Staff Software Engineer Jobs in Tennessee
Staff Software Engineer jobs in Tennessee are in strong demand, concentrated in healthcare technology, fintech, logistics software, and enterprise SaaS, with openings at every level from mid-career engineers stepping up to seasoned technical leads. Nashville, Knoxville, and Memphis are the primary hiring metros, home to major employers such as HCA Healthcare, FedEx, and Asurion, all of which maintain substantial engineering organizations in the state. The most sought-after specialties include distributed systems, cloud infrastructure, and backend platform engineering. Find a role that fits below and apply directly.
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We are seeking a Senior Staff Software Engineer to help architect and build the data platform and backend services for our healthcare SaaS solutions. This is a hands-on technical leadership role requiring deep expertise in database and data architecture, cloud-native backend development, scalability, security, and healthcare interoperability.
The ideal candidate combines strong software engineering skills with the ability to design secure, high-performance data architectures for large-scale, multi-tenant applications handling sensitive healthcare data.
Key Responsibilities
- Architect and develop scalable backend services and data platforms for multi-tenant SaaS applications.
- Design and optimize relational and non-relational database architectures, data models, and storage strategies.
- Build scalable data ingestion, integration, and processing capabilities for large and complex healthcare datasets.
- Design cloud-native data architectures incorporating databases, data lakes/lakehouses, and distributed data platforms.
- Develop APIs and integration capabilities supporting healthcare interoperability, including HL7 and FHIR.
- Ensure appropriate architecture for security, encryption, access control, auditability, data governance, retention, and regulatory compliance.
- Design for high availability, disaster recovery, performance, and scalability.
- Provide technical leadership and architectural guidance while remaining hands-on with design and development.
- Collaborate with Software Engineering, Product, Security, Quality, and Regulatory teams.
Required Qualifications
- Bachelor’s or Master’s degree in Computer Science, Engineering, Information Systems, or related field.
- 10+ years of software engineering experience, including significant backend and data-platform development.
- Deep experience designing and optimizing relational databases such as PostgreSQL, SQL Server, or MySQL.
- Experience with NoSQL technologies such as MongoDB, Cosmos DB, or equivalent.
- Strong experience with cloud platforms (Azure, AWS, or GCP) and cloud-native architectures.
- Experience with modern data pipelines, ingestion frameworks, data lakes/lakehouses, and distributed data architectures.
- Strong understanding of multi-tenant SaaS architecture, APIs, scalability, security, and data governance.
- Experience designing systems that handle sensitive or regulated data.
Preferred Qualifications
- Healthcare software or regulated-industry experience.
- Experience with HL7, FHIR, EHR/EMR integration, or healthcare interoperability.
- Experience with Databricks, Azure Data Factory, Kafka, Spark, or similar technologies.
- Experience with containerized environments such as Docker and Kubernetes.
Compensation and Benefits
The salary range estimated for this position based in Indiana is $135,800.00–$203,750.00.This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
See All 6 Staff Software Engineer Jobs in Tennessee
Find roles in Tennessee that match your experience and apply in just a few clicks.
Find Staff Software Engineer JobsStaff Software Engineer Jobs by City in Tennessee
Where Tennessee roles are concentrated, by current openings.
Staff Software Engineer Job Market in Tennessee
A snapshot from current Tennessee openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Insurance
- Healthcare & Medical Services
What Tennessee Employers Look For
The qualifications that appear most often in staff software engineer jobs across Tennessee.
- Bachelor's or master's degree in computer science, software engineering, or a related field
- Seven or more years of professional software engineering experience in production environments
- Demonstrated ability to lead technical design, architecture decisions, and code review processes
- Proficiency in at least one major backend language such as Java, Python, Go, or Scala
- Experience with cloud platforms like AWS, Azure, or Google Cloud in an enterprise setting
- Strong cross-functional collaboration skills working with product managers and engineering leadership
Staff Software Engineer Jobs in Tennessee: Frequently Asked Questions
How do you become a staff software engineer in Tennessee?
The standard path to a staff software engineer role in Tennessee is a bachelor's degree in computer science, software engineering, or a closely related discipline, followed by several years of progressive engineering experience. Tennessee does not require a state-issued license for software engineers. Employers here typically promote engineers to the staff level after they demonstrate consistent technical leadership, cross-team influence, and ownership of significant system design. Building depth in an in-demand specialization such as cloud architecture or distributed systems strengthens a candidacy.
How much do staff software engineers make in Tennessee?
Staff software engineers in Tennessee earn a median of about $122,430 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $75,280 for the lowest 10% to over $166,380 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire staff software engineers in Tennessee?
Employers hiring staff software engineers in Tennessee right now include CVS Health, Zeta Global, and Williams-Sonoma, based on current listings on Migrate Mate as of November 2026. Tennessee's concentration of healthcare technology companies, logistics platforms, and financial services firms means demand for senior engineering talent is distributed across both large headquarters and regional development centers throughout the state.
Which Tennessee cities have the most staff software engineer jobs?
Tennessee, Memphis, and Nashville have the most staff software engineer openings in Tennessee. Nashville leads because of its dense cluster of healthcare IT companies, fintech startups, and corporate engineering hubs, while Knoxville's openings are shaped by its manufacturing technology and university-linked research employers, and Memphis draws demand from logistics and supply-chain software organizations anchored by large distribution and freight companies headquartered there.
Are there remote staff software engineer jobs in Tennessee?
Yes, and more than most fields. About 100% of staff software engineer openings tied to Tennessee are remote or hybrid as of November 2026, reflecting how naturally this role translates to distributed work. The portions of the role most likely to stay fully remote are independent architecture work and asynchronous code review, while on-site or hybrid arrangements tend to appear when the employer requires close coordination with embedded product or infrastructure teams.
How can I get hired as a staff software engineer in Tennessee with little or no experience?
The most realistic entry path is securing a software engineer role at a mid-size or enterprise Tennessee employer and building toward staff-level responsibilities over time. HCA Healthcare, Asurion, and Tennessee-based fintech companies such as Reliant Bank's technology division run new-graduate and associate engineer programs that develop engineers from the ground up. Moving from a senior engineer or technical lead position in an adjacent domain, or building a strong portfolio demonstrating system design and architecture thinking, accelerates the path significantly.
Where can I find and apply to staff software engineer jobs in Tennessee?
You can find and apply to staff software engineer jobs in Tennessee on Migrate Mate, which lists current Tennessee openings updated on an ongoing basis. Find roles that fit your background and apply directly to the employers posting them. No sign-up is required to view listings.
See All 6 Staff Software Engineer Jobs in Tennessee
Find roles in Tennessee that match your experience and apply in just a few clicks.
Find Staff Software Engineer Jobs