Operations Director Jobs in San Francisco, CA
Operations Director jobs in San Francisco are concentrated in SoMa, the Financial District, and Mission Bay, driven by demand in technology, healthtech, and financial services. Employers hiring right now include DoorDash, Airwallex, and OpenAI. Find a role that fits below and apply directly.
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Showing 5 of 271+ Operations Director jobs
The Position
Who we are:
Public Affairs & Access (PAA) is a multi-disciplinary organization that includes Corporate Communications; Policy, Evidence & Access Strategy; Channel & Contract Management; External Affairs; Access Solutions and Patient Support; and Strategy and Business Operations. Our purpose is to deliver impact through a fully integrated public affairs function that leverages our capabilities and world-class Genentech brand to deliver on our mission for patients and our employees.
The Strategy and Business Operations team is accountable for maximizing the impact of PAA through strategic operations partnership focused on delivering business priorities and outcomes.
The Opportunity
We are seeking a Director, Strategy and Business Operations to support our Patient Experience (PX) organization within Public Affairs & Access (PAA). In this high-impact role, you will serve as the Operations Lead (Chief of Staff) to the Vice President of PX and their leadership team. You will be responsible for defining the function's operational strategy, driving strategic and financial planning, and leading a dedicated team of operations professionals to maximize business outcomes.
- Strategic Operations Leadership: Lead and oversee the PX operations team, setting the strategic vision, managing performance, and fostering a culture of belonging, innovation, and collaboration.
- Chief of Staff Partnership: Serve as the primary strategic thought partner to the VP of PX and senior leadership, translating high-level vision into actionable operational plans and managing the "organizational heartbeat" of leadership meetings.
- Business & Financial Stewardship: Develop and facilitate fit-for-purpose business, resource, and financial planning frameworks, including budget management, headcount planning, and outside spend optimization.
- Change Management & Planning: Lead strategic planning, corporate implementation, and complex change management activities for cross-functional teams, workstreams, and steering committees.
- People & Talent Management: Drive people practices within the function, including talent attraction and retention, year-end performance reviews, talent management, succession planning, and individual career development.
- Communications & Engagement: Develop and execute multi-channel communication and engagement strategies to drive collaboration and alignment within PX and across the broader Genentech enterprise.
Who you are
- You have a Bachelor’s degree.
- You have 8 or more years of relevant experience, specifically in operations, management consulting, or strategy and operations.
- Experience serving as an Operations Lead / Chief of Staff (or similar capacity) is required.
- You have 2 or more years of people management experience.
- You are an expert project manager and agile facilitator with a proven track record of leading large change management projects and implementing "new ways of working."
- Expert level project management skills. Proven track record at leading large change management projects, including project management, policy development, communication/training planning, and vendor management.
- Expert knowledge (or a demonstrated aptitude to learn) healthcare compliance.
Preferred Qualifications
- Project Management Certification (PMI, PMP, etc.) is highly desirable.
- 5 or more years of experience managing operations to support patient support or market access activities.
- Prior experience managing vendors and contractors.
- Deep expertise in the U.S. patient access and payer landscape, including commercial, government, and specialty pharmacy channels.
Location:
- This position is based in South San Francisco, CA at our Genentech Campus.
- Relocation benefits are NOT offered on this posting.
The expected salary range for this position based on the primary location at South San Francisco, CA is $166,500/yr to $309,100/yr. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
JOB FACTS
- Job Sub Category: Operations
- Schedule: Full time
- Job Type: Regular
- Posted Date: Jun 25th 2026
- Job ID: 202606-115226
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
The Position
Who we are:
Public Affairs & Access (PAA) is a multi-disciplinary organization that includes Corporate Communications; Policy, Evidence & Access Strategy; Channel & Contract Management; External Affairs; Access Solutions and Patient Support; and Strategy and Business Operations. Our purpose is to deliver impact through a fully integrated public affairs function that leverages our capabilities and world-class Genentech brand to deliver on our mission for patients and our employees.
The Strategy and Business Operations team is accountable for maximizing the impact of PAA through strategic operations partnership focused on delivering business priorities and outcomes.
The Opportunity
We are seeking a Director, Strategy and Business Operations to support our Patient Experience (PX) organization within Public Affairs & Access (PAA). In this high-impact role, you will serve as the Operations Lead (Chief of Staff) to the Vice President of PX and their leadership team. You will be responsible for defining the function's operational strategy, driving strategic and financial planning, and leading a dedicated team of operations professionals to maximize business outcomes.
- Strategic Operations Leadership: Lead and oversee the PX operations team, setting the strategic vision, managing performance, and fostering a culture of belonging, innovation, and collaboration.
- Chief of Staff Partnership: Serve as the primary strategic thought partner to the VP of PX and senior leadership, translating high-level vision into actionable operational plans and managing the "organizational heartbeat" of leadership meetings.
- Business & Financial Stewardship: Develop and facilitate fit-for-purpose business, resource, and financial planning frameworks, including budget management, headcount planning, and outside spend optimization.
- Change Management & Planning: Lead strategic planning, corporate implementation, and complex change management activities for cross-functional teams, workstreams, and steering committees.
- People & Talent Management: Drive people practices within the function, including talent attraction and retention, year-end performance reviews, talent management, succession planning, and individual career development.
- Communications & Engagement: Develop and execute multi-channel communication and engagement strategies to drive collaboration and alignment within PX and across the broader Genentech enterprise.
Who you are
- You have a Bachelor’s degree.
- You have 8 or more years of relevant experience, specifically in operations, management consulting, or strategy and operations.
- Experience serving as an Operations Lead / Chief of Staff (or similar capacity) is required.
- You have 2 or more years of people management experience.
- You are an expert project manager and agile facilitator with a proven track record of leading large change management projects and implementing "new ways of working."
- Expert level project management skills. Proven track record at leading large change management projects, including project management, policy development, communication/training planning, and vendor management.
- Expert knowledge (or a demonstrated aptitude to learn) healthcare compliance.
Preferred Qualifications
- Project Management Certification (PMI, PMP, etc.) is highly desirable.
- 5 or more years of experience managing operations to support patient support or market access activities.
- Prior experience managing vendors and contractors.
- Deep expertise in the U.S. patient access and payer landscape, including commercial, government, and specialty pharmacy channels.
Location:
- This position is based in South San Francisco, CA at our Genentech Campus.
- Relocation benefits are NOT offered on this posting.
The expected salary range for this position based on the primary location at South San Francisco, CA is $166,500/yr to $309,100/yr. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
JOB FACTS
- Job Sub Category: Operations
- Schedule: Full time
- Job Type: Regular
- Posted Date: Jun 25th 2026
- Job ID: 202606-115226
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
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Find Operations Director JobsOperations Director Job Market in San Francisco
Who's Hiring
- DoorDash11
- Airwallex11
- OpenAI8
- Amazon8
- Lyft6
Top Industries Hiring
- Technology & Software129
- Banking & Financial Services20
- Retail18
- Healthcare & Medical Services11
- Science & Research10
Operations Director Jobs in San Francisco: Frequently Asked Questions
How do I get a operations director job in San Francisco?
The strongest path into an operations director role in San Francisco runs through technology companies, healthtech firms, and financial services employers, all of which concentrate hiring in SoMa, Mission Bay, and the Financial District. Candidates who stand out here typically combine cross-functional leadership experience with familiarity with high-growth or regulated environments. Demonstrating comfort with rapid scaling, vendor management, and data-driven process improvement gives applicants a clear edge in this market.
Which companies hire operations directors in San Francisco?
Companies currently hiring operations directors in San Francisco include DoorDash, Airwallex, and OpenAI, per current listings on Migrate Mate as of June 2026. San Francisco's employer mix skews heavily toward venture-backed technology companies, established fintech firms, and large hospital and healthtech systems, all of which maintain active operations leadership hiring throughout the year.
Are there remote operations director jobs in San Francisco?
Yes, though remote availability depends heavily on the role: operations directors overseeing physical sites, logistics, or in-person teams typically need to be on-site, while those focused on process, analytics, or vendor operations can work remotely more often. About 35% of operations director openings tied to San Francisco are remote or hybrid as of June 2026, with the highest remote share found in software and fintech companies based in SoMa and the Financial District.
How can I get a operations director job in San Francisco with little or no experience?
The most realistic entry path is moving up from an operations manager or senior operations associate role within a San Francisco technology startup or healthtech company, where lean teams create faster promotion cycles. Employers in Mission Bay's life sciences cluster and SoMa's startup corridor regularly hire operations coordinators and analysts who can grow into director-level positions. Building experience with tools like Salesforce, NetSuite, or project management platforms common in San Francisco's tech sector strengthens a candidate's profile considerably.
Which industries hire the most operations directors in San Francisco?
Most operations director openings in San Francisco sit in Technology & Software, Banking & Financial Services, and Retail, per current listings on Migrate Mate as of June 2026. San Francisco's concentration of enterprise technology companies, venture-funded startups, and Mission Bay's growing life sciences and healthtech campus drives consistent demand for operations leadership across all three sectors.
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