Principal Jobs in Indianapolis, IN
Principal jobs in Indianapolis are in strong demand, concentrated in the Meridian-Kessler corridor, Downtown, and the North Meridian Street education and nonprofit belt, with openings across K-12 education, healthcare administration, and professional services. Employers actively hiring include Eli Lilly, V2X, and Cardinal Health. Scan the live roles below and apply to whichever ones fit.
Find Principal JobsOverview
Open roles59
Top employerEli Lilly
Work type70% On-site
Top credentialBachelor's degree in engineering
Companies hiring30
Showing 5 of 59+ Principal jobs
Principal Systems Engineer
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New 1m ago
V2X
Principal Systems Engineer
Indianapolis, Indiana
New 1m ago
Sr. Principal Systems Engineer
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New 1m ago
V2X
Sr. Principal Systems Engineer
Indianapolis, Indiana
New 1m ago
Principal Mechanical Engineer
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New 1m ago
V2X
Principal Mechanical Engineer
Indianapolis, Indiana
New 1m ago
Principal Sales Rep - CAS | IN
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New 1m ago
Medtronic
Principal Sales Rep - CAS | IN
Indianapolis, Indiana
New 1m ago
Sr. Principal Security Engineer, Application Security Strategy & Architecture
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New 1m ago
Eli Lilly
Sr. Principal Security Engineer, Application Security Strategy & Architecture
Indianapolis, Indiana
New 1m ago
New 1m ago
Principal Systems Engineer
V2X·Indianapolis, Indiana
Job functions:
On-Site
Bachelor's degree in engineering
10,000+ employees
Job Description
Overview:
Desired Skills:
At V2X, we are deeply committed to both equal employment opportunity, including protection for Veterans and individuals with disabilities, and fostering an inclusive and diverse workplace. We ensure all individuals are treated with fairness, respect, and dignity, recognizing the strength that comes from a workforce rich in diverse experiences, perspectives, and skills. This commitment, aligned with our core Vision and Values of Integrity, Respect, and Responsibility, allows us to leverage differences, encourage innovation, and expand our success in the global marketplace, ultimately enabling us to best serve our clients
Working across the globe, V2X builds smart solutions designed to integrate physical and digital infrastructure from base to battlefield. We bring 120 years of successful mission support to improve security, streamline logistics, and enhance readiness. Aligned around a shared purpose, our $3.9B company and 16,000 people work alongside our clients, here and abroad, to tackle their most complex challenges with integrity, respect, responsibility, and professionalism.
V2X is seeking a Principal Systems Engineer to join our Engineering team in Indianapolis, IN supporting development and integration of advanced systems including situational awareness displays, mission computers, avionics, sensors, mission equipment, and radar systems. Our Indianapolis facility also supports a variety of other product lines serving multiple Department of Defense (DoD) customers providing the opportunity to work on a diverse set of programs and roles supporting the continued advancement of your career.
Responsibilities:
The Principal Systems Engineer will support the Chief Engineer and Program Manager in all aspects of product area execution and customer interface. The position requires in-depth technical domain knowledge, strong communication skills, and ability to build close customer relationships. The Principal Systems Engineer will be part of the leadership team that represents the company to the customer and upper leadership. The Principal Systems Engineer is also responsible to provide technical and programmatic guidance throughout the entire lifecycle to a multi-domain development team, including proactively driving resolutions of issues encountered. The Principal Systems Engineer also provides program support throughout the development life cycle, from concept development, requirements definition, functional analysis, design review support, system implementation, integration, verification, and validation.
The ideal candidate embraces modern development processes and techniques that improve product quality & team productivity. We are looking for engineers that enjoy a challenge and have a passion to support our DoD customers and international allies.
Qualifications:
Required Skills:
- Must be a U.S. Citizen with the ability to obtain a Secret Clearance.
- Minimum 12 years of related engineering experience in systems, software, or hardware engineering.
- Experience providing leadership, technical direction, and guidance to multi-discipline teams.
- Ability to take ownership of the engineering scope within the program and drive the necessary tasks to ultimately ensure the cross-function team meets the technical requirements.
- Experience leading the development, integration and test of military avionics systems or similarly complex systems.
- Experience leading requirements development, hardware and software integration, and requirements verification.
- Experience with development, integration, and test of complex systems onto air, sea, and/or ground platforms.
- Experience with design, integration, and certification of embedded hardware and software subsystems, transitioning products from development to production, and obsolescence management.
- Experience developing technical baselines (requirements/architecture); leading development teams; and developing and reviewing Engineering Change Requests.
- Experience leading technical Analysis of Alternatives (AoA) and/or Trade Studies, performing Risk and Opportunity analyses, and tracking and mitigating risks.
- Strong communication skills and ability to effectively communicate to internal and external stakeholders including leading both internal and customer design reviews.
- Experience creating Trade Studies and analyzing technical data.
- Project management experience including cost, schedule, supplier management, risk, and opportunity assessment.
- In-depth understanding of the System Engineering Lifecycle and processes.
- Experience mentoring engineers of all grade levels.
- Must have a valid U.S. Passport.
- Ability to travel up to 25% of the time.
Desired Skills:
- Previous experience as a Lead Systems Engineer, Integrated Product Team Lead, and/or Product Owner.
- Experience working the front end of the business, creating/reviewing RFPs, SOWs, BOEs, technical volumes, proposals, cost, and schedule estimates.
- Experience managing suppliers and overseeing the development of subsystems and components.
- Experience with Model Based Systems Engineering (MBSE) methods, tools, and languages.
- Experience working with government customers including the US Army, US Navy, USMC, and/or USAF.
- Experience implementing performance requirements (i.e. -ilities) such as Reliability, Testability, Maintainability, Producibility, and System/Software Safety.
- Knowledge and experience working with digital data standards such as: MIL-STD-1553, MIL-STD-1760, Universal Armament Interface (UAI), Radio Frequency (RF) communication, and ENET protocols.
- Current Active DoD Secret or higher Clearance.
Education / Certifications:
- Bachelor’s Degree in Engineering or related STEM discipline.
At V2X, we are deeply committed to both equal employment opportunity, including protection for Veterans and individuals with disabilities, and fostering an inclusive and diverse workplace. We ensure all individuals are treated with fairness, respect, and dignity, recognizing the strength that comes from a workforce rich in diverse experiences, perspectives, and skills. This commitment, aligned with our core Vision and Values of Integrity, Respect, and Responsibility, allows us to leverage differences, encourage innovation, and expand our success in the global marketplace, ultimately enabling us to best serve our clients
#LI-WH1
#Clearance
#Clearance
V2X
Principal Systems Engineer
Indianapolis, Indiana
New 1m ago10,000+ employees
Job functions:
On-Site
Bachelor's degree in engineering
Job Description
Overview:
Desired Skills:
At V2X, we are deeply committed to both equal employment opportunity, including protection for Veterans and individuals with disabilities, and fostering an inclusive and diverse workplace. We ensure all individuals are treated with fairness, respect, and dignity, recognizing the strength that comes from a workforce rich in diverse experiences, perspectives, and skills. This commitment, aligned with our core Vision and Values of Integrity, Respect, and Responsibility, allows us to leverage differences, encourage innovation, and expand our success in the global marketplace, ultimately enabling us to best serve our clients
Working across the globe, V2X builds smart solutions designed to integrate physical and digital infrastructure from base to battlefield. We bring 120 years of successful mission support to improve security, streamline logistics, and enhance readiness. Aligned around a shared purpose, our $3.9B company and 16,000 people work alongside our clients, here and abroad, to tackle their most complex challenges with integrity, respect, responsibility, and professionalism.
V2X is seeking a Principal Systems Engineer to join our Engineering team in Indianapolis, IN supporting development and integration of advanced systems including situational awareness displays, mission computers, avionics, sensors, mission equipment, and radar systems. Our Indianapolis facility also supports a variety of other product lines serving multiple Department of Defense (DoD) customers providing the opportunity to work on a diverse set of programs and roles supporting the continued advancement of your career.
Responsibilities:
The Principal Systems Engineer will support the Chief Engineer and Program Manager in all aspects of product area execution and customer interface. The position requires in-depth technical domain knowledge, strong communication skills, and ability to build close customer relationships. The Principal Systems Engineer will be part of the leadership team that represents the company to the customer and upper leadership. The Principal Systems Engineer is also responsible to provide technical and programmatic guidance throughout the entire lifecycle to a multi-domain development team, including proactively driving resolutions of issues encountered. The Principal Systems Engineer also provides program support throughout the development life cycle, from concept development, requirements definition, functional analysis, design review support, system implementation, integration, verification, and validation.
The ideal candidate embraces modern development processes and techniques that improve product quality & team productivity. We are looking for engineers that enjoy a challenge and have a passion to support our DoD customers and international allies.
Qualifications:
Required Skills:
- Must be a U.S. Citizen with the ability to obtain a Secret Clearance.
- Minimum 12 years of related engineering experience in systems, software, or hardware engineering.
- Experience providing leadership, technical direction, and guidance to multi-discipline teams.
- Ability to take ownership of the engineering scope within the program and drive the necessary tasks to ultimately ensure the cross-function team meets the technical requirements.
- Experience leading the development, integration and test of military avionics systems or similarly complex systems.
- Experience leading requirements development, hardware and software integration, and requirements verification.
- Experience with development, integration, and test of complex systems onto air, sea, and/or ground platforms.
- Experience with design, integration, and certification of embedded hardware and software subsystems, transitioning products from development to production, and obsolescence management.
- Experience developing technical baselines (requirements/architecture); leading development teams; and developing and reviewing Engineering Change Requests.
- Experience leading technical Analysis of Alternatives (AoA) and/or Trade Studies, performing Risk and Opportunity analyses, and tracking and mitigating risks.
- Strong communication skills and ability to effectively communicate to internal and external stakeholders including leading both internal and customer design reviews.
- Experience creating Trade Studies and analyzing technical data.
- Project management experience including cost, schedule, supplier management, risk, and opportunity assessment.
- In-depth understanding of the System Engineering Lifecycle and processes.
- Experience mentoring engineers of all grade levels.
- Must have a valid U.S. Passport.
- Ability to travel up to 25% of the time.
Desired Skills:
- Previous experience as a Lead Systems Engineer, Integrated Product Team Lead, and/or Product Owner.
- Experience working the front end of the business, creating/reviewing RFPs, SOWs, BOEs, technical volumes, proposals, cost, and schedule estimates.
- Experience managing suppliers and overseeing the development of subsystems and components.
- Experience with Model Based Systems Engineering (MBSE) methods, tools, and languages.
- Experience working with government customers including the US Army, US Navy, USMC, and/or USAF.
- Experience implementing performance requirements (i.e. -ilities) such as Reliability, Testability, Maintainability, Producibility, and System/Software Safety.
- Knowledge and experience working with digital data standards such as: MIL-STD-1553, MIL-STD-1760, Universal Armament Interface (UAI), Radio Frequency (RF) communication, and ENET protocols.
- Current Active DoD Secret or higher Clearance.
Education / Certifications:
- Bachelor’s Degree in Engineering or related STEM discipline.
At V2X, we are deeply committed to both equal employment opportunity, including protection for Veterans and individuals with disabilities, and fostering an inclusive and diverse workplace. We ensure all individuals are treated with fairness, respect, and dignity, recognizing the strength that comes from a workforce rich in diverse experiences, perspectives, and skills. This commitment, aligned with our core Vision and Values of Integrity, Respect, and Responsibility, allows us to leverage differences, encourage innovation, and expand our success in the global marketplace, ultimately enabling us to best serve our clients
#LI-WH1
#Clearance
#Clearance
See All 59 Principal Jobs in Indianapolis
Find roles in Indianapolis that match your experience and apply in just a few clicks.
Find Principal JobsPrincipal Job Market in Indianapolis
Who's Hiring
- Eli Lilly15
- V2X7
- Cardinal Health5
- Elanco2
- Paramount Schools of Excellence2P
Top Industries Hiring
- Biotechnology & Pharmaceuticals16
- Consulting & Professional Services5
- Aerospace & Defense4
- Distribution & Wholesale3
- Manufacturing2
Principal Jobs in Indianapolis: Frequently Asked Questions
How do I get a principal job in Indianapolis?
Indianapolis principals are hired most actively through Indianapolis Public Schools, the growing network of charter operators concentrated on the east and near-north sides, and the Catholic schools under the Archdiocese of Indianapolis. Candidates who stand out have already logged assistant principal or department chair experience within Indiana schools. Networking through the Indiana Association of School Principals and attending IPS community meetings gives local applicants a concrete edge over out-of-state candidates.
Which companies hire principals in Indianapolis?
Companies currently hiring principals in Indianapolis include Eli Lilly, V2X, and Cardinal Health, per current listings on Migrate Mate as of July 2026. Indianapolis draws a mix of large public school districts, charter management organizations, and private healthcare and professional-services firms that all use the principal title across leadership and technical tracks.
Are there remote principal jobs in Indianapolis?
Yes, though availability depends heavily on the role type: instructional and campus-based principal positions are almost always on-site, while principal-level roles in software engineering, product, or consulting can be fully remote. About 30% of principal openings tied to Indianapolis are remote or hybrid as of July 2026. Tech and professional-services employers headquartered Downtown or in Keystone Crossing tend to offer the most flexibility.
How can I get a principal job in Indianapolis with little or no experience?
The most realistic entry path in Indianapolis is moving through an assistant principal or instructional coach role within IPS or a local charter network, which provides direct exposure to the leadership responsibilities hiring committees evaluate. Entry-level candidates in non-education sectors can target Indianapolis-based consulting and healthcare firms that hire associate or junior principal roles as a defined step on their internal career ladders, using project work as proof of readiness.
Which industries hire the most principals in Indianapolis?
Most principal openings in Indianapolis sit in Biotechnology & Pharmaceuticals, Consulting & Professional Services, and Aerospace & Defense, per current listings on Migrate Mate as of July 2026. Indianapolis's outsized K-12 and charter-school sector, combined with a growing life-sciences and healthcare corridor anchored along the 16 Tech innovation district, keeps demand for principals consistent across both education and corporate tracks.
See All 59 Principal Jobs in Indianapolis
Find roles in Indianapolis that match your experience and apply in just a few clicks.
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