Remote Clinical Manager Jobs
Remote Clinical Manager jobs are open across the U.S. at remote-first firms, distributed health networks, and managed care organizations in sectors like telehealth, insurance, and behavioral health. Employers hiring remotely right now include Presence, Brightside Health, and Medpace. See the openings below and apply to the ones that match your experience.
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INTRODUCTION
SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discovery and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
ROLE AND RESPONSIBILITIES
SystImmune is seeking a high quality, ambitious and experienced Senior Clinical Research Associate (CRA) to support SystImmune’s clinical trials. The Sr. CRA is responsible for the management and oversight of their assigned clinical study sites to ensure data quality and patient safety in accordance with ICH-GCP guidelines, local regulations, and applicable SOPs. The Sr CRA must be self-motivated, independent, and able to work in a small team environment. The successful candidate will be a highly organized individual who can also multitask and adjust direction based on changing project/corporate priorities.
- Perform Site Evaluation Visits, Site Initiation Visits, Interim monitoring visits and Close Out Visits.
- Prepare the study reference manual, including liaising with the Contract Research Organization (CRO) team (i.e., central lab, specialty labs and vendors) to ensure efficient preparation and delivery of study materials to investigator sites.
- Responsible for ensuring investigator sites have met all contractual and regulatory requirements for site initiation and first release of study drug.
- Assist in the development of study/program plans (i.e., Monitoring Plan, eCRF Completion Guidelines, Data Management Plan, Safety Management Plan, etc.).
- Manage patient recruitment strategies, proactively identifying barriers to recruitment while proposing solutions (i.e., study-site webinars, newsletters or other potential creative solutions).
- Monitor recruitment, data quality and patient safety while on site and remotely through EDC systems and direct site communication.
- Liaise with study site personnel to ensure timely and correct entry of data into eCRF, including the timely resolution of data queries.
- Maintain project files including ethics committee approvals, curricula vitae of investigators and study personnel, clinical investigators brochure, protocols, case report forms instructions, consent documents, clinical-trial material shipping orders, start-up meeting attendance documentation, letters of agreement, lab reference ranges, and all investigator and site correspondence.
- Identify and complete follow-up of SAEs at study sites.
- Assist with data listing, data coding, patient profile reviews, database lock, and site close-out activities.
- Ensure appropriate and timely submission of documents to the Trial Master File.
- Perform investigational product (IP) inventory, reconciliation and reviews storage and security. Verifies the IP has been dispensed and administered to subjects/patients according to the protocol. Verifies issues or risks associated with blinded or randomized information related to IP.
BASIC QUALIFICATIONS
- Bachelor’s degree in health science or related field.
- 5+ years monitoring Oncology trials independently conducting on-site and remote monitoring visits.
- Excellent verbal and written communication skills required.
- Excellent organizational, multi-tasking and time management skills required.
- Demonstrated experience developing/maintaining site relationships and securing compliance.
- Working knowledge of International Conference on Harmonization Good Clinical Practice guidelines.
- Experienced in Microsoft Office Products (Word, Excel, PowerPoint, SharePoint, Teams) and other clinical trial systems (e.g., CTMS, EDC and eTMF).
- Ability to travel as required (50-75%).
COMPENSATION AND BENEFITS
The expected base salary range for this position is $90,000 - $130,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.
INTRODUCTION
SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discovery and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
ROLE AND RESPONSIBILITIES
SystImmune is seeking a high quality, ambitious and experienced Senior Clinical Research Associate (CRA) to support SystImmune’s clinical trials. The Sr. CRA is responsible for the management and oversight of their assigned clinical study sites to ensure data quality and patient safety in accordance with ICH-GCP guidelines, local regulations, and applicable SOPs. The Sr CRA must be self-motivated, independent, and able to work in a small team environment. The successful candidate will be a highly organized individual who can also multitask and adjust direction based on changing project/corporate priorities.
- Perform Site Evaluation Visits, Site Initiation Visits, Interim monitoring visits and Close Out Visits.
- Prepare the study reference manual, including liaising with the Contract Research Organization (CRO) team (i.e., central lab, specialty labs and vendors) to ensure efficient preparation and delivery of study materials to investigator sites.
- Responsible for ensuring investigator sites have met all contractual and regulatory requirements for site initiation and first release of study drug.
- Assist in the development of study/program plans (i.e., Monitoring Plan, eCRF Completion Guidelines, Data Management Plan, Safety Management Plan, etc.).
- Manage patient recruitment strategies, proactively identifying barriers to recruitment while proposing solutions (i.e., study-site webinars, newsletters or other potential creative solutions).
- Monitor recruitment, data quality and patient safety while on site and remotely through EDC systems and direct site communication.
- Liaise with study site personnel to ensure timely and correct entry of data into eCRF, including the timely resolution of data queries.
- Maintain project files including ethics committee approvals, curricula vitae of investigators and study personnel, clinical investigators brochure, protocols, case report forms instructions, consent documents, clinical-trial material shipping orders, start-up meeting attendance documentation, letters of agreement, lab reference ranges, and all investigator and site correspondence.
- Identify and complete follow-up of SAEs at study sites.
- Assist with data listing, data coding, patient profile reviews, database lock, and site close-out activities.
- Ensure appropriate and timely submission of documents to the Trial Master File.
- Perform investigational product (IP) inventory, reconciliation and reviews storage and security. Verifies the IP has been dispensed and administered to subjects/patients according to the protocol. Verifies issues or risks associated with blinded or randomized information related to IP.
BASIC QUALIFICATIONS
- Bachelor’s degree in health science or related field.
- 5+ years monitoring Oncology trials independently conducting on-site and remote monitoring visits.
- Excellent verbal and written communication skills required.
- Excellent organizational, multi-tasking and time management skills required.
- Demonstrated experience developing/maintaining site relationships and securing compliance.
- Working knowledge of International Conference on Harmonization Good Clinical Practice guidelines.
- Experienced in Microsoft Office Products (Word, Excel, PowerPoint, SharePoint, Teams) and other clinical trial systems (e.g., CTMS, EDC and eTMF).
- Ability to travel as required (50-75%).
COMPENSATION AND BENEFITS
The expected base salary range for this position is $90,000 - $130,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.
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Find Remote Clinical Manager JobsRemote Clinical Manager Job Market
Who's Hiring
- Presence38
- Brightside Health37
- Medpace34
- Center For Autism and Related Disorders21
- Ionian Technologies17
Top Industries Hiring
- Healthcare & Medical Services220
- Biotechnology & Pharmaceuticals127
- Technology & Software106
- Consulting & Professional Services65
- Medical Devices61
What Employers Look For
The qualifications that appear most often in remote clinical manager jobs.
- Active RN license or relevant clinical licensure required in state of practice
- Bachelor's degree in nursing, healthcare administration, or a related clinical field
- Minimum of three to five years of progressive clinical leadership or supervisory experience
- Demonstrated experience with regulatory compliance including Joint Commission or state health department standards
- Proficiency with electronic health record systems such as Epic, Cerner, or Meditech
- Experience managing departmental budgets, staffing schedules, and operational workflows
Tips for Your Remote Clinical Manager Job Search
Highlight async leadership in your application
Remote clinical managers run team huddles, care reviews, and performance check-ins through video calls, messaging platforms, and shared documentation tools. Call out specific tools you've used, such as Teams, Slack, or EHR-based messaging, and describe how you kept distributed teams aligned.
Apply early to remote roles that fit
Migrate Mate lists remote clinical manager openings from across the U.S. in one place, so you can find roles that match your clinical background and apply directly without sorting through unrelated listings.
Frame your resume around measurable remote outcomes
Remote employers can't observe day-to-day performance, so your resume needs to show results, not just duties. Lead with outcomes like caseload size managed, quality metrics improved, or staff retention rates achieved while working in distributed or multi-site environments.
Prepare for the remote workflow interview
Remote clinical manager interviews almost always include scenario questions about managing underperformance, escalations, or compliance issues without face-to-face contact. Practice concrete answers that name the communication channel, the documentation step, and the follow-up you used in past situations.
Verify your licensure covers remote employer locations
Clinical managers working remotely for multistate employers may need licensure in the states where their staff or patients are located, not just their own. Check compact agreement status for your license type and confirm which states your prospective employer operates in before accepting an offer.
Remote Clinical Manager Jobs: Frequently Asked Questions
How do I get a remote clinical manager job?
Target companies that already run distributed clinical teams, such as telehealth platforms, remote-first insurers, and virtual behavioral health providers, because they have the infrastructure for remote clinical oversight. Remote employers screen heavily for written communication, the ability to manage staff and caseloads without in-person contact, and proven self-direction. Candidates who can show experience coordinating care or leading teams across multiple sites or time zones have a clear edge.
Which companies hire remote clinical managers?
Employers currently hiring remote clinical managers include Presence, Brightside Health, and Medpace, per current remote listings on Migrate Mate as of June 2026. Remote clinical manager roles tend to concentrate at telehealth companies, managed behavioral health organizations, remote-first insurance carriers, and distributed home health networks.
Can you get a remote clinical manager job with no experience?
Yes, but remote entry-level clinical manager roles are harder to land because employers expect you to handle independent decision-making from day one without on-site support. Telehealth startups and virtual care platforms are the most open to early-career candidates. Showing structured project ownership, strong async communication, and any team coordination you've done, even informally, can substitute for a formal management title.
Do you need a degree for remote clinical manager jobs?
Usually, but the specific requirement depends on the clinical area and employer. Most remote clinical manager postings require at least a bachelor's degree in nursing, health administration, social work, or a related field, and many prefer a master's. Remote employers also weigh licensure, demonstrated clinical outcomes, and experience managing distributed teams alongside formal credentials.
Which industries hire the most remote clinical managers?
Remote clinical manager roles concentrate in Healthcare & Medical Services, Biotechnology & Pharmaceuticals, and Technology & Software, based on current remote listings on Migrate Mate as of June 2026. These sectors rely on distributed clinical teams and need managers who can coordinate care delivery, quality metrics, and staff performance without a shared physical location.
See All 1,000+ Remote Clinical Manager Jobs
Find roles that match your experience and apply in just a few clicks.
Find Remote Clinical Manager Jobs