Senior Automation Specialist Jobs in Massachusetts
Senior Automation Specialist jobs in Massachusetts are concentrated in the life sciences, advanced manufacturing, and defense sectors, with Boston, Lowell, and Worcester accounting for the largest share of openings. Employers such as Raytheon Technologies, Thermo Fisher Scientific, and Boston Scientific maintain a steady presence and consistently recruit at the senior level for candidates who can own complex automation programs end to end. Programmable logic controllers, robotics integration, and MES platform expertise are the most in-demand specialties across the state. Scan the live roles below and apply to whichever ones fit.
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Zifo is a global specialist scientific and process informatics services company supporting life sciences, biotech, and pharmaceutical organizations. We enable digital transformation across R&D, manufacturing, and quality by delivering data-driven, scalable, and compliant software solutions.
Zifo is seeking an experienced Scientific Automation Lead to drive the design, architecture, and delivery of scalable, compliant automation solutions across scientific and laboratory workflows. The role sits at the intersection of science, laboratory informatics, data, integration, cloud, and automation technologies, partnering with scientists, laboratory users, technical teams, and client stakeholders to identify automation opportunities and translate complex experimental workflows into robust, production-ready solutions spanning scientific system integrations, data components, workflow orchestration, AI-enabled capabilities, and next-generation data pipelines.
The Automation Lead will provide technical leadership across solution architecture, integration strategy, automation frameworks, testing, CI/CD, production readiness, and delivery, while mentoring engineering teams, establishing reusable automation patterns and accelerators, managing technical dependencies, and serving as a key technical interface with clients. Experience with Benchling, LIMS, ELN, SDMS, CDS, enterprise data platforms, and strong expertise in Python, APIs, AWS, and modern software engineering practices will be highly valued.
Requirements
- Own end-to-end automation initiatives, from discovery, technical assessment, and solution strategy through architecture, implementation, deployment, and production support, ensuring solutions are scalable, reusable, and aligned with business and scientific objectives.
- Drive the development of integrated automation solutions across laboratory workflows, scientific systems, data platforms, workflow orchestration, and AI/ML capabilities, collaborating effectively with scientists, technical teams, and client stakeholders.
- Design and develop automation frameworks, APIs, microservices, integrations, and data pipelines using Python, FastAPI, AWS, and modern cloud technologies.
- Lead integration with scientific and enterprise platforms such as Benchling, LIMS, ELN, SDMS, CDS, and enterprise data platforms using API, file-based, event-driven, and other integration patterns.
- Drive automation of data ingestion, transformation, validation, reconciliation, workflow execution, and data movement across laboratory and downstream systems.
- Establish reusable frameworks, components, accelerators, and engineering standards, while leading testing, CI/CD, deployment, monitoring, troubleshooting, and production-readiness practices.
- Ensure solutions meet security, data integrity, performance, auditability, and regulatory requirements, including GxP and 21 CFR Part 11 where applicable.
- Provide technical leadership and mentorship through architecture and design reviews, code reviews, technical problem solving, performance optimization, and guidance to automation engineers.
- Manage technical delivery, including estimates, dependencies, risks, resource needs, cross-team coordination, and delivery status across geographically distributed teams; serve as a technical point of contact for clients and communicate solution approaches, recommendations, and trade-offs.
- Drive continuous improvement and innovation by evaluating automation, AI/ML, workflow orchestration, and cloud technologies, while maintaining clear technical documentation covering architecture, integrations, APIs, workflows, testing, deployment, and operations using JIRA, Confluence, or equivalent tools.
Required Qualifications
- Bachelor’s or Master’s degree in engineering, Life Sciences, or a related field, with 6+ years of experience in automation, software engineering, and technical development, 3+ years of experience in customer/client engagement and relationship management, and 3+ years of experience in technical/team leadership and mentoring.
- Strong hands-on experience with Python, FastAPI, REST APIs, microservices, automation frameworks, and scientific/enterprise system integrations, with experience using frameworks and tools such as pytest, Apache Airflow, Prefect, or equivalent workflow orchestration technologies
- Strong experience with SQL, data modeling, relational databases, and familiarity with NoSQL databases.
- Strong AWS experience, including S3, EC2, Lambda, Step Functions, RDS/Aurora, IAM, monitoring, and logging.
- Experience with data pipelines, ETL/ELT, data validation, workflow automation, and system integrations.
- Strong understanding of Git, CI/CD, automated testing, Docker, DevOps, and modern software development practices.
- Experience with testing frameworks such as pytest/unittest, including unit, integration, API, and end-to-end testing.
- Working knowledge of AI/ML concepts and data/ML libraries such as pandas, NumPy, and scikit-learn; TensorFlow/PyTorch is a plus.
- Strong understanding of software architecture, design patterns, integration patterns, Agile/Scrum, SDLC, and cloud deployment practices.
- Experience working in regulated environments, with knowledge of GxP, 21 CFR Part 11, data integrity, audit trails, validation, and change management.
- Demonstrated ability to lead technical teams, mentor engineers, conduct technical reviews, and establish engineering standards.
- Strong communication, stakeholder management, problem-solving, client-facing, and cross-functional leadership skills.
Additional Preferences
- Experience working with global, geographically distributed teams and managing cross-team dependencies.
- Experience with scientific and laboratory systems such as Benchling, LIMS, ELN, SDMS, CDS, or similar platforms; life sciences/pharmaceutical experience preferred.
- Experience developing reusable automation frameworks, accelerators, and integration patterns.
- Experience working directly with scientists, assay teams, laboratory users, and business stakeholders.
- Experience with technical estimation, client workshops, discovery sessions, solution proposals, or pre-sales activities.
- Willingness to travel/ relocate based on project or business needs
Benefits
CURIOSITY DRIVEN, SCIENCE FOCUSED, EMPLOYEE BUILT. Our culture is unlike any other, one where we debate, challenge ourselves, and interact with all alike. We are a curious bunch, characterized by our passion to learn and spirit of teamwork. Zifo is a global R&D solutions provider focused on the industries of Pharma, Biotech, Manufacturing QC, Medical Devices, specialty chemicals and other research-based organizations. Our team’s knowledge of science and expertise in technology help Zifo better serve our customers around the globe, including 18 of the Top 20 Biopharma companies.
We look for Science – Biotechnology, Pharmaceutical Technology, Biomedical Engineering, Microbiology etc. We possess scientific and technical knowledge and bear professional and personal goals. While we have a “no doors” policy to promote free access within, we do have a tough door to walk in. We search with a two-point agenda – technical competency and cultural adaptability.
We offer a competitive compensation package including accrued vacation, medical, dental, vision, 401k with company matching, life insurance, and flexible spending accounts.
If you share these sentiments and are prepared for the atypical, then Zifo is your calling!
Zifo is an equal opportunity employer, and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
See All 23 Senior Automation Specialist Jobs in Massachusetts
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Where Massachusetts roles are concentrated, by current openings.
Senior Automation Specialist Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Medical Devices
- Electronics & Hardware
What Massachusetts Employers Look For
The qualifications that appear most often in senior automation specialist jobs across Massachusetts.
- Bachelor's degree in electrical engineering, mechatronics, or a closely related field required
- Hands-on experience with Allen-Bradley or Siemens PLC programming in a production environment
- Proven ability to design, commission, and validate automated systems from concept through launch
- Proficiency with robotics platforms such as FANUC, KUKA, or Universal Robots
- Familiarity with FDA 21 CFR Part 11 and GMP validation protocols for regulated Massachusetts industries
- Strong project leadership skills including cross-functional coordination and vendor management
Senior Automation Specialist Jobs in Massachusetts: Frequently Asked Questions
How do you become a senior automation specialist in Massachusetts?
The most direct path is a bachelor's degree in electrical engineering, mechatronics, or systems engineering followed by several years of hands-on automation experience in a regulated industry. Massachusetts does not issue a state-specific license for this role, but employers in the life sciences sector routinely expect familiarity with FDA validation requirements and ISA Certified Control Systems Technician or Certified Automation Professional credentials, which carry real weight with hiring managers at Massachusetts manufacturers and biopharma companies.
Which companies hire senior automation specialists in Massachusetts?
Companies currently hiring senior automation specialists in Massachusetts include Moderna, Siemens, and Amazon, per current listings on Migrate Mate as of October 2026. Massachusetts's dense concentration of biopharma manufacturers, defense contractors, and medical device firms means demand at the senior level tends to stay consistent even when broader hiring slows.
Which Massachusetts cities have the most senior automation specialist jobs?
Boston, Cambridge, and Canton lead Massachusetts for senior automation specialist openings. Boston draws the largest volume through its biopharma and medtech corridor, Lowell reflects the region's advanced manufacturing and defense heritage anchored by large contractors, and Worcester benefits from its growing life sciences campus development and proximity to several major medical device producers.
Are there remote senior automation specialist jobs in Massachusetts?
Yes, but they're rare. About 50% of senior automation specialist openings tied to Massachusetts are remote or hybrid as of October 2026, reflecting the hands-on nature of most automation work. The portions of the role most likely to go remote are systems architecture design, documentation, and vendor coordination, while commissioning, validation, and floor troubleshooting almost always require an on-site presence.
How can I get hired as a senior automation specialist in Massachusetts with little or no experience?
The most realistic entry point is a controls technician or automation engineer associate role, which many Massachusetts manufacturers and biopharma companies use as a pipeline into senior positions. Large employers in the Route 128 and Route 495 corridors regularly hire from co-op and internship programs tied to institutions such as Northeastern University and WPI. Building a portfolio around a personal PLC or HMI project and earning an ISA Certified Control Systems Technician credential gives candidates a concrete edge over applicants with credentials alone.
Where can I find and apply to senior automation specialist jobs in Massachusetts?
You can find and apply to senior automation specialist jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings in one place. Search the roles available, find the ones that match your background and target location, and apply directly through each listing without any extra steps in between.
See All 23 Senior Automation Specialist Jobs in Massachusetts
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