without regard to race, color, religion, sex, age, disability, national origin, veteran status, or pregnancy, childbirth, or related medical conditions, including but not limited to, lactation. Lexington Health endeavors to upgrade and promote employees from within the hospital where possible and consistent with the employee’s desires and abilities and the hospital’s needs.
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Find Medical Assistant JobsMedical Assistant Job Market in Columbia
Who's Hiring
- Prisma Health19

- Lexington Health9

- Medical University of South Carolina6

- Prisma Health Urgent Care3P
- Doctors Care2
Top Industries Hiring
- Healthcare & Medical Services29
- Education1
Medical Assistant Jobs in Columbia: Frequently Asked Questions
How do I get a medical assistant job in Columbia?
Focus your search on Columbia's dense cluster of outpatient clinics, federally qualified health centers, and multi-specialty group practices anchored along the Midlands corridor and near the Palmetto Health and MUSC Health networks. Candidates with phlebotomy certification and electronic health record experience, especially Epic or NextGen, stand out most in this market. Applying directly through clinic system career portals, rather than waiting for listings to age, tends to move faster here.
Which companies hire medical assistants in Columbia?
Columbia medical assistant roles are posted by Prisma Health, Lexington Health, and Medical University of South Carolina and others right now, based on current listings on Migrate Mate as of July 2026. The Columbia market is anchored by large health system affiliates and independent specialty practices ranging from orthopedics to behavioral health.
Are there remote medical assistant jobs in Columbia?
Yes, though remote options are limited given that most medical assistant work is hands-on and clinic-based. About 0% of medical assistant openings tied to Columbia are remote or hybrid as of July 2026, covering roles such as prior authorization coordinators and telephonic care management. Those positions tend to sit within Columbia's larger health system administrative operations.
How can I get a medical assistant job in Columbia with little or no experience?
The most realistic entry path in Columbia is through externship-connected programs at Midlands Technical College, which feeds directly into local clinic hiring pipelines. Urgent care chains and federally qualified health centers in the Columbia area are notably more open to training new graduates than specialty practices. Highlighting a completed clinical rotation, even unpaid, and any patient-facing customer service experience gives entry-level candidates a concrete edge locally.
Which industries hire the most medical assistants in Columbia?
Columbia medical assistant roles concentrate in Healthcare & Medical Services and Education, based on current listings on Migrate Mate as of July 2026. Columbia's position as a state capital with a large insured government-employee population drives sustained demand across these sectors year-round.
Related Jobs in South Carolina
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