Oncology Specialist Jobs in Pennsylvania
Oncology Specialist jobs in Pennsylvania are consistently in demand, concentrated across major health systems, academic medical centers, and comprehensive cancer programs at every level from entry-level oncology coordinator through senior clinical specialist. Philadelphia, Pittsburgh, and the Lehigh Valley are the state's primary hiring hubs, where institutions like Penn Medicine, UPMC, and Geisinger Health have deep and ongoing oncology staffing needs. The most sought-after specialties in Pennsylvania include hematology-oncology, radiation oncology support, and oncology pharmacy. Find a role that fits below and apply directly.
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Territory: Keystone including Philadelphia and New Jersey.
Natera is seeking an experienced Clinical Oncology Specialist (COS) to join our specialized Genitourinary (GU) Oncology sales team. This high-impact, tumor-specific role will focus on driving adoption and growth of Signatera™, Natera's personalized, tumor-informed molecular residual disease (MRD) test, across the GU Oncology landscape.
Signatera is a circulating tumor DNA (ctDNA) assay designed to detect molecular residual disease and monitor disease recurrence. Across GU cancers, including bladder, renal cell carcinoma, and testicular cancers, Signatera provides highly specific molecular insights that can help clinicians assess recurrence risk, monitor disease status, and inform individualized patient management strategies.
The Clinical Oncology Specialist will serve as a strategic field partner and key representative of Natera Oncology, developing relationships with Key Opinion Leaders (KOLs) and healthcare providers across academic medical centers, integrated delivery networks, hospital systems, and select community oncology practices.
This position will have a primary focus on Urologic Oncology, with key call points including Urologic Oncologists, GU Surgical Oncologists, Radiation Oncologists, Medical Oncologists, Pathologists, and other healthcare providers involved in the diagnosis, treatment, and ongoing management of patients with genitourinary cancers.
Primary Responsibilities
- Develop and execute strategic territory business plans to drive Signatera adoption, achieve sales objectives, and maximize market opportunities.
- Build and strengthen relationships with Urologic Oncologists, GU Surgical Oncologists, Medical Oncologists, Radiation Oncologists, Pathologists, and other key stakeholders across the GU Oncology continuum of care.
- Drive new account acquisition, expand existing partnerships, and identify growth opportunities within academic medical centers, hospital systems, leading urology practices, and community oncology networks.
- Educate healthcare providers on Signatera's clinical applications, supporting evidence, and value in the management of GU cancers, including bladder, kidney, and testicular cancers.
- Develop relationships with Key Opinion Leaders (KOLs) specializing in GU Oncology, particularly within major academic medical centers and leading urology and oncology practices.
- Establish expertise in Natera's molecular diagnostics technology, clinical evidence, product offerings, and competitive landscape.
- Collaborate closely with Natera's Core Oncology Sales team and cross-functional partners to align account strategies and maximize commercial effectiveness.
- Identify opportunities to expand Signatera adoption through physician education, strategic account development, and multidisciplinary care team engagement.
- Navigate complex healthcare systems, reimbursement processes, and institutional requirements to support successful product adoption.
- Partner with internal teams to resolve operational challenges, support account needs, and ensure a positive customer experience.
- Collaborate with Medical Affairs to support appropriate scientific engagement and KOL development in accordance with company policies.
- Support the development of institutional care pathways, account-level workflows, and EMR integrations to facilitate testing adoption.
- Monitor market trends, competitive dynamics, and evolving clinical evidence in GU Oncology to identify opportunities for territory growth.
- Execute sales and marketing initiatives aligned with regional and national Oncology objectives.
Qualifications
- Bachelor's degree required.
- Minimum of 5 years of demonstrated sales success within Oncology, Urology, Urologic Oncology, Medical Devices, Molecular Diagnostics, Clinical Diagnostics, or the diagnostic laboratory industry.
- Experience calling on Urologic Oncologists, GU Surgical Oncologists, Urologists, or other GU Oncology specialists strongly preferred.
- Experience selling into academic medical centers, integrated healthcare systems, hospital networks, and/or community oncology practices preferred.
- Demonstrated track record of achieving or exceeding sales goals, developing new markets, and growing complex territories.
- Experience with molecular diagnostics, precision oncology, or innovative medical technologies preferred.
- Ability to travel 50–75%, including overnight travel as required.
Knowledge, Skills, and Abilities
- Strong understanding of the GU Oncology landscape, including key physician specialties, treatment pathways, and multidisciplinary care models.
- Knowledge of molecular diagnostics, ctDNA, MRD testing, and precision oncology preferred.
- Exceptional communication, presentation, relationship-building, and consultative selling skills.
- Strong business acumen with the ability to identify market opportunities, develop strategic account plans, and execute territory growth initiatives.
- Ability to establish and maintain trusted relationships with Key Opinion Leaders, physician stakeholders, and healthcare executives.
- Ability to effectively navigate complex healthcare systems, reimbursement environments, and institutional decision-making processes.
- Collaborative approach to working with cross-functional teams, including Core Oncology Sales, Marketing, Medical Affairs, and internal support functions.
- Strong organizational, analytical, and problem-solving skills.
- Self-motivated, results-oriented, and adaptable to a fast-paced, evolving healthcare environment.
- Commitment to ethical business practices, clinical integrity, and improving patient care.
Why Join Natera?
Join Natera and play a meaningful role in advancing precision oncology for patients with genitourinary cancers.
As a Clinical Oncology Specialist, you will have the opportunity to drive adoption of innovative MRD technology, establish relationships with leading Urologic Oncologists and cancer centers, and expand access to personalized molecular testing.
This is an opportunity to help shape the future of GU Oncology while contributing to Natera's continued growth and mission to transform disease management through innovative diagnostics.
Compensation & Benefits
The total on-target earnings (OTE) package includes:
- Competitive base salary with uncapped quarterly commissions.
- Car allowance program.
- Restricted Stock Units (RSUs).
- Comprehensive benefits package supporting health, wellness, and career growth.
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
- BBB announcement on job scams
- FBI Cyber Crime resource page
See All 7 Oncology Specialist Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Oncology Specialist JobsOncology Specialist Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Oncology Specialist Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Science & Research
What Pennsylvania Employers Look For
The qualifications that appear most often in oncology specialist jobs across Pennsylvania.
- Active Pennsylvania nursing or relevant clinical license recognized by the Pennsylvania State Board
- Experience in hematology-oncology, radiation oncology, or a related cancer care specialty
- Proficiency administering chemotherapy and managing oncology treatment protocols
- Familiarity with electronic health record systems used in oncology clinical environments
- Oncology Certified Nurse or equivalent credential preferred by most Pennsylvania employers
- Strong patient education and care coordination skills within multidisciplinary oncology teams
Oncology Specialist Jobs in Pennsylvania: Frequently Asked Questions
How do you become a oncology specialist in Pennsylvania?
Becoming an oncology specialist in Pennsylvania starts with earning a nursing degree or relevant clinical credential, then passing the NCLEX-RN to obtain licensure through the Pennsylvania State Board of Nursing. From there, gaining experience in oncology settings and pursuing the Oncology Certified Nurse credential through the Oncology Nursing Certification Corporation strengthens your candidacy. Many Pennsylvania health systems also offer dedicated oncology orientation programs for newly licensed clinicians entering this specialty.
How much do oncology specialists make in Pennsylvania?
Oncology specialists in Pennsylvania earn a median of about $103,150 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $70,570 for the lowest 10% to over $139,760 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire oncology specialists in Pennsylvania?
Employers hiring oncology specialists in Pennsylvania right now include Natera, UPMC, and Tower Health, based on current listings on Migrate Mate as of October 2026. Pennsylvania's dense concentration of academic medical centers and regional cancer networks means oncology roles appear across both large urban health systems and community hospital programs throughout the state.
Which Pennsylvania cities have the most oncology specialist jobs?
Philadelphia, Pennsylvania, and Sayre have the most oncology specialist openings in Pennsylvania. Philadelphia leads because of its dense cluster of academic medical centers and National Cancer Institute-designated programs, while Pittsburgh's activity is driven by UPMC's expansive oncology network, and smaller markets like Allentown and Hershey reflect the regional cancer program investments made by Lehigh Valley Health Network and Penn State Health.
Are there remote oncology specialist jobs in Pennsylvania?
Yes, but they're rare. About 75% of oncology specialist openings tied to Pennsylvania are remote or hybrid as of October 2026, reflecting the hands-on clinical nature of most roles in this field. The parts of the work most likely to be remote or hybrid include oncology care coordination, patient navigation, prior authorization, and telehealth-based follow-up consultations rather than direct treatment or infusion roles.
How can I get hired as a oncology specialist in Pennsylvania with little or no experience?
The most realistic entry path is applying to oncology residency or new-graduate orientation programs run by large Pennsylvania systems like Penn Medicine, UPMC, or Jefferson Health, which recruit nurses without specialty experience and provide structured oncology training. Transferring from a closely related role in medical-surgical nursing, hematology, or infusion therapy is a common bridge. Completing the Oncology Nursing Society's foundational courses and holding a current Pennsylvania nursing license give a candidate a meaningful edge over the competition.
Where can I find and apply to oncology specialist jobs in Pennsylvania?
You can find and apply to oncology specialist jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings from employers actively hiring in the state. Find roles that fit your experience and specialty and apply directly to the employer. No profile creation or sign-up is required to view and apply to the listings available.
See All 7 Oncology Specialist Jobs in Pennsylvania
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