Technical Specialist Jobs in California
Technical Specialist jobs in California concentrate in the technology, defense, semiconductor, and life sciences sectors, with demand at every level from entry-level field support to senior systems engineering. The largest hiring markets are the San Francisco Bay Area, Los Angeles, and San Diego, where companies such as Lockheed Martin, Qualcomm, and Hewlett Packard Enterprise maintain major operations and ongoing technical specialist needs. The most in-demand specialties right now are network and infrastructure support, medical device service, and semiconductor process engineering. See the openings below and apply to the ones that match your experience.
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Senior Sales Specialist – High-Plex Sequencing
Location: Field-Based / Flexible with location.
We have 2 new exciting opportunities, one for the East Coast and one for the West coast.
Position Overview:
Applied Biosystems has a long and proud history in DNA sequencing. From laying the backbone with Sanger sequencing to advancing current next-generation sequencing workflows, our brand is built on science and trusted performance. Now, as we accelerate our growth in NGS library preparation and expand our footprint into High-Plex Sequencing, we are looking for a key player to help shape the future of this business with us.
This is not a traditional sales role. As our High-Plex Sequencing Sales Specialist, you will serve as a foundational pillar for our NGS strategy. You will work with us to develop end-to-end workflows, and market strategy, acting as both a technical authority and a growth catalyst across key market segments. If you know the NGS landscape inside and out, understand the nuances of library prep chemistry, and want to help build and guide a high-growth portfolio, this is where you can make a lasting impact.
Requirements:
BS degree required, preferred field of study in the Life Sciences
8 plus years of technical sales experience in life sciences is strongly preferred
How You Will Make an Impact:
- Shape the Strategy & Market Growth: Partner directly with research and clinical customers to expand our High-Plex Sequencing footprint. You will help drive market adoption of our NGS library prep solutions, identifying emerging trends, customer needs, and workflow gaps to influence our commercial approach.
- Serve as the High-Plex Expert: Translate complex chemistry, assays, and sequencing workflows into consultative solutions. Whether guiding a lab through library preparation optimization or presenting at industry conferences, you will be the trusted technical authority for our scientific community and internal partners.
- Drive Strategic Customer Success: Build deep, lasting relationships with key opinion leaders, sequencing core facilities, and commercial accounts. You will manage complex, consultative sales cycles from initial engagement through technical demonstration and final implementation.
- Collaborate Across the Business: Work in close partnership with field application scientists, product management, and regional sales teams in a matrixed environment to ensure seamless customer onboarding, robust pipeline execution, and sustained revenue growth.
What You Bring to the Team:
- Deep NGS Expertise: You have a thorough, hands-on understanding of next-generation sequencing chemistry, high-plex target enrichment, sample prep, and end-to-end library preparation workflows. You know the players, the platforms, and the commercial landscape.
- Proven Commercial Success: You hold a Bachelor’s degree in Life Sciences, Chemistry, Genetics, or a related field, combined with at least 5 years of successful technical sales or field application experience in life science research instruments and reagents.
- Consultative Problem Solver: You excel at navigating complex sales cycles, leading technical discussions with principal investigators and lab directors, and tailoring solutions to specific market segments.
- Strategic Vision & Execution: You have a track record of territory planning, market analysis, and cross-functional leadership, with the organizational skill to manage high-touch customer relationships alongside internal strategic initiatives.
- Mobility & Engagement: You are comfortable traveling up to 50 to 75 percent within the assigned territory to meet customers in their labs, present at conferences, and host targeted workflow sessions. Bilingual communication skills are a welcome advantage.
Compensation and Benefits
This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
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Where California roles are concentrated, by current openings.
Technical Specialist Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Technology & Software
- Healthcare & Medical Services
- Science & Research
- Staffing & Recruiting
- Manufacturing
What California Employers Look For
The qualifications that appear most often in technical specialist jobs across California.
- Associate or bachelor's degree in engineering, electronics, or a closely related technical field
- Hands-on experience diagnosing and repairing hardware, software, or electromechanical systems
- Proficiency with industry-standard diagnostic tools and technical documentation platforms
- Relevant vendor or industry certification such as CompTIA, Cisco, or manufacturer-specific credentials
- Ability to work on-site at California customer or field locations with minimal supervision
- Strong written and verbal communication skills for creating service reports and training users
Technical Specialist Jobs in California: Frequently Asked Questions
How do you become a technical specialist in California?
Most technical specialist roles in California require at least an associate degree in electronics, engineering technology, computer science, or a related field, with a bachelor's degree preferred for senior positions. California does not issue a single statewide license for the general technical specialist title, but specialties do carry credential requirements: medical device service technicians working on certain equipment may need to meet California Department of Public Health standards, and electrical work on some systems requires a California contractor license through the Contractors State License Board. Vendor certifications from Cisco, CompTIA, or equipment manufacturers strengthen any application significantly.
Which companies hire technical specialists in California?
Companies currently hiring technical specialists in California include Sutter Health, Thermo Fisher Scientific, and Lucid Motors, per current listings on Migrate Mate as of November 2026. California's concentration of defense contractors in the Los Angeles and San Diego corridors, semiconductor firms in Silicon Valley, and large health systems across the state means technical specialist demand is broad and distributed across multiple industries.
Which California cities have the most technical specialist jobs?
San Diego, Irvine, and San Francisco account for the highest concentration of technical specialist openings in California. The Bay Area leads because of its dense cluster of technology and semiconductor companies, Los Angeles draws heavily from aerospace and defense contractors such as Northrop Grumman and Raytheon, and San Diego's strength in biotech, wireless communications, and naval defense installations makes it a consistent source of specialized technical roles.
Are there remote technical specialist jobs in California?
Yes, but they're relatively rare, because most technical specialist work is hands-on and tied to physical equipment, lab environments, or customer sites. About 53% of technical specialist openings tied to California are remote or hybrid as of November 2026, and those positions tend to be concentrated in roles focused on software configuration, technical documentation, or remote diagnostics rather than field service or hardware installation.
How can I get hired as a technical specialist in California with little or no experience?
The most realistic entry path is through an associate-level support or field technician role, which large California employers use as a pipeline into specialist positions. Companies such as Kaiser Permanente, Apple, and defense contractors in the Los Angeles and San Diego regions run new-associate programs and rotational technical trainee tracks open to candidates with a two-year technical degree or a strong CompTIA A+ or Network+ certification. Community college programs through the California Community Colleges system offer hands-on lab coursework that many California employers explicitly recognize, and lateral moves from help desk analyst or lab technician positions are a common entry point.
Where can I find and apply to technical specialist jobs in California?
You can find and apply to technical specialist jobs in California on Migrate Mate, which lists current California openings updated regularly. Search the listings to find roles that match your experience level, specialty, and preferred location, then apply directly to the ones that fit.
See All 156+ Technical Specialist Jobs in California
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