Senior Application Analyst Jobs in Massachusetts

Senior Application Analyst jobs in Massachusetts are concentrated in healthcare IT, financial services, and higher education, with demand running from associate-level analysts through senior architects across a market that ranks among the most active in the Northeast. Boston, Cambridge, and Worcester anchor most of the hiring, with established employers like Mass General Brigham, Fidelity Investments, and Blue Cross Blue Shield of Massachusetts regularly filling these roles. The most sought-after specialties in Massachusetts include Epic and Cerner implementation, enterprise resource planning systems, and clinical application support. Find a role that fits below and apply directly.

Find Jobs

Overview

Open roles15
Top employerDana-Farber Cancer Institute
Top cityBoston, MA
Cities hiring7
Work type50% Hybrid
Top industryBiotechnology

Showing 5 of 15+ Senior Application Analyst jobs

Boston Medical Center
PACS Application Analyst III
We won't show you this job again
Boston Medical Center
Added 6d ago
PACS Application Analyst III
Boston Medical Center
Boston, Massachusetts
Business Operations
Product Management
Project Management
$90k - $130k/yr
Bachelor's degree
5,001-10,000

Have you applied for this role?

Boston University
Cash Application Analyst, Research, Finance & Property Management
We won't show you this job again
Boston University
Added 1w ago
Cash Application Analyst, Research, Finance & Property Management
Boston University
Boston, Massachusetts
Business Analysis
Data Analytics
Project Management
Bachelor's degree
10,000+

Have you applied for this role?

Mass General Brigham
Beaker Application Analyst II
We won't show you this job again
Mass General Brigham
Added 1w ago
Beaker Application Analyst II
Mass General Brigham
Somerville, Massachusetts
IT Support & Systems Administration
Healthcare Administration
IT Support
$75k - $110k/yr
Hybrid
Bachelor's
10,000+

Have you applied for this role?

Delan Associates, Inc
Senior Application Support Analyst – Aladdin Front Office
We won't show you this job again
Delan Associates, Inc
Added 2w ago
Senior Application Support Analyst – Aladdin Front Office
Delan Associates, Inc
Boston, Massachusetts
Data Analytics
Data Science
51-200

Have you applied for this role?

Tufts Medicine
Application Analyst lIl - Healthy Planet Certified
We won't show you this job again
Tufts Medicine
Added 3w ago
Application Analyst lIl - Healthy Planet Certified
Tufts Medicine
Burlington, Massachusetts
Communications
Content & Communications
Public Relations (PR)
$101k.26 - $129k.21/yr
Remote (US)
Bachelor's degree in information technology
10,000+

Have you applied for this role?

See All 15 Senior Application Analyst Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Jobs

Senior Application Analyst Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Boston
6 jobs
Burlington
3 jobs
Quincy
1 job
Weymouth
1 job
Somerville
1 job
Charlestown
1 job
Marlborough
1 job

Senior Application Analyst Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute3 open roles
Cadence
Cadence1 open role
Glaukos
Glaukos1 open role

Top Industries Hiring

  • Biotechnology & Pharmaceuticals
  • Healthcare & Medical Services
  • Retail
  • Electronics & Hardware
  • Logistics & Supply Chain

What Massachusetts Employers Look For

The qualifications that appear most often in senior application analyst jobs across Massachusetts.

  • Bachelor's degree in information technology, computer science, or a related field required
  • Five or more years of experience supporting and administering enterprise applications
  • Demonstrated expertise with EHR platforms such as Epic or Cerner in healthcare settings
  • Strong proficiency in SQL, data analysis, and application integration troubleshooting
  • Experience leading system upgrades, user acceptance testing, and go-live support cycles
  • Ability to collaborate with clinical or business stakeholders to translate requirements into solutions

Senior Application Analyst Jobs in Massachusetts: Frequently Asked Questions

How do you become a senior application analyst in Massachusetts?

The most direct path is a bachelor's degree in information technology, computer science, health informatics, or a related field, followed by several years of hands-on application support experience. Massachusetts does not require a state-issued license for this role, but employers in healthcare strongly prefer candidates with Epic or Cerner certifications, which are earned through vendor training programs. Building experience in a junior analyst or IT support role at a Massachusetts hospital system, university, or financial institution is the standard progression to a senior position.

How much do senior application analysts make in Massachusetts?

Senior application analysts in Massachusetts earn a median of about $128,240 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $80,000 for the lowest 10% to over $171,650 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire senior application analysts in Massachusetts?

Employers hiring senior application analysts in Massachusetts right now include Dana-Farber Cancer Institute, Cadence, and Glaukos, based on current listings on Migrate Mate as of August 2026. Massachusetts's dense concentration of academic medical centers, regional health plans, and financial services headquarters makes it one of the more consistent states for ongoing senior application analyst recruitment throughout the year.

Which Massachusetts cities have the most senior application analyst jobs?

Boston, Burlington, and Massachusetts account for the largest share of senior application analyst openings in Massachusetts. Boston and Cambridge drive volume through their concentration of world-class hospitals, biotech firms, and financial institutions, while Worcester's growing healthcare and higher education sector, anchored by UMass Memorial Health and Worcester Polytechnic Institute, supports a steady secondary market outside the Route 128 corridor.

Are there remote senior application analyst jobs in Massachusetts?

Yes, and more than most technical fields, since the role centers on software configuration, documentation, and user support that can largely be done off-site. About 67% of senior application analyst openings tied to Massachusetts are remote or hybrid as of August 2026, reflecting how widely distributed the work can be. Application build tasks, training development, and reporting functions are the portions most consistently offered in a fully remote or hybrid arrangement.

How can I get hired as a senior application analyst in Massachusetts with little or no experience?

The most realistic entry point is an IT help desk, application support specialist, or junior systems analyst role at a Massachusetts employer, where you gain direct exposure to enterprise platforms. Large Massachusetts health systems such as Mass General Brigham and Beth Israel Lahey Health run structured onboarding programs that train new analysts on clinical applications from the ground up. Earning an Epic or Cerner foundation certification before applying signals readiness, and candidates from adjacent roles in healthcare administration or business analysis often transition successfully into entry-level analyst positions.

Where can I find and apply to senior application analyst jobs in Massachusetts?

You can find and apply to senior application analyst jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings updated regularly. Find the roles that fit your experience and apply directly to the employers posting them.

See All 15 Senior Application Analyst Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Jobs