Medical Assistant Jobs in Greenville, SC
Medical assistant jobs in Greenville, South Carolina are in strong demand, concentrated in the Augusta Road corridor, Eastside, and the downtown medical district across primary care, urgent care, and specialty clinics. Employers hiring right now include Prisma Health, Bon Secours, and Advanced Dermatology and Cosmetic Surgery. See the openings below and apply to the ones that match your experience.
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Company Overview
Shriners Children’s is an organization that respects, supports, and values each other. Named as the 2025 best mid-sized employer by Forbes, we are engaged in providing excellence in patient care, embracing multi-disciplinary education, and research with global impact. We foster a learning environment that values evidenced based practice, experience, innovation, and critical thinking. Our compassion, integrity, accountability, and resilience define us as leaders in pediatric specialty care for our children and their families.
With 20+ hospitals, outpatient clinics, ambulatory care centers and outreach locations across the globe, we provide excellent care to children up to age 18 regardless of their family’s ability to pay or insurance status. Please click here to learn more about our locations.
Job Description
The Medical Assistant (MA) has responsibilities related to patient care in the outpatient clinic environment. The MA displays responsible behaviors, communicates effectively to others and functions as a member of the healthcare team. The MA must demonstrate competency in all skills related to the performance of patient care, including but not limited to obtaining heights, weights and vital signs in addition to gathering pertinent patient history and medication information. The MA maintains an inventory of examination/procedure room supplies, assists in the organization of efficient patient flow, and organizes the clinic environment to assure patient safety. Will be cross-trained in casting.
Key Responsibilities:
Assessment/Patient Care
Assists physicians, nursing and other health care professional with procedures, the intake and depart processes. Accurately documents findings during the intake process in the EMR.
Communication
Provides effective communication with patients and families that will enable safe and effective patient care.
Demonstrates knowledge and skills necessary to provide care appropriate to the age of the patient.
Communicates with family effectively regarding referrals to other sources.
Customer Service
Transfers and assists patients to examining rooms and other departments as necessary. Informs patients of any delays in care. Escorts patients to other services when needed.
Required Qualifications:
High School Diploma/GED
Certified Medical Assistant certification
Basic Life Support (BLS) (required within 30-90 days of hire)
Preferred Qualifications:
1 year pediatric/ambulatory care experience
EMR systems experience
RMA, CCMA, NCMA
Spanish proficiency
Familiarity with MS Office tools, HIPAA, infection control, patient safety protocols
Interest in casting
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Find Medical Assistant JobsMedical Assistant Job Market in Greenville
Who's Hiring
- Prisma Health18

- Bon Secours3

- Advanced Dermatology and Cosmetic Surgery2

- Tribe5131
- Elle OBGYN1

Top Industries Hiring
- Healthcare & Medical Services17
- Consulting & Professional Services1
Medical Assistant Jobs in Greenville: Frequently Asked Questions
How do I get a medical assistant job in Greenville?
Focus your search on Greenville's dense cluster of primary care practices, urgent care centers, and specialty clinics, particularly along Augusta Road, Woodruff Road, and the downtown Greenville Health System corridor. Candidates who hold a nationally recognized certification such as the CMA or RMA and have hands-on clinical experience in phlebotomy or EHR documentation move fastest here. Tailoring your application to multi-specialty group practices gives you a real edge in this market.
Which companies hire medical assistants in Greenville?
Employers hiring medical assistants in Greenville right now include Prisma Health, Bon Secours, and Advanced Dermatology and Cosmetic Surgery, based on current listings on Migrate Mate as of July 2026. Greenville's hiring is driven by a mix of large integrated health systems, independent specialty groups, and fast-growing urgent care chains that have expanded significantly across the metro in recent years.
Are there remote medical assistant jobs in Greenville?
Yes, though they are limited, since most medical assistant work is hands-on and clinic-based by nature. About 0% of medical assistant openings tied to Greenville are remote or hybrid as of July 2026, concentrated in roles focused on patient scheduling, insurance pre-authorization, and telehealth coordination rather than direct clinical care.
How can I get a medical assistant job in Greenville with little or no experience?
The most realistic entry path in Greenville is applying to urgent care chains and large multi-site group practices, which hire medical assistant trainees and externship graduates more consistently than smaller independent offices. Completing a practicum or clinical extern rotation at a Greenville-area site, even unpaid, makes a significant difference. Entry-level front-office or patient registration roles at local health systems also serve as a strong lateral move into clinical medical assisting.
Which industries hire the most medical assistants in Greenville?
The sectors hiring the most medical assistants in Greenville are Healthcare & Medical Services and Consulting & Professional Services, based on current listings on Migrate Mate as of July 2026. Greenville's continued growth as a regional healthcare hub, anchored by major health system expansions and a rising population in surrounding counties, keeps demand for medical assistants consistently high across these sectors.
Related Jobs in South Carolina
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