Senior Application Analyst Jobs in Massachusetts
Senior Application Analyst jobs in Massachusetts are open across Boston, Worcester, and Charlestown and other Massachusetts metros, with employers like Dana-Farber Cancer Institute, UMass Memorial Health, and Beth Israel Lahey Health hiring at every experience level. Find a role that fits below and apply directly.
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INTRODUCTION
We are seeking a candidate with in-depth experience supporting Patient Access workflows across both inpatient and outpatient settings, with strong knowledge of Financial Clearance processes. The ideal candidate will have hands-on exposure to real-time eligibility verification, bed management, and service level authorizations, including knowledge of insurance workflows and systems to support prior authorization requirements. Epic Prelude and/or Grand Central certification strongly preferred.
In this role, you will provide day-to-day support for Patient Access business operations while continuously optimizing Epic to maximize workflow efficiency and improve both the end-user and patient experience, recognizing a highly matrixed environment. You will serve as a liaison between end users, operational leaders, IT support teams, and vendors to design, build, support, and enhance Epic solutions in a timely, high-quality manner—triaging and resolving incidents and service requests, troubleshooting workflow and build issues, and identifying root causes and process improvements to prevent recurring problems. You’ll also contribute to project implementations and medium-to-high complexity initiatives by gathering and analyzing requirements, documenting workflows, translating needs into build/configuration, coordinating testing and validation, supporting go-live readiness, and driving post-go-live stabilization and ongoing optimization with minimal guidance. The ideal candidate stays current on industry trends, regulatory and payer requirements, and emerging Epic functionality and third-party solutions, bringing forward recommendations that strengthen compliance, efficiency, and patient access continuity; familiarity with adjacent Epic applications such as Willow, Beacon, Cadence, and/or Ambulatory is strongly valued.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life-changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
PRIMARY DUTIES AND RESPONSIBILITIES
- Application Lifecycle & Technical Leadership: Leads design, development, testing, and maintenance of complex or specialty systems. Ensures system performance, scalability, and regulatory compliance. Drives roadmap input, standardization, and continuous improvement initiatives.
- Business Analysis & Strategic Solution Design: Leads the discovery and translation of complex, cross-functional business requirements into scalable functional and technical solutions. Partners with business and technology stakeholders to define long-term, sustainable strategies that align with enterprise architecture and organizational goals. Analyzes workflows and systems to optimize operational efficiency and business outcomes.
- Testing, Quality & Risk Management: Leads test strategy, planning, and execution for complex enhancements and cross-functional initiatives, ensuring comprehensive validation across upstream, downstream, and integrated systems. Evaluates cross-functional process and data impacts to proactively identify risk, prevent operational disruption, and ensure high-quality, stable releases. Partners with technical teams and business stakeholders to resolve defects, strengthen test coverage, and continuously improve quality assurance practices.
- Operational Support & System Reliability: Oversees system operations including upgrades, enhancements, and integrations. Leads resolution of high-impact incidents and system issues. Improves reliability by conducting root-cause analyses for recurring high-impact incidents, managing corrective action plans, and coordinating with engineering/infra to implement and validate preventive measures. Maintains operational readiness by developing/updating runbooks and support documentation, coordinating on-call procedures, and mentoring others on operational best practices.
- Training, Documentation & Knowledge Transfer: Establishes and maintains training standards, documentation frameworks, and knowledge repositories to ensure consistency, sustainability, and operational readiness. Leads knowledge transfer for new implementations, enhancements, and process changes, ensuring stakeholders and support teams are prepared for adoption. Partners with operational leaders to ensure timely, accurate outward communication of system changes, risks, and adoption guidance.
- Collaboration & Vendor Management: Delivers high-quality, customer-focused support. Leads collaboration with vendors, engineering, and cross-functional teams. Supports enterprise-wide initiatives and integrations.
- Leadership & Mentorship: Provides guidance and mentorship to analysts. Delegates work initiatives and communicates project status to leadership.
KNOWLEDGE, SKILLS AND ABILITIES
- Advanced experience configuring, optimizing, and troubleshooting complex applications.
- Ability to lead small to medium initiatives, prioritize work, and delegate tasks effectively.
- Advanced application configuration, optimization, and performance troubleshooting skills.
- Strong analytical, problem-solving, and communication skills with technical and non-technical audiences.
- Proficiency with Microsoft 365 and project/scheduling tools (e.g., Microsoft Project or Smartsheet).
- Advanced integration and process knowledge; ensures compliance with SDLC, ITIL, and operational standards. May hold ITIL certification.
- Ability to lead multiple workstreams, making decisions to allocate resources and prioritize tasks across projects.
- Deep expertise in one or more application domains (e.g. EHR, ERP, CRM, HRIS); understands complex workflows, dependencies, and operational impacts.
- Participates in change and release management; independently applies integration knowledge to troubleshoot and support workflows.
- Systems thinking, risk assessment, and cross-team coordination capabilities.
MINIMUM JOB QUALIFICATIONS
- High school/GED/Diploma Required.
- Bachelor's degree in Computer Science, Information Systems or a related field preferred.
- 6 years of experience developing, supporting or operating software applications required.
- Experience developing, supporting or operating software applications in a healthcare setting preferred.
LICENSE/CERTIFICATION/REGISTRATION REQUIRED:
- None
SUPERVISORY RESPONSIBILITIES:
- None
PATIENT CONTACT:
- None
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEO Poster
Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$115,800.00 - $127,700.00
See All 13 Senior Application Analyst Jobs in Massachusetts
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Find JobsSenior Application Analyst Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Senior Application Analyst Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
- Dana-Farber Cancer Institute6

- UMass Memorial Health2

- Beth Israel Lahey Health1

- Boston College1

- Brown University Health1

Top Industries Hiring
- Biotechnology & Pharmaceuticals6
- Healthcare & Medical Services4
- Education2
- Technology & Software1
What Massachusetts Employers Look For
The qualifications that appear most often in senior application analyst jobs across Massachusetts.
- Bachelor's degree in computer science, information systems, or a related technical field
- 3 to 7 years of hands-on experience configuring or supporting enterprise business applications
- Proficiency with at least one major platform such as SAP, Workday, Epic, or Salesforce
- Ability to gather and translate business requirements into application design and configuration
- Experience writing or reviewing functional specifications, test plans, and change documentation
- Strong troubleshooting skills for diagnosing application errors, data issues, and integration failures
Senior Application Analyst Jobs in Massachusetts: Frequently Asked Questions
How many senior application analyst jobs are there in Massachusetts?
There are 13+ senior application analyst openings in Massachusetts on Migrate Mate as of June 2026, with the most roles in Boston, Worcester, and Charlestown. New positions post regularly as employers across Massachusetts hire.
How much do senior application analysts make in Massachusetts?
Senior application analysts in Massachusetts earn a median of about $128,240 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $80,000 for the lowest 10% to over $171,650 for the top 10%. Pay rises with experience, specialty, and employer.
Which Massachusetts cities have the most senior application analyst jobs?
Boston, Worcester, and Charlestown have the most senior application analyst openings in Massachusetts right now, with additional roles spread across smaller metros statewide.
Which companies hire senior application analysts in Massachusetts?
Employers hiring senior application analysts in Massachusetts include Dana-Farber Cancer Institute, UMass Memorial Health, and Beth Israel Lahey Health, based on current listings on Migrate Mate as of June 2026.
Are there remote senior application analyst jobs in Massachusetts?
Yes. About 38% of senior application analyst openings tied to Massachusetts are remote or hybrid as of June 2026. The rest are on-site roles based in Massachusetts metros.
How do I apply for senior application analyst jobs in Massachusetts?
You can apply to senior application analyst jobs in Massachusetts directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Massachusetts location, then apply to each one that fits.
See All 13 Senior Application Analyst Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
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