Senior Application Analyst Jobs in California
Senior Application Analyst jobs in California are among the most active in the country, with steady demand concentrated in enterprise technology, healthcare systems, and financial services across every experience level from associate through principal. The strongest hiring is in the San Francisco Bay Area, Los Angeles, and San Diego, where established employers such as Kaiser Permanente, Salesforce, and Wells Fargo regularly seek analysts with expertise in ERP integrations, cloud platforms, and clinical or financial application support. Workday configuration, ServiceNow administration, and Epic systems specialization are among the most consistently requested skills in California listings. Find a role that fits below and apply directly.
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At Exact Sciences, we’re helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you’re working to help others.
Position Overview
The Senior Application Analyst will work on software design, configurations, upgrades, and improvements. As the primary support contact for application end-users, the Senior Application Analyst will work to identify issues that arise in the Production Planning, Digital Manufacturing and Quality management areas, as well as issues that impact other application teams, and work to resolve them. This role will guide workflow design, build, and test systems and analyze other technical issues associated with the lab operation and/or business software. The Senior Application Analyst supports the application or Project Manager and has responsibility for the scope, schedule, and quality of the software project in relation to the applications.
The Senior Application Analyst plays a critical role in managing and optimizing our Digital Manufacturing platform, primarily PPDS, Digital Manufacturing, Quality Management in SAP. This role is expected to have a high-level understanding of business processes, systems and integration methodologies. The Senior Application Analyst will have an in-depth knowledge of PPDS, Digital manufacturing and Quality management SAP configuration surrounding Manufacturing capabilities. They will have a proven ability to lead and mentor a team of analysts, providing guidance and support. This role will require a strong focus on providing excellent support to end-users, as well as effective communication and collaboration skills to work with cross-functional teams and external partners.
We're committed to staying at the forefront of SAP — currently migrating to RISE with SAP, deploying HANA 2025, already leveraging enterprise-wide Fiori, and preparing to launch Joule and SAP Business AI. If you're an SAP professional who wants to work with cutting-edge tools — not legacy systems — and be part of a team that prioritizes staying ahead of the curve, this is your opportunity. Come build something current — right here in Madison.
Essential Duties
Include, but are not limited to, the following:
- Responsible for business systems design and configuration, and upgrades and improvements for low to medium complexity applications.
- Design and implement solutions to a wide range of difficult problems that are imaginative, thorough, and practical.
- Responsible for independent development and configuration of an assigned application.
- Identify issues that arise in the application area as well as issues that impact other application teams, and work to resolve them.
- Develop new processes and procedures to meet current challenges.
- Create and maintain system documentation.
- Lead the estimation of enhancement or support requests.
- Guide workflow design, configure and test system changes, and analyze technical issues.
- Liaise with business systems stakeholders and software vendor’s implementation staff to ensure alignment of business needs with the delivery of system changes.
- Develop an understanding of operational needs to set the direction for the organization's workflows; proactively identify opportunities to improve business workflow with technology improvements.
- Participate in developing documentation and participate in trainings and work with end users.
- Troubleshoot problems and questions and provide regular updates on status to key business stakeholders.
- Serve as a subject matter expert of assigned applications.
- Provide end-user production support for issues entered into issue tracking systems.
- Review the status of projects and issues with project leadership.
- Assign or delegate configuration or other activities to other team members.
- Act as delegate for leadership regarding incident or problem resolution.
- Provide mentorship for other peers and take the lead to solve problems, even if outside of normal scope.
- Lead internal process design and documentation to drive continuous improvement for the IT department or team.
- Ability and willingness to take ownership of work activities and ensure that they are done in a timely, accurate, and efficient manner.
- Ability and willingness to recognize assignments or tasks that need to be completed, to seek out additional assignments or tasks, and to help others.
- Ability to communicate information clearly and concisely with project leadership, subject matter experts, and key stakeholders.
- Ability to persevere in difficult situations, overcome obstacles, and reach high levels of performance when faced with stressful work situations and time pressures.
- Ability and willingness to learn new software applications.
- Apply flexibility with respect to changing end-user business needs.
- Apply strong analytical skills, business intuition, and organizational ability.
- Apply strong problem-solving skills.
- Apply excellent interpersonal and communication skills.
- Ability to operate in a cross-functional and complex matrix environment.
- Ability to be adaptable, open to change, able to work in ambiguous situations, and respond to new information or unexpected circumstances.
- Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
- Support and comply with the company’s Quality Management System policies and procedures.
- Maintain regular and reliable attendance.
- Ability to act with an inclusion mindset and model these behaviors for the organization.
- Ability to work nights and/or weekends, as needed.
- Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 90% of a typical working day.
- Ability and means to travel between local Exact Sciences locations.
- Ability to travel 5% of working time away from work location, may include overnight/weekend travel.
Minimum Qualifications
- Bachelor’s Degree in Computer Science, Information Systems, or related field as outlined in the essential duties; or High School Diploma or General Education Degree (GED) and 12 years of relevant experience as outlined in the essential duties in lieu of Bachelor’s Degree.
- 5+ years of experience developing or configuring technology solutions, either in an application analyst or project delivery role.
- Demonstrated ability to understand and apply industry best practices.
- Strong computer skills to include internet navigation and email usage.
- Proficient in Microsoft Office programs.
- Demonstrated ability to perform the essential duties of the position with or without accommodation.
Preferred Qualifications
- In-depth knowledge of PPDS, Digital Manufacturing and Quality Management design and configuration in SAP.
- In-depth knowledge of SAP MM/PP design and configuration.
- Experience leading teams of analysts and directing work of others.
- Understanding of integration points between PPDS, Digital Manufacturing and Quality modules of SAP.
- Experience leading complex projects and coordinating work amongst a cross-functional team.
Salary Range:
National Range: $91,000-$155,000
Redwood City Range: $155,200-194,000
The annual base salary shown is for this position located in US - WI - Madison on a full-time basis and may differ by hiring location. In addition, this position is bonus eligible.
Exact Sciences is proud to offer an employee experience that includes paid time off (including days for vacation, holidays, volunteering, and personal time), paid leave for parents and caregivers, a retirement savings plan, wellness support, and health benefits including medical, prescription drug, dental, and vision coverage. Learn more about our benefits.
Our success relies on the experiences and perspectives of a diverse team, and Exact Sciences fosters a culture where all employees can develop personally and professionally with a sense of respect and belonging. If you require an accommodation, please contact us here.
Not ready to apply? Join our Talent Community to stay updated on the latest news and opportunities at Exact Sciences.
We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to disability, protected veteran status, and any other status protected by applicable local, state, or federal law.
To view the Right to Work, E-Verify Employer, and Pay Transparency notices and Federal, Federal Contractor, and State employment law posters, visit our compliance hub. The documents summarize important details of the law and provide key points that you have a right to know.
See All 16 Senior Application Analyst Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
Find JobsSenior Application Analyst Jobs by City in California
Where California roles are concentrated, by current openings.
Senior Application Analyst Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring
- Exact Sciences2

- University of California - San Francisco2

- AMD1

- ASML1

- Adobe1

Top Industries Hiring
- Healthcare & Medical Services6
- Technology & Software3
- Biotechnology & Pharmaceuticals2
- Education2
- Electronics & Hardware2
What California Employers Look For
The qualifications that appear most often in senior application analyst jobs across California.
- Bachelor's degree in information systems, computer science, or a related technical field
- Five or more years of experience supporting or configuring enterprise applications at scale
- Hands-on proficiency with ERP, CRM, or ITSM platforms such as Workday, SAP, or ServiceNow
- Experience gathering business requirements and translating them into functional system specifications
- Strong background in application troubleshooting, root cause analysis, and production support
- Familiarity with ITIL frameworks and change management processes in regulated California industries
Senior Application Analyst Jobs in California: Frequently Asked Questions
How do you become a senior application analyst in California?
Most senior application analyst roles in California require a bachelor's degree in information systems, business administration, or computer science, paired with several years of hands-on application support experience. California employers, particularly in healthcare, often require platform-specific certifications such as Epic proficiency or Workday credentials rather than a state-issued license. Candidates who build depth in one enterprise platform and move from analyst to lead roles at California hospital systems, tech firms, or financial institutions tend to reach senior level most efficiently.
How much do senior application analysts make in California?
Senior application analysts in California earn a median of about $127,720 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $79,110 for the lowest 10% to over $181,770 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire senior application analysts in California?
Employers hiring senior application analysts in California right now include Exact Sciences, University of California - San Francisco, and AMD, based on current listings on Migrate Mate as of June 2026. California's concentration of large healthcare networks, technology headquarters, and financial institutions means demand stays consistent across both the Bay Area and Southern California throughout the year.
Which California cities have the most senior application analyst jobs?
San Francisco, San Jose, and Redwood City have the most senior application analyst openings in California. The Bay Area leads because it is home to major technology headquarters and large regional health systems, while Los Angeles draws volume from entertainment conglomerates, sprawling hospital networks, and a large financial services sector, and San Diego's defense contractors and biotech companies keep consistent demand in place.
Are there remote senior application analyst jobs in California?
Yes, and more than most fields. Senior application analyst work is largely desk-based and systems-driven, making it well suited to distributed teams. About 19% of senior application analyst openings tied to California are remote or hybrid as of June 2026, reflecting how broadly California employers have adopted flexible arrangements for this role. Configuration, reporting, and second-tier support work tends to be the most consistently remote, while go-live projects and stakeholder training often require on-site presence.
How can I get hired as a senior application analyst in California with little or no experience?
The most realistic entry path is landing a junior application analyst or IT support specialist role at a large California employer, then building platform depth from there. Healthcare systems such as Sutter Health and Dignity Health run structured associate analyst programs that bring in candidates without deep enterprise experience. Moving laterally from a business analyst, help desk lead, or systems administrator position is also common. Earning a vendor certification in Workday, ServiceNow, or Epic before applying gives candidates a concrete credential that California employers recognize as a signal of readiness.
Where can I find and apply to senior application analyst jobs in California?
You can find and apply to senior application analyst jobs in California on Migrate Mate, which lists current California openings sourced from employers actively hiring in the state. Find roles that match your platform experience and seniority level, then apply directly to the ones that fit.
See All 16 Senior Application Analyst Jobs in California
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