Entry Level PRN Nurse Jobs

New grad prn nurse jobs welcome recent graduates and entry level candidates with zero to two years of experience, where strong clinical rotations or internship hours can matter more than a long resume. Most openings are on-site roles across Healthcare & Medical Services, Insurance, and Biotechnology & Pharmaceuticals, with employers like Optum, Medical University of South Carolina, and Prisma Health hiring at this level now.

Find Entry Level PRN Nurse Jobs

Overview

Open roles225+
Top stateSouth Carolina
Top employerOptum
Top cityGreenville, SC
Work type86% On-site
Top industryHealthcare

Showing 5 of 225+ Entry Level PRN Nurse jobs

Hospice Nurse Practitioner - PRN
We won't show you this job again
New 20h ago
Hospice Nurse Practitioner - PRN
Optum
Hermitage, Tennessee
Allied Health
Healthcare Administration
Nursing
$46 - $69/hr
CPR Certification
10,000+

Have you applied for this role?

Registered Nurse (RN) PRN Emergency Services
We won't show you this job again
Added 1d ago
Registered Nurse (RN) PRN Emergency Services
Houston Methodist
Houston, Texas
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
None
10,000+

Have you applied for this role?

Registered Nurse PRN - Home Health
We won't show you this job again
Added 1d ago
Registered Nurse PRN - Home Health
Optum
Vero Beach, Florida
Healthcare Administration
Nursing
Patient Services & Wellbeing
$28 - $50/hr
CPR Certification
10,000+

Have you applied for this role?

Wellness Nurse Manager Flexible $32-39.50 (PRN)
We won't show you this job again
Added 1d ago
Wellness Nurse Manager Flexible $32-39.50 (PRN)
Arrow Senior Living
Stow, Ohio
Healthcare Administration
Nursing
Patient Services & Wellbeing
$32 - $39/hr
51-200

Have you applied for this role?

Registered Nurse - PRN
We won't show you this job again
Added 1d ago
Registered Nurse - PRN
Optum
Inverness, Florida
Healthcare Administration
Nursing
Patient Services & Wellbeing
$68k - $102k/yr
10,000+

Have you applied for this role?

See All 225+ Entry Level PRN Nurse Jobs

Find roles that match your experience and apply in just a few clicks.

Find Entry Level PRN Nurse Jobs

Entry Level PRN Nurse Job Market

Who's Hiring

  • Optum25
  • Medical University of South Carolina17
  • Prisma Health15
  • Houston Methodist8
  • Baptist Health System KY & IN8

Top Industries Hiring

  • Healthcare & Medical Services155
  • Insurance23
  • Biotechnology & Pharmaceuticals4
  • Medical Devices3
  • Science & Research3

Entry Level PRN Nurse Jobs: Frequently Asked Questions

How do I get an entry level prn nurse job?

Start by targeting facilities that explicitly welcome new graduates, such as hospitals with new-grad residency programs or long-term care centers known for training entry level staff. Highlight your clinical rotation hours, any specialty units you trained in, and your active nursing license. PRN roles often value flexibility and availability across multiple shifts, so noting your scheduling openness gives you an edge at this stage.

Which companies hire entry level prn nurses?

Companies hiring entry level prn nurses right now include Optum, Medical University of South Carolina, and Prisma Health, based on current listings on Migrate Mate as of November 2026. At this level, hiring tends to come from hospitals, outpatient clinics, rehabilitation centers, and staffing agencies that maintain large pools of on-call clinical staff.

Are there remote entry level prn nurse jobs?

Yes, though most nursing roles require in-person patient care. About 14% of entry level prn nurse openings are remote or hybrid as of November 2026, and these tend to be telehealth triage, case management support, or health coaching positions that are open to candidates with a valid nursing license and limited prior experience.

Are these new grad prn nurse jobs?

Yes, many of these listings are new grad friendly and open to recent graduates and junior candidates. A posting that welcomes zero to two years of experience, accepts clinical rotations or internship hours in place of full-time work history, or mentions a training period is a strong signal that it suits a new grad entering the field for the first time.

Which industries hire the most entry level prn nurses?

Entry Level prn nurse roles concentrate in Healthcare & Medical Services, Insurance, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at the entry level because they rely on flexible, on-call staffing to manage fluctuating patient volumes without committing to full-time headcount.