Operations Director Jobs in San Francisco, CA

Operations Director jobs in San Francisco are concentrated in SoMa, the Financial District, and Mission Bay, driven by demand in technology, healthtech, and financial services. Employers hiring right now include Genentech, CRUSOE, and Ripple. Find a role that fits below and apply directly.

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Overview

Open roles494+
Top employerGenentech
Work type45% On-site
Top credentialMaster's degree in business administration
Companies hiring50

Showing 5 of 494+ Operations Director jobs

City and County of San Francisco
Chief Operating Officer
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City and County of San Francisco
Added 2d ago
Chief Operating Officer
City and County of San Francisco
San Francisco, California
Executive Leadership & C-Suite
Project & Program Management
Human Resources
Business Operations
Compliance & Legal
Project Management
$201k - $256k/yr
On-Site
Bachelor's

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IQVIA
Sr. Strategic Operations Director
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IQVIA
Added 2d ago
Sr. Strategic Operations Director
IQVIA
San Francisco, California
Business Operations
Program Management
Project Management
$123k - $344k/yr
Remote (US)
10,000+

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City and County of San Francisco
Chief Operating Officer (0953 - Deputy Director III) - San Francisco Public Library
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City and County of San Francisco
Added 2d ago
Chief Operating Officer (0953 - Deputy Director III) - San Francisco Public Library
City and County of San Francisco
San Francisco, California
Business Operations
Executive Leadership & C-Suite
Project Management
$201k - $256k/yr
Bachelor's degree in social work
5,001-10,000

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Genentech
Senior Director, Business Operations & Portfolio Controls
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Genentech
Added 5d ago
Senior Director, Business Operations & Portfolio Controls
Genentech
San Francisco, California
Content & Communications
Creative & Design
Marketing
$189k - $352k/yr
Bachelor's degree in construction management
10,000+

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gate group
Director Culinary Operations
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gate group
Added 5d ago
Director Culinary Operations
gate group
San Francisco, California
Business Development
Customer Success
Program Management
Project Management
$150k - $160k/yr
Bachelor's degree in industrial engineering

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See All 494+ Operations Director Jobs in San Francisco

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Operations Director Job Market in San Francisco

Who's Hiring

  • Genentech
    Genentech33
  • CRUSOE
    CRUSOE17
  • Ripple
    Ripple17
  • DoorDash
    DoorDash17
  • Gap
    Gap17

Top Industries Hiring

  • Technology & Software50
  • Banking & Financial Services33
  • Retail17
  • Consulting & Professional Services17
  • Medical Devices8

Operations Director Jobs in San Francisco: Frequently Asked Questions

How do I get a operations director job in San Francisco?

The strongest path into an operations director role in San Francisco runs through technology companies, healthtech firms, and financial services employers, all of which concentrate hiring in SoMa, Mission Bay, and the Financial District. Candidates who stand out here typically combine cross-functional leadership experience with familiarity with high-growth or regulated environments. Demonstrating comfort with rapid scaling, vendor management, and data-driven process improvement gives applicants a clear edge in this market.

Which companies hire operations directors in San Francisco?

Companies currently hiring operations directors in San Francisco include Genentech, CRUSOE, and Ripple, per current listings on Migrate Mate as of August 2026. San Francisco's employer mix skews heavily toward venture-backed technology companies, established fintech firms, and large hospital and healthtech systems, all of which maintain active operations leadership hiring throughout the year.

Are there remote operations director jobs in San Francisco?

Yes, though remote availability depends heavily on the role: operations directors overseeing physical sites, logistics, or in-person teams typically need to be on-site, while those focused on process, analytics, or vendor operations can work remotely more often. About 55% of operations director openings tied to San Francisco are remote or hybrid as of August 2026, with the highest remote share found in software and fintech companies based in SoMa and the Financial District.

How can I get a operations director job in San Francisco with little or no experience?

The most realistic entry path is moving up from an operations manager or senior operations associate role within a San Francisco technology startup or healthtech company, where lean teams create faster promotion cycles. Employers in Mission Bay's life sciences cluster and SoMa's startup corridor regularly hire operations coordinators and analysts who can grow into director-level positions. Building experience with tools like Salesforce, NetSuite, or project management platforms common in San Francisco's tech sector strengthens a candidate's profile considerably.

Which industries hire the most operations directors in San Francisco?

Most operations director openings in San Francisco sit in Technology & Software, Banking & Financial Services, and Retail, per current listings on Migrate Mate as of August 2026. San Francisco's concentration of enterprise technology companies, venture-funded startups, and Mission Bay's growing life sciences and healthtech campus drives consistent demand for operations leadership across all three sectors.

See All 494+ Operations Director Jobs in San Francisco

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