Operations Jobs in Durham, NC

Operations jobs in Durham, North Carolina are in strong demand across life sciences, research, and healthcare, concentrated in the Research Triangle Park corridor, Downtown Durham, and the Chesterfield district. Employers hiring right now include Duke Health, City of Durham, NC, and Merck. See the openings below and apply to the ones that match your experience.

Find Operations Jobs

Overview

Open roles86
Top employerDuke Health
Work type60% On-site
Top credentialHigh school diploma or GED
Companies hiring71

Showing 5 of 86+ Operations jobs

Hewlett Packard Enterprise | HPE
Director, Business Operations - CloudOps Software & Platform
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Hewlett Packard Enterprise | HPE
Added 1d ago
Director, Business Operations - CloudOps Software & Platform
Hewlett Packard Enterprise | HPE
Durham, North Carolina
Clinical Support
Healthcare Administration
Medical Specialists
$151k - $302k/yr
Master's degree in business administration
10,000+

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Appian
Lead Sales Operations Analyst
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Appian
Added 1d ago
Lead Sales Operations Analyst
Appian
Durham, North Carolina
Business Operations
Business Analysis
Sales
Business Analyst
Revenue Operations & Enablement
$100k - $200k/yr
On-Site
Bachelor's
1,001-5,000

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I
Domestic Operations Lead - NC
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I
Added 1d ago
Domestic Operations Lead - NC
Ivy Camps USA
Durham, North Carolina
Human Resources (HR) — Generalist
Learning & Development
Recruiting & Talent Acquisition
Hybrid
Bachelor's degree

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Merck
Associate Technician Operations Night Shift
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Merck
Added 1d ago
Associate Technician Operations Night Shift
Merck
Durham, North Carolina
Automation QA
Maintenance & Repair
Manufacturing Operations
Quality Control
$43k - $68k/yr
High school diploma or GED
10,000+

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Republic Finance
Branch Operations Intern
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Republic Finance
Added 2d ago
Branch Operations Intern
Republic Finance
Durham, North Carolina
Business Development
Customer Success
Program Management
Project Management
1,001-5,000

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See All 86 Operations Jobs in Durham

Find roles in Durham that match your experience and apply in just a few clicks.

Find Operations Jobs

Operations Job Market in Durham

Who's Hiring

Duke Health
Duke Health5 open roles
City of Durham, NC
City of Durham, NC4 open roles
Merck
Merck3 open roles

Top Industries Hiring

  • Consulting & Professional Services
  • Renewable Energy
  • Technology & Software
  • Biotechnology & Pharmaceuticals
  • Energy

Operations Jobs in Durham: Frequently Asked Questions

How do I get a operations job in Durham?

Focus your search on Durham's dominant sectors: life sciences, university research operations, healthcare systems, and technology firms anchored near Research Triangle Park. Employers in these industries consistently hire for supply chain, facilities, and process improvement roles. Candidates who can demonstrate cross-functional coordination experience, familiarity with regulated environments such as pharma or clinical settings, and strong data literacy tend to stand out in this market.

Which companies hire operationss in Durham?

Durham operations roles are posted by Duke Health, City of Durham, NC, and Merck and others right now, based on current listings on Migrate Mate as of July 2026. Durham's employer mix skews toward large research institutions, biotech firms, and academic medical centers, alongside a growing number of technology and logistics companies that have expanded into the area.

Are there remote operations jobs in Durham?

Yes, though it depends heavily on the role: analytical, planning, and coordination functions often support remote or hybrid arrangements, while facilities, warehouse, and on-site production roles typically require a physical presence. About 40% of operations openings tied to Durham are remote or hybrid as of July 2026. Process improvement and project operations positions at Durham's tech and life sciences companies are the most likely to offer flexible location options.

How can I get a operations job in Durham with little or no experience?

The most realistic entry path in Durham is through operations coordinator or administrative operations roles at Duke University, Duke Health, or the research institutions clustered around Research Triangle Park, which regularly hire candidates without extensive prior experience. Lateral moves from customer service, logistics coordination, or lab support roles are common. Candidates who highlight scheduling, vendor communication, or inventory management experience, even from part-time or internship work, gain a concrete edge with Durham employers.

Which industries hire the most operationss in Durham?

Durham operations roles concentrate in Consulting & Professional Services, Renewable Energy, and Technology & Software, based on current listings on Migrate Mate as of July 2026. Durham's identity as a hub for university research, pharmaceutical development, and healthcare delivery makes those sectors the steadiest sources of local operations hiring year over year.

See All 86 Operations Jobs in Durham

Find roles in Durham that match your experience and apply in just a few clicks.

Find Operations Jobs